Abstract:
PURPOSE:Despite the increasing understanding of major depressive disorder (MDD) using neuroimaging techniques, the topological organization of anatomical networks underlying MDD remains unclear. METHODS:The topological organization of brain anatomical networks was explored using complex network approaches. Diffusion tensor image data of 29 MDD patients and 30 healthy controls were collected. Network metrics such as strength, efficiency, and centrality were computed after the construction of brain anatomical networks. Between-group differences and correlations with clinical measurements were further explored. RESULTS:Compared with the healthy controls, MDD patients exhibited widely damaged information interactions in both cognitive-emotional circuitry and frontoparietal circuitry. Moreover, the centralities in the right prefrontal cortex involving the right middle frontal gyrus and the right gyrus rectus were negatively correlated with the duration of disease. Additionally, the centrality in the right inferior frontal gyrus (triangular part) and the efficiency in the right superior frontal gyrus (orbital part) were both positively related to the depression severity. CONCLUSION:These findings suggest that altered connectivity involved in affective and cognitive processing procedures might contribute to the pathogenesis of MDD.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Qin J,Wei M,Liu H,Yan R,Luo G,Yao Z,Lu Qdoi
10.1002/mrm.25036subject
Has Abstractpub_date
2014-11-01 00:00:00pages
1397-407issue
5eissn
0740-3194issn
1522-2594journal_volume
72pub_type
杂志文章abstract::Quantitative estimation of T1 is a challenging but important task inherent to many clinical applications. The most commonly used paradigm for estimating T1 in vivo involves performing a sequence of spoiled gradient-recalled echo acquisitions at different flip angles, followed by fitting of an exponential model to the ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24401
更新日期:2013-06-01 00:00:00
abstract::In the present work, diffusion-weighted (DW)-NMR spectroscopy of glutamate was performed during a (13)C-labeled glucose infusion in monkey brain (six experiments). It is shown that glutamate (13)C labeling occurs significantly faster at higher diffusion weightings-slightly for glutamate in position C4, and more marked...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21661
更新日期:2008-08-01 00:00:00
abstract::The recently developed technique of gradient, high-resolution magic-angle spinning NMR (g-hr-MAS-NMR) spectroscopy was applied to the study of ex vivo human lipoma and liposarcoma tissue. Compared with conventional 1H-NMR, the g-hr-MAS method yielded a large improvement in spectral resolution and permitted the detecti...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910380307
更新日期:1997-09-01 00:00:00
abstract::Nanostructured hydrogels have been developed as synthetic tissues and scaffolds for cell and drug delivery, and as guides for tissue regeneration. A fundamental problem in the development of synthetic hydrogels is that implanted gel structure is difficult to monitor noninvasively. This work demonstrates that the aggre...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22570
更新日期:2010-12-01 00:00:00
abstract::Genetically engineered mouse models provide enormous potential for investigation of the underlying mechanisms of atherosclerotic disease, but noninvasive imaging methods for analysis of atherosclerosis in mice are currently limited. This study aimed to demonstrate the feasibility of MRI to noninvasively visualize athe...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10500
更新日期:2003-07-01 00:00:00
abstract:PURPOSE:Reference region models (RRMs) can quantify tumor perfusion in dynamic contrast-enhanced MRI without an arterial input function. Inspection of the RRM reveals that one of the free parameters in the fit is uniquely linked to the reference region and is common to all voxels. A two-step approach is proposed that t...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.26530
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:Anisotropic transverse R2 (1/T2 ) relaxation of water proton is sensitive to cartilage degenerative changes. The purpose is to develop an efficient method to extract this relaxation metric in clinical studies. METHODS:Anisotropic R2 can be measured inefficiently by standard R2 mapping after removing an isotrop...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27621
更新日期:2019-06-01 00:00:00
