Abstract:
:Dextran-magnetite, a superparamagnetic compound, is a powerful relaxation reagent for sodium. Administered intravenously, it is confined mainly to the vasculature and eliminates the signal from plasma sodium, a significant component of the tissue sodium signal. Applications of dextran-magnetite for in vivo sodium imaging of a normal rat and rats with a tumor and experimentally induced peripheral edema are shown. Our results indicate that dextran-magnetite may be useful for improving tumor detection and for imaging of edema. To our knowledge, this is the first report of a contrast agent suitable for sodium magnetic resonance imaging.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Summers RM,Joseph PM,Renshaw PF,Kundel HLdoi
10.1002/mrm.1910080406subject
Has Abstractpub_date
1988-12-01 00:00:00pages
427-39issue
4eissn
0740-3194issn
1522-2594journal_volume
8pub_type
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journal_title:Magnetic resonance in medicine
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journal_title:Magnetic resonance in medicine
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更新日期:2000-02-01 00:00:00
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更新日期:1999-03-01 00:00:00
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更新日期:2018-05-01 00:00:00
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