Noninvasive analysis of aldose reductase activities in rat testis: 3-FDG NMR spectroscopy and imaging.

Abstract:

:Noninvasive investigation of aldose reductase activities in rat testis was performed using 3-fluoro-3-deoxy-D-glucose (3-FDG) and nuclear magnetic resonance (NMR) spectroscopy/imaging. Quantitative determination of testis aldose reductase activities, expressed as the sorbitol index, showed a value similar to that of brain. Sorbitol imaging demonstrated aldose reductase activities in testis to be confined primarily to the central region of this organ. The 3-FDG 19F NMR method appears to have clinical potential in the evaluation of testicular function, especially that of spermatogenesis, noninvasively.

journal_name

Magn Reson Med

authors

Nakada T,Kwee IL

doi

10.1002/mrm.1910290417

subject

Has Abstract

pub_date

1993-04-01 00:00:00

pages

543-5

issue

4

eissn

0740-3194

issn

1522-2594

journal_volume

29

pub_type

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