Response of choline metabolites to docetaxel therapy is quantified in vivo by localized (31)P MRS of human breast cancer xenografts and in vitro by high-resolution (31)P NMR spectroscopy of cell extracts.

abstract：PURPOSE:To investigate for the first time the feasibility of aortic four-dimensional (4D) flow at 7T, both contrast enhanced (CE) and non-CE. To quantify the signal-to-noise ratio (SNR) in aortic 4D flow as a function of field strength and CE with gadobenate dimeglumine (MultiHance). METHODS:Six healthy male volunteer...

journal_title：Magnetic resonance in medicine

authors： Hess AT,Bissell MM,Ntusi NA,Lewis AJ,Tunnicliffe EM,Greiser A,Stalder AF,Francis JM,Myerson SG,Neubauer S,Robson MD

更新日期：2015-05-01 00:00:00

abstract：PURPOSE:To use the variable delay multipulse (VDMP) chemical exchange saturation transfer (CEST) approach to obtain clean amide proton transfer (APT) and relayed Nuclear Overhauser enhancement (rNOE) CEST images in the human brain by suppressing the conventional magnetization transfer contrast (MTC) and reducing the di...

journal_title：Magnetic resonance in medicine

authors： Xu X,Yadav NN,Zeng H,Jones CK,Zhou J,van Zijl PC,Xu J

更新日期：2016-01-01 00:00:00

abstract：:A method for calculating quantitative three-dimensional susceptibility maps from field measurements acquired using gradient echo imaging at high field is presented. This method is based on division of the three-dimensional Fourier transforms of high-pass-filtered field maps by a simple function that is the Fourier tra...

journal_title：Magnetic resonance in medicine

authors： Wharton S,Schäfer A,Bowtell R

更新日期：2010-05-01 00:00:00

abstract：:The investigation of flow behavior in coronary arteries is of great importance for an understanding of heart failure and heart regulation mechanisms. The purpose of the present study was to demonstrate that flow velocity can be quantified in the coronary arteries of the isolated rat heart with high-resolution phase co...

journal_title：Magnetic resonance in medicine

authors： Köhler S,Hiller KH,Jakob PM,Bauer WR,Haase A

更新日期：2003-09-01 00:00:00

abstract：:Problems with in vivo proton spectroscopy include strong water and lipid signals, and the very complicated structures of the spectra. Multiple-quantum experiments can be designed to overcome these difficulties. Using a volume selective refocusing technique, one can demonstrate how multiple-quantum experiments can be p...

journal_title：Magnetic resonance in medicine

authors： McKinnon GC,Bosiger P

更新日期：1988-03-01 00:00:00

abstract：:Proton-electron double-resonance imaging (PEDRI) was used to assess renal function by monitoring the flow of the exogenous nitroxide free radical proxyl carboxylic acid (PCA) through normal and injured kidneys in the living rat. Kidney damage was induced by treatment with 2-bromoethylamine (BEA), which provides a well...

journal_title：Magnetic resonance in medicine

authors： Seimenis I,Foster MA,Lurie DJ,Hutchison JM,Whiting PH,Payne S

更新日期：1998-08-01 00:00:00

abstract：PURPOSE:To propose an explicit Balanced steady-state free precession (bSSFP) signal model that predicts eddy current-induced steady-state disruptions and to provide a prospective, practical, and general eddy current compensation method. THEORY AND METHODS:Gradient impulse response functions (GIRF) were used to simulat...

journal_title：Magnetic resonance in medicine

authors： Bruijnen T,Stemkens B,van den Berg CAT,Tijssen RHN

更新日期：2020-07-01 00:00:00

abstract：:Phase-contrast MRI can provide high-resolution angiographic velocity images, especially in conjunction with non-Cartesian k-space sampling. However, acquisitions can be sensitive to errors from artifacts from main magnetic field inhomogeneities and chemical shift from fat. Particularly in body imaging, fat content can...

journal_title：Magnetic resonance in medicine

authors： Johnson KM,Wieben O,Samsonov AA

更新日期：2010-06-01 00:00:00

abstract：:Myocardial blood flow varies during the cardiac cycle in response to pulsatile changes in epicardial circulation and cyclical variation in myocardial tension. First-pass assessment of myocardial perfusion by dynamic contrast-enhanced MRI is one of the most challenging applications of MRI because of the spatial and tem...

journal_title：Magnetic resonance in medicine

authors： Radjenovic A,Biglands JD,Larghat A,Ridgway JP,Ball SG,Greenwood JP,Jerosch-Herold M,Plein S

更新日期：2010-12-01 00:00:00

abstract：:In radiotherapy, target tissues are defined best on MR images due to their superior soft tissue contrast. Computed tomography imaging is geometrically accurate and it is needed for dose calculation and generation of reference images for treatment localization. Co-registration errors between MR and computed tomography ...

