Abstract:
PURPOSE:Subendocardial dark-rim artifacts (DRAs) remain a major concern in first-pass perfusion (FPP) myocardial MRI and may lower the diagnostic accuracy for detection of ischemia. A major source of DRAs is the "Gibbs ringing" effect. We propose an optimized radial acquisition strategy aimed at eliminating ringing-induced DRAs in FPP. THEORY AND METHODS:By studying the underlying point spread function (PSF), we show that optimized radial sampling with a simple reconstruction method can eliminate the oscillations in the PSF that cause ringing artifacts. We conducted realistic MRI phantom experiments and in vivo studies (n = 12 healthy humans) to evaluate the artifact behavior of the proposed imaging scheme in comparison to a conventional Cartesian imaging protocol. RESULTS:Simulations and phantom experiments verified our theoretical expectations. The in vivo studies showed that optimized radial imaging is capable of significantly reducing DRAs in the early myocardial enhancement phase (during which the ringing effect is most prominent and may obscure perfusion defects) while providing similar resolution and image quality compared with conventional Cartesian imaging. CONCLUSION:The developed technical framework and results demonstrate that, in comparison to conventional Cartesian techniques, optimized radial imaging with the proposed optimizations significantly reduces the prevalence and spatial extent of DRAs in FPP imaging.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Sharif B,Dharmakumar R,LaBounty T,Arsanjani R,Shufelt C,Thomson L,Merz CN,Berman DS,Li Ddoi
10.1002/mrm.24913subject
Has Abstractpub_date
2014-07-01 00:00:00pages
124-36issue
1eissn
0740-3194issn
1522-2594journal_volume
72pub_type
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