Hyperpolarized 13C NMR detects rapid drug-induced changes in cardiac metabolism.

abstract：PURPOSE:To develop a fast protocol for measuring T1 values in the internal carotid artery (ICA), to validate this technique with in vitro measurements, and to evaluate its reproducibility. METHODS:A modified Look-Locker sequence was optimized to enable rapid determination of T1 in the ICA at 3T. T1 values from the ICA...

journal_title：Magnetic resonance in medicine

authors： Li W,Liu P,Lu H,Strouse JJ,van Zijl PCM,Qin Q

更新日期：2017-06-01 00:00:00

abstract：:Proton magnetic resonance spectroscopy ((1)H MRS) was used to determine brain temperature in healthy volunteers. Partially water-suppressed (1)H MRS data sets were acquired at 3T from four different gray matter (GM)/white matter (WM) volumes. Brain temperatures were determined from the chemical-shift difference betwee...

journal_title：Magnetic resonance in medicine

authors： Childs C,Hiltunen Y,Vidyasagar R,Kauppinen RA

更新日期：2007-01-01 00:00:00

abstract：:Evaluation of water diffusion in the brain has revealed both fast- and slow-diffusing water populations. It has been suggested that these populations represent extra- and intracellular water, respectively. We have identified and characterized both populations in the intracellular space of the Xenopus oocyte. We have a...

journal_title：Magnetic resonance in medicine

authors： Sehy JV,Ackerman JJ,Neil JJ

更新日期：2002-11-01 00:00:00

abstract：:MRI has become an important tool to noninvasively assess global and regional cardiac function, infarct size, or myocardial blood flow in surgically or genetically modified mouse models of human heart disease. Constraints on scan time due to sensitivity to general anesthesia in hemodynamically compromised mice frequent...

journal_title：Magnetic resonance in medicine

authors： Schneider JE,Lanz T,Barnes H,Stork LA,Bohl S,Lygate CA,Ordidge RJ,Neubauer S

更新日期：2011-01-01 00:00:00

abstract：:This study aims to assess whether an alternative method, that is based on volumetric surface detection (VoSD) without tracing and is totally free of geometric assumptions, can improve the reproducibility of right ventricular (RV) volume quantification from cardiac magnetic resonance (CMR) images, in comparison with a ...

journal_title：Magnetic resonance in medicine

authors： Catalano O,Corsi C,Antonaci S,Moro G,Mussida M,Frascaroli M,Baldi M,Caiani E,Lamberti C,Cobelli F

更新日期：2007-03-01 00:00:00

abstract：PURPOSE:To illustrate the potential bias caused by imaging gradients in correlation MRI sequences using longitudinal magnetization storage (LS) and examine the case of filter exchange imaging (FEXI) yielding maps of the apparent exchange rate (AXR). METHODS:The effects of imaging gradients in FEXI were observed on yea...

journal_title：Magnetic resonance in medicine

authors： Lasič S,Lundell H,Topgaard D,Dyrby TB

更新日期：2018-04-01 00:00:00

abstract：:Changes in molecular expression or apoptotic behavior, induced by malignant transformation or anticancer treatment, are frequently reflected in cellular metabolism and oxygen consumption. A technique to monitor oxygen consumption, cell physiology, and metabolism noninvasively would provide a better understanding of in...

journal_title：Magnetic resonance in medicine

authors： Pilatus U,Aboagye E,Artemov D,Mori N,Ackerstaff E,Bhujwalla ZM

更新日期：2001-05-01 00:00:00

abstract：:With the advent of breath-hold MR cardiac imaging techniques, the minimization of TR and TE for oblique planes has become a critical issue. The slew rates and maximum currents of gradient amplifiers limit the minimum possible TR and TE by adding dead-periods to the pulse sequences. We propose a method of designing gra...

journal_title：Magnetic resonance in medicine

authors： Atalar E,McVeigh ER

更新日期：1994-12-01 00:00:00

abstract：:In the ongoing quest for faster imaging and higher spatial resolution, several methods have been developed to speed up data acquisition by incorporating prior information about the object being imaged. This study shows that many of these methods can be integrated into a single common equation. The unified framework pr...

journal_title：Magnetic resonance in medicine

authors： Tsao J,Behnia B,Webb AG

更新日期：2001-10-01 00:00:00

abstract：:Dynamic contrast-enhanced MRI data in vertebral bone marrow (vBM) are currently analyzed with descriptive indices. The purpose of this study was to develop and evaluate a quantitative approach, considering the tissue composition of vBM. Therefore, a measurement of the water fraction, f(wat), and the precontrast relaxa...

