Combined spin- and gradient-echo perfusion-weighted imaging.

Abstract:

:In this study, a spin- and gradient-echo echo-planar imaging (SAGE EPI) MRI pulse sequence is presented that allows simultaneous measurements of gradient-echo and spin-echo dynamic susceptibility-contrast perfusion-weighted imaging data. Following signal excitation, five readout trains were acquired using spin- and gradient-echo echo-planar imaging, all of them with echo times of less than 100 ms. Contrast agent concentrations in brain tissue were determined based on absolute R2* and R(2) estimates rather than relative changes in the signals of individual echo trains, producing T(1)-independent dynamic susceptibility-contrast perfusion-weighted imaging data. Moreover, this acquisition technique enabled vessel size imaging through the simultaneous quantification of R2* and R(2), without an increase in acquisition time. In this work, the concepts of SAGE EPI pulse sequence and results in stroke and tumor imaging are presented. Overall, SAGE EPI combined the advantages of higher sensitivity to contrast agent passage of gradient-echo perfusion-weighted imaging with better microvascular selectivity of spin-echo perfusion-weighted imaging.

journal_name

Magn Reson Med

authors

Schmiedeskamp H,Straka M,Newbould RD,Zaharchuk G,Andre JB,Olivot JM,Moseley ME,Albers GW,Bammer R

doi

10.1002/mrm.23195

subject

Has Abstract

pub_date

2012-07-01 00:00:00

pages

30-40

issue

1

eissn

0740-3194

issn

1522-2594

journal_volume

68

pub_type

杂志文章
  • A new approach to autocalibrated dynamic parallel imaging based on the Karhunen-Loeve transform: KL-TSENSE and KL-TGRAPPA.

    abstract::TSENSE and TGRAPPA are autocalibrated parallel imaging techniques that can improve the temporal resolution and/or spatial resolution in dynamic magnetic resonance imaging applications. In its original form, TSENSE uses temporal low-pass filtering of the undersampled frames to create the sensitivity map. TGRAPPA uses a...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22766

    authors: Ding Y,Chung YC,Jekic M,Simonetti OP

    更新日期:2011-06-01 00:00:00

  • Wavelet-space correlation imaging for high-speed MRI without motion monitoring or data segmentation.

    abstract:PURPOSE:This study aims to (i) develop a new high-speed MRI approach by implementing correlation imaging in wavelet-space, and (ii) demonstrate the ability of wavelet-space correlation imaging to image human anatomy with involuntary or physiological motion. METHODS:Correlation imaging is a high-speed MRI framework in ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25546

    authors: Li Y,Wang H,Tkach J,Roach D,Woods J,Dumoulin C

    更新日期:2015-12-01 00:00:00

  • Modification of embolic-PVA particles with MR contrast agents.

    abstract::We report the synthesis and characterization of polyvinyl alcohol (PVA) embolic particles modified with a clinically approved magnetic resonance (MR) contrast agent. PVA particles are used during transcatheter arterial embolization (TAE) procedures and this minimally invasive technique is a widely employed treatment f...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21518

    authors: Cilliers R,Song Y,Kohlmeir EK,Larson AC,Omary RA,Meade TJ

    更新日期:2008-04-01 00:00:00

  • Cerebrospinal fluid pulse wave velocity measurements: In vitro and in vivo evaluation of a novel multiband cine phase-contrast MRI sequence.

    abstract:PURPOSE:Intracranial and intraspinal compliance are parameters of interest in the diagnosis and prediction of treatment outcome in patients with normal pressure hydrocephalus and other forms of communicating hydrocephalus. A noninvasive method to estimate the spinal cerebrospinal fluid (CSF) pulse wave velocity (PWV) a...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.28430

    authors: Sonnabend K,Brinker G,Maintz D,Bunck AC,Weiss K

    更新日期:2021-01-01 00:00:00

  • Phosphonate-modified GdDTPA complexes. I. NMRD study of the solution behavior of new tissue-specific contrast agents.

    abstract::NMRD profiles, the magnetic field dependence of the water proton longitudinal relaxation rates, have been acquired for two new diphosphonate-modified GdDTPA complexes currently under evaluation as relaxation agents for the MRI detection of soft-tissue calcifications. Fresh dilute solutions show profiles identical to t...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910170118

    authors: Adzamli IK,Blau M

    更新日期:1991-01-01 00:00:00

  • Passive tracking of catheters and guidewires by contrast-enhanced MR fluoroscopy.

