Perfusion-based functional magnetic resonance imaging with single-shot RARE and GRASE acquisitions.

abstract：:The multiexponential behavior of the decay curves obtained in vitro by a Carr-Purcell-Meiboom-Gill (CPMG) sequence from spleens and kidneys of mice is analyzed. The mice were inoculated with the acute lymphocytic P388 leukemic cells and treated with the anticancer drug cis-diamminedichloroplatinum(II), cis-Pt. Kidneys...

journal_title：Magnetic resonance in medicine

authors： François A,Van Gerven L,Atassi G,Eisendrath H,Gielen M,Willem R

更新日期：1988-08-01 00:00:00

abstract：:MRS has considerable potential for the measurement of drug pharmacokinetics in vivo. In this study single- and double-resonance (31)P MRS was used to investigate the biodistribution, pharmacokinetics, and metabolism of ifosfamide following administration of 500 mg/kg ifosfamide in guinea pigs. (1)H-decoupling was foun...

journal_title：Magnetic resonance in medicine

authors： Mancini L,Payne GS,Dzik-Jurasz AS,Leach MO

更新日期：2003-08-01 00:00:00

abstract：:We used deuterium magnetic resonance imaging (2H MRI) to visualize water movement in the rabbit eye. Dynamic 2H MRI was obtained every 3.5 min at 2 tesla by FLASH pulse sequence (TR, 300 ms; TE, 10 ms; alpha = 90 degrees) with a slice thickness of 10 mm using a surface coil (4 cm in diameter). After topical administra...

journal_title：Magnetic resonance in medicine

authors： Obata T,Ikehira H,Koga M,Yoshida K,Kimura F,Tateno Y

更新日期：1995-04-01 00:00:00

abstract：:Hyperpolarized (HP) 129Xe can be dissolved in biologically compatible lipid emulsions while maintaining sufficient polarization for in vivo vascular imaging. For xenon in Intralipid 30%, in vitro spectroscopy at 2 T yielded a chemical shift of 197 +/- 1 ppm with reference to xenon gas, a spin-lattice relaxation time T...

journal_title：Magnetic resonance in medicine

authors： Möller HE,Chawla MS,Chen XJ,Driehuys B,Hedlund LW,Wheeler CT,Johnson GA

更新日期：1999-05-01 00:00:00

abstract：PURPOSE:To characterize and optimize 19 F MRI for different perfluorocarbons (PFCs) at 3T and quantify the loss of acquisition efficiency as a function of different temperature and cellular conditions. METHODS:The T1 and T2 relaxation times of the commonly used PFCs perfluoropolyether (PFPE), perfluoro-15-crown-5-ethe...

journal_title：Magnetic resonance in medicine

authors： Colotti R,Bastiaansen JAM,Wilson A,Flögel U,Gonzales C,Schwitter J,Stuber M,van Heeswijk RB

更新日期：2017-06-01 00:00:00

abstract：:The recently developed technique of gradient, high-resolution magic-angle spinning NMR (g-hr-MAS-NMR) spectroscopy was applied to the study of ex vivo human lipoma and liposarcoma tissue. Compared with conventional 1H-NMR, the g-hr-MAS method yielded a large improvement in spectral resolution and permitted the detecti...

journal_title：Magnetic resonance in medicine

authors： Millis KK,Maas WE,Cory DG,Singer S

更新日期：1997-09-01 00:00:00

abstract：:Adipose tissue as well as other depots of fat (triglycerides) are increasingly being recognized as active contributors to the human function and metabolism. In addition to the fat concentration, also the fatty acid chemical composition (FAC) of the triglyceride molecules may play an important part in diseases such as ...

journal_title：Magnetic resonance in medicine

authors： Peterson P,Trinh L,Månsson S

更新日期：2021-01-01 00:00:00

abstract：:In an effort to develop MRI methods for the evaluation of tumor angiogenesis (new blood vessel formation), MRI-derived cerebral blood volume (CBV) information has been compared to histologic measures of microvessel density (MVD). Although MVD is a standard marker of angiogenesis, it is not a direct correlate of the vo...

journal_title：Magnetic resonance in medicine

authors： Pathak AP,Schmainda KM,Ward BD,Linderman JR,Rebro KJ,Greene AS

更新日期：2001-10-01 00:00:00

abstract：:Standard MRI cine exams for the study of cardiac function are segmented over several heartbeats and thus require a breath-hold to minimize breathing motion artifacts, which is a current limitation of this approach. The purpose of this study was to develop a method for the measurement and correction of respiratory moti...

journal_title：Magnetic resonance in medicine

authors： Leung AO,Paterson I,Thompson RB

更新日期：2008-09-01 00:00:00

abstract：:It is shown that the effect of pH changes can be measured in proton NMR spectra through the pH sensitivity of the signal intensities of metabolite protons exchanging with water. To observe this phenomenon, pulse sequences must be used that can sensitively observe these exchangeable protons under physiological conditio...

