Abstract:
PURPOSE:Real-time assessment of ventricular volumes requires high acceleration factors. Residual convolutional neural networks (CNN) have shown potential for removing artifacts caused by data undersampling. In this study, we investigated the ability of CNNs to reconstruct highly accelerated radial real-time data in patients with congenital heart disease (CHD). METHODS:A 3D (2D plus time) CNN architecture was developed and trained using synthetic training data created from previously acquired breath hold cine images from 250 CHD patients. The trained CNN was then used to reconstruct actual real-time, tiny golden angle (tGA) radial SSFP data (13 × undersampled) acquired in 10 new patients with CHD. The same real-time data was also reconstructed with compressed sensing (CS) to compare image quality and reconstruction time. Ventricular volume measurements made using both the CNN and CS reconstructed images were compared to reference standard breath hold data. RESULTS:It was feasible to train a CNN to remove artifact from highly undersampled radial real-time data. The overall reconstruction time with the CNN (including creation of aliased images) was shown to be >5 × faster than the CS reconstruction. In addition, the image quality and accuracy of biventricular volumes measured from the CNN reconstructed images were superior to the CS reconstructions. CONCLUSION:This article has demonstrated the potential for the use of a CNN for reconstruction of real-time radial data within the clinical setting. Clinical measures of ventricular volumes using real-time data with CNN reconstruction are not statistically significantly different from gold-standard, cardiac-gated, breath-hold techniques.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Hauptmann A,Arridge S,Lucka F,Muthurangu V,Steeden JAdoi
10.1002/mrm.27480subject
Has Abstractpub_date
2019-02-01 00:00:00pages
1143-1156issue
2eissn
0740-3194issn
1522-2594journal_volume
81pub_type
杂志文章abstract::Detre et al. (Magn. Reson. Med. 23, 37-45 (1992)) and Zhang et al., (Magn. Reson. Med. 25, 362 (1992)) have recently demonstrated a technique for the measurement of regional cerebral blood flow (rCBF) based on the continuous saturation (or inversion) of the arterial blood supply to the brain in rats at 4.7 T. In the w...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910310208
更新日期:1994-02-01 00:00:00
abstract:PURPOSE:To develop and validate a data processing technique that allows phase-contrast MRI-based 4D flow imaging of the aortic valve in a single breath-hold. THEORY AND METHODS:To regularize the ill-posed inverse problem, we extend a recently proposed 2D phase-contrast MRI method to 4D flow imaging. Adopting an empiri...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27386
更新日期:2019-02-01 00:00:00
abstract:PURPOSE:To develop a strategy for training a physics-guided MRI reconstruction neural network without a database of fully sampled data sets. METHODS:Self-supervised learning via data undersampling (SSDU) for physics-guided deep learning reconstruction partitions available measurements into two disjoint sets, one of wh...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.28378
更新日期:2020-12-01 00:00:00
abstract::The purpose of the study was to test a newly developed, MR-compatible, liquid nitrogen-cooled cryoprobe. The probe has an outer diameter of 3.5 mm and was specifically developed for percutaneous, MR-guided, interstitial cryotherapy. The probe was inserted percutaneously into the livers of 10 rabbits. The cryotherapy p...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910390304
更新日期:1998-03-01 00:00:00
abstract::Prepolarized MRI uses pulsed magnetic fields to produce MR images by polarizing the sample at one field strength (approximately 0.5 T) before imaging at a much lower field (approximately 50 mT). Contrast reflecting the T(1) of the sample at an intermediate field strength is achieved by polarizing the sample and then a...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.20910
更新日期:2006-06-01 00:00:00
abstract::Golgi impregnation is unique in its ability to display the dendritic trees and axons of large numbers of individual neurons by histology. Here we apply magnetic resonance microscopy to visualize the neuroanatomy of animal models by combining histologic fixation chemistry with paramagnetic contrast agents. Although the...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22322
更新日期:2010-05-01 00:00:00
abstract::Imaging delayed hyperenhancement of myocardial infarction is most commonly performed using an inversion recovery (IR) prepared 2D breathhold segmented k-space gradient echo (FGRE) sequence. Since only one slice is acquired per breathhold in this technique, 12-16 successive breathholds are required for complete anatomi...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.20061
