Sensitivity of MR diffusion measurements to variations in intracellular structure: effects of nuclear size.

abstract：:Saline solutions of manganese ions (Mn2+) were used as articular contrast agents in magnetic resonance microscopy (9.4 T) of cartilage of chicken femoral condyles and pig temporomandibular joints. The diffusion of Mn2+ from the articular surface into the cartilage matrix led to a strong contrast enhancement in the car...

journal_title：Magnetic resonance in medicine

authors： Kusaka Y,Gründer W,Rumpel H,Dannhauer KH,Gersonde K

更新日期：1992-03-01 00:00:00

abstract：PURPOSE:Image-guided prostate biopsies are routinely acquired in the diagnosis and treatment monitoring of prostate cancer, yielding useful tissue for identifying metabolic biomarkers and therapeutic targets. We developed an optimized biopsy tissue culture protocol in combination with [1,6-13 C2 ]glucose labeling and q...

journal_title：Magnetic resonance in medicine

authors： Bancroft Brown J,Sriram R,VanCriekinge M,Delos Santos R,Sun J,Delos Santos J,Tabatabai ZL,Shinohara K,Nguyen H,Peehl DM,Kurhanewicz J

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:Previous studies have associated low pH in intervertebral discs (IVDs) with discogenic back pain. The purpose of this study was to determine whether quantitative CEST (qCEST) MRI can be used to detect pH changes in IVDs in vivo. METHODS:The exchange rate ksw between glycosaminoglycan (GAG) protons and water pr...

journal_title：Magnetic resonance in medicine

authors： Zhou Z,Bez M,Tawackoli W,Giaconi J,Sheyn D,de Mel S,Maya MM,Pressman BD,Gazit Z,Pelled G,Gazit D,Li D

更新日期：2016-12-01 00:00:00

abstract：:The behavior of the lithium (Li) ion in normal human erythrocytes has been studied by 7Li NMR. The uptake of Li into the cells was followed as a function of solution conditions, temperature, hematocrit, and blood age using dysprosium tripolyphosphate shift reagent. Under our conditions the uptake of Li increases with ...

journal_title：Magnetic resonance in medicine

authors： Gullapalli RP,Hawk RM,Komoroski RA

更新日期：1991-08-01 00:00:00

abstract：:In this study, a spin- and gradient-echo echo-planar imaging (SAGE EPI) MRI pulse sequence is presented that allows simultaneous measurements of gradient-echo and spin-echo dynamic susceptibility-contrast perfusion-weighted imaging data. Following signal excitation, five readout trains were acquired using spin- and gr...

journal_title：Magnetic resonance in medicine

authors： Schmiedeskamp H,Straka M,Newbould RD,Zaharchuk G,Andre JB,Olivot JM,Moseley ME,Albers GW,Bammer R

更新日期：2012-07-01 00:00:00

abstract：:Accurate and reproducible MRI R2 * relaxometry for tissue iron quantification is important in managing transfusion-dependent patients. MRI data are often acquired using array coils and reconstructed by the root-sum-square algorithm, and as such, measured signals follow the noncentral chi distribution. In this study, t...

journal_title：Magnetic resonance in medicine

authors： Feng Y,He T,Gatehouse PD,Li X,Harith Alam M,Pennell DJ,Chen W,Firmin DN

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:Define criteria for selection of optimal flip angle sets for T1 estimation and evaluate effects on T1 mapping. THEORY AND METHODS:Flip angle sets for spoiled gradient echo-based T1 mapping were selected by minimizing T1 estimate variance weighted by the joint density of M0 and T1 in an initial acquisition. The...

journal_title：Magnetic resonance in medicine

authors： Lewis CM,Hurley SA,Meyerand ME,Koay CG

更新日期：2016-09-01 00:00:00

abstract：:The experiments reported herein are the first MRI investigations of the orientational dependence of T(2) relaxation in articular cartilage at microscopic resolution over the 360 degrees angular space. For each of six canine cartilage specimens, 48 independent T(2)-weighted proton images were acquired for 12 different ...

journal_title：Magnetic resonance in medicine

authors： Xia Y,Moody JB,Alhadlaq H

更新日期：2002-09-01 00:00:00

abstract：PURPOSE:At high field, T2 -weighted (T2 w) imaging is limited by transmit field inhomogeneity and increased radiofrequency power deposition. In this work, we introduce SAMPA (Slice-selective Adiabatic Magnetization T2 PrepAration) and demonstrate its use for efficient brain T2 w imaging at 7 Tesla (T). METHODS:SAMPA w...

journal_title：Magnetic resonance in medicine

authors： Dyvorne H,Balchandani P

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:In this work, 22 configurations for remote radiofrequency (RF) coil arrays consisting of different transmit element designs for 7 Tesla (T) ultrahigh-field MRI are compared by numerical simulations. METHODS:Investigated transmit RF element types are rectangular loops, micro striplines, micro striplines with me...

