Optimum flip-angles for exciting NMR with uncertain T1 values.

Abstract:

:T1 is often ill-determined. This means that an Ernst angle excitation often cannot be precisely defined for the simple pulse and acquire experiment. Here, published 31P T1 values of metabolites in human muscle, liver, heart, and brain are archived, some new data on heart and brain added, and overall confidence intervals determined. Strategies for setting the flip-angle based on the confidence intervals are examined, and an optimum flip-angle derived which minimizes the signal loss relative to what could have been realized if T1 were precisely known. With such optimized pulses, signal loss can be limited to < or = 14% for up to a 10-fold variation in T1, with TR < or = T1. The effect that an uncertainty in T1 by a factor of two has on the saturation corrected signal is limited to < or = 20% in the optimum flip-angle experiment. Adiabatic B1-independent rotation phase-cycled (BIRP) excitation pulses are ideal as optimum flip-angle pulses as they can be prescribed without calibration.

journal_name

Magn Reson Med

authors

Bottomley PA,Ouwerkerk R

doi

10.1002/mrm.1910320120

subject

Has Abstract

pub_date

1994-07-01 00:00:00

pages

137-41

issue

1

eissn

0740-3194

issn

1522-2594

journal_volume

32

pub_type

杂志文章
  • Combined functional and viability cardiac MR imaging in a single breathhold.

    abstract::The combination of cardiac viability and functional information enhances the identification of different heart tissues in the setting of ischemic heart disease. A method has recently been proposed for obtaining black-blood delayed-enhancement (DE) viability images using the stimulated-echo acquisition mode (STEAM) MRI...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21390

    authors: Ibrahim el-SH,Stuber M,Kraitchman DL,Weiss RG,Osman NF

    更新日期:2007-10-01 00:00:00

  • Magnetic resonance imaging of myocardial kinematics. Technique to detect, localize, and quantify the strain rates of the active human myocardium.

    abstract::A magnetic resonance imaging (MRI) method is presented to detect, localize, and quantify myocardial kinematics by measuring the material rate-of-strain tensor at each pixel in gated NMR images of the heart. The immediate, local effect of muscular activity is self-deformation, and the strain tensor is the basic mathema...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910270107

    authors: Wedeen VJ

    更新日期:1992-09-01 00:00:00

  • In vivo study of microbubbles as an MR susceptibility contrast agent.

    abstract::The potential application of gas microbubbles as a unique intravascular susceptibility contrast agent for MRI has not been fully explored. In this study, the MR susceptibility effect of an ultrasound microbubble contrast agent, Optison, was studied with rat liver imaging at 7 T. Optison suspension in two different dos...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20181

    authors: Wong KK,Huang I,Kim YR,Tang H,Yang ES,Kwong KK,Wu EX

    更新日期:2004-09-01 00:00:00

  • Localization errors in MR spectroscopic imaging due to the drift of the main magnetic field and their correction.

    abstract:PURPOSE:To analyze the effect of B0 field drift on multivoxel MR spectroscopic imaging and to propose an approach for its correction. THEORY AND METHODS:It is shown, both theoretically and in a phantom, that for ∼30 min acquisitions a linear B0 drift (∼0.1 ppm/h) will cause localization errors that can reach several v...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24536

    authors: Tal A,Gonen O

    更新日期:2013-10-01 00:00:00

  • Generalized matched filtering for time-resolved MR angiography of pulsatile flow.

    abstract::Generating flow-specific images (arteriograms, venograms) with optimal signal-to-noise ratios for time-resolved MR angiography is a conditional maximum problem, and its solutions are generalized matched filters. We have investigated six matched filters, corresponding to all possible combinations of three flow suppress...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910300511

    authors: Wang Y,Weber DM,Korosec FR,Mistretta CA,Grist TM,Swan JS,Turski PA

    更新日期:1993-11-01 00:00:00

  • Mathematical optimization of contrast concentration for T1-weighted spoiled gradient echo imaging.

    abstract:PURPOSE:To develop and validate closed form mathematical expressions that predict the optimal contrast agent concentration for the maximum T1-weighted spoiled gradient echo (SGRE) signal. THEORY AND METHODS:Gadolinium and iron-based contrast agents can have significant transverse relaxivity that leads to signal dropou...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25744

    authors: Reeder SB,Smith MR,Hernando D

    更新日期:2016-04-01 00:00:00

  • Measurement of 129Xe gas apparent diffusion coefficient anisotropy in an elastase-instilled rat model of emphysema.

