Abstract:
:The investigation of flow behavior in coronary arteries is of great importance for an understanding of heart failure and heart regulation mechanisms. The purpose of the present study was to demonstrate that flow velocity can be quantified in the coronary arteries of the isolated rat heart with high-resolution phase contrast MRI. A phase contrast cine-FLASH imaging sequence was used for flow quantification with an in-plane resolution of 70 microm and a slice thickness of 500 microm. With time-resolved measurements, coronary flow over the heart cycle was analyzed. Furthermore, the flow behavior in coronary stenosis was investigated and the degree of stenosis was quantified with MR phase contrast imaging. To achieve the required spatial resolution and a satisfactory signal-to-noise ratio, the experiments were performed at 11.75 T.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Köhler S,Hiller KH,Jakob PM,Bauer WR,Haase Adoi
10.1002/mrm.10563subject
Has Abstractpub_date
2003-09-01 00:00:00pages
449-52issue
3eissn
0740-3194issn
1522-2594journal_volume
50pub_type
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journal_title:Magnetic resonance in medicine
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