Ifosfamide pharmacokinetics and hepatobiliary uptake in vivo investigated using single- and double-resonance 31P MRS.

abstract：:Volume-localized proton NMR spectroscopy was used to estimate bone marrow cellularity in the posterior iliac crests of patients undergoing treatment with hematopoietic growth factors for a variety of hematologic and neoplastic disorders. Twelve patients were accrued, six of whom were studied more than once, yielding a...

journal_title：Magnetic resonance in medicine

authors： Ballon D,Jakubowski A,Gabrilove J,Graham MC,Zakowski M,Sheridan C,Koutcher JA

更新日期：1991-05-01 00:00:00

abstract：:This work presents a method that allows for the assessment of 3D murine myocardial motion in vivo at microscopic resolution. Phase-contrast (PC) magnetic resonance imaging (MRI) at 17.6 T was applied to map myocardial motion in healthy mice along three gradient directions. High-resolution velocity maps were acquired a...

journal_title：Magnetic resonance in medicine

authors： Herold V,Mörchel P,Faber C,Rommel E,Haase A,Jakob PM

更新日期：2006-05-01 00:00:00

abstract：:T2 relaxation time is a promising MRI parameter for the detection of cartilage degeneration in osteoarthritis. However, the accuracy and precision of the measured T2 may be substantially impaired by the low signal-to-noise ratio of images available from clinical examinations. The purpose of this work was to assess the...

journal_title：Magnetic resonance in medicine

authors： Raya JG,Dietrich O,Horng A,Weber J,Reiser MF,Glaser C

更新日期：2010-01-01 00:00:00

abstract：:When developing new techniques for NMR imaging and in vivo spectroscopy it is a major advantage to be able to calculate the magnetization slice profiles, at any point during a pulse sequence in the presence of a field gradient. While this has frequently been done by treating the problem as a number of discrete resonan...

journal_title：Magnetic resonance in medicine

authors： Bulsing JM,Galloway GJ,Brereton IM,Doddrell DM

更新日期：1987-11-01 00:00:00

abstract：PURPOSE:The use of electromagnetic (EM) modeling is critical for specific absorption rate (SAR) characterization in parallel transmission MRI. Radiofrequency arrays that include decoupling networks can be difficult to characterize accurately in simulation. A practical method of simplifying modeling is to exclude the de...

journal_title：Magnetic resonance in medicine

authors： Beqiri A,Hand JW,Hajnal JV,Malik SJ

更新日期：2015-11-01 00:00:00

abstract：:Leakage of Gd-DTPA through a defective blood-brain barrier is measured quantitatively using dynamic MRI scanning, in which repeated scans are made after a bolus injection. Image registration artifacts are minimized; a dose of 0.1 mM/kg and an IR sequence enable enhancement to be measured quantitatively. The triexponen...

journal_title：Magnetic resonance in medicine

authors： Tofts PS,Kermode AG

更新日期：1991-02-01 00:00:00

abstract：PURPOSE:To investigate four-dimensional flow denoising using the divergence-free wavelet (DFW) transform and compare its performance with existing techniques. THEORY AND METHODS:DFW is a vector-wavelet that provides a sparse representation of flow in a generally divergence-free field and can be used to enforce "soft" ...

journal_title：Magnetic resonance in medicine

authors： Ong F,Uecker M,Tariq U,Hsiao A,Alley MT,Vasanawala SS,Lustig M

更新日期：2015-02-01 00:00:00

abstract：:For protons diffusing among a system of magnetic particles, the process by which initial phase coherence is lost depends substantially on particle size. In this article, evidence for three dephasing mechanisms is presented: an incremental process at small particle sizes (motional averaging regime), a discrete process ...

journal_title：Magnetic resonance in medicine

authors： de Haan HW

更新日期：2011-12-01 00:00:00

abstract：:A novel multislice B₁-mapping method dubbed dual refocusing echo acquisition mode is proposed, able to cover the whole transmit coil volume in only one second, which is more than an order of magnitude faster than established approaches. The dual refocusing echo acquisition mode technique employs a stimulated echo acqu...

journal_title：Magnetic resonance in medicine

authors： Nehrke K,Börnert P

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:To develop an analytically based algorithm for rapid optimization of the local radiofrequency magnetic (B1+) field intensity for a given radiofrequency power through a transmit array. The analytical nature of the method will yield insight to optimization requirements and provides a valuable reference for numeri...

journal_title：Magnetic resonance in medicine

authors： Carluccio G,Collins CM,Erricolo D

更新日期：2014-01-01 00:00:00

abstract：:A new method for efficiently processing MRS data acquired with phased-array coils is presented. The method consists of performing phase compensation (i.e., redefining the signal phase relative to a common reference) of the signals in the time domain prior to combining the signals. The resulting spectra are equivalent ...