journal_title：Magnetic resonance in medicine

authors： Mori S,Eleff SM,Pilatus U,Mori N,van Zijl PC

更新日期：1998-07-01 00:00:00

abstract：:The study of lung perfusion in normal and diseased subjects is of great interest to physiologists and physicians. In this work we demonstrate the application of a liquid-phase hyperpolarized (HP) carbon-13 ((13)C) tracer to magnetic resonance imaging (MRI) of the pulmonary vasculature and pulmonary perfusion in a porc...

journal_title：Magnetic resonance in medicine

authors： Ishii M,Emami K,Kadlecek S,Petersson JS,Golman K,Vahdat V,Yu J,Cadman RV,MacDuffie-Woodburn J,Stephen M,Lipson DA,Rizi RR

更新日期：2007-03-01 00:00:00

abstract：:A combined carbogen ultrasmall superparamagnetic iron oxide (USPIO) imaging protocol was developed and applied in vivo in two murine colorectal tumor xenograft models, HCT116 and SW1222, with established disparate vascular morphology, to investigate whether additional information could be extracted from the combinatio...

journal_title：Magnetic resonance in medicine

authors： Burrell JS,Walker-Samuel S,Baker LC,Boult JK,Ryan AJ,Waterton JC,Halliday J,Robinson SP

更新日期：2011-07-01 00:00:00

abstract：:Myocardial MR first-pass perfusion time courses are contaminated by signals from the ventricles (spillover) as a consequence of partial volume effects and motion. An early increase in the signal intensity from the myocardium is an indicator of contamination. This contamination leads to under- or overestimation of perf...

journal_title：Magnetic resonance in medicine

authors： Köstler H,Ritter C,Reiss-Zimmermann M,Beer M,Hahn D,Sandstede J

更新日期：2004-04-01 00:00:00

abstract：:The purpose of this study is (1) to determine the correlation between T(1rho) and T(2) and degenerative grade in intervertebral discs using in vivo 3.0-T MRI, and (2) to determine the association between T(1rho) and T(2) and clinical findings as quantified by the SF-36 Questionnaire and Oswestry Disability Index. Sixt...

journal_title：Magnetic resonance in medicine

authors： Blumenkrantz G,Zuo J,Li X,Kornak J,Link TM,Majumdar S

更新日期：2010-05-01 00:00:00

abstract：:The differential effects of high temperature on 9L rat gliosarcoma cells cultured in two distinctive forms, namely, anchored monolayer cells and multicellular spheroids, were investigated using 31P nuclear magnetic resonance spectroscopy. The critical temperatures resulting in irreversible changes in cellular energeti...

journal_title：Magnetic resonance in medicine

authors： Suzuki N,Kwee IL,Tamas LB,Nakada T

更新日期：1991-06-01 00:00:00

abstract：:The goal of this work was to develop an MRI method for mapping the clearance of interstitial macromolecular plasma proteins after their extravasation from permeable blood vessels. To that end, a well-defined window of exposure to elevated blood levels was generated by inducing rapid clearance of macromolecular contras...

journal_title：Magnetic resonance in medicine

authors： Dafni H,Gilead A,Nevo N,Eilam R,Harmelin A,Neeman M

更新日期：2003-11-01 00:00:00

abstract：:This study investigated the use of dynamic, volumetric MRI to measure 3D skeletal motion. Ten healthy subjects were positioned on a MR-compatible knee loading device and instructed to harmonically flex and extend their knee at 0.5 Hz. The device induced active quadriceps loading with knee flexion, similar to the load ...

journal_title：Magnetic resonance in medicine

authors： Kaiser J,Bradford R,Johnson K,Wieben O,Thelen DG

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To develop a method to correct for geometric distortions in non-Cartesian echo planar imaging using data acquired in a fast prescan. METHODS:Echo planar images were obtained using a non-Cartesian density weighted k-space trajectory. In contrast to linear Cartesian acquisition, distortions arising in non-Cartes...

journal_title：Magnetic resonance in medicine

authors： Zeller M,Müller A,Hahn D,Köstler H

更新日期：2014-03-01 00:00:00

abstract：:The pulse wave velocity (PWV) of aortic blood flow is considered a surrogate for aortic compliance. A new method using phase-contrast (PC)-MRI is presented whereby the spatial and temporal profiles of axial velocity along the descending aorta can be analyzed. Seventeen young healthy volunteers (the YH group), six olde...

journal_title：Magnetic resonance in medicine

authors： Yu HY,Peng HH,Wang JL,Wen CY,Tseng WY

更新日期：2006-10-01 00:00:00

abstract：PURPOSE:To study the utility of fractional calculus in modeling gradient-recalled echo MRI signal decay in the normal human brain. METHODS:We solved analytically the extended time-fractional Bloch equations resulting in five model parameters, namely, the amplitude, relaxation rate, order of the time-fractional derivat...