journal_title：Magnetic resonance in medicine

authors： Rietsch SHG,Orzada S,Bitz AK,Gratz M,Ladd ME,Quick HH

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:Treatments using high-intensity focused ultrasound (HIFU) in the abdominal region remain challenging as a result of respiratory organ motion. A novel method is described here to achieve 3D motion-compensated ultrasound (US) MR-guided HIFU therapy using simultaneous ultrasound and MRI. METHODS:A truly hybrid US...

journal_title：Magnetic resonance in medicine

authors： Celicanin Z,Manasseh G,Petrusca L,Scheffler K,Auboiroux V,Crowe LA,Hyacinthe JN,Natsuaki Y,Santini F,Becker CD,Terraz S,Bieri O,Salomir R

更新日期：2018-05-01 00:00:00

abstract：:Diffusion-weighted imaging suffers from motion artifacts and relatively low signal quality due to the long echo times required to permit the diffusion encoding. We investigated the inclusion of a noncylindrical fourth gradient coil, dedicated entirely to diffusion encoding, into the imaging system. Standard three-axis...

journal_title：Magnetic resonance in medicine

authors： Feldman RE,Scholl TJ,Alford JK,Handler WB,Harris CT,Chronik BA

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:Develop and test an analytic correction method to correct the signal intensity variation caused by the inhomogeneous reception profile of an eight-channel phased array for hyperpolarized (13) C imaging. THEORY AND METHODS:Fiducial markers visible in anatomical images were attached to the individual coils to pr...

journal_title：Magnetic resonance in medicine

authors： Dominguez-Viqueira W,Geraghty BJ,Lau JY,Robb FJ,Chen AP,Cunningham CH

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:The feasibility of imaging musculoskeletal fibrous tissue components, such as menisci, ligaments, and tendons, with a conventional spoiled gradient echo technique is explored in vivo at 3 T and 7 T. METHODS:To this end, the echo time (TE1 ) of a conventional Fourier-encoded multicontrast three-dimensional SGPR...

journal_title：Magnetic resonance in medicine

authors： Deligianni X,Bär P,Scheffler K,Trattnig S,Bieri O

更新日期：2013-11-01 00:00:00

abstract：:Of the various techniques employed to quantify temperature changes by MR, proton resonance frequency (PRF) shift-based phase-difference imaging (PDI) is the most accurate and widely used. However, PDI is associated with various artifacts. Motivated by these limitations, we developed a new method to monitor temperature...

journal_title：Magnetic resonance in medicine

authors： Paliwal V,El-Sharkawy AM,Du X,Yang X,Atalar E

更新日期：2004-10-01 00:00:00

abstract：:Manganese-enhanced MRI has previously been used for visualization of brain architecture and functional mapping of neural pathways. The present work investigated the potential of manganese-enhanced MRI for noninvasive imaging of salivary glands in living subjects. Marked shortening of T(1) was observed in salivary glan...

journal_title：Magnetic resonance in medicine

authors： Seshadri M,Hoy A

更新日期：2010-09-01 00:00:00

abstract：:Recently, a technique based on arterial spin labeling, called dynamic arterial spin labeling (DASL (Magn Reson Med 1999;41:299-308)), has been introduced to measure simultaneously the transit time of the labeled blood from the labeling plane to the exchange site, the longitudinal relaxation time of the tissue, and the...

journal_title：Magnetic resonance in medicine

authors： Barbier EL,Silva AC,Kim SG,Koretsky AP

更新日期：2001-06-01 00:00:00

abstract：:Magnetic resonance (MR) diffusion imaging is a useful technique with which to increase our understanding of pathologic damage to the central nervous system. To fully quantitate diffusion and anisotropy in the spinal cord, as in other tissues, it is necessary to determine the diffusion tensor. If spinal cord diffusion ...

journal_title：Magnetic resonance in medicine

authors： Clark CA,Werring DJ,Miller DH

更新日期：2000-01-01 00:00:00

abstract：:Subject motion during scan is a major source of artifacts in MR examinations. Prospective motion correction is a promising technique that tracks subject motion and adjusts the imaging volume in real time; however, additional retrospective correction may be necessary to achieve robust image quality and compatibility wi...

journal_title：Magnetic resonance in medicine

authors： Banerjee S,Beatty PJ,Zhang JZ,Shankaranarayanan A

更新日期：2013-02-01 00:00:00

abstract：:The feasibility of reconstructing three-dimensional (3D) MRI data sets from limited-view projections is investigated in phantom and in vivo animal studies to improve the temporal resolution of magnetic resonance angiography without sacrificing spatial resolution. Thirty-two pairs of orthogonal biplane projections are ...