abstract:PURPOSE:Quantitative myocardial perfusion mapping has advantages over qualitative assessment, including the ability to detect global flow reduction. However, it is not clinically available and remains a research tool. Building upon the previously described imaging sequence, this study presents algorithm and implementat...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27954
更新日期:2020-02-01 00:00:00
abstract::The resolution and homogeneity limitations of echo-planar imaging (EPI) are overcome by zoom imaging of an easily shimmed localized volume. Use of the stimulated echo enables single-shot localization. In vivo 0.5-mm resolution EPI images of selected regions of a cat brain at 4.7 T are presented. ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910140225
更新日期:1990-05-01 00:00:00
abstract:PURPOSE:This work describes the construction and evaluation of a bilateral 32-channel receive array for breast imaging at 7T. METHODS:The receive array consisted of 32 receive coils, placed on two 3D-printed hemispherical formers. Each side of the receive array consisted of 16 receive loops, each loop having a corresp...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.28425
更新日期:2021-01-01 00:00:00
abstract::The aim of this study was to quantify changes in thoracic aortic wall shear stress (WSS) in asymptomatic patients with Marfan syndrome (MFS) compared with healthy controls. WSS in the thoracic aorta was quantified based on time-resolved 3D phase contrast MRI with three-directional velocity encoding (4D flow MRI, tempo...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24562
更新日期:2013-10-01 00:00:00
abstract:PURPOSE:To directly compare in vivo versus postmortem second-order motion-compensated spin-echo diffusion tensor imaging of the porcine heart. METHODS:Second-order motion-compensated spin-echo cardiac diffusion tensor imaging was performed during systolic contraction in vivo and repeated upon cardiac arrest by bariumc...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.26871
更新日期:2018-04-01 00:00:00
abstract::Proton magnetic resonance spectroscopy ((1)H MRS) was used to determine brain temperature in healthy volunteers. Partially water-suppressed (1)H MRS data sets were acquired at 3T from four different gray matter (GM)/white matter (WM) volumes. Brain temperatures were determined from the chemical-shift difference betwee...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21100
更新日期:2007-01-01 00:00:00
abstract::An improved double quantum coherence (DQC) filter for the selective in vivo detection of glutathione (GSH) in the human brain at 1.5 Tesla is presented. The goal was to minimize contamination of the DQC-filtered GSH signal at 2.9 ppm with contributions arising from GABA. The modification consists of tailoring the freq...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1094
更新日期:2001-04-01 00:00:00
abstract:PURPOSE:In this work, 22 configurations for remote radiofrequency (RF) coil arrays consisting of different transmit element designs for 7 Tesla (T) ultrahigh-field MRI are compared by numerical simulations. METHODS:Investigated transmit RF element types are rectangular loops, micro striplines, micro striplines with me...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.26704
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:To develop an MRI acquisition and reconstruction framework for volumetric cine visualization of the fetal heart and great vessels in the presence of maternal and fetal motion. METHODS:Four-dimensional (4D) depiction was achieved using a highly-accelerated multi-planar real-time balanced steady-state free prece...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27798
更新日期:2019-09-01 00:00:00
abstract::Chemical shifts were extracted from in vivo 3-dimensional 31P NMR CSI data and pH images were constructed. The images could spatially resolve tissue pH ranging from 5.8 to 7.2 (with uncertainty of 0.11-0.17 pH unit) in an ischemia-reperfusion model of diabetic rat calf muscles. ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910290214
更新日期:1993-02-01 00:00:00
abstract::Current implementations of coronary artery magnetic resonance angiography (MRA) suffer from limited coverage of the coronary arterial system. Whole-heart coronary MRA was implemented based on a free-breathing steady-state free-precession (SSFP) technique with magnetization preparation. The technique was compared to a ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10653
更新日期:2003-12-01 00:00:00
abstract::Myocardial pH has been shown in animal models to be a sensitive indicator of ischemia. In vivo measurement in humans using 31p magnetic resonance spectroscopy is complicated by the overlap of blood 2,3-diphosphoglycerate peaks with the P(i) peak used for pH measurement. A "saturation transfer" method combined with spa...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/(sici)1522-2594(199901)41:1<198::aid-mrm28