journal_title：Magnetic resonance in medicine

authors： Qin S,Liu F,Turner IW,Yu Q,Yang Q,Vegh V

更新日期：2017-04-01 00:00:00

abstract：PURPOSE:We report a series of techniques to reliably eliminate artifacts in interleaved echo-planar imaging (EPI) based diffusion-weighted imaging (DWI). METHODS:First, we integrate the previously reported multiplexed sensitivity encoding (MUSE) algorithm with a new adaptive Homodyne partial-Fourier reconstruction alg...

journal_title：Magnetic resonance in medicine

authors： Chang HC,Guhaniyogi S,Chen NK

更新日期：2015-05-01 00:00:00

abstract：:The goal of this study was to measure the interindividual reproducibility of glutamate quantification in 1.5-T (1)H MRS of human brains. To determine the effective echo time (TE) for glutamate quantification, spectra from a phantom and 12 participants were obtained with TE = 30, 35, 40, and 144 ms (repetition time (TR...

journal_title：Magnetic resonance in medicine

authors： Jang DP,Lee JM,Lee E,Park S,Kim JJ,Namkoong K,Yoon KJ,Kim IY,Kim SI

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:Assessing the functionality of muscle fibers is essential to monitor both pathological and physiological processes. Here, we present a new method for accurate, quantitative measurement of muscle contraction with magnetic resonance imaging (MRI) using an electrical muscle stimulator (EMS), hence allowing the dir...

journal_title：Magnetic resonance in medicine

authors： Deligianni X,Pansini M,Garcia M,Hirschmann A,Schmidt-Trucksäss A,Bieri O,Santini F

更新日期：2017-02-01 00:00:00

abstract：:A single slice of z-magnetization is used to generate high-speed images. The slice selection step is achieved using two sin-sinc pulses. This procedure eliminates the need for continual slice gradient reversal, a requirement for the FLASH technique. The RAPID imaging method has less inherent T1 and/or T2 dependence th...

journal_title：Magnetic resonance in medicine

authors： Brooks WM,Brereton IM,Doddrell DM

更新日期：1987-08-01 00:00:00

abstract：:We developed a quantitative magnetic resonance imaging method to permit a rapid assessment of brain water content during osmotic brain edema produced by intraperitoneal (ip) injection of distilled water. Fifteen minutes after water injection, the normalized mean image intensity (MIn) from a spin-echo pulse sequence (T...

journal_title：Magnetic resonance in medicine

authors： Olson JE,Katz-Stein A,Reo NV,Jolesz FA

更新日期：1992-03-01 00:00:00

abstract：:A computer simulation program capable of demonstrating various artifacts, such as image distortion caused by metallic implants in MR imaging, is presented. The structure of the program allows for the implementation of various imaging situations as long as spins only experience weak interaction, i.e., the Bloch equatio...

journal_title：Magnetic resonance in medicine

authors： Olsson MB,Wirestam R,Persson BR

更新日期：1995-10-01 00:00:00

abstract：:In spin echo imaging, magnetization is assigned to a location defined by its frequency of rotation. In the presence of a static magnetic field inhomogeneity, however, this location does not correspond to the true location of the magnetization. This paper describes a magnetic resonance imaging technique called phase co...

journal_title：Magnetic resonance in medicine

authors： Kim JK,Plewes DB,Henkelman RM

更新日期：1995-04-01 00:00:00

abstract：:Chemical shift-based multipoint water-fat separation methods have been applied in balanced steady-state free precession (bSSFP) sequences because of the high signal-to-noise-ratio (SNR) attainable. In this approach the echo formation is approximated to occur concurrently for both water and fat at an echo time (TE) equ...

journal_title：Magnetic resonance in medicine

authors： Kim H,Pinus AB,Wang J,Murphy PS,Constable RT

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:To develop a pulsed CEST magnetization-transfer method for rapidly acquiring relayed nuclear Overhauser enhancement (rNOE)-weighted images with magnetic transfer contrast (MTC) suppression at clinical field strength (3 T). METHODS:Using a pulsed CEST magnetization-transfer method with low saturation powers (B1...

journal_title：Magnetic resonance in medicine

authors： Huang J,Han X,Chen L,Xu X,Xu J,Chan KWY

更新日期：2021-01-01 00:00:00

abstract：:A new method is presented for the quantitative determination of regional blood volumes in vivo. It is based on rapid quantitative T1 mapping by Snapshot FLASH MRI combined with the injection of an intravascular MR contrast agent. Regional blood volumes in four different tissues of the rat (skeletal muscle, heart, live...

journal_title：Magnetic resonance in medicine

authors： Schwarzbauer C,Syha J,Haase A

更新日期：1993-05-01 00:00:00