journal_title：Magnetic resonance in medicine

authors： Biffar A,Sourbron S,Schmidt G,Ingrisch M,Dietrich O,Reiser MF,Baur-Melnyk A

更新日期：2010-07-01 00:00:00

abstract：:A new strategy for a quantitative measurement of regional pulmonary ventilation using hyperpolarized helium-3 (3He) MRI has been developed. The method employs the build-up of the signal intensity after a variable number of (3)He breaths. A mathematical model of the signal dynamics is presented, from which the local ve...

journal_title：Magnetic resonance in medicine

authors： Deninger AJ,Månsson S,Petersson JS,Pettersson G,Magnusson P,Svensson J,Fridlund B,Hansson G,Erjefeldt I,Wollmer P,Golman K

更新日期：2002-08-01 00:00:00

abstract：PURPOSE:To compare experimental transverse relaxivities of iron oxide nanocrystals (IONC) as a function of clustering and magnetic field strength with different theoretical model predictions. THEORY AND METHODS:Well-defined IONC clusters in nanoemulsions (NEs) of which both size and IONC loading could be judiciously t...

journal_title：Magnetic resonance in medicine

authors： Hak S,Goa PE,Stenmark S,Bjerkholt FF,Haraldseth O

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To investigate the relative gain in sensitivity of five histology coils designed in-house to accommodate tissue sections of various sizes and compare with commercial mouse head coils. METHODS:The coil set was tailored to house tissue sections ranging from 5 to1000 µm encased in either glass slides or coverslip...

journal_title：Magnetic resonance in medicine

authors： Hoang DM,Voura EB,Zhang C,Fakri-Bouchet L,Wadghiri YZ

更新日期：2014-05-01 00:00:00

abstract：:Whole-body NMR imaging antennas (probes) are strongly affected by the inevitable magnetic and controllable dielectric losses. Using a convenient parallelepiped model, the magnetic losses are evaluated. By introducing the "ideal power gain," the best possible antenna performance is delimited as a function of the freque...

journal_title：Magnetic resonance in medicine

authors： Sergiadis G

更新日期：1985-08-01 00:00:00

abstract：:Multiple images acquired simultaneously from an array of surface coils can be combined to give a composite image with an improved signal-to-noise ratio (SNR) and a large field of view. The composite images' SNR can be optimized by taking advantage of noise correlations between coils and phase shifts induced by surface...

journal_title：Magnetic resonance in medicine

authors： Hayes CE,Roemer PB

更新日期：1990-11-01 00:00:00

abstract：:Hyperpolarized noble gas ((3)He and (129)Xe) apparent diffusion coefficient (ADC) measurements have shown remarkable sensitivity to microstructural (i.e., alveolar) changes in the lung, particularly emphysema. The ADC of hyperpolarized noble gases depends strongly on the diffusion time (Δ), and (3)He ADC has been show...

journal_title：Magnetic resonance in medicine

authors： Boudreau M,Xu X,Santyr GE

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:Quantitative susceptibility map (QSM) reconstruction is ill posed due to the zero values on the "magic angle cone" that make the maps prone to streaking artifacts. We propose projection onto convex sets (POCS) in the method of steepest descent (SD) for QSM reconstruction. METHODS:Two convex projections, an obj...

journal_title：Magnetic resonance in medicine

authors： Deng W,Boada F,Poser BA,Schirda C,Stenger VA

更新日期：2015-02-01 00:00:00

abstract：:Spinal cord (SC) motion is thought to be the dominant source of error in current diffusion and spinal functional MRI (fMRI) methods. However, until now, such motion has not been well characterized in three dimensions. While previous studies have predominantly examined motion in the superior/inferior (S/I) direction, t...

journal_title：Magnetic resonance in medicine

authors： Figley CR,Stroman PW

更新日期：2007-07-01 00:00:00

abstract：:The purpose of the present study was to examine whether single human carcinoma cells labeled with iron oxide nanoparticles could be detected by magnetic resonance (MR) imaging on a clinical 3-T scanner using a surface coil only. WiDr human colon carcinoma cells were loaded with two kinds of iron oxide nanoparticles di...

journal_title：Magnetic resonance in medicine

authors： Pinkernelle J,Teichgräber U,Neumann F,Lehmkuhl L,Ricke J,Scholz R,Jordan A,Bruhn H

更新日期：2005-05-01 00:00:00

abstract：PURPOSE:This study evaluates biochemical imbalances in a rat model that reflects dysfunctional pathways in migraine. The high sensitivity and spectral dispersion available to 1 H MRS at 21.1 T expands metabolic profiling in this migraine model to include lactate (Lac), taurine (Tau), aspartate, and Gly-a mixture of gly...

