Sensitivity regularization of the Cramér-Rao lower bound to minimize B1 nonuniformity effects in quantitative magnetization transfer imaging.

abstract：:In this work, substrate selection was monitored in the left ventricle of the canine myocardium by following pyruvate and lactate oxidation under in vivo conditions at basal and elevated workloads. These studies were conducted in the open chest model using dynamic 13C NMR techniques in the presence and absence of dichl...

journal_title：Magnetic resonance in medicine

authors： Rath DP,Zhu H,Tong X,Jiang Z,Hamlin RL,Robitaille PM

更新日期：1997-12-01 00:00:00

abstract：:The proton exchange rates between water and the hydroxyl protons of threonine, serine, tyrosine, the amino protons of lysine, and the guanidinium protons of arginine were measured in the pH range 0.5 to 8.5 and for the temperatures 4 degrees C, 10 degrees C, 20 degrees C, 30 degrees C, and 36 degrees C. The intrinsic ...

journal_title：Magnetic resonance in medicine

authors： Liepinsh E,Otting G

更新日期：1996-01-01 00:00:00

abstract：:A new NMR imaging technique, aiming at a reduction of the data acquisition time, is described in detail. The method is applicable in all multidimensional imaging situations where at least one spatial coordinate is resolved. Discussed at some length are the point-spread function, the required bandwidth of the NMR spect...

journal_title：Magnetic resonance in medicine

authors： van Uijen CM,den Boef JH,Verschuren FJ

更新日期：1985-06-01 00:00:00

abstract：:Magnetization transfer experiments using an off-resonance irradiation technique were performed on bovine serum albumin solutions by varying the irradiation frequency and the concentration. A transition of the magnetization transfer spectrum from Lorentzian to Gaussian line shape was observed around the critical concen...

journal_title：Magnetic resonance in medicine

authors： Iino M

更新日期：1994-10-01 00:00:00

abstract：:In vivo echo-planar MR imaging was used to measure apparent diffusion coefficients (ADC) of cerebral tissues in a comprehensive noninvasive evaluation of early ischemic brain damage induced by occlusion of the middle cerebral artery (MCA) in a cat model of acute regional stroke. Within 10 min after arterial occlusion,...

journal_title：Magnetic resonance in medicine

authors： Kucharczyk J,Mintorovitch J,Asgari HS,Moseley M

更新日期：1991-06-01 00:00:00

abstract：PURPOSE:Chemical exchange saturation transfer (CEST) MRI has shown promise in tissue characterization in diseases like stroke and tumor. However, in vivo CEST imaging such as amide proton transfer (APT) MRI is challenging because of concomitant factors such as direct water saturation, macromolecular magnetization trans...

journal_title：Magnetic resonance in medicine

authors： Yuwen Zhou I,Wang E,Cheung JS,Lu D,Ji Y,Zhang X,Fulci G,Sun PZ

更新日期：2017-12-01 00:00:00

abstract：:A single-shot, two-echo method for the simultaneous detection of multiple-quantum (MQ)-filtered gamma-aminobutyric acid (GABA) and creatine (Cr) was developed and demonstrated in the human brain in vivo at 3 Tesla. The simultaneously measured Cr singlet served as a navigator for the spectral phase of GABA and any freq...

journal_title：Magnetic resonance in medicine

authors： Choi IY,Lee SP,Merkle H,Shen J

更新日期：2004-06-01 00:00:00

abstract：:In the dynamic nuclear polarization process, microwave irradiation facilitates exchange of polarization from a radical's unpaired electron to nuclear spins at cryogenic temperatures, increasing polarization by >10,000. Doping samples with Gd(3+) ions further increases the achievable solid-state polarization. However, ...

journal_title：Magnetic resonance in medicine

authors： Gordon JW,Fain SB,Rowland IJ

更新日期：2012-12-01 00:00:00

abstract：:A lactate editing sequence based on the use of spin-locking pulses with surface coils is described. The sequence retains more than 90% of the available lactate magnetization and suppresses at least 95% of the lipid signal in a single scan and ca. 99.5% after a simple two step cycle. The technique allows simultaneous o...

journal_title：Magnetic resonance in medicine

authors： Bourgeois D,Kozlowski P

更新日期：1993-03-01 00:00:00

abstract：PURPOSE:Image-guided prostate biopsies are routinely acquired in the diagnosis and treatment monitoring of prostate cancer, yielding useful tissue for identifying metabolic biomarkers and therapeutic targets. We developed an optimized biopsy tissue culture protocol in combination with [1,6-13 C2 ]glucose labeling and q...