    abstract::Hyperpolarized noble gas ((3)He and (129)Xe) apparent diffusion coefficient (ADC) measurements have shown remarkable sensitivity to microstructural (i.e., alveolar) changes in the lung, particularly emphysema. The ADC of hyperpolarized noble gases depends strongly on the diffusion time (Δ), and (3)He ADC has been show...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24224

    authors: Boudreau M,Xu X,Santyr GE

    更新日期:2013-01-01 00:00:00

  • Dynamic oxygen-enhanced MRI reflects diffusing capacity of the lung.

    abstract::The purpose of this study was to demonstrate the feasibility of dynamic oxygen-enhanced MRI in a clinical setting. We hypothesized that dynamic oxygen enhancement can reflect the regional diffusing capacity of the lung. Ten patients with pulmonary emphysema and seven healthy volunteers were examined with a respiratory...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10168

    authors: Ohno Y,Hatabu H,Takenaka D,Van Cauteren M,Fujii M,Sugimura K

    更新日期:2002-06-01 00:00:00

  • Robust estimation of spatially variable noise fields.

    abstract::Consideration of spatially variable noise fields is becoming increasingly necessary in MRI given recent innovations in artifact identification and statistically driven image processing. Fast imaging methods enable study of difficult anatomical targets and improve image quality but also increase the spatial variability...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22013

    authors: Landman BA,Bazin PL,Smith SA,Prince JL

    更新日期:2009-08-01 00:00:00

  • A two-stage approach for measuring vascular water exchange and arterial transit time by diffusion-weighted perfusion MRI.

    abstract::Changes in the exchange rate of water across the blood-brain barrier, denoted k(w), may indicate blood-brain barrier dysfunction before the leakage of large-molecule contrast agents is observable. A previously proposed approach for measuring k(w) is to use diffusion-weighted arterial spin labeling to measure the vascu...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.23104

    authors: St Lawrence KS,Owen D,Wang DJ

    更新日期:2012-05-01 00:00:00

  • Concentrations of human cardiac phosphorus metabolites determined by SLOOP 31P NMR spectroscopy.

    abstract::Human cardiac 31P nuclear magnetic resonance (NMR) spectra are usually quantified in relative terms, i.e., the ratio of metabolite signals is calculated. If 31P NMR spectroscopy of the heart is to emerge as a clinically relevant diagnostic modality, reliable quantification of absolute concentrations of 31P metabolites...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1522-2594(199904)41:4<657::aid-mrm3>

    authors: Meininger M,Landschütz W,Beer M,Seyfarth T,Horn M,Pabst T,Haase A,Hahn D,Neubauer S,von Kienlin M

    更新日期:1999-04-01 00:00:00

  • Design of spectral-spatial phase prewinding pulses and their use in small-tip fast recovery steady-state imaging.

    abstract:PURPOSE:Spectrally selective "prewinding" radiofrequency pulses can counteract B0 inhomogeneity in steady-state sequences, but can only prephase a limited range of off-resonance. We propose spectral-spatial small-tip angle prewinding pulses that increase the off-resonance bandwidth that can be successfully prephased by...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26794

    authors: Williams SN,Nielsen JF,Fessler JA,Noll DC

    更新日期:2018-03-01 00:00:00

  • Single-scan MRI with exceptional resilience to field heterogeneities.

    abstract:PURPOSE:Single-scan two-dimensional MRI has been generally constrained to acquisitions in high quality magnets. This study introduces a methodology, cross-term spatiotemporal encoding (xSPEN), that delivers such images under much poorer external field conditions. METHODS:xSPEN departs from conventional k-space scannin...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26145

    authors: Zhang Z,Seginer A,Frydman L

    更新日期:2017-02-01 00:00:00

  • Improved MRI R2 * relaxometry of iron-loaded liver with noise correction.

    abstract::Accurate and reproducible MRI R2 * relaxometry for tissue iron quantification is important in managing transfusion-dependent patients. MRI data are often acquired using array coils and reconstructed by the root-sum-square algorithm, and as such, measured signals follow the noncentral chi distribution. In this study, t...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24607

    authors: Feng Y,He T,Gatehouse PD,Li X,Harith Alam M,Pennell DJ,Chen W,Firmin DN

    更新日期:2013-12-01 00:00:00

  • Magnitude image CSPAMM reconstruction (MICSR).