更新日期:2004-05-01 00:00:00
abstract::As the static magnetic field strength used in human magnetic resonance imaging increases, the wavelength of the corresponding radiofrequency field becomes comparable to the dimensions of the coil and volume of interest. The dielectric resonance effects that arise in this full wavelength regime may be partially compens...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.20583
更新日期:2005-08-01 00:00:00
abstract::Any number of coils can in principle be used simultaneously and independently in magnetic resonance imaging if the mutual inductances are sufficiently small. Surface coils and head or body coils have equal sensitivity at some crossover depth of the order of 6 to 10 cm. Using a 7.5-cm-diameter surface coil that was int...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910060212
更新日期:1988-02-01 00:00:00
abstract:PURPOSE:To introduce a new outer volume suppression (OVS) technique that uses a single pulse and rotating gradients to accomplish frequency-swept excitation. This new technique, which is called gradient rotating outer volume excitation (GROOVE), produces a circular or elliptical suppression band rather than suppressing...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25101
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:The clinical potential of the diffusion imaging-based analysis of fine brain structures such as fornix or cingulum is high due to the central role of these structures in psychiatric diseases. However, the quantification of diffusion parameters in fine structures is especially prone to partial volume effects (PV...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24774
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:Applications of dynamic shimming require high field fidelity, and characterizing the shim field dynamics is therefore necessary. Modeling the system as linear and time-invariant, the purpose of this work was to measure the impulse response function with optimal sensitivity. THEORY AND METHODS:Frequency-swept p...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24934
更新日期:2014-08-01 00:00:00
abstract::MRI of myocardial perfusion observed with an extracellular contrast agent has proven valuable for the detection of coronary artery disease. During contrast enhancement transient dark rim artifacts are sometimes visible, complicating diagnosis and quantification. In this work a quantification of the frequency offsets c...
journal_title:Magnetic resonance in medicine
pub_type: 临床试验,杂志文章
doi:10.1002/mrm.21723
更新日期:2008-10-01 00:00:00
abstract::Multislice, two-dimensional phosphorus 31 spectroscopic imaging (SI) of human brain was performed in 15 normal volunteers on a 3-Tesla magnetic resonance system. Images of free magnesium concentrations and pH as well as phosphoesters, inorganic phosphate, phosphocreatine, and adenosine triphosphate (ATP), were calcula...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/(sici)1522-2594(199902)41:2<400::aid-mrm26
更新日期:1999-02-01 00:00:00
abstract:PURPOSE:We report a series of techniques to reliably eliminate artifacts in interleaved echo-planar imaging (EPI) based diffusion-weighted imaging (DWI). METHODS:First, we integrate the previously reported multiplexed sensitivity encoding (MUSE) algorithm with a new adaptive Homodyne partial-Fourier reconstruction alg...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25318
更新日期:2015-05-01 00:00:00
abstract::In vivo 1H MRS can be used to detect and quantify the lactate resonance at 1.3 ppm provided that overlapping lipid resonances are eliminated. A homonuclear spectral editing method was developed to acquire uncontaminated 1H spectra of lactate with adiabatic pulses. An advantage of the adiabatic pulse sequence is the ab...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910300105
更新日期:1993-07-01 00:00:00
abstract::In proton magnetic resonance imaging (MRI) metallic substances lead to magnetic field distortions that often result in signal voids in the adjacent anatomic structures. Thus, metallic objects and superparamagnetic iron oxide (SPIO)-labeled cells appear as hypointense artifacts that obscure the underlying anatomy. The ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21399
更新日期:2007-11-01 00:00:00
abstract::Parallel imaging based on generalized autocalibrating partially parallel acquisitions is widely used in the clinical routine. To date, no detailed analysis has been presented describing the dependence of the image quality on the reconstruction and acquisition parameters such as the number of autocalibration signal (AC...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22803
更新日期:2011-08-01 00:00:00
