Real-time measurements of cellular oxygen consumption, pH, and energy metabolism using nuclear magnetic resonance spectroscopy.

abstract：:This article introduces a novel method named "Parallel Imaging and Noquist in Tandem" (PINOT) for accelerated image acquisition of cine cardiac magnetic resonance imaging. This method combines two prior information formalisms, the SPACE-RIP implementation of parallel imaging and the Noquist method for reduced-data ima...

journal_title：Magnetic resonance in medicine

authors： Hamilton LH,Fabregat JA,Moratal D,Ramamurthy S,Lerakis S,Parks WJ,Sallee D 3rd,Brummer ME

更新日期：2011-04-01 00:00:00

abstract：:The clinical application of 3D proton spectroscopic imaging (3D SI) of the human prostate requires a robust suppression of periprostatic lipid signal contamination, minimal intervoxel signal contamination, and the shortest possible measurement time. In this work, a weighted elliptical sampling of k-space, combined wit...

journal_title：Magnetic resonance in medicine

authors： Scheenen TW,Klomp DW,Röll SA,Fütterer JJ,Barentsz JO,Heerschap A

更新日期：2004-07-01 00:00:00

abstract：PURPOSE:To explore the temperature-induced signal change in two-dimensional multi-spectral imaging (2DMSI) for fast thermometry near metallic hardware to enable MR-guided focused ultrasound surgery (MRgFUS) in patients with implanted metallic hardware. METHOD:2DMSI was optimized for temperature sensitivity and applied...

journal_title：Magnetic resonance in medicine

authors： Weber H,Ghanouni P,Pascal-Tenorio A,Pauly KB,Hargreaves BA

更新日期：2018-07-01 00:00:00

abstract：:In order to determine if an increase in myocardial oxygen consumption is accompanied by changes in high energy phosphates in normal subjects and patients with dilated cardiomyopathy, phosphorus-31 spectra were acquired under resting conditions and during dobutamine infusion. In seven normal subjects, dobutamine raised...

journal_title：Magnetic resonance in medicine

authors： Schaefer S,Schwartz GG,Steinman SK,Meyerhoff DJ,Massie BM,Weiner MW

更新日期：1992-06-01 00:00:00

abstract：:Direct measurement of neural currents by means of MRI can potentially open a high temporal resolution (10-100 ms) window applicable for monitoring dynamics of neuronal activity without loss of the high spatial resolution afforded by MRI. Previously, we have shown that the alternating balanced steady state imaging affo...

journal_title：Magnetic resonance in medicine

authors： Buračas GT,Jung Y,Lee J,Buxton RB,Wong EC,Liu TT

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:To develop an MRI acquisition and reconstruction framework for volumetric cine visualization of the fetal heart and great vessels in the presence of maternal and fetal motion. METHODS:Four-dimensional (4D) depiction was achieved using a highly-accelerated multi-planar real-time balanced steady-state free prece...

journal_title：Magnetic resonance in medicine

authors： van Amerom JFP,Lloyd DFA,Deprez M,Price AN,Malik SJ,Pushparajah K,van Poppel MPM,Rutherford MA,Razavi R,Hajnal JV

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:This assesses the potential of measuring lactate in the human brain using three non-editing MRS methods at 7T and compares the accuracy and precision of the methods. METHODS:1 H MRS data were measured in the right dorsolateral prefrontal cortex using a semi-adiabatic spin-echo full-intensity acquired localized...

journal_title：Magnetic resonance in medicine

authors： Dehghani M,Do KQ,Magistretti P,Xin L

更新日期：2020-06-01 00:00:00

abstract：:The prebolus technique allows one to quantify perfusion in the human heart with a low variability by means of MRI. In this study the prebolus technique was used to determine quantitative perfusion values in the human heart under adenosine stress and to measure the myocardial perfusion reserve (MPR). Twelve healthy vol...

journal_title：Magnetic resonance in medicine

authors： Ritter C,Brackertz A,Sandstede J,Beer M,Hahn D,Köstler H

更新日期：2006-10-01 00:00:00

abstract：:Experimental procedures for obtaining localized 31P NMR spectra of humans by means of the ISIS sequence are discussed in detail. The technique is optimized for use with volume coils and with surface coils in order to measure localized 31P NMR spectra of different tissues and organs. Selective frequency-modulated (FM) ...

journal_title：Magnetic resonance in medicine

authors： Luyten PR,Groen JP,Vermeulen JW,den Hollander JA

更新日期：1989-07-01 00:00:00

abstract：:Unusually high image contrast in vivo magnetic resonance imaging of the brain becomes observable at high magnetic fields when the blood oxygenation level is lowered. The cause of the contrast has been attributed to a magnetic susceptibility effect induced by paramagnetic deoxyhemoglobin in red cells. When the cylinder...