    abstract::Passive MR tracking of catheters and guidewires is usually done by dynamically imaging a single thick slab, subtracting a baseline image, and combining the result with a previously acquired MR angiogram. In the in vitro and in vivo experiments reported here, it is demonstrated that this approach may be greatly simplif...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/1522-2594(200101)45:1<17::aid-mrm1003>3.0.

    authors: Bakker CJ,Bos C,Weinmann HJ

    更新日期:2001-01-01 00:00:00

  • Fast group matching for MR fingerprinting reconstruction.

    abstract:PURPOSE:MR fingerprinting (MRF) is a technique for quantitative tissue mapping using pseudorandom measurements. To estimate tissue properties such as T1 , T2 , proton density, and B0 , the rapidly acquired data are compared against a large dictionary of Bloch simulations. This matching process can be a very computation...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25439

    authors: Cauley SF,Setsompop K,Ma D,Jiang Y,Ye H,Adalsteinsson E,Griswold MA,Wald LL

    更新日期:2015-08-01 00:00:00

  • Design of spectral-spatial phase prewinding pulses and their use in small-tip fast recovery steady-state imaging.

    abstract:PURPOSE:Spectrally selective "prewinding" radiofrequency pulses can counteract B0 inhomogeneity in steady-state sequences, but can only prephase a limited range of off-resonance. We propose spectral-spatial small-tip angle prewinding pulses that increase the off-resonance bandwidth that can be successfully prephased by...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26794

    authors: Williams SN,Nielsen JF,Fessler JA,Noll DC

    更新日期:2018-03-01 00:00:00

  • Unambiguous assignment of the H3S and H3R deuterations of cerebral (2-13C) glutamate by 13C NMR at 18.8 Tesla.

    abstract::We used high-field (13)C NMR (18.8 T) to assign unambiguously the isotopic shifts induced by the deuterium substitutions of the H3(proR) and H3(proS) hydrogens of (2-(13)C) glutamate in extracts of the brain from deuterated animals. Monodeuterated H3R or H3S glutamate diastereoisomers were produced stereospecifically ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22277

    authors: Rodrigues TB,Violante IR,Cerdán S

    更新日期:2010-04-01 00:00:00

  • A hybrid method for more efficient channel-by-channel reconstruction with many channels.

    abstract::In MRI, imaging using receiving coil arrays with a large number of elements is an area of growing interest. With increasing channel numbers for parallel acquisition, longer reconstruction times have become a significant concern. Channel reduction techniques have been proposed to reduce the processing time of channel-b...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.23048

    authors: Huang F,Lin W,Duensing GR,Reykowski A

    更新日期:2012-03-01 00:00:00

  • Two-site reproducibility of cerebellar and brainstem neurochemical profiles with short-echo, single-voxel MRS at 3T.

    abstract:PURPOSE:To determine whether neurochemical concentrations obtained at two MRI sites using clinical 3T scanners can be pooled when a highly optimized, nonvendor short-echo, single-voxel proton MRS pulse sequence is used in conjunction with identical calibration and quantification procedures. METHODS:A modified semi-LAS...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25295

    authors: Deelchand DK,Adanyeguh IM,Emir UE,Nguyen TM,Valabregue R,Henry PG,Mochel F,Öz G

    更新日期:2015-05-01 00:00:00

  • Quantitative measurement of regional lung ventilation using 3He MRI.

    abstract::A new strategy for a quantitative measurement of regional pulmonary ventilation using hyperpolarized helium-3 (3He) MRI has been developed. The method employs the build-up of the signal intensity after a variable number of (3)He breaths. A mathematical model of the signal dynamics is presented, from which the local ve...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10206

    authors: Deninger AJ,Månsson S,Petersson JS,Pettersson G,Magnusson P,Svensson J,Fridlund B,Hansson G,Erjefeldt I,Wollmer P,Golman K

    更新日期:2002-08-01 00:00:00

  • System identification theory in pharmacokinetic modeling of dynamic contrast-enhanced MRI: influence of contrast injection.

    abstract::Optimization of experimental settings of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), like the contrast administration protocol, is of great importance for reliable quantification of the microcirculatory properties, such as the volume transfer-constant K(trans). Using system identification theory an...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21575

    authors: Aerts HJ,van Riel NA,Backes WH

    更新日期:2008-05-01 00:00:00

  • High-order coils as transmitters for NMR imaging.