    abstract::Image reconstruction of tagged cardiac MR images using complementary spatial modulation of magnetization (CSPAMM) requires the subtraction of two complex datasets to remove the untagged signal. Although the resultant images typically have sharper and more persistent tags than images formed without complementary taggin...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10523

    authors: NessAiver M,Prince JL

    更新日期:2003-08-01 00:00:00

  • x-f Choice: reconstruction of undersampled dynamic MRI by data-driven alias rejection applied to contrast-enhanced angiography.

    abstract::A technique for reconstructing dynamic undersampled MRI data, termed "x-f choice," was developed and applied to dynamic contrast-enhanced MR angiography (DCE-MRA). Regular undersampling in k-t space (a hybrid of k-space and time) creates aliasing in the conjugate x-f space that must be resolved. When regions in the ob...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21008

    authors: Malik SJ,Schmitz S,O'Regan D,Larkman DJ,Hajnal JV

    更新日期:2006-10-01 00:00:00

  • In vivo MR elastography of the prostate gland using a transurethral actuator.

    abstract::Conventional approaches for MR elastography (MRE) using surface drivers have difficulty achieving sufficient shear wave propagation in the prostate gland due to attenuation. In this study we evaluate the feasibility of generating shear wave propagation in the prostate gland using a transurethral device. A novel transu...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22038

    authors: Chopra R,Arani A,Huang Y,Musquera M,Wachsmuth J,Bronskill M,Plewes D

    更新日期:2009-09-01 00:00:00

  • Self-calibrated correlation imaging with k-space variant correlation functions.

    abstract:PURPOSE:Correlation imaging is a previously developed high-speed MRI framework that converts parallel imaging reconstruction into the estimate of correlation functions. The presented work aims to demonstrate this framework can provide a speed gain over parallel imaging by estimating k-space variant correlation function...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26818

    authors: Li Y,Edalati M,Du X,Wang H,Cao JJ

    更新日期:2018-03-01 00:00:00

  • Susceptibility contrast imaging of cerebral blood volume: human experience.

    abstract::Magnetic resonance (MR) can offer a unique window on the structure/function relationships in the brain, by utilizing the established link between tissue function, metabolism, and hemodynamics. This report focuses on recent applications of MR-based cerebral blood volume (CBV) imaging in humans. Our methodology uses hig...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910220227

    authors: Rosen BR,Belliveau JW,Aronen HJ,Kennedy D,Buchbinder BR,Fischman A,Gruber M,Glas J,Weisskoff RM,Cohen MS

    更新日期:1991-12-01 00:00:00

  • Effects of anesthesia on renal function and metabolism in rats assessed by hyperpolarized MRI.

    abstract:PURPOSE:Anesthesia is necessary for most animal studies requiring invasive procedures. It is well documented that various types of anesthesia modulate a wide variety of important metabolic and functional processes in the body, and as such, represent a potential limitation in the study design. In the present study, we a...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27165

    authors: Qi H,Mariager CØ,Lindhardt J,Nielsen PM,Stødkilde-Jørgensen H,Laustsen C

    更新日期:2018-11-01 00:00:00

  • Unaliasing by fourier-encoding the overlaps using the temporal dimension (UNFOLD), applied to cardiac imaging and fMRI.

    abstract::In several applications, MRI is used to monitor the time behavior of the signal in an organ of interest; e.g., signal evolution because of physiological motion, activation, or contrast-agent accumulation. Dynamic applications involve acquiring data in a k-t space, which contains both temporal and spatial information. ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1522-2594(199911)42:5<813::aid-mrm1>

    authors: Madore B,Glover GH,Pelc NJ

    更新日期:1999-11-01 00:00:00

  • Strategies for improved temporal and spectral resolution in in vivo oximetric imaging using time-domain EPR.

    abstract::A radiofrequency (RF) time-domain electron paramagnetic resonance (EPR) instrument operating at 300, 600, and 750 MHz was used to image tumor hypoxia with high spatial and temporal resolution. A high-speed signal-averaging Peripheral Component Interconnect (PCI) board with flexibility in the input signal level and the...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21194

    authors: Devasahayam N,Subramanian S,Murugesan R,Hyodo F,Matsumoto K,Mitchell JB,Krishna MC

    更新日期:2007-04-01 00:00:00

  • Reduction of B1 sensitivity in selective single-slab 3D turbo spin echo imaging with very long echo trains.