journal_title：Magnetic resonance in medicine

authors： Bancroft Brown J,Sriram R,VanCriekinge M,Delos Santos R,Sun J,Delos Santos J,Tabatabai ZL,Shinohara K,Nguyen H,Peehl DM,Kurhanewicz J

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:To develop a semiautomatic method for rapid segmentation of myocardial tissue phase mapping (TPM) data. METHODS:Manual segmentation of the myocardium was performed at end-diastole and end-systole. The points in both user-defined masks were then automatically tracked over the entire cardiac cycle using temporal...

journal_title：Magnetic resonance in medicine

authors： Espe EKS,Skårdal K,Aronsen JM,Zhang L,Sjaastad I

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:Despite the increasing understanding of major depressive disorder (MDD) using neuroimaging techniques, the topological organization of anatomical networks underlying MDD remains unclear. METHODS:The topological organization of brain anatomical networks was explored using complex network approaches. Diffusion t...

journal_title：Magnetic resonance in medicine

authors： Qin J,Wei M,Liu H,Yan R,Luo G,Yao Z,Lu Q

更新日期：2014-11-01 00:00:00

abstract：:Advances in modern magnetic resonance imaging (MRI) pulse sequences have enabled clinically practical cortical bone imaging. Human cortical bone is known to contain a distribution of T(1) and T(2) components attributed to bound and pore water, although clinical imaging approaches have yet to discriminate bound from po...

journal_title：Magnetic resonance in medicine

authors： Horch RA,Gochberg DF,Nyman JS,Does MD

更新日期：2012-12-01 00:00:00

abstract：:Chemical shift-based multipoint water-fat separation methods have been applied in balanced steady-state free precession (bSSFP) sequences because of the high signal-to-noise-ratio (SNR) attainable. In this approach the echo formation is approximated to occur concurrently for both water and fat at an echo time (TE) equ...

journal_title：Magnetic resonance in medicine

authors： Kim H,Pinus AB,Wang J,Murphy PS,Constable RT

更新日期：2007-08-01 00:00:00

abstract：:The regional cerebral blood flow (rCBF) values determined using continuous arterial spin labeling (CASL) are subject to several sources of variability, including natural physiologic variations, sensitivity to the input parameters, and the use of different quantification models. To date, a thorough analysis of the impa...

journal_title：Magnetic resonance in medicine

authors： Steger TR,White RA,Jackson EF

更新日期：2005-04-01 00:00:00

abstract：:MR images acquired by using an arterial spin-labeling technique showed spatial and temporal variations of perfusion in the skeletal muscle of exercising humans. Perfusion measurements made during plantar flexion exercise in normal volunteers were consistent with those obtained by traditional techniques reported in the...

journal_title：Magnetic resonance in medicine

authors： Frank LR,Wong EC,Haseler LJ,Buxton RB

更新日期：1999-08-01 00:00:00

abstract：PURPOSE:Simultaneous brain and spinal cord functional MRI is emerging as a new tool to study the central nervous system but is challenging. Poor B0 homogeneity and small size of the spinal cord are principal obstacles to this nascent technology. Here we extend a dynamic shimming approach, first posed by Finsterbusch, b...

journal_title：Magnetic resonance in medicine

authors： Islam H,Law CSW,Weber KA,Mackey SC,Glover GH

更新日期：2019-02-01 00:00:00

abstract：:Magnetic resonance imaging measurements of the apparent rate of water diffusion in tumors are sensitive to variations in tissue cellularity, which have been shown useful for characterizing tumors and their responses to treatments. However, because of technical limitations on most MRI systems, conventional pulse gradie...

journal_title：Magnetic resonance in medicine

authors： Xu J,Does MD,Gore JC

更新日期：2009-04-01 00:00:00

abstract：:In order to determine if an increase in myocardial oxygen consumption is accompanied by changes in high energy phosphates in normal subjects and patients with dilated cardiomyopathy, phosphorus-31 spectra were acquired under resting conditions and during dobutamine infusion. In seven normal subjects, dobutamine raised...

journal_title：Magnetic resonance in medicine

authors： Schaefer S,Schwartz GG,Steinman SK,Meyerhoff DJ,Massie BM,Weiner MW

更新日期：1992-06-01 00:00:00

abstract：PURPOSE:Endothelial nitric oxide synthase (eNOS) plays a central role in regulating vascular tone, blood flow, and microvascular permeability. Endothelial dysfunction, including eNOS dysfunction, is an early biomarker of vascular disease. This study aimed to show that myocardial T1 mapping during nitric oxide synthase ...