journal_title：Magnetic resonance in medicine

authors： Brown MA

更新日期：2004-11-01 00:00:00

abstract：PURPOSE:Gradient imperfections remain a challenge in MRI, especially for sequences relying on long imaging readouts. This work aims to explore image reconstruction based on k-space trajectories predicted by an impulse response model of the gradient system. THEORY AND METHODS:Gradient characterization was performed twi...

journal_title：Magnetic resonance in medicine

authors： Vannesjo SJ,Graedel NN,Kasper L,Gross S,Busch J,Haeberlin M,Barmet C,Pruessmann KP

更新日期：2016-07-01 00:00:00

abstract：:Chemical exchange saturation transfer (CEST), arterial spin labeling (ASL), and magnetization transfer contrast (MTC) methods generate different contrasts for MRI. However, they share many similarities in terms of pulse sequences and mechanistic principles. They all use RF pulse preparation schemes to label the longit...

journal_title：Magnetic resonance in medicine

authors： Knutsson L,Xu J,Ahlgren A,van Zijl PCM

更新日期：2018-10-01 00:00:00

abstract：PURPOSE:To obtain multicontrast images including fat-suppressed contrast image, a novel multicontrast imaging method using an SSFP sequence with alternating RF flip angles is proposed. METHODS:The proposed method uses the balanced SSFP sequence with 2 flip angles. In general, the conventional balanced SSFP sequence ha...

journal_title：Magnetic resonance in medicine

authors： Kim J,Seo H,So S,Park H

更新日期：2018-10-01 00:00:00

abstract：:Continuous arterial spin labeling (CASL) was used to obtain an index of cerebral blood flow (ICBF) in the normal mouse brain and in an orthotopic mouse model of human U87 high-grade glioma at 8.5 T. Under the assumption of a constant tissue:blood partition coefficient for water in different tissues, the mean ICBF (n =...

journal_title：Magnetic resonance in medicine

authors： Sun Y,Schmidt NO,Schmidt K,Doshi S,Rubin JB,Mulkern RV,Carroll R,Ziu M,Erkmen K,Poussaint TY,Black P,Albert M,Burstein D,Kieran MW

更新日期：2004-05-01 00:00:00

abstract：:Cerebral blood volume changes with arterial carbon dioxide were monitored by proton T1-weighted MR images following administration of the intravascular contrast agent Gd-DTPA labeled with human serum albumin. Without MR contrast, no significant image intensity changes were observed with PaCO2. Following contrast, regi...

journal_title：Magnetic resonance in medicine

authors： Moseley ME,Chew WM,White DL,Kucharczyk J,Litt L,Derugin N,Dupon J,Brasch RC,Norman D

更新日期：1992-01-01 00:00:00

abstract：:Localized 1H NMR homonuclear J editing spectroscopy was used to measure the concentration of 2-pyrrolidinone (PRDN) in the human occipital lobe of five normal and six epileptic subjects taking vigabatrin. PRDN is a lactam cyclization product of gamma-aminobutyric acid (GABA). From a localized volume of 13.5 cm3 in the...

journal_title：Magnetic resonance in medicine

authors： Hyder F,Petroff OA,Mattson RH,Rothman DL

更新日期：1999-05-01 00:00:00

abstract：:Functional MR imaging (fMRI) of activation in the brain is one of the more demanding applications required of an NMR imaging instrument. Since the signal changes in activation imaging are quite small, any instrumental variations can easily compromise the fMRI contrast. The authors describe a simple method for measurin...

journal_title：Magnetic resonance in medicine

authors： Weisskoff RM

更新日期：1996-10-01 00:00:00

abstract：PURPOSE:To investigate the influence of transcytolemmal water exchange on estimates of tissue microstructural parameters derived from diffusion MRI using conventional PGSE and IMPULSED methods. METHODS:Computer simulations were performed to incorporate a broad range of intracellular water life times τin (50-∞ ms), cel...

journal_title：Magnetic resonance in medicine

authors： Li H,Jiang X,Xie J,Gore JC,Xu J

更新日期：2017-06-01 00:00:00

abstract：:The time evolution of water diffusion, perfusion, T1, and T2 is investigated at high magnetic field (8.5 T) following permanent middle cerebral artery occlusion in the rat. Cerebral blood flow maps were obtained using arterial spin tagging. Although the quantitative perfusion measurements in ischemic tissue still pose...

journal_title：Magnetic resonance in medicine

authors： Calamante F,Lythgoe MF,Pell GS,Thomas DL,King MD,Busza AL,Sotak CH,Williams SR,Ordidge RJ,Gadian DG

更新日期：1999-03-01 00:00:00

abstract：:In vivo, cardiac-gated, black-blood, and ex vivo magnetic resonance microscopy (MRM) images of the aortic root, and histopathology data were obtained from 12 transgenic and wild-type (WT) mice. MRM was performed using a black-blood imaging spin-echo sequence with upstream and downstream in-flow saturation pulses to ob...