journal_title：Magnetic resonance in medicine

authors： Kapanen M,Collan J,Beule A,Seppälä T,Saarilahti K,Tenhunen M

更新日期：2013-07-01 00:00:00

abstract：:Noninvasive investigation of aldose reductase activities in rat testis was performed using 3-fluoro-3-deoxy-D-glucose (3-FDG) and nuclear magnetic resonance (NMR) spectroscopy/imaging. Quantitative determination of testis aldose reductase activities, expressed as the sorbitol index, showed a value similar to that of b...

journal_title：Magnetic resonance in medicine

authors： Nakada T,Kwee IL

更新日期：1993-04-01 00:00:00

abstract：:In this study, we report the use of a novel ultrashort echo time T(1)rhoT(1) sequence that combines a spin-lock preparation pulse with a two-dimensional ultrashort echo time sequence of a nominal echo time 8 microsec. The ultrashort echo time-T(1)rho sequence was employed to quantify T(1)rho in short T(2) tissues incl...

journal_title：Magnetic resonance in medicine

authors： Du J,Carl M,Diaz E,Takahashi A,Han E,Szeverenyi NM,Chung CB,Bydder GM

更新日期：2010-09-01 00:00:00

abstract：:Proton T(1rho)-dispersion MRI is demonstrated for indirect, in vivo detection of (17)O in the brain. This technique, which may be readily implemented on any clinical MRI scanner, is applied towards high-resolution, quantitative mapping of cerebral blood flow (CBF) in the rat by monitoring the clearance of (17)O-enrich...

journal_title：Magnetic resonance in medicine

authors： Tailor DR,Roy A,Regatte RR,Charagundla SR,McLaughlin AC,Leigh JS,Reddy R

更新日期：2003-03-01 00:00:00

abstract：:Cell death by apoptosis is critical in myocardial diseases, and noninvasive detection of early, reversible apoptosis might be useful clinically. Exogenous Annexin-V (ANX) protein binds membrane phosphatidylserine, which is externalized in early apoptosis. A molecular MRI probe was constructed with superparamagnetic ir...

journal_title：Magnetic resonance in medicine

authors： Dash R,Chung J,Chan T,Yamada M,Barral J,Nishimura D,Yang PC,Simpson PC

更新日期：2011-10-01 00:00:00

abstract：:A method for collecting MRI data on a set of rotated trajectories that begin at the center of k-space is outlined. It is theoretically slightly faster, slightly less susceptible to off-resonance and motion-induced phase, and produces images with slightly better signal-to-noise ratio than methods using Archimedean spir...

journal_title：Magnetic resonance in medicine

authors： Pipe JG

更新日期：1999-10-01 00:00:00

abstract：:Leakage of Gd-DTPA through a defective blood-brain barrier is measured quantitatively using dynamic MRI scanning, in which repeated scans are made after a bolus injection. Image registration artifacts are minimized; a dose of 0.1 mM/kg and an IR sequence enable enhancement to be measured quantitatively. The triexponen...

journal_title：Magnetic resonance in medicine

authors： Tofts PS,Kermode AG

更新日期：1991-02-01 00:00:00

abstract：PURPOSE:Direct mapping of neuronal currents using MRI would have fundamental impacts on brain functional imaging. Previous reports indicated that the stimulus-induced rotary saturation (SIRS) mechanism had the best potential of direct detection of neural oscillations; however, it lacked the high-sensitivity level neede...

journal_title：Magnetic resonance in medicine

authors： Jiang X,Sheng J,Li H,Chai Y,Zhou X,Wu B,Guo X,Gao JH

更新日期：2016-02-01 00:00:00

abstract：:An arterial spin labeling technique using separate RF labeling and imaging coils was used to obtain multislice perfusion images of the human brain at 3 T. Continuous RF irradiation at a peak power of 0.3 W was applied to the carotid arteries to adiabatically invert spins. Labeling was achieved without producing magnet...

journal_title：Magnetic resonance in medicine

authors： Zaharchuk G,Ledden PJ,Kwong KK,Reese TG,Rosen BR,Wald LL

更新日期：1999-06-01 00:00:00

abstract：:Proton magnetic resonance spectroscopy ((1)H MRS) was used to determine brain temperature in healthy volunteers. Partially water-suppressed (1)H MRS data sets were acquired at 3T from four different gray matter (GM)/white matter (WM) volumes. Brain temperatures were determined from the chemical-shift difference betwee...

