Single-shot two-echo technique for simultaneous measurement of GABA and creatine in the human brain in vivo.

abstract：:Experimental procedures for obtaining localized 31P NMR spectra of humans by means of the ISIS sequence are discussed in detail. The technique is optimized for use with volume coils and with surface coils in order to measure localized 31P NMR spectra of different tissues and organs. Selective frequency-modulated (FM) ...

journal_title：Magnetic resonance in medicine

authors： Luyten PR,Groen JP,Vermeulen JW,den Hollander JA

更新日期：1989-07-01 00:00:00

abstract：:The ultra-fast application of the RARE experiment is described in detail, with special emphasis on its multifarious applications with preparation experiments that produce transverse magnetization. The factors affecting the temporal evolution of the magnetization during the experiment are described, and the implication...

journal_title：Magnetic resonance in medicine

authors： Norris DG,Börnert P,Reese T,Leibfritz D

更新日期：1992-09-01 00:00:00

abstract：:Phase contrast flow velocity measurements were performed in six healthy volunteers and 30 patients with arteriosclerotic disease. The iliac arteries were investigated in 8 cases and the femoral arteries in 28 cases. In the first 24 patients, 16 evenly distributed data sets were acquired during one cardiac cycle. In th...

journal_title：Magnetic resonance in medicine

authors： Krug B,Kugel H,Harnischmacher U,Heindel W,Schmidt R,Krings F

更新日期：1995-11-01 00:00:00

abstract：:Calibration of the spatial sensitivity functions of coil arrays is a crucial element in parallel magnetic resonance imaging (PMRI). The most common approach has been to measure coil sensitivities directly using one or more low-resolution images acquired before or after accelerated data acquisition. However, since it i...

journal_title：Magnetic resonance in medicine

authors： McKenzie CA,Yeh EN,Ohliger MA,Price MD,Sodickson DK

更新日期：2002-03-01 00:00:00

abstract：:Kinetic analysis with mathematical models has become increasingly important to quantify physiological parameters in computed tomography (CT), positron emission tomography (PET), and dynamic contrast-enhanced MRI (DCE-MRI). The modified Kety/Tofts model and the graphical (Patlak) model have been widely applied to DCE-M...

journal_title：Magnetic resonance in medicine

authors： Chen H,Li F,Zhao X,Yuan C,Rutt B,Kerwin WS

更新日期：2011-09-01 00:00:00

abstract：:Diffusion tensor imaging has been used in a number of spinal cord studies, but severe distortions caused by susceptibility induced field inhomogeneities limit its applicability to investigate small volumes within acceptable acquisition times. A way to evaluate image distortions is to map the point spread function of t...

journal_title：Magnetic resonance in medicine

authors： Lundell H,Barthelemy D,Biering-Sørensen F,Cohen-Adad J,Nielsen JB,Dyrby TB

更新日期：2013-01-01 00:00:00

abstract：:As the static magnetic field strength used in human magnetic resonance imaging increases, the wavelength of the corresponding radiofrequency field becomes comparable to the dimensions of the coil and volume of interest. The dielectric resonance effects that arise in this full wavelength regime may be partially compens...

journal_title：Magnetic resonance in medicine

authors： Pinkerton RG,Barberi EA,Menon RS

更新日期：2005-08-01 00:00:00

abstract：:Phase-contrast magnetic resonance imaging is subject to numerous sources of error, which decrease clinical confidence in the reported measures. This work outlines how stationary perivascular fat can impart a significant chemical shift induced phase-contrast magnetic resonance imaging measurement error using computatio...

journal_title：Magnetic resonance in medicine

authors： Middione MJ,Ennis DB

更新日期：2013-02-01 00:00:00

abstract：:A gradient coil design algorithm capable of controlling the position of the homogeneous region of interest (ROI) with respect to the current-carrying wires is required for many advanced imaging and spectroscopy applications. A modified minimum inductance target field method that allows the placement of a set of constr...

journal_title：Magnetic resonance in medicine

authors： Chronik BA,Rutt BK

更新日期：1998-02-01 00:00:00

abstract：:Stejskal and Tanner's ingenious pulsed field gradient design from 1965 has made diffusion NMR and MRI the mainstay of most studies seeking to resolve microstructural information in porous systems in general and biological systems in particular. Methods extending beyond Stejskal and Tanner's design, such as double diff...

journal_title：Magnetic resonance in medicine

authors： Shemesh N,Jespersen SN,Alexander DC,Cohen Y,Drobnjak I,Dyrby TB,Finsterbusch J,Koch MA,Kuder T,Laun F,Lawrenz M,Lundell H,Mitra PP,Nilsson M,Özarslan E,Topgaard D,Westin CF