更新日期:1999-01-01 00:00:00
abstract::It has been suggested that orientational changes in the collagen network of articular cartilage account for the depthwise T2 anisotropy of MRI through the magic angle effect. To investigate the relationship between laminar T2 appearance and collagen organization (anisotropy), bovine osteochondral plugs (N = 9) were T2...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1218
更新日期:2001-09-01 00:00:00
abstract:PURPOSE:To optimize 3D radial ultrashort echo time MRI for high resolution whole-lung imaging. METHODS:3D radial ultrashort echo time was implemented on a 3T scanner to investigate the effects of: (1) limited field-of-view excitation, (2) variable density readouts, and (3) radial oversampling. Improvements in noise pe...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24570
更新日期:2013-11-01 00:00:00
abstract::Image reconstruction of tagged cardiac MR images using complementary spatial modulation of magnetization (CSPAMM) requires the subtraction of two complex datasets to remove the untagged signal. Although the resultant images typically have sharper and more persistent tags than images formed without complementary taggin...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10523
更新日期:2003-08-01 00:00:00
abstract:PURPOSE:To determine the feasibility of employing the prior knowledge of well-separated chemical exchange saturation transfer (CEST) signals in the 9.4 T Z-spectrum to separate overlapping CEST signals acquired at 3 T, using a deep learning approach trained with 3 T and 9.4 T CEST spectral data from brains of the same ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27690
更新日期:2019-06-01 00:00:00
abstract::Magnetic field homogeneity is of major concern for in vivo spectroscopy, and with the increased use of volumetric chemical shift imaging (CSI) techniques, the ability to shim over a large volume of tissue is now one of the primary limiting constraints in performing these studies. In vivo shimming is routinely performe...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910400307
更新日期:1998-09-01 00:00:00
abstract::The commercial synthetic homopolypeptide polyaspartate (average MW = 30,000, approximately 220 monomers) in solution quantitatively binds up to 40 mol Gd3+ ions per mole of polyaspartate. The water proton relaxivity of the solutions is far higher than that of clinically used or commonly investigated gadolinium(III) co...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910310109
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:As the premiere modality for brain imaging, MRI could find wider applicability if lightweight, portable systems were available for siting in unconventional locations such as intensive care units, physician offices, surgical suites, ambulances, emergency rooms, sports facilities, or rural healthcare sites. METH...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25147
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:To analyze the effect of B0 field drift on multivoxel MR spectroscopic imaging and to propose an approach for its correction. THEORY AND METHODS:It is shown, both theoretically and in a phantom, that for ∼30 min acquisitions a linear B0 drift (∼0.1 ppm/h) will cause localization errors that can reach several v...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24536
更新日期:2013-10-01 00:00:00
abstract:PURPOSE:Correlation imaging is a previously developed high-speed MRI framework that converts parallel imaging reconstruction into the estimate of correlation functions. The presented work aims to demonstrate this framework can provide a speed gain over parallel imaging by estimating k-space variant correlation function...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.26818
更新日期:2018-03-01 00:00:00
abstract::In radiotherapy, target tissues are defined best on MR images due to their superior soft tissue contrast. Computed tomography imaging is geometrically accurate and it is needed for dose calculation and generation of reference images for treatment localization. Co-registration errors between MR and computed tomography ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1002/mrm.24459
更新日期:2013-07-01 00:00:00
abstract::Localized 1H NMR homonuclear J editing spectroscopy was used to measure the concentration of 2-pyrrolidinone (PRDN) in the human occipital lobe of five normal and six epileptic subjects taking vigabatrin. PRDN is a lactam cyclization product of gamma-aminobutyric acid (GABA). From a localized volume of 13.5 cm3 in the...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/(sici)1522-2594(199905)41:5<889::aid-mrm6>
更新日期:1999-05-01 00:00:00