journal_title：Magnetic resonance in medicine

authors： Childs C,Hiltunen Y,Vidyasagar R,Kauppinen RA

更新日期：2007-01-01 00:00:00

abstract：:Optimal control theory has been applied in the past for the design of RF pulses for selective excitation. This was the outcome of having established the controllability of the MR spin system for the selective excitation problem. "Minimum distance" was the main formulation used for the solution. Because of their robust...

journal_title：Magnetic resonance in medicine

authors： Rosenfeld D,Zur Y

更新日期：1996-09-01 00:00:00

abstract：:The pulse wave velocity (PWV) of aortic blood flow is considered a surrogate for aortic compliance. A new method using phase-contrast (PC)-MRI is presented whereby the spatial and temporal profiles of axial velocity along the descending aorta can be analyzed. Seventeen young healthy volunteers (the YH group), six olde...

journal_title：Magnetic resonance in medicine

authors： Yu HY,Peng HH,Wang JL,Wen CY,Tseng WY

更新日期：2006-10-01 00:00:00

abstract：:Phase-sensitive inversion-recovery (PSIR) imaging may provide enhanced T(1) contrast. However, clinical implementation of PSIR imaging is hindered because image reconstruction with this method often lacks robustness and requires manual intervention, particularly for data acquired in multiple slices and with phased-arr...

journal_title：Magnetic resonance in medicine

authors： Ma J

更新日期：2005-04-01 00:00:00

abstract：:Volume-localized proton NMR spectroscopy was used to estimate bone marrow cellularity in the posterior iliac crests of patients undergoing treatment with hematopoietic growth factors for a variety of hematologic and neoplastic disorders. Twelve patients were accrued, six of whom were studied more than once, yielding a...

journal_title：Magnetic resonance in medicine

authors： Ballon D,Jakubowski A,Gabrilove J,Graham MC,Zakowski M,Sheridan C,Koutcher JA

更新日期：1991-05-01 00:00:00

abstract：:For clinical 31P MR spectroscopic imaging (MRSI) studies, where signal averaging is necessary, some improvement of sensitivity and spatial response function may be achieved by acquiring data over a spherical k-space volume and varying the number of averages acquired in proportion to the desired spatial filter. Eight d...

journal_title：Magnetic resonance in medicine

authors： Hugg JW,Maudsley AA,Weiner MW,Matson GB

更新日期：1996-09-01 00:00:00

abstract：:AFI (actual flip angle imaging) represents an interesting approach to map the B(1) transmit fields by measuring the spatial variations of the effective flip angle. However, the accuracy of the technique relies on the adequate spoiling of transverse magnetization. In the present work configuration theory was employed t...

journal_title：Magnetic resonance in medicine

authors： Nehrke K

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:Diffusion-weighted magnetic resonance imaging suffers from physiological noise, such as artifacts caused by motion or system instabilities. Therefore, there is a need for robust diffusion parameter estimation techniques. In the past, several techniques have been proposed, including RESTORE and iRESTORE (Chang e...

journal_title：Magnetic resonance in medicine

authors： Collier Q,Veraart J,Jeurissen B,den Dekker AJ,Sijbers J

更新日期：2015-06-01 00:00:00

abstract：:The suppression of water signals in in vivo proton spectra by means of multiple-quantum filtering can be brought about in several ways. This communication exposes the shortcomings of using purely subtractive filtering techniques to observe signals from metabolites that contain proton couplings of the form AX3. ...

journal_title：Magnetic resonance in medicine

authors： Nosel W,Trimble LA,Shen JF,Allen PS

更新日期：1989-09-01 00:00:00

abstract：:Dynamic contrast-enhanced MRI using gadolinium or manganese provides unique characterization of myocardium and its pathology. In this study, an electrocardiography (ECG) triggered saturation recovery Look-Locker method was developed and validated for fast cardiac T(1) mapping in small animal models. By sampling the in...

journal_title：Magnetic resonance in medicine

authors： Li W,Griswold M,Yu X

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:To develop a modular magnetization preparation sequence for combined T2 -preparation and multidimensional outer volume suppression (OVS) for coronary artery imaging. METHODS:A combined T2 -prepared 1D OVS sequence with fat saturation was defined to contain a 90°-60 180°60 composite nonselective tip-down pulse,...

journal_title：Magnetic resonance in medicine

authors： Zeng DY,Baron CA,Malavé MO,Kerr AB,Yang PC,Hu BS,Nishimura DG

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:Magnetically labeled cells and tissue iron deposits provide qualitative means to detect and monitor cardiovascular and cerebrovascular diseases with magnetic resonance imaging. However, to quantitatively examine the extent of pathological micromorphological changes, detailed knowledge about microstructural para...

journal_title：Magnetic resonance in medicine

authors： Kurz FT,Kampf T,Heiland S,Bendszus M,Schlemmer HP,Ziener CH

更新日期：2014-05-01 00:00:00