    abstract::High-order radiofrequency transmitter coils are described that permit, in the context of NMR imaging, a knowledgeable trade-off between coil complexity and the degree of inhomogeneity over a specified volume of space. A mathematical formulation of high-order coils is developed for an axially symmetric polarizing dc fi...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910030108

    authors: Sotgiu A,Hyde JS

    更新日期:1986-02-01 00:00:00

  • NMR visibility studies of N-delta proton of proximal histidine in deoxyhemoglobin in lysed and intact red cells.

    abstract::Recent in vivo 1H MRS studies of muscle oxygen levels by means of myoglobin (Mb) oxygenation have necessitated an investigation of the possible contamination from deoxy-hemoglobin (Hb). To determine the contribution of Hb in these NMR measurements, we studied the NMR visibility of histidyl N-delta proton of Hb in lyse...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910300616

    authors: Wang DJ,Nioka S,Wang Z,Leigh JS,Chance B

    更新日期:1993-12-01 00:00:00

  • Direct reconstruction of MR images from data acquired on a non-Cartesian grid using an equal-phase-line algorithm.

    abstract::The equal-phase line (EPL) algorithm is proposed as a means of allowing rapid Fourier transform (FT) reconstruction of MR image data acquired on a non-Cartesian grid. The pixels on the image are grouped according to their positions. The pixels in a group have the same phase in the complex exponential function -exp[j2p...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10165

    authors: Qian Y,Lin J,Jin D

    更新日期:2002-06-01 00:00:00

  • An analytical solution for the SSFP signal in MRI.

    abstract::Among previous analyses of the steady-state free-precession (SSFP) signal in rapid MRI, one treatment resulted in equations that require the evaluation of infinite binomial series. Here, an analytical solution is derived by a transformation into the power series expansion of the derivative of the inverse sine function...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10410

    authors: Hänicke W,Vogel HU

    更新日期:2003-04-01 00:00:00

  • Real-time cardiovascular MR with spatio-temporal artifact suppression using deep learning-proof of concept in congenital heart disease.

    abstract:PURPOSE:Real-time assessment of ventricular volumes requires high acceleration factors. Residual convolutional neural networks (CNN) have shown potential for removing artifacts caused by data undersampling. In this study, we investigated the ability of CNNs to reconstruct highly accelerated radial real-time data in pat...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27480

    authors: Hauptmann A,Arridge S,Lucka F,Muthurangu V,Steeden JA

    更新日期:2019-02-01 00:00:00

  • 3D compressed sensing for highly accelerated hyperpolarized (13)C MRSI with in vivo applications to transgenic mouse models of cancer.

    abstract::High polarization of nuclear spins in liquid state through hyperpolarized technology utilizing dynamic nuclear polarization has enabled the direct monitoring of (13)C metabolites in vivo at a high signal-to-noise ratio. Acquisition time limitations due to T(1) decay of the hyperpolarized signal require accelerated ima...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22233

    authors: Hu S,Lustig M,Balakrishnan A,Larson PE,Bok R,Kurhanewicz J,Nelson SJ,Goga A,Pauly JM,Vigneron DB

    更新日期:2010-02-01 00:00:00

  • An optimized center-out k-space trajectory for multishot MRI: comparison with spiral and projection reconstruction.

    abstract::A method for collecting MRI data on a set of rotated trajectories that begin at the center of k-space is outlined. It is theoretically slightly faster, slightly less susceptible to off-resonance and motion-induced phase, and produces images with slightly better signal-to-noise ratio than methods using Archimedean spir...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1522-2594(199910)42:4<714::aid-mrm13

    authors: Pipe JG

    更新日期:1999-10-01 00:00:00

  • Dynamic imaging with multiple resolutions along phase-encode and slice-select dimensions.

    abstract::An implementation is reported of an imaging method to obtain MUltiple Resolutions along Phase-encode and Slice-select dimensions (MURPS), which enables dynamic imaging of focal changes using a graded, multiresolution approach. MURPS allows one to trade spatial resolution in part of the volume for improved temporal res...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1126

    authors: Panych LP,Zhao L,Jolesz FA,Mulkern RV

    更新日期:2001-06-01 00:00:00

  • Constrained estimation of the arterial input function for myocardial perfusion cardiovascular magnetic resonance.

    abstract::Accurate quantification of myocardial perfusion remains challenging due to saturation of the arterial input function at high contrast concentrations. A method for estimating the arterial input function directly from tissue curves in the myocardium that avoids these difficulties is presented. In this constrained altern...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22809

    authors: Fluckiger JU,Schabel MC,DiBella EV

    更新日期:2011-08-01 00:00:00

  • Resolution-recovery for EPR imaging of free radical molecules in mice.

