Investigation of human cervical and upper thoracic spinal cord motion: implications for imaging spinal cord structure and function.

Abstract:

:Spinal cord (SC) motion is thought to be the dominant source of error in current diffusion and spinal functional MRI (fMRI) methods. However, until now, such motion has not been well characterized in three dimensions. While previous studies have predominantly examined motion in the superior/inferior (S/I) direction, the foci of the present study were the anterior/posterior (A/P) and right/left (R/L) components of human cervical and upper thoracic SC motion. Cardiac-gated, turbofast low-angle shot (turbo-FLASH) cinematic MRI was employed at 3T to acquire images of the cord at 24 phases throughout the cardiac cycle. Time-dependent signal fluctuations within voxels adjacent to the cord/cerebrospinal fluid (CSF) interface were then used to measure SC motion, which was found to occur predictably as a function of cardiac activity. Cord movement was largest in the A/P direction, for which principal components of motion were calculated, thereby indicating consistent patterns of SC oscillation that can potentially be used to improve SC imaging.

journal_name

Magn Reson Med

authors

Figley CR,Stroman PW

doi

10.1002/mrm.21260

subject

Has Abstract

pub_date

2007-07-01 00:00:00

pages

185-9

issue

1

eissn

0740-3194

issn

1522-2594

journal_volume

58

pub_type

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