journal_title：Magnetic resonance in medicine

authors： Itskovich VV,Choudhury RP,Aguinaldo JG,Fallon JT,Omerhodzic S,Fisher EA,Fayad ZA

更新日期：2003-02-01 00:00:00

abstract：PURPOSE:To develop a fast three-dimensional (3D) k-space encoding method based on spiral projection imaging (SPI) with an interleaved golden-angle approach and to validate this novel sequence on small animal models. METHODS:A disk-like trajectory, in which each disk contained spirals, was developed. The 3D encoding wa...

journal_title：Magnetic resonance in medicine

authors： Castets CR,Lefrançois W,Wecker D,Ribot EJ,Trotier AJ,Thiaudière E,Franconi JM,Miraux S

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:To systematically evaluate the dependence of intravoxel-incoherent-motion (IVIM) parameters on the b-value threshold separating the perfusion and diffusion compartment, and to implement and test an algorithm for the standardized computation of this threshold. METHODS:Diffusion weighted images of the upper abdo...

journal_title：Magnetic resonance in medicine

authors： Wurnig MC,Donati OF,Ulbrich E,Filli L,Kenkel D,Thoeny HC,Boss A

更新日期：2015-11-01 00:00:00

abstract：:In this study, a spin- and gradient-echo echo-planar imaging (SAGE EPI) MRI pulse sequence is presented that allows simultaneous measurements of gradient-echo and spin-echo dynamic susceptibility-contrast perfusion-weighted imaging data. Following signal excitation, five readout trains were acquired using spin- and gr...

journal_title：Magnetic resonance in medicine

authors： Schmiedeskamp H,Straka M,Newbould RD,Zaharchuk G,Andre JB,Olivot JM,Moseley ME,Albers GW,Bammer R

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:To characterize and optimize 19 F MRI for different perfluorocarbons (PFCs) at 3T and quantify the loss of acquisition efficiency as a function of different temperature and cellular conditions. METHODS:The T1 and T2 relaxation times of the commonly used PFCs perfluoropolyether (PFPE), perfluoro-15-crown-5-ethe...

journal_title：Magnetic resonance in medicine

authors： Colotti R,Bastiaansen JAM,Wilson A,Flögel U,Gonzales C,Schwitter J,Stuber M,van Heeswijk RB

更新日期：2017-06-01 00:00:00

abstract：:The assessment of myocardial fibrosis and extracellular volume requires accurate estimation of myocardial T1 s. While image acquisition using the modified Look-Locker inversion recovery technique is clinically feasible for myocardial T1 mapping, respiratory motion can limit its applicability. Moreover, the conventiona...

journal_title：Magnetic resonance in medicine

authors： Xue H,Greiser A,Zuehlsdorff S,Jolly MP,Guehring J,Arai AE,Kellman P

更新日期：2013-05-01 00:00:00

abstract：:The investigation of flow behavior in coronary arteries is of great importance for an understanding of heart failure and heart regulation mechanisms. The purpose of the present study was to demonstrate that flow velocity can be quantified in the coronary arteries of the isolated rat heart with high-resolution phase co...

journal_title：Magnetic resonance in medicine

authors： Köhler S,Hiller KH,Jakob PM,Bauer WR,Haase A

更新日期：2003-09-01 00:00:00

abstract：:The intra-individual and inter-individual variations of the global N-acetylaspartate (NAA) concentration were measured in a cohort of five 42+/-5 year-old normal females. The total NAA signal from the whole head was obtained with non-localized non-echo proton spectroscopy (1H-MRS) and converted into absolute mole amou...

journal_title：Magnetic resonance in medicine

authors： Gonen O,Viswanathan AK,Catalaa I,Babb J,Udupa J,Grossman RI

更新日期：1998-11-01 00:00:00

abstract：PURPOSE:To present the results of the first human spinal cord in vivo MRI scans at 9.4T. METHODS:A human brain coil was used to image the human spinal cord at 9.4T. All anatomical images were acquired with a T2 *-weighted gradient-echo sequence. A comparison of the influence of four different B0 shimming routines on t...

journal_title：Magnetic resonance in medicine

authors： Geldschläger O,Bosch D,Avdievich NI,Henning A

更新日期：2021-02-01 00:00:00

abstract：PURPOSE:To evaluate convex gradient optimization (CVX) for increased spatiotemporal resolution and improved accuracy for phase-contrast MRI (PC-MRI). METHODS:A conventional flow-compensated and flow-encoded (FCFE) PC-MRI sequence was compared with a CVX PC-MRI sequence using numerical simulations, flow phantom experim...

journal_title：Magnetic resonance in medicine

authors： Middione MJ,Wu HH,Ennis DB

更新日期：2014-12-01 00:00:00