journal_title：Magnetic resonance in medicine

authors： Cui SX,Epstein FH

更新日期：2018-04-01 00:00:00

abstract：:Dynamic susceptibility contrast (DSC) MRI is now increasingly used for measuring perfusion in many different applications. The quantification of DSC data requires the measurement of the arterial input function (AIF) and the deconvolution of the tissue concentration time curve. One of the most accepted deconvolution me...

journal_title：Magnetic resonance in medicine

authors： Calamante F,Gadian DG,Connelly A

更新日期：2000-09-01 00:00:00

abstract：:31P NMR spectroscopy was used to study renal allografts in rats subjected to allograft rejection, cyclosporine toxicity, ischemia, and ureteral obstruction. Parameters of relative peak areas and intracellular pH were accurately distinguished among the different causes of graft dysfunction. Ureteral obstruction was cle...

journal_title：Magnetic resonance in medicine

authors： Shapiro JI,Haug CE,Weil R 3rd,Chan L

更新日期：1987-10-01 00:00:00

abstract：PURPOSE:The goal of this study is to characterize and improve the accuracy of 2D magnetic resonance fingerprinting (MRF) scans in the presence of slice profile (SP) and B1 imperfections, which are two main factors that affect quantitative results in MRF. METHODS:The SP and B1 imperfections are characterized and correc...

journal_title：Magnetic resonance in medicine

authors： Ma D,Coppo S,Chen Y,McGivney DF,Jiang Y,Pahwa S,Gulani V,Griswold MA

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:Cardiac stimulation (CS) limits to gradient coil switching speed are difficult to measure in humans; instead, current regulatory guidelines (IEC 60601-2-33) are based on animal experiments and electric field-to-dB/dt conversion factors computed for a simple, homogeneous body model. We propose improvement to thi...

journal_title：Magnetic resonance in medicine

authors： Klein V,Davids M,Schad LR,Wald LL,Guérin B

更新日期：2021-02-01 00:00:00

abstract：PURPOSE:The primary purpose of this study is to propose a method for the simultaneous quantitative three-dimensional (3D) mapping of conductivity and susceptibility using double-echo ultrashort echo time (UTE) imaging. The secondary purpose is to investigate the changes of these properties over time during in vitro hem...

journal_title：Magnetic resonance in medicine

authors： Gho SM,Shin J,Kim MO,Kim DH

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:To develop and evaluate a neural network-based method for Gibbs artifact and noise removal. METHODS:A convolutional neural network (CNN) was designed for artifact removal in diffusion-weighted imaging data. Two implementations were considered: one for magnitude images and one for complex images. Both models we...

journal_title：Magnetic resonance in medicine

authors： Muckley MJ,Ades-Aron B,Papaioannou A,Lemberskiy G,Solomon E,Lui YW,Sodickson DK,Fieremans E,Novikov DS,Knoll F

更新日期：2021-01-01 00:00:00

abstract：PURPOSE:To develop and validate a method for choosing the optimal two-dimensional CAIPIRINHA kernel for subtraction contrast-enhanced MR angiography (CE-MRA) and estimate the degree of image quality improvement versus that of some reference acceleration parameter set at R ≥ 8. METHODS:A metric based on patient-specifi...

journal_title：Magnetic resonance in medicine

authors： Weavers PT,Borisch EA,Riederer SJ

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:Subendocardial dark-rim artifacts (DRAs) remain a major concern in first-pass perfusion (FPP) myocardial MRI and may lower the diagnostic accuracy for detection of ischemia. A major source of DRAs is the "Gibbs ringing" effect. We propose an optimized radial acquisition strategy aimed at eliminating ringing-ind...

journal_title：Magnetic resonance in medicine

authors： Sharif B,Dharmakumar R,LaBounty T,Arsanjani R,Shufelt C,Thomson L,Merz CN,Berman DS,Li D

更新日期：2014-07-01 00:00:00

abstract：:Susceptibility artifacts and transmission radio frequency (RF) field (B(1) +) inhomogeneity are major limitations in high-field gradient echo MRI. Previously proposed numerical 2D spectral-spatial RF pulses have been shown to be promising for reducing the through-plane signal loss susceptibility artifact by incorporat...

journal_title：Magnetic resonance in medicine

authors： Yang C,Deng W,Stenger VA

更新日期：2011-02-01 00:00:00

abstract：:SENSE reconstruction suffers from an ill-conditioning problem, which increasingly lowers the signal-to-noise ratio (SNR) as the reduction factor increases. Ill-conditioning also degrades the convergence behavior of iterative conjugate gradient reconstructions for arbitrary trajectories. Regularization techniques are o...

journal_title：Magnetic resonance in medicine

authors： Ying L,Liu B,Steckner MC,Wu G,Wu M,Li SJ

更新日期：2008-08-01 00:00:00