Evidence that both fast and slow water ADC components arise from intracellular space.

abstract：PURPOSE:To optimize radiofrequency (RF) pulses for the selective excitation of dissolved phase (129)Xe that take into account the very short T2*, while simultaneously, minimally exciting the much larger gas signal. METHODS:Numerical simulations of Shinnar le-Roux pulses and binomial coefficient composite-element pulse...

journal_title：Magnetic resonance in medicine

authors： Leung G,Norquay G,Schulte RF,Wild JM

更新日期：2015-01-01 00:00:00

abstract：:MR oximetry requires a T2 measurement that is accurate within 5% in vivo. Simple methods are susceptible to signal loss and tend to underestimate T2. Current methods utilize RF pulses or RF cycling patterns that prevent signal loss at each data acquisition. However, using these methods with imperfect pulses, T2 tends ...

journal_title：Magnetic resonance in medicine

authors： Foltz WD,Stainsby JA,Wright GA

更新日期：1997-11-01 00:00:00

abstract：:Tumor pH is physiologically important since it influences a number of processes relevant to tumorigenesis and therapy. Hence, knowledge of localized pH within tumors would contribute to understanding these processes. The destructiveness, poor spatial resolution, and poor signal-to-noise ratio (SNR) of current technolo...

journal_title：Magnetic resonance in medicine

authors： van Sluis R,Bhujwalla ZM,Raghunand N,Ballesteros P,Alvarez J,Cerdán S,Galons JP,Gillies RJ

更新日期：1999-04-01 00:00:00

abstract：PURPOSE:To develop the simultaneous acquisition of multiple voxels in localized MR spectroscopy (MRS) using sensitivity encoding, allowing reduced total scan time compared to conventional sequential single voxel (SV) acquisition methods. METHODS:Dual volume localization was used to simultaneously excite voxels in both...

journal_title：Magnetic resonance in medicine

authors： Boer VO,Klomp DW,Laterra J,Barker PB

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To improve the quality and speed of electron paramagnetic resonance imaging (EPRI) acquisition by combining a uniform sampling distribution with spinning gradient acquisition. THEORY AND METHODS:A uniform sampling distribution was derived for spinning gradient EPRI acquisition (uniform spinning sampling, USS) ...

journal_title：Magnetic resonance in medicine

authors： Johnson DH,Ahmad R,Liu Y,Chen Z,Samouilov A,Zweier JL

更新日期：2014-02-01 00:00:00

abstract：PURPOSE:To measure the apparent diffusion coefficients (ADC) of five main metabolites in the human brain at 3T with PRESS and STEAM, avoiding measurement biases because of cross-terms. Cross-terms arise from interactions between slice-selection and spoiler gradients in the localized spectroscopy sequence and the diffus...

journal_title：Magnetic resonance in medicine

authors： Deelchand DK,Auerbach EJ,Marjańska M

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:To develop a strategy for training a physics-guided MRI reconstruction neural network without a database of fully sampled data sets. METHODS:Self-supervised learning via data undersampling (SSDU) for physics-guided deep learning reconstruction partitions available measurements into two disjoint sets, one of wh...

journal_title：Magnetic resonance in medicine

authors： Yaman B,Hosseini SAH,Moeller S,Ellermann J,Uğurbil K,Akçakaya M

更新日期：2020-12-01 00:00:00

abstract：PURPOSE:Previous work has evaluated the quality of different analytic methods for extracting relaxation times from magnitude imaging data exhibiting Rician noise. However, biexponential analysis of relaxation in tissue, including cartilage, and materials is of increasing interest. We, therefore, analyzed biexponential ...

journal_title：Magnetic resonance in medicine

authors： Bouhrara M,Reiter DA,Celik H,Bonny JM,Lukas V,Fishbein KW,Spencer RG

更新日期：2015-01-01 00:00:00

abstract：:It has been suggested that orientational changes in the collagen network of articular cartilage account for the depthwise T2 anisotropy of MRI through the magic angle effect. To investigate the relationship between laminar T2 appearance and collagen organization (anisotropy), bovine osteochondral plugs (N = 9) were T2...

journal_title：Magnetic resonance in medicine

authors： Nieminen MT,Rieppo J,Töyräs J,Hakumäki JM,Silvennoinen J,Hyttinen MM,Helminen HJ,Jurvelin JS

更新日期：2001-09-01 00:00:00

abstract：:Fe(III)meso-tetra(4-sulfonatophenyl)porphine (Fe-TPPS4) has been investigated as a potential pH-sensitive nuclear magnetic resonance (NMR) proton image contrast agent. Relaxation rates (1/T1 and 1/T2) of water protons were measured as a function of pH and concentration of Fe-TPPS4 in phosphate-buffered isotonic saline...