    abstract::Single-slab 3D turbo/fast spin echo (SE) imaging with very long echo trains was recently introduced with slab selection using a highly selective excitation pulse and short, nonselective refocusing pulses with variable flip angles for high imaging efficiency. This technique, however, is vulnerable to image degradation ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22070

    authors: Park J,Mugler JP 3rd,Hughes T

    更新日期:2009-10-01 00:00:00

  • MR-guided interstitial cryotherapy of the liver with a novel, nitrogen-cooled cryoprobe.

    abstract::The purpose of the study was to test a newly developed, MR-compatible, liquid nitrogen-cooled cryoprobe. The probe has an outer diameter of 3.5 mm and was specifically developed for percutaneous, MR-guided, interstitial cryotherapy. The probe was inserted percutaneously into the livers of 10 rabbits. The cryotherapy p...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910390304

    authors: Tacke J,Adam G,Speetzen R,Brucksch K,Bücker A,Heshel I,Prescher A,van Vaals JJ,Hunter DW,Rau G,Günther RW

    更新日期:1998-03-01 00:00:00

  • A flexible nested sodium and proton coil array with wideband matching for knee cartilage MRI at 3T.

    abstract:PURPOSE:We describe a 2 × 6 channel sodium/proton array for knee MRI at 3T. Multielement coil arrays are desirable because of well-known signal-to-noise ratio advantages over volume and single-element coils. However, low tissue-coil coupling that is characteristic of coils operating at low frequency can make the potent...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26017

    authors: Brown R,Lakshmanan K,Madelin G,Alon L,Chang G,Sodickson DK,Regatte RR,Wiggins GC

    更新日期:2016-10-01 00:00:00

  • Convex gradient optimization for increased spatiotemporal resolution and improved accuracy in phase contrast MRI.

    abstract:PURPOSE:To evaluate convex gradient optimization (CVX) for increased spatiotemporal resolution and improved accuracy for phase-contrast MRI (PC-MRI). METHODS:A conventional flow-compensated and flow-encoded (FCFE) PC-MRI sequence was compared with a CVX PC-MRI sequence using numerical simulations, flow phantom experim...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25059

    authors: Middione MJ,Wu HH,Ennis DB

    更新日期:2014-12-01 00:00:00

  • Image contrast using the secondary and tertiary eigenvectors in diffusion tensor imaging.

    abstract::Diffusion tensor imaging (DTI) is a new imaging modality that can provide unique information on brain white matter anatomy. Measurements of water diffusion constant along multiple axes are fitted to a tensor model, from which the diffusion anisotropy and dominant fiber orientation can be estimated. Even though the ten...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20767

    authors: Zhang J,van Zijl PC,Mori S

    更新日期:2006-02-01 00:00:00

  • Cocaine administration decreases functional connectivity in human primary visual and motor cortex as detected by functional MRI.

    abstract::Functional magnetic resonance imaging (fMRI) was conducted to observe the effects of cocaine administration on the physiological fluctuations of fMRI signal in two brain regions. Seven long-term cocaine users with an average age of 32 years and 8 years of cocaine use history were recruited for the study. A T2*-weighte...

    journal_title:Magnetic resonance in medicine

    pub_type: 临床试验,杂志文章

    doi:10.1002/(sici)1522-2594(200001)43:1<45::aid-mrm6>3

    authors: Li SJ,Biswal B,Li Z,Risinger R,Rainey C,Cho JK,Salmeron BJ,Stein EA

    更新日期:2000-01-01 00:00:00

  • B0 concomitant field compensation for MRI systems employing asymmetric transverse gradient coils.

    abstract:PURPOSE:Imaging gradients result in the generation of concomitant fields, or Maxwell fields, which are of increasing importance at higher gradient amplitudes. These time-varying fields cause additional phase accumulation, which must be compensated for to avoid image artifacts. In the case of gradient systems employing ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26790

    authors: Weavers PT,Tao S,Trzasko JD,Frigo LM,Shu Y,Frick MA,Lee SK,Foo TK,Bernstein MA

    更新日期:2018-03-01 00:00:00

  • Compartmental study of T(1) and T(2) in rat brain and trigeminal nerve in vivo.

    abstract::The integrated T(1)-T(2) characteristics of rat brain and trigeminal nerve water were studied in vivo using a rapid method for acquiring a series of images that depend on T(1) and T(2) relaxation times. Gray matter regions showed only one signal component in both the T(1) and T(2) domains. Trigeminal nerve, however, w...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10060

    authors: Does MD,Gore JC

    更新日期:2002-02-01 00:00:00