journal_title：Magnetic resonance in medicine

authors： Ogawa S,Lee TM

更新日期：1990-10-01 00:00:00

abstract：:We exploit the intrinsic difference in magnetic resonance spin-spin relaxation time, T2, between water associated with myelin sheaths and water in other central nervous system tissue in order to measure myelin water content within any region of an image or to generate indirectly a myelin map of the brain. In normal vo...

journal_title：Magnetic resonance in medicine

authors： MacKay A,Whittall K,Adler J,Li D,Paty D,Graeb D

更新日期：1994-06-01 00:00:00

abstract：:An arterial spin labeling technique using separate RF labeling and imaging coils was used to obtain multislice perfusion images of the human brain at 3 T. Continuous RF irradiation at a peak power of 0.3 W was applied to the carotid arteries to adiabatically invert spins. Labeling was achieved without producing magnet...

journal_title：Magnetic resonance in medicine

authors： Zaharchuk G,Ledden PJ,Kwong KK,Reese TG,Rosen BR,Wald LL

更新日期：1999-06-01 00:00:00

abstract：PURPOSE:To develop a modular magnetization preparation sequence for combined T2 -preparation and multidimensional outer volume suppression (OVS) for coronary artery imaging. METHODS:A combined T2 -prepared 1D OVS sequence with fat saturation was defined to contain a 90°-60 180°60 composite nonselective tip-down pulse,...

journal_title：Magnetic resonance in medicine

authors： Zeng DY,Baron CA,Malavé MO,Kerr AB,Yang PC,Hu BS,Nishimura DG

更新日期：2020-06-01 00:00:00

abstract：:The ability to generate in vivo maps of lactate may have significant diagnostic utility in staging and treatment planning of a wide variety of cancers. The double selective multiple quantum filter technique (SelMQC) has been shown to be effective for nonlocalized detection of lactate with little or no interference fro...

journal_title：Magnetic resonance in medicine

authors： Pickup S,Lee SC,Mancuso A,Glickson JD

更新日期：2008-08-01 00:00:00

abstract：:The concentration of oxygen within cells is important in many physiological and pathological processes, but such oxygen-dependent phenomena are generally studied as a function of the concentration of extracellular oxygen, due to a lack of suitable methods. Electron parmamagnetic resonance (EPR) oximetric techniques of...

journal_title：Magnetic resonance in medicine

authors： Glockner JF,Norby SW,Swartz HM

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:To present and validate a new method that formalizes a direct link between k-space and wavelet domains to apply separate undersampling and reconstruction for high- and low-spatial-frequency k-space data. THEORY AND METHODS:High- and low-spatial-frequency regions are defined in k-space based on the separation o...

journal_title：Magnetic resonance in medicine

authors： Sung K,Hargreaves BA

更新日期：2013-11-01 00:00:00

abstract：:Magnetization transfer experiments using an off-resonance irradiation technique were performed on bovine serum albumin solutions by varying the irradiation frequency and the concentration. A transition of the magnetization transfer spectrum from Lorentzian to Gaussian line shape was observed around the critical concen...

journal_title：Magnetic resonance in medicine

authors： Iino M

更新日期：1994-10-01 00:00:00

abstract：:A 3-T study is presented, comparing the ability of two (1) H spectroscopy pulse sequences, Carr-Purcell point resolved spectroscopy (CPRESS; TE = 45 msec), and conventional PRESS (TE = 35 msec), to separate between groups of 20 normal control (NC) and 20 mild cognitive impairment (MCI) subjects. Both sequences showed ...

journal_title：Magnetic resonance in medicine

authors： Hancu I,Gillen R,Cowan J,Zimmerman EA

更新日期：2011-06-01 00:00:00

abstract：:A novel iterative k-space data-driven technique, namely parallel reconstruction using null operations (PRUNO), is presented for parallel imaging reconstruction. In PRUNO, both data calibration and image reconstruction are formulated into linear algebra problems based on a generalized system model. An optimal data cali...

journal_title：Magnetic resonance in medicine

authors： Zhang J,Liu C,Moseley ME

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:To develop a novel analytical method for quantification of chemical exchange saturation transfer (CEST) in the transient state. The proposed method aims to reduce the effects of non-chemical-exchange (non-CE) parameters on the CEST signal, emphasizing the effect of chemical exchange. METHODS:The difference in ...

journal_title：Magnetic resonance in medicine

authors： Wang Y,Zhang Y,Zhao X,Wu B,Gao JH

更新日期：2017-11-01 00:00:00

abstract：:Human brain white matter exhibits an uncommonly strong dispersion of 1/T1 at high fields. An additional relaxation pathway via the myelin lipids, which are not directly visible to medical NMR due to their fast T2 decay, is proposed. Relaxation dispersion data are successfully analyzed on the basis of this model. ...