更新日期：2016-01-01 00:00:00

abstract：:Baseline distortion in NMR spectroscopy, caused by the "dead time" between signal excitation and detection, makes quantitative interpretation difficult and is aesthetically displeasing. Here the use of the CLEAN algorithm for deconvolving the effect of signal dead time to produce a distortionless baseline is discussed...

journal_title：Magnetic resonance in medicine

authors： McKinnon GC,Burger C,Boesiger P

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:To demonstrate the feasibility of imaging a bolus of co-polarized [1-13 C]pyruvate and 13 C-urea to simultaneously assess both metabolism and perfusion in the rodent heart. METHODS:Copolarized [1-13 C]pyruvate and 13 C-urea was imaged using a multi-echo, flow-sensitized spiral pulse sequence. Healthy rats were...

journal_title：Magnetic resonance in medicine

authors： Lau AZ,Miller JJ,Robson MD,Tyler DJ

更新日期：2017-01-01 00:00:00

abstract：:Standard MRI cine exams for the study of cardiac function are segmented over several heartbeats and thus require a breath-hold to minimize breathing motion artifacts, which is a current limitation of this approach. The purpose of this study was to develop a method for the measurement and correction of respiratory moti...

journal_title：Magnetic resonance in medicine

authors： Leung AO,Paterson I,Thompson RB

更新日期：2008-09-01 00:00:00

abstract：:Wavelet packet analysis is a mathematical transformation that can be used to post-process images, for example, to remove image noise ("denoising"). At a very low signal-to-noise ratio (SNR <5), standard magnitude magnetic resonance images have skewed Rician noise statistics that degrade denoising performance. Since th...

journal_title：Magnetic resonance in medicine

authors： Wood JC,Johnson KM

更新日期：1999-03-01 00:00:00

abstract：PURPOSE:To investigate whether saturation using existing methods developed for 3T imaging is feasible for clinical perfusion imaging at 7T, and to propose a new design of saturation pulse train for first-pass myocardial perfusion imaging at 7T. METHODS:The new design of saturation pulse train consists of four hyperbol...

journal_title：Magnetic resonance in medicine

authors： Tao Y,Hess AT,Keith GA,Rodgers CT,Liu A,Francis JM,Neubauer S,Robson MD

更新日期：2015-04-01 00:00:00

abstract：:Brain water proton (1H2O) longitudinal relaxation time constants (T1) were obtained from three healthy individuals at magnetic field strengths (B0) of 0.2 Tesla (T), 1.0T, 1.5T, 4.0T, and 7.0T. A 5-mm midventricular axial slice was sampled using a modified Look-Locker technique with 1.5 mm in-plane resolution, and 32 ...

journal_title：Magnetic resonance in medicine

authors： Rooney WD,Johnson G,Li X,Cohen ER,Kim SG,Ugurbil K,Springer CS Jr

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:To study the utility of fractional calculus in modeling gradient-recalled echo MRI signal decay in the normal human brain. METHODS:We solved analytically the extended time-fractional Bloch equations resulting in five model parameters, namely, the amplitude, relaxation rate, order of the time-fractional derivat...

journal_title：Magnetic resonance in medicine

authors： Qin S,Liu F,Turner IW,Yu Q,Yang Q,Vegh V

更新日期：2017-04-01 00:00:00

abstract：:Using a 32-echo imaging pulse sequence, T2 relaxation decay curves were acquired from five white- and six gray-matter brain structures outlined in 12 normal volunteers. The water contents of white and gray matter were 0.71 (0.01) and 0.83 (0.03) g/ml, respectively. All white-matter structures had significantly higher ...

journal_title：Magnetic resonance in medicine

authors： Whittall KP,MacKay AL,Graeb DA,Nugent RA,Li DK,Paty DW

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:To use quantitative susceptibility mapping (QSM) to investigate changes in cartilage canals in the distal femur of juvenile goats after their surgical transection. METHODS:Chondronecrosis was surgically induced in the right medial femoral condyles of four 4-day-old goats. Both the operated and control knees we...

journal_title：Magnetic resonance in medicine

authors： Wang L,Nissi MJ,Toth F,Johnson CP,Garwood M,Carlson CS,Ellermann J

更新日期：2017-03-01 00:00:00

abstract：PURPOSE:To evaluate proton density fat fraction (PDFF) and R2* as markers of bone marrow composition and structure in inflamed bone in patients with spondyloarthritis. METHODS:Phantoms containing fat, water, and trabecular bone were constructed with proton density fat fraction (PDFF) and bone mineral density (BMD) val...