journal_title：Magnetic resonance in medicine

authors： Helpern JA,Curtis JC,Hearshen D,Smith MB,Welch KM

更新日期：1987-09-01 00:00:00

abstract：:A reproducibility study of proton MR spectroscopic imaging ((1)H-MRSI) of the human brain was conducted to evaluate the reliability of an automated 3D in vivo spectroscopic imaging acquisition and associated quantification algorithm. A PRESS-based pulse sequence was implemented using dualband spectral-spatial RF pulse...

journal_title：Magnetic resonance in medicine

authors： Gu M,Kim DH,Mayer D,Sullivan EV,Pfefferbaum A,Spielman DM

更新日期：2008-09-01 00:00:00

abstract：:ECG-gated cardiac MRI in the mouse is hindered by many technical difficulties in ECG signal recording inside static and variable high magnetic scanner fields. The present study proposes an alternative robust method of acquiring auto-gated cardiac and respiratory cine images in mouse heart. In our approach, a motion sy...

journal_title：Magnetic resonance in medicine

authors： Hiba B,Richard N,Janier M,Croisille P

更新日期：2006-03-01 00:00:00

abstract：PURPOSE:Reliable monitoring of tissue nicotinamide adenine dinucleotide (NAD+ ) concentration may provide insights on its roles in normal and pathological aging. In the present study, we report a 1 H MRS pulse sequence for the in vivo, localized 1 H MRS detection of NAD+ from the human brain. METHODS:Studies were carr...

journal_title：Magnetic resonance in medicine

authors： Bagga P,Hariharan H,Wilson NE,Beer JC,Shinohara RT,Elliott MA,Baur JA,Marincola FM,Witschey WR,Haris M,Detre JA,Reddy R

更新日期：2020-03-01 00:00:00

abstract：:Homogeneous soft tissue, as regards its magnetic relaxation properties, is well-modeled by solutions of cross-linked protein (see Koenig and Brown, Prog. NMR Spectr. 22, 487 (1991)). Interactions at the solute-solvent interface alter the hydrodynamics of solvent water, and also couple the solute and solvent proton Zee...

journal_title：Magnetic resonance in medicine

authors： Koenig SH,Brown RD 3rd

更新日期：1993-12-01 00:00:00

abstract：:The potential of quantitative parameter images of the relaxation times T1 and T2, the proton density rho and the apparent diffusion coefficient (ADC) to characterize three different experimental rat brain tumors (F98 glioma, RN6 Schwannoma, and E376 neuroblastoma) was studied. All parameter values, as determined in hi...

journal_title：Magnetic resonance in medicine

authors： Eis M,Els T,Hoehn-Berlage M

更新日期：1995-12-01 00:00:00

abstract：:Precise relaxation time (RT) measurements have been made, with a standard deviation of 3% for T1 and T2 in white matter in normal volunteers. This sets an upper limit to the instrumental random errors (imprecision). Achieving this precision requires careful adjustment and use of the imager. The wide variation in RTs s...

journal_title：Magnetic resonance in medicine

authors： Miller DH,Johnson G,Tofts PS,MacManus D,McDonald WI

更新日期：1989-09-01 00:00:00

abstract：:To understand whether the NO-dependent vasodilator L-arginine was effective upon a chronically hypertensive cerebral capillary endothelium, dynamic susceptibility contrast MRI was used to measure the relative cerebral blood volume (rCBV) changes in nonischemic spontaneously hypertensive rats (SHRs). rCBV was measured ...

journal_title：Magnetic resonance in medicine

authors： Caramia F,Yoshida T,Hamberg LM,Huang Z,Hunter G,Wanke I,Zaharchuk G,Moskowitz MA,Rosen BR

更新日期：1998-01-01 00:00:00

abstract：:For time-resolved background-subtracted contrast-enhanced magnetic resonance angiography, the bright and sparse arterial signal allows unique identification of contrast bolus arrival in the arteries. This article presents an automatic filtering algorithm using such arterial characterization for selecting arterial phas...

journal_title：Magnetic resonance in medicine

authors： Kim J,Prince MR,Zabih R,Bezanson J,Watts R,Erel HE,Wang Y

更新日期：2002-12-01 00:00:00

abstract：PURPOSE:We propose a constrained optimization approach for designing parallel transmit (pTx) pulses satisfying all regulatory and hardware limits. We study the trade-offs between excitation accuracy, local and global specific absorption rate (SAR), and maximum and average power for small flip-angle pTx (eight channels)...

journal_title：Magnetic resonance in medicine

authors： Guérin B,Gebhardt M,Cauley S,Adalsteinsson E,Wald LL

更新日期：2014-04-01 00:00:00

abstract：:Accurate quantification of myocardial perfusion remains challenging due to saturation of the arterial input function at high contrast concentrations. A method for estimating the arterial input function directly from tissue curves in the myocardium that avoids these difficulties is presented. In this constrained altern...

