Novel pH-sensitive paramagnetic liposomes with improved MR properties.

abstract：:Quantitative estimation of T1 is a challenging but important task inherent to many clinical applications. The most commonly used paradigm for estimating T1 in vivo involves performing a sequence of spoiled gradient-recalled echo acquisitions at different flip angles, followed by fitting of an exponential model to the ...

journal_title：Magnetic resonance in medicine

authors： Trzasko JD,Mostardi PM,Riederer SJ,Manduca A

更新日期：2013-06-01 00:00:00

abstract：:Cirrhosis is an important and growing public health problem, affecting millions of Americans and many more people internationally. A pathological hallmark of the progression to cirrhosis is the development of liver fibrosis, so that monitoring the appearance and progression of liver fibrosis can be used to guide thera...

journal_title：Magnetic resonance in medicine

authors： Chung S,Breton E,Mannelli L,Axel L

更新日期：2011-04-01 00:00:00

abstract：:Partial-volume effects (PVE) in stroke imaging could hinder proper delineation of normal, ischemic, and at-risk tissues. Cerebral-blood-flow (CBF) and apparent diffusion coefficient (ADC) were measured at high and low resolution (HR = 128 x 128, LR = 64 x 64) in focal ischemia in rats during the acute phase. The data ...

journal_title：Magnetic resonance in medicine

authors： Ren H,Shen Q,Bardutzky J,Fisher M,Duong TQ

更新日期：2004-12-01 00:00:00

abstract：PURPOSE:Within multiple sclerosis (MS) lesions iron is present in chronically activated microglia. Thus, iron detection with MRI might provide a biomarker for chronic inflammation within lesions. Here, we examine contributions of iron and myelin to magnetic susceptibility of lesions on quantitative susceptibility mappi...

journal_title：Magnetic resonance in medicine

authors： Wisnieff C,Ramanan S,Olesik J,Gauthier S,Wang Y,Pitt D

更新日期：2015-08-01 00:00:00

abstract：:In active catheter tracking, small RF coils are attached to the catheter for localization. For interactive catheter steering at vessel branchings, it is necessary to visualize not only a single point near the catheter tip but also the entire shape and orientation of the catheter's distal end. Therefore, a 35-mm-long t...

journal_title：Magnetic resonance in medicine

authors： Zuehlsdorff S,Umathum R,Volz S,Hallscheidt P,Fink C,Semmler W,Bock M

更新日期：2004-07-01 00:00:00

abstract：:To investigate the dependency of T(1) relaxation on mechanical strain in articular cartilage, quantitative magnetic resonance T(1) imaging experiments were carried out on cartilage before/after the tissue was immersed in gadolinium contrast agent and when the tissue was being compressed (up to ∼ 48% strains). The spat...

journal_title：Magnetic resonance in medicine

authors： Xia Y,Wang N,Lee J,Badar F

更新日期：2011-06-01 00:00:00

abstract：:A new contrast preparation based on modified driven equilibrium Fourier transfer is introduced and evaluated for generation of T1-weighted images for assessment of the myocardial perfusion with contrast agent first-pass kinetics. The new preparation scheme produces T1 contrast with insensitivity to arrhythmias in pros...

journal_title：Magnetic resonance in medicine

authors： Tsekos NV,Zhang Y,Merkle H,Wilke N,Jerosch-Herold M,Stillman A,Uğurbil K

更新日期：1995-10-01 00:00:00

abstract：PURPOSE:To compare the performance of an 8-channel surface coil/clamshell transmitter and 32-channel head array coil/birdcage transmitter for hyperpolarized 13 C brain metabolic imaging. METHODS:To determine the field homogeneity of the radiofrequency transmitters, B1 + mapping was performed on an ethylene glycol head...

journal_title：Magnetic resonance in medicine

authors： Autry AW,Gordon JW,Carvajal L,Mareyam A,Chen HY,Park I,Mammoli D,Vareth M,Chang SM,Wald LL,Xu D,Vigneron DB,Nelson SJ,Li Y

更新日期：2019-08-01 00:00:00

abstract：:A previously developed eigenvector formalism is adapted to off-resonance in the transient response of quasiperiodic steady-state free precession (SSFP) sequences, including TrueFISP as a special case. The effective relaxation rates for essentially parallel and perpendicular deviations from the steady state are determi...

journal_title：Magnetic resonance in medicine

authors： Ganter C

更新日期：2004-08-01 00:00:00

abstract：:The potential of quantitative parameter images of the relaxation times T1 and T2, the proton density rho and the apparent diffusion coefficient (ADC) to characterize three different experimental rat brain tumors (F98 glioma, RN6 Schwannoma, and E376 neuroblastoma) was studied. All parameter values, as determined in hi...