journal_title：Magnetic resonance in medicine

authors： Huang Y,Gurr D,Wright GA

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:Reference region models (RRMs) can quantify tumor perfusion in dynamic contrast-enhanced MRI without an arterial input function. Inspection of the RRM reveals that one of the free parameters in the fit is uniquely linked to the reference region and is common to all voxels. A two-step approach is proposed that t...

journal_title：Magnetic resonance in medicine

authors： Ahmed Z,Levesque IR

更新日期：2017-10-01 00:00:00

abstract：:The commercial synthetic homopolypeptide polyaspartate (average MW = 30,000, approximately 220 monomers) in solution quantitatively binds up to 40 mol Gd3+ ions per mole of polyaspartate. The water proton relaxivity of the solutions is far higher than that of clinically used or commonly investigated gadolinium(III) co...

journal_title：Magnetic resonance in medicine

authors： Cavagna F,Luchinat C,Scozzafava A,Xia Z

更新日期：1994-01-01 00:00:00

abstract：:Metabolite signals with short T(1) or T(2) are difficult to localize with full sensitivity. This limitation was overcome with the development and implementation of a single-shot, complete three-dimensional "non-echo" localization method with reduced sensitivity to spatial B(1) variation, which is suitable for measurin...

journal_title：Magnetic resonance in medicine

authors： Choi IY,Tkác I,Gruetter R

更新日期：2000-09-01 00:00:00

abstract：:In this work a model-free arterial spin labeling (ASL) quantification approach for measuring cerebral blood flow (CBF) and arterial blood volume (aBV) is proposed. The method is based on the acquisition of a train of multiple images following the labeling scheme. Perfusion is obtained using deconvolution in a manner s...

journal_title：Magnetic resonance in medicine

authors： Petersen ET,Lim T,Golay X

更新日期：2006-02-01 00:00:00

abstract：:The cytosol of intact human red blood cells was loaded with 28.1 +/- 3.4 mM of dysprosium DTPA-BMA using a hypoosmotic technique. When loaded cells were diluted with saline and control cells to give an average dysprosium concentration of 3.3 +/- 0.5 mM, the transverse relaxation rate constants R(*)(2) and R(2) increas...

journal_title：Magnetic resonance in medicine

authors： Johnson KM,Tao JZ,Kennan RP,Gore JC

更新日期：2001-05-01 00:00:00

abstract：:Dynamic contrast-enhanced MRI data in vertebral bone marrow (vBM) are currently analyzed with descriptive indices. The purpose of this study was to develop and evaluate a quantitative approach, considering the tissue composition of vBM. Therefore, a measurement of the water fraction, f(wat), and the precontrast relaxa...

journal_title：Magnetic resonance in medicine

authors： Biffar A,Sourbron S,Schmidt G,Ingrisch M,Dietrich O,Reiser MF,Baur-Melnyk A

更新日期：2010-07-01 00:00:00

abstract：:Strong, extensive magnetic fringe fields are a significant problem with magnetic resonance imaging magnets. This is particularly acute with 4-T, whole-body research magnets. To date this problem has been addressed by restricting an extensive zone around the unshielded magnet or by placing external unsaturated iron shi...

journal_title：Magnetic resonance in medicine

authors： Huson FR,Bryan RN,MacKay WW,Herrick RC,Colvin J,Ford JJ,Pissanetzky S,Plishker GA,Rocha R,Schmidt W

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:To develop a novel analytical method for quantification of chemical exchange saturation transfer (CEST) in the transient state. The proposed method aims to reduce the effects of non-chemical-exchange (non-CE) parameters on the CEST signal, emphasizing the effect of chemical exchange. METHODS:The difference in ...

journal_title：Magnetic resonance in medicine

authors： Wang Y,Zhang Y,Zhao X,Wu B,Gao JH

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:To present and validate a new method that formalizes a direct link between k-space and wavelet domains to apply separate undersampling and reconstruction for high- and low-spatial-frequency k-space data. THEORY AND METHODS:High- and low-spatial-frequency regions are defined in k-space based on the separation o...

journal_title：Magnetic resonance in medicine

authors： Sung K,Hargreaves BA

更新日期：2013-11-01 00:00:00

abstract：:Tumor pH is physiologically important since it influences a number of processes relevant to tumorigenesis and therapy. Hence, knowledge of localized pH within tumors would contribute to understanding these processes. The destructiveness, poor spatial resolution, and poor signal-to-noise ratio (SNR) of current technolo...

journal_title：Magnetic resonance in medicine

authors： van Sluis R,Bhujwalla ZM,Raghunand N,Ballesteros P,Alvarez J,Cerdán S,Galons JP,Gillies RJ

更新日期：1999-04-01 00:00:00