Abstract:
:In vivo echo-planar MR imaging was used to measure apparent diffusion coefficients (ADC) of cerebral tissues in a comprehensive noninvasive evaluation of early ischemic brain damage induced by occlusion of the middle cerebral artery (MCA) in a cat model of acute regional stroke. Within 10 min after arterial occlusion, ADC was significantly lower in tissues within the vascular territory of the occluded MCA than in normally perfused tissues in the contralateral hemisphere. Sequential echo-planar imaging was then used in conjunction with bolus injections of the magnetic susceptibility contrast agent, dysprosium DTPA-BMA, to characterize the underlying cerebrovascular perfusion deficits. Normally perfused regions of brain were identified by a dose-dependent 35-70% loss of signal intensity within 6-8 s of contrast administration, whereas ischemic regions appeared relatively hyperintense. These data indicate that sequential diffusion/perfusion imaging may be useful in differentiating permanently damaged from reversibly ischemic brain tissue.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Kucharczyk J,Mintorovitch J,Asgari HS,Moseley Mdoi
10.1002/mrm.1910190220subject
Has Abstractpub_date
1991-06-01 00:00:00pages
311-5issue
2eissn
0740-3194issn
1522-2594journal_volume
19pub_type
杂志文章abstract:PURPOSE:To develop a flexible fast spin echo (FSE) triple-echo Dixon (FTED) technique. METHODS:An FSE pulse sequence was modified by replacing each readout gradient with three fast-switching bipolar readout gradients with minimal interecho dead time. The corresponding three echoes were used to generate three raw image...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.26186
更新日期:2017-03-01 00:00:00
abstract::A method is presented for measuring myocardial deformation in a breath-hold with tagged cine MRI. Tagged cine images of human hearts are obtained in arbitrary oblique planes on a standard imager with as few as four heartbeats. The scan time has been reduced 16- to 64-fold from previous techniques. ...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.1910280214
更新日期:1992-12-01 00:00:00
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journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25147
更新日期:2015-02-01 00:00:00
abstract::A common type of motion present in clinical magnetic resonance imaging examinations is rotational motion, such as that due to voluntary motion during head examinations. The correction scheme presented in this work offers a method for eliminating the effects of rotations within the imaging plane. Integral to the implem...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.1910330511
更新日期:1995-05-01 00:00:00
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journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
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更新日期:2019-08-01 00:00:00
abstract:PURPOSE:Diffusion magnetic resonance imaging (MRI) microstructure imaging provides a unique noninvasive probe into tissue microstructure. The technique relies on biophysically motivated mathematical models, relating microscopic tissue features to the magnetic resonance (MR) signal. This work aims to determine which com...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.25080
更新日期:2014-12-01 00:00:00
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journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.21925
更新日期:2009-04-01 00:00:00
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journal_title:Magnetic resonance in medicine
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更新日期:2000-03-01 00:00:00
abstract:PURPOSE:The goal of this work was to detect disease-related microstructural changes to the liver using magnetic resonance imaging. Chronic liver disease can cause microstructural changes in the liver that reduce plasma access to the perisinusoidal space--the site of exchange between the blood plasma and the hepatic par...
journal_title:Magnetic resonance in medicine
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更新日期:2013-12-01 00:00:00
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journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.28425
更新日期:2021-01-01 00:00:00
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更新日期:2010-07-01 00:00:00
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journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.25278
更新日期:2015-04-01 00:00:00
abstract::MR techniques have proven their ability to investigate skeletal muscle function in situ. Their benefit in terms of noninvasiveness is, however, lost in animal research, given that muscle stimulation and force output measurements are usually achieved using invasive surgical procedures, thereby excluding repeated invest...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.22386
更新日期:2010-07-01 00:00:00
abstract::The focal underdetermined system solver (FOCUSS) was originally designed to obtain sparse solutions by successively solving quadratic optimization problems. This article adapts FOCUSS for a projection reconstruction MR imaging problem to obtain high resolution reconstructions from angular under-sampled radial k-space ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21202
更新日期:2007-04-01 00:00:00
abstract::Accurate quantification of myocardial perfusion remains challenging due to saturation of the arterial input function at high contrast concentrations. A method for estimating the arterial input function directly from tissue curves in the myocardium that avoids these difficulties is presented. In this constrained altern...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22809
更新日期:2011-08-01 00:00:00
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journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21115
更新日期:2007-02-01 00:00:00
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journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22163
更新日期:2009-12-01 00:00:00
abstract::Any number of coils can in principle be used simultaneously and independently in magnetic resonance imaging if the mutual inductances are sufficiently small. Surface coils and head or body coils have equal sensitivity at some crossover depth of the order of 6 to 10 cm. Using a 7.5-cm-diameter surface coil that was int...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910060212
更新日期:1988-02-01 00:00:00
abstract::Knowledge about the triglyceride (fat) (1)H spectrum enables quantitative determination of several triglyceride characteristics. This work describes a model-based chemical shift imaging method that separates water and fat signal and provides maps of three triglyceride quantities: fatty acid carbon chain length, unsatu...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.24196
更新日期:2012-12-01 00:00:00
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更新日期:2004-02-01 00:00:00
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更新日期:2021-02-01 00:00:00
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更新日期:1994-09-01 00:00:00
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更新日期:2018-04-01 00:00:00
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journal_title:Magnetic resonance in medicine
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更新日期:2004-04-01 00:00:00
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journal_title:Magnetic resonance in medicine
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更新日期:1996-10-01 00:00:00
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journal_title:Magnetic resonance in medicine
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更新日期:2019-08-01 00:00:00
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journal_title:Magnetic resonance in medicine
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更新日期:2021-01-01 00:00:00
abstract::Longitudinal P-31 relaxation rate enhancements of phosphate groups have been measured at pH 7-7.2 and 310 degrees K on aqueous solutions containing adenosine triphosphate (ATP), phosphocreatine (PCr), inorganic phosphate (Pi) and some lanthanide complexes (Gd-DOTA, Gd-HPDO3A, Gd-DO3A, Gd-DTPA, Gd-DTPA-BMA). The macroc...
journal_title:Magnetic resonance in medicine
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更新日期:1994-04-01 00:00:00
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更新日期:2014-03-01 00:00:00
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更新日期:2019-06-01 00:00:00