journal_title：Magnetic resonance in medicine

authors： Eis M,Els T,Hoehn-Berlage M

更新日期：1995-12-01 00:00:00

abstract：:Hydrogen, sodium, and fluorine (added F-) NMR spectra of venous and oxygenated blood were measured. The fluorine resonance was seen as a single peak in both samples, and all three resonances exhibited the same deoxy-oxy shift. Because F- exchanges slowly across the red cell membrane, and because sodium is 95% extracel...

journal_title：Magnetic resonance in medicine

authors： Brooks RA,Brunetti A,Alger JR,Di Chiro G

更新日期：1989-11-01 00:00:00

abstract：:In order to obtain proton magnetic resonance spectra from the normal human kidney in vivo, we employed a STEAM sequence with delay times TE = 10 ms and TM = 30 ms. Signals are attenuated during STEAM sequences by J-coupling effects and by macroscopic movement of the sample. The combination of short echo times and resp...

journal_title：Magnetic resonance in medicine

authors： Dixon RM,Frahm J

更新日期：1994-05-01 00:00:00

abstract：:With diffusion tensor imaging, the diffusion of water molecules through brain structures is quantified by parameters, which are estimated assuming monoexponential diffusion-weighted signal attenuation. The estimated diffusion parameters, however, depend on the diffusion weighting strength, the b-value, which hampers t...

journal_title：Magnetic resonance in medicine

authors： Veraart J,Poot DH,Van Hecke W,Blockx I,Van der Linden A,Verhoye M,Sijbers J

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:To test and implement a motion-robust and respiratory-resolved 3D Radial Flow framework that addresses the need for rapid, high resolution imaging in neonatal patients with congenital heart disease. METHODS:A 4-point velocity encoding and 3D radial trajectory with double-golden angle ordering was combined with...

journal_title：Magnetic resonance in medicine

authors： Schrauben EM,Lim JM,Goolaub DS,Marini D,Seed M,Macgowan CK

更新日期：2020-02-01 00:00:00

abstract：:To quantify the extraction fraction, E, for gadopentetate across tumor capillaries, R3230 adenocarcinomas were implanted in the mammary fat pads of seven rats. The value of E was determined by using a two-compartment tissue model in which the endothelial transfer coefficient, K(PS) (ml x min(-1) x cc(-1) of tissue), w...

journal_title：Magnetic resonance in medicine

authors： Daldrup HE,Shames DM,Husseini W,Wendland MF,Okuhata Y,Brasch RC

更新日期：1998-10-01 00:00:00

abstract：PURPOSE:To assess the risk of radiofrequency (RF)-induced heating in patients with MR-conditional pacemaker (PM) systems, in the presence of another lead abandoned from a previous implant. METHODS:Four commercial pacemaker leads were placed beside a MR-conditional PM system, inside a human trunk simulator. The phantom...

journal_title：Magnetic resonance in medicine

authors： Mattei E,Gentili G,Censi F,Triventi M,Calcagnini G

更新日期：2015-01-01 00:00:00

abstract：:The multiexponential behavior of the decay curves obtained in vitro by a Carr-Purcell-Meiboom-Gill (CPMG) sequence from spleens and kidneys of mice is analyzed. The mice were inoculated with the acute lymphocytic P388 leukemic cells and treated with the anticancer drug cis-diamminedichloroplatinum(II), cis-Pt. Kidneys...

journal_title：Magnetic resonance in medicine

authors： François A,Van Gerven L,Atassi G,Eisendrath H,Gielen M,Willem R

更新日期：1988-08-01 00:00:00

abstract：PURPOSE:To demonstrate the feasibility of imaging a bolus of co-polarized [1-13 C]pyruvate and 13 C-urea to simultaneously assess both metabolism and perfusion in the rodent heart. METHODS:Copolarized [1-13 C]pyruvate and 13 C-urea was imaged using a multi-echo, flow-sensitized spiral pulse sequence. Healthy rats were...

journal_title：Magnetic resonance in medicine

authors： Lau AZ,Miller JJ,Robson MD,Tyler DJ

更新日期：2017-01-01 00:00:00

abstract：:Human mesenchymal stem cells (hMSCs) were labeled with Ferucarbotran by simple incubation and cultured for up to 14 d. Iron content was determined by spectrometry and the intracellular localization of the contrast agent uptake was studied by electron and confocal microscopy. At various time points after labeling, rang...