abstract::MRI evaluations of intramyocardial hemorrhage in acute infarction have relied on T(2) and T(2)(*) shortening only. We propose a more comprehensive evaluation of hemorrhagic infarction based on the concept that fluctuations in T(2) and T(1) relaxation in acute reperfused infarction will reflect transient edema and hemo...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21079
更新日期:2006-12-01 00:00:00
abstract::The combination of a frequency nonselective excitation suppression method (1331 sequence) with selective excitation followed by gradient-induced dephasing of water transverse magnetization yielded suppression ratios of greater than 10,000:1. The need for gradient preemphasis and correction of B0 field shifts is discus...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910090114
更新日期:1989-01-01 00:00:00
abstract::This study investigates the potential of in vivo 31P magnetic resonance spectroscopy (MRS) to characterize musculoskeletal tumors and to determine preoperative levels of histological necrosis, which is an important clinical indicator of patient response. Pretherapy MRS was performed on 28 patients with large musculosk...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910270204
更新日期:1992-10-01 00:00:00
abstract::The fast spin-echo (FSE) sequence is frequently used as a fast data-readout technique in conjunction with other pulse sequence elements, such as in fluid-attenuated inversion-recovery (FLAIR) and double inversion-recovery (DIR) sequences. In order to implement those pulse sequences, an understanding is required of how...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.20541
更新日期:2005-07-01 00:00:00
abstract::Amide proton transfer imaging, a specific form of chemical exchange saturation transfer imaging, has previously been applied to studies of acute ischemic acidosis, stroke, and cancer. However, interpreting the resulting contrast is complicated by its dependence on the exchange rate between amides and water, the amide ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.23276
更新日期:2012-09-01 00:00:00
abstract::In in vivo phosphorus magnetic resonance spectroscopy (MRS), spectroscopic imaging (SI) can be used as a flexible localization technique, producing spectra from multiple volumes in a single examination. Presented here are phosphorus SI studies of human organs in which a selective-volume SI reconstruction was used rath...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910120302
更新日期:1989-12-01 00:00:00
abstract:PURPOSE:To propose a phase error correction scheme for monopolar time-interleaved multi-echo gradient echo water-fat imaging that allows accurate and robust complex-based quantification of the proton density fat fraction (PDFF). METHODS:A three-step phase correction scheme is proposed to address a) a phase term induce...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.26485
更新日期:2017-09-01 00:00:00
abstract::The exponential clearance rate constant, (kappa), and filtration fraction (FF) have been measured for dialysis of Gadolinium-diethylenetriaminepentaacetic acid (Gd-DTPA) (Magnevist, Berlex, Wayne, NJ) solutions by using a Look-Locker imaging technique under conditions of flow. The measured values of kappa for the Baxt...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910360412
更新日期:1996-10-01 00:00:00
abstract:PURPOSE:To quantify chemical exchange saturation transfer contrast in upper extremities of participants with lymphedema before and after standardized lymphatic mobilization therapy using correction procedures for B0 and B1 heterogeneity, and T1 relaxation. METHODS:Females with (n = 12) and without (n = 17) breast canc...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.28031
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:We propose a constrained optimization approach for designing parallel transmit (pTx) pulses satisfying all regulatory and hardware limits. We study the trade-offs between excitation accuracy, local and global specific absorption rate (SAR), and maximum and average power for small flip-angle pTx (eight channels)...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24800
更新日期:2014-04-01 00:00:00
abstract:PURPOSE:Dynamic glucose-enhanced (DGE)-MRI based on chemical exchange-sensitive MRI, that is, glucoCEST and gluco-chemical exchange-sensitive spin-lock (glucoCESL), is intrinsically prone to motion-induced artifacts because the final DGE contrast relies on the difference of images, which were acquired with a time gap o...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.28112
更新日期:2020-07-01 00:00:00
abstract::Diffusion tensor imaging (DTI) is a new imaging modality that can provide unique information on brain white matter anatomy. Measurements of water diffusion constant along multiple axes are fitted to a tensor model, from which the diffusion anisotropy and dominant fiber orientation can be estimated. Even though the ten...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.20767
更新日期:2006-02-01 00:00:00