A highly sensitive lactate editing technique for surface coil spectroscopic imaging in vivo.

Abstract:

:A lactate editing sequence based on the use of spin-locking pulses with surface coils is described. The sequence retains more than 90% of the available lactate magnetization and suppresses at least 95% of the lipid signal in a single scan and ca. 99.5% after a simple two step cycle. The technique allows simultaneous observation of lactate and uncoupled metabolites in the range 2 to 3 ppm. The sequence was combined with two-dimensional spectroscopic imaging to obtain a lactate map of an ischemic rat brain in vivo.

journal_name

Magn Reson Med

authors

Bourgeois D,Kozlowski P

doi

10.1002/mrm.1910290320

subject

Has Abstract

pub_date

1993-03-01 00:00:00

pages

402-6

issue

3

eissn

0740-3194

issn

1522-2594

journal_volume

29

pub_type

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