journal_title：Magnetic resonance in medicine

authors： Abad N,Rosenberg JT,Roussel T,Grice DC,Harrington MG,Grant SC

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:We aim to leverage the power of deep-learning with high-fidelity training data to improve the reliability and processing speed of hemodynamic mapping with MR fingerprinting (MRF) arterial spin labeling (ASL). METHODS:A total of 15 healthy subjects were studied on a 3T MRI. Each subject underwent 10 runs of a m...

journal_title：Magnetic resonance in medicine

authors： Fan H,Su P,Huang J,Liu P,Lu H

更新日期：2021-04-01 00:00:00

abstract：:Longitudinal water proton relaxation rates of methemoglobin solutions show a strong dependence on temperature and pH. The increase of the relaxation rates with temperature is associated with shortened exchange lifetime of the coordinated water molecule. An accurate measurement of the relaxation rate of methemoglobin s...

journal_title：Magnetic resonance in medicine

authors： Aime S,Fasano M,Paoletti S,Arnelli A,Ascenzi P

更新日期：1995-06-01 00:00:00

abstract：:MR images acquired by using an arterial spin-labeling technique showed spatial and temporal variations of perfusion in the skeletal muscle of exercising humans. Perfusion measurements made during plantar flexion exercise in normal volunteers were consistent with those obtained by traditional techniques reported in the...

journal_title：Magnetic resonance in medicine

authors： Frank LR,Wong EC,Haseler LJ,Buxton RB

更新日期：1999-08-01 00:00:00

abstract：:Magnetic resonance imaging measurements of the apparent rate of water diffusion in tumors are sensitive to variations in tissue cellularity, which have been shown useful for characterizing tumors and their responses to treatments. However, because of technical limitations on most MRI systems, conventional pulse gradie...

journal_title：Magnetic resonance in medicine

authors： Xu J,Does MD,Gore JC

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:To obtain three-dimensional (3D) MR angiography having high contrast between vessel and stationary background tissue, a novel technique called sliding time of flight (TOF) is proposed. METHODS:The proposed method relies on the property that flow-related enhancement (FRE) is maximized at the blood-entering slic...

journal_title：Magnetic resonance in medicine

authors： Choi J,Seo H,Lim Y,Han Y,Park H

更新日期：2015-03-01 00:00:00

abstract：:In the dynamic nuclear polarization process, microwave irradiation facilitates exchange of polarization from a radical's unpaired electron to nuclear spins at cryogenic temperatures, increasing polarization by >10,000. Doping samples with Gd(3+) ions further increases the achievable solid-state polarization. However, ...

journal_title：Magnetic resonance in medicine

authors： Gordon JW,Fain SB,Rowland IJ

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:To develop and evaluate a method for volumetric contrast-enhanced MRI of the liver, with high spatial and temporal resolutions, for combined dynamic imaging and MR angiography (MRA) using a single injection of contrast agent. METHODS:An interleaved variable density (IVD) undersampling pattern was implemented i...

journal_title：Magnetic resonance in medicine

authors： Salmani Rahimi M,Korosec FR,Wang K,Holmes JH,Motosugi U,Bannas P,Reeder SB

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:To investigate the effect of realistic microstructural geometry on the susceptibility-weighted MR signal in white matter (WM), with application to demyelination. METHODS:Previous work has modeled susceptibility-weighted signals under the assumption that axons are cylindrical. In this study, we explored the imp...

journal_title：Magnetic resonance in medicine

authors： Xu T,Foxley S,Kleinnijenhuis M,Chen WC,Miller KL

更新日期：2018-01-01 00:00:00

abstract：:Multiple receivers can be utilized to enhance the spatiotemporal resolution of MRI by employing the parallel imaging technique. Previously, we have reported the L-curve Tikhonov regularization technique to mitigate noise amplification resulting from the geometrical correlations between channels in a coil array. Nevert...

journal_title：Magnetic resonance in medicine

authors： Lin FH,Wang FN,Ahlfors SP,Hämäläinen MS,Belliveau JW

更新日期：2007-10-01 00:00:00

abstract：:The natural abundance 13C NMR intensity of the glycogen C1 resonance was measured in the surgically exposed liver of rabbits in vivo (n = 17) by integration from 98 to 104 ppm and compared double blindedly to the subsequent biochemical measurement. Coil loading was measured each time from a reference sphere at the coi...

journal_title：Magnetic resonance in medicine

authors： Gruetter R,Magnusson I,Rothman DL,Avison MJ,Shulman RG,Shulman GI

更新日期：1994-06-01 00:00:00