journal_title：Magnetic resonance in medicine

authors： Fischer HW,Van Haverbeke Y,Schmitz-Feuerhake I,Muller RN

更新日期：1989-03-01 00:00:00

abstract：PURPOSE:The purpose of this study is to increase the robustness of MR fingerprinting (MRF) toward subject motion. METHODS:A novel reconstruction algorithm, MOtion insensitive MRF (MORF), was developed, which uses an iterative reconstruction based retrospective motion correction approach. Each iteration loops through t...

journal_title：Magnetic resonance in medicine

authors： Mehta BB,Ma D,Pierre EY,Jiang Y,Coppo S,Griswold MA

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:The purpose of this study was to investigate the feasibility of in vivo imaging of human pancreatic ductal cells by OATP1B3 reporter gene under MRI. METHODS:A human cell line (PANC-1) derived from the pancreatic ductal epithelium was used in this study. After transduction of OATP1B3, the cellular physiological...

journal_title：Magnetic resonance in medicine

authors： Wu MR,Hsiao JK,Liu HM,Huang YY,Tseng YJ,Chou PT,Weng TI,Yang CY

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:At high field, T2 -weighted (T2 w) imaging is limited by transmit field inhomogeneity and increased radiofrequency power deposition. In this work, we introduce SAMPA (Slice-selective Adiabatic Magnetization T2 PrepAration) and demonstrate its use for efficient brain T2 w imaging at 7 Tesla (T). METHODS:SAMPA w...

journal_title：Magnetic resonance in medicine

authors： Dyvorne H,Balchandani P

更新日期：2016-12-01 00:00:00

abstract：:Intermolecular double quantum coherences (iDQCs), signals that result from simultaneous transitions of two or more separated spins, are known to produce images that are highly sensitive to subvoxel structure, particularly local anisotropy. Here we demonstrate how iDQCs signal can be used to efficiently detect the anis...

journal_title：Magnetic resonance in medicine

authors： Branca RT,Chen YM,Mouraviev V,Galiana G,Jenista ER,Kumar C,Leuschner C,Warren WS

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:Magnetic resonance imaging of humans at high magnetic field strengths is strongly influenced by the interference of the radiofrequency (RF) electromagnetic field and the body. To minimize this effect, multiple RF sources could be used. A novel setup (called multimode, coaxial waveguide) is proposed that facilit...

journal_title：Magnetic resonance in medicine

authors： Andreychenko A,Kroeze H,Boer VO,Lagendijk JJ,Luijten PR,van den Berg CA

更新日期：2014-04-01 00:00:00

abstract：:Fast proton magnetic resonance spectroscopic imaging (MRSI) using a multi-element head-coil array is examined with respect to three aspects: the coil design, the use of an appropriate signal combination method, and the design of the MRSI pulse sequence itself. An eight-element head-coil array has been developed to inc...

journal_title：Magnetic resonance in medicine

authors： Schäffter T,Börnert P,Leussler C,Carlsen IC,Leibfritz D

更新日期：1998-08-01 00:00:00

abstract：:Stejskal and Tanner's ingenious pulsed field gradient design from 1965 has made diffusion NMR and MRI the mainstay of most studies seeking to resolve microstructural information in porous systems in general and biological systems in particular. Methods extending beyond Stejskal and Tanner's design, such as double diff...

journal_title：Magnetic resonance in medicine

authors： Shemesh N,Jespersen SN,Alexander DC,Cohen Y,Drobnjak I,Dyrby TB,Finsterbusch J,Koch MA,Kuder T,Laun F,Lawrenz M,Lundell H,Mitra PP,Nilsson M,Özarslan E,Topgaard D,Westin CF

更新日期：2016-01-01 00:00:00

abstract：:Recent in vivo 1H MRS studies of muscle oxygen levels by means of myoglobin (Mb) oxygenation have necessitated an investigation of the possible contamination from deoxy-hemoglobin (Hb). To determine the contribution of Hb in these NMR measurements, we studied the NMR visibility of histidyl N-delta proton of Hb in lyse...

journal_title：Magnetic resonance in medicine

authors： Wang DJ,Nioka S,Wang Z,Leigh JS,Chance B

更新日期：1993-12-01 00:00:00

abstract：PURPOSE:This study aimed to evaluate the reproducibility and specificity of quantitative magnetization transfer (qMT) imaging for monitoring spinal cord injuries (SCIs). METHODS:MRI scans were performed in anesthetized monkeys at 9.4T, before and serially after a unilateral lesion of the cervical spinal cord. A two-po...

journal_title：Magnetic resonance in medicine

authors： Wang F,Li K,Mishra A,Gochberg D,Min Chen L,Gore JC

更新日期：2016-04-01 00:00:00