journal_title：Magnetic resonance in medicine

authors： Fluckiger JU,Schabel MC,DiBella EV

更新日期：2011-08-01 00:00:00

abstract：:MRS has considerable potential for the measurement of drug pharmacokinetics in vivo. In this study single- and double-resonance (31)P MRS was used to investigate the biodistribution, pharmacokinetics, and metabolism of ifosfamide following administration of 500 mg/kg ifosfamide in guinea pigs. (1)H-decoupling was foun...

journal_title：Magnetic resonance in medicine

authors： Mancini L,Payne GS,Dzik-Jurasz AS,Leach MO

更新日期：2003-08-01 00:00:00

abstract：:This study presents the detection of [2-(13)C]glucose metabolism in the carboxylic/amide region in the human brain, and demonstrates that the cerebral metabolism of [2-(13)C]glucose can be studied in human subjects in the presence of severe hardware constraints of widely available 3 T clinical scanners and with low-po...

journal_title：Magnetic resonance in medicine

authors： Li S,Zhang Y,Wang S,Yang J,Ferraris Araneta M,Farris A,Johnson C,Fox S,Innis R,Shen J

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:To evaluate proton density fat fraction (PDFF) and R2* as markers of bone marrow composition and structure in inflamed bone in patients with spondyloarthritis. METHODS:Phantoms containing fat, water, and trabecular bone were constructed with proton density fat fraction (PDFF) and bone mineral density (BMD) val...

journal_title：Magnetic resonance in medicine

authors： Bray TJP,Bainbridge A,Punwani S,Ioannou Y,Hall-Craggs MA

更新日期：2018-02-01 00:00:00

abstract：:A method is described for multislice imaging by means of rf pulses which contain a multifrequency excitation spectrum. These pulses label each slice by an individual signal phase and allow the separation of the signals from all the slices by subsequent add/subtract procedures. The image sensitivity corresponds to the ...

journal_title：Magnetic resonance in medicine

authors： Müller S

更新日期：1988-03-01 00:00:00

abstract：PURPOSE:To examine the detection sensitivity for the rapidly exchanging hydroxyl protons of D-glucose using the recently developed on-resonance variable delay multi-pulse (onVDMP) chemical exchange saturation transfer (CEST) technique. METHODS:The onVDMP method was applied for the detection of water signal changes upo...

journal_title：Magnetic resonance in medicine

authors： Xu X,Xu J,Chan KWY,Liu J,Liu H,Li Y,Chen L,Liu G,van Zijl PCM

更新日期：2019-01-01 00:00:00

abstract：:Gadobutrol (Gd-Bt; Gadovist(R), Schering AG) is a 1-M Gadolinium (Gd)-based contrast agent. Its higher Gd concentration allows for reduction of injection volumes in first pass contrast-enhanced MR angiography (CE-MRA) and should increase bolus sharpness and image quality. However, ambivalent results were reported. In ...

journal_title：Magnetic resonance in medicine

authors： Stalder AF,Elverfeldt DV,Paul D,Hennig J,Markl M

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:This study evaluates biochemical imbalances in a rat model that reflects dysfunctional pathways in migraine. The high sensitivity and spectral dispersion available to 1 H MRS at 21.1 T expands metabolic profiling in this migraine model to include lactate (Lac), taurine (Tau), aspartate, and Gly-a mixture of gly...

journal_title：Magnetic resonance in medicine

authors： Abad N,Rosenberg JT,Roussel T,Grice DC,Harrington MG,Grant SC

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To evaluate the role of true diffusion and flow-related pseudodiffusion in cerebral blood flow (CBF) quantification using arterial spin labeling (ASL) with single-shot or segmented 3D gradient and spin echo (GRASE) readouts. THEORY:The extended phase graph (EPG) algorithm, originally designed to model the effe...

journal_title：Magnetic resonance in medicine

authors： He X,Wengler K,Schweitzer ME

更新日期：2018-08-01 00:00:00

abstract：:The application of spectroscopy techniques to the study of normal and pathological tissue is currently limited by the difficulties of acquiring precisely localized spectra and analyzing the resulting, relatively low signal-to-noise data. Interpretation of multivoxel spectroscopy data is greatly facilitated by estimati...

journal_title：Magnetic resonance in medicine

authors： Nelson SJ,Vigneron DB,Brown TR

更新日期：1992-05-01 00:00:00

abstract：:The dependence of 1/T1 on the magnetic field strength (the relaxation dispersion) has been measured at 37 degrees C on autopsy samples of human brain gray and white matter at field strengths corresponding to proton Larmor frequencies between 10 kHz and 50 MHz (0.0002-1.2 T). Additional measurements of 1/T1 and 1/T2 ha...

journal_title：Magnetic resonance in medicine

authors： Fischer HW,Rinck PA,Van Haverbeke Y,Muller RN

更新日期：1990-11-01 00:00:00