    abstract::A method of post-processing to enhance the image resolution of the distribution of free radical molecules obtained with continuous-wave electron paramagnetic resonance (CW-EPR) imaging is reported. The low spatial resolution of EPR imaging, which has created difficulties in biomedical applications, was overcome by the...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22029

    authors: Ikebata Y,Sato-Akaba H,Aoyama T,Fujii H,Itoh K,Hirata H

    更新日期:2009-09-01 00:00:00

  • Human whole-blood (1)H2O longitudinal relaxation with normal and high-relaxivity contrast reagents: influence of trans-cell-membrane water exchange.

    abstract:PURPOSE:Accurate characterization of contrast reagent (CR) longitudinal relaxivity in whole blood is required to predict arterial signal intensity in contrast-enhanced MR angiography (CE-MRA). This study measured the longitudinal relaxation rate constants (R1 ) over a concentration range for non-protein-binding and pro...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25064

    authors: Wilson GJ,Woods M,Springer CS Jr,Bastawrous S,Bhargava P,Maki JH

    更新日期:2014-12-01 00:00:00

  • Generalized matched filtering for time-resolved MR angiography of pulsatile flow.

    abstract::Generating flow-specific images (arteriograms, venograms) with optimal signal-to-noise ratios for time-resolved MR angiography is a conditional maximum problem, and its solutions are generalized matched filters. We have investigated six matched filters, corresponding to all possible combinations of three flow suppress...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910300511

    authors: Wang Y,Weber DM,Korosec FR,Mistretta CA,Grist TM,Swan JS,Turski PA

    更新日期:1993-11-01 00:00:00

  • Dextran-magnetite: a contrast agent for sodium-23 MRI.

    abstract::Dextran-magnetite, a superparamagnetic compound, is a powerful relaxation reagent for sodium. Administered intravenously, it is confined mainly to the vasculature and eliminates the signal from plasma sodium, a significant component of the tissue sodium signal. Applications of dextran-magnetite for in vivo sodium imag...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910080406

    authors: Summers RM,Joseph PM,Renshaw PF,Kundel HL

    更新日期:1988-12-01 00:00:00

  • Model-based mapping of fat unsaturation and chain length by chemical shift imaging--phantom validation and in vivo feasibility.

    abstract::Knowledge about the triglyceride (fat) (1)H spectrum enables quantitative determination of several triglyceride characteristics. This work describes a model-based chemical shift imaging method that separates water and fat signal and provides maps of three triglyceride quantities: fatty acid carbon chain length, unsatu...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24196

    authors: Berglund J,Ahlström H,Kullberg J

    更新日期:2012-12-01 00:00:00

  • On multiple alternating steady states induced by periodic spin phase perturbation waveforms.

    abstract::Direct measurement of neural currents by means of MRI can potentially open a high temporal resolution (10-100 ms) window applicable for monitoring dynamics of neuronal activity without loss of the high spatial resolution afforded by MRI. Previously, we have shown that the alternating balanced steady state imaging affo...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.23105

    authors: Buračas GT,Jung Y,Lee J,Buxton RB,Wong EC,Liu TT

    更新日期:2012-05-01 00:00:00

  • Cardiac transfer function relating energy metabolism to workload in different species as studied with 31P NMR.

    abstract::Cardiac metabolism was studied with 31P NMR in 7 dogs and 4 cats to determine whether animals adapted for different life-styles (stalk and sprint vs endurance running) respond to increased work loads (heart rate X blood pressure product) with different high-energy phosphate kinetics. Hearts were exposed via a left lat...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910040203

    authors: Ligeti L,Osbakken MD,Clark BJ,Schnall M,Bolinger L,Subramanian H,Leigh JS,Chance B

    更新日期:1987-02-01 00:00:00

  • Sources of functional apparent diffusion coefficient changes investigated by diffusion-weighted spin-echo fMRI.

    abstract::The mechanism behind previously observed changes in the apparent diffusion coefficient (ADC) during brain activation is not well understood. Therefore, we investigated the signal source and spatial specificity of functional magnetic resonance imaging (fMRI) ADC changes systematically in the visual cortex of cats using...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21074

    authors: Jin T,Zhao F,Kim SG

    更新日期:2006-12-01 00:00:00