Selection and evaluation of optimal two-dimensional CAIPIRINHA kernels applied to time-resolved three-dimensional CE-MRA.

Abstract:

PURPOSE:To develop and validate a method for choosing the optimal two-dimensional CAIPIRINHA kernel for subtraction contrast-enhanced MR angiography (CE-MRA) and estimate the degree of image quality improvement versus that of some reference acceleration parameter set at R ≥ 8. METHODS:A metric based on patient-specific coil calibration information was defined for evaluating optimality of CAIPIRINHA kernels as applied to subtraction CE-MRA. Evaluation in retrospective studies using archived coil calibration data from abdomen, calf, foot, and hand CE-MRA exams was accomplished with an evaluation metric comparing the geometry factor (g-factor) histograms. Prospective calf, foot, and hand CE-MRA studies were evaluated with vessel signal-to-noise ratio (SNR). RESULTS:Retrospective studies show g-factor improvement for the selected CAIPIRINHA kernels was significant in the feet, moderate in the abdomen, and modest in the calves and hands. Prospective CE-MRA studies using optimal CAIPIRINHA show reduced noise amplification with identical acquisition time in studies of the feet, with minor improvements in the hands and calves. CONCLUSION:A method for selection of the optimal CAIPIRINHA kernel for high (R ≥ 8) acceleration CE-MRA exams given a specific patient and receiver array was demonstrated. CAIPIRINHA optimization appears valuable in accelerated CE-MRA of the feet and to a lesser extent in the abdomen.

journal_name

Magn Reson Med

authors

Weavers PT,Borisch EA,Riederer SJ

doi

10.1002/mrm.25366

subject

Has Abstract

pub_date

2015-06-01 00:00:00

pages

2234-42

issue

6

eissn

0740-3194

issn

1522-2594

journal_volume

73

pub_type

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