journal_title：Magnetic resonance in medicine

authors： Bray TJP,Bainbridge A,Punwani S,Ioannou Y,Hall-Craggs MA

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To investigate the heating induced by (pseudo)-continuous arterial spin labeling ((p)CASL) sequences in vivo at 9.4T and to evaluate the benefit of a dedicated labeling coil. METHODS:Temperature was measured continuously in the brain, neck, and rectum of 9 rats with fiber-optic temperature probes while running...

journal_title：Magnetic resonance in medicine

authors： Hirschler L,Collomb N,Voiron J,Köhler S,Barbier EL,Warnking JM

更新日期：2020-01-01 00:00:00

abstract：:We used high-field (13)C NMR (18.8 T) to assign unambiguously the isotopic shifts induced by the deuterium substitutions of the H3(proR) and H3(proS) hydrogens of (2-(13)C) glutamate in extracts of the brain from deuterated animals. Monodeuterated H3R or H3S glutamate diastereoisomers were produced stereospecifically ...

journal_title：Magnetic resonance in medicine

authors： Rodrigues TB,Violante IR,Cerdán S

更新日期：2010-04-01 00:00:00

abstract：:An improved double quantum coherence (DQC) filter for the selective in vivo detection of glutathione (GSH) in the human brain at 1.5 Tesla is presented. The goal was to minimize contamination of the DQC-filtered GSH signal at 2.9 ppm with contributions arising from GABA. The modification consists of tailoring the freq...

journal_title：Magnetic resonance in medicine

authors： Trabesinger AH,Boesiger P

更新日期：2001-04-01 00:00:00

abstract：:Direct measurement of neural currents by means of MRI can potentially open a high temporal resolution (10-100 ms) window applicable for monitoring dynamics of neuronal activity without loss of the high spatial resolution afforded by MRI. Previously, we have shown that the alternating balanced steady state imaging affo...

journal_title：Magnetic resonance in medicine

authors： Buračas GT,Jung Y,Lee J,Buxton RB,Wong EC,Liu TT

更新日期：2012-05-01 00:00:00

abstract：:A technique using hyperpolarized (HP) 3He to image the small airways of the lung by using moderate flip angles and a short scanning period during early inspiration is demonstrated. Flip angles (alpha) ranging from 10-90 degrees were used in guinea pig experiments with scanning during the entire inspiration period. A s...

journal_title：Magnetic resonance in medicine

authors： Chen XJ,Chawla MS,Hedlund LW,Möller HE,MacFall JR,Johnson GA

更新日期：1998-01-01 00:00:00

abstract：:A combined carbogen ultrasmall superparamagnetic iron oxide (USPIO) imaging protocol was developed and applied in vivo in two murine colorectal tumor xenograft models, HCT116 and SW1222, with established disparate vascular morphology, to investigate whether additional information could be extracted from the combinatio...

journal_title：Magnetic resonance in medicine

authors： Burrell JS,Walker-Samuel S,Baker LC,Boult JK,Ryan AJ,Waterton JC,Halliday J,Robinson SP

更新日期：2011-07-01 00:00:00

abstract：PURPOSE:To develop a method for retrospective artifact elimination of MRS data. This retrospective method was based on an approach that combines jackknife analyses with the correlation of spectral windows, and therefore termed "JKC." METHODS:Twelve healthy volunteers performed 3 separate measurement protocols using a ...

journal_title：Magnetic resonance in medicine

authors： Tapper S,Tisell A,Helms G,Lundberg P

更新日期：2019-04-01 00:00:00

abstract：:Gradient-echo EPI, blood oxygenation level-dependent (BOLD) functional MRI (fMRI) using parallel imaging (PI) is demonstrated at 7 Tesla with 16 channels, a fourfold 1D reduction factor (R), and fourfold maximal aliasing. The resultant activation detection in finger-tapping fMRI studies was robust, in full agreement w...

journal_title：Magnetic resonance in medicine

authors： Moeller S,Van de Moortele PF,Goerke U,Adriany G,Ugurbil K

更新日期：2006-07-01 00:00:00

abstract：:The prebolus technique allows one to quantify perfusion in the human heart with a low variability by means of MRI. In this study the prebolus technique was used to determine quantitative perfusion values in the human heart under adenosine stress and to measure the myocardial perfusion reserve (MPR). Twelve healthy vol...

journal_title：Magnetic resonance in medicine

authors： Ritter C,Brackertz A,Sandstede J,Beer M,Hahn D,Köstler H

更新日期：2006-10-01 00:00:00

abstract：PURPOSE:A direct method of imaging neural activity was simulated to determine typical signal sizes. METHODS:An active bidomain finite-element model was used to estimate approximate perturbations in MR phase data as a result of neural tissue activity, and when an external MR electrical impedance tomography imaging curr...

journal_title：Magnetic resonance in medicine

authors： Sadleir RJ,Fu F,Chauhan M

更新日期：2019-01-01 00:00:00