journal_title：Magnetic resonance in medicine

authors： Henning TD,Wendland MF,Golovko D,Sutton EJ,Sennino B,Malek F,Bauer JS,McDonald DM,Daldrup-Link H

更新日期：2009-08-01 00:00:00

abstract：PURPOSE:The aim of this work was to quantify the extent of lipid-rich necrotic core (LRNC) and intraplaque hemorrhage (IPH) in atherosclerotic plaques. METHODS:Patients scheduled for carotid endarterectomy underwent four-point Dixon and T1-weighted magnetic resonance imaging (MRI) at 3 Tesla. Fat and R2* maps were gen...

journal_title：Magnetic resonance in medicine

authors： Koppal S,Warntjes M,Swann J,Dyverfeldt P,Kihlberg J,Moreno R,Magee D,Roberts N,Zachrisson H,Forssell C,Länne T,Treanor D,de Muinck ED

更新日期：2017-07-01 00:00:00

abstract：:Chemically-fixed nervous tissues are well-suited for high-resolution, time-intensive MRI acquisitions without motion artifacts, such as those required for brain atlas projects, but the aldehyde fixatives used may significantly alter tissue MRI properties. To test this hypothesis, this study characterized the impact of...

journal_title：Magnetic resonance in medicine

authors： Shepherd TM,Thelwall PE,Stanisz GJ,Blackband SJ

更新日期：2009-07-01 00:00:00

abstract：:The myelin sheath, which is wrapped around the axons in the brain, can be affected by many diseases, resulting in cognitive and physical disability. Other work showed water in the myelin sheath has a T2 approximately 15 ms. The current standard technique to estimate the fraction of myelin water in vivo is to collect m...

journal_title：Magnetic resonance in medicine

authors： Jones CK,Xiang QS,Whittall KP,MacKay AL

更新日期：2004-03-01 00:00:00

abstract：:Magnetization transfer imaging (MT) and localized proton spectroscopy (1H-MRS) were utilized in the evaluation of lesions (high signal abnormalities on T2-weighted images) and normal-appearing white matter (NAWM) in multiple sclerosis (MS). Eleven patients with a clinical diagnosis of MS were independently evaluated w...

journal_title：Magnetic resonance in medicine

authors： Hiehle JF Jr,Lenkinski RE,Grossman RI,Dousset V,Ramer KN,Schnall MD,Cohen JA,Gonzalez-Scarano F

更新日期：1994-09-01 00:00:00

abstract：:The estrogen receptor (ER) is a major prognostic biomarker of breast cancer, currently determined in surgical specimens by immunohistochemistry. Two new ER-targeted probes, pyridine-tetra-acetate-Gd chelate (PTA-Gd) conjugated either to 17β-estradiol (EPTA-Gd) or to tamoxifen (TPTA-Gd), were explored as contrast agent...

journal_title：Magnetic resonance in medicine

authors： Pais A,Biton IE,Margalit R,Degani H

更新日期：2013-07-01 00:00:00

abstract：:The preovulatory rat follicle reaches a diameter of 1 mm with no internal blood vessels. Nutrient supply to the enclosed oocyte depends solely on passive diffusion across the follicular wall and the follicular fluid. Spin-echo and stimulated-echo NMR microscopy experiments were applied here for studying modulations in...

journal_title：Magnetic resonance in medicine

authors： Tempel C,Schiffenbauer YS,Meir G,Neeman M

更新日期：1995-08-01 00:00:00

abstract：:Advances in modern magnetic resonance imaging (MRI) pulse sequences have enabled clinically practical cortical bone imaging. Human cortical bone is known to contain a distribution of T(1) and T(2) components attributed to bound and pore water, although clinical imaging approaches have yet to discriminate bound from po...

journal_title：Magnetic resonance in medicine

authors： Horch RA,Gochberg DF,Nyman JS,Does MD

更新日期：2012-12-01 00:00:00

abstract：:In the dynamic nuclear polarization process, microwave irradiation facilitates exchange of polarization from a radical's unpaired electron to nuclear spins at cryogenic temperatures, increasing polarization by >10,000. Doping samples with Gd(3+) ions further increases the achievable solid-state polarization. However, ...

journal_title：Magnetic resonance in medicine

authors： Gordon JW,Fain SB,Rowland IJ

更新日期：2012-12-01 00:00:00

abstract：:The analysis of abdominal and thoracic dynamic contrast-enhanced MRI is often impaired by artifacts and misregistration caused by physiological motion. Breath-hold is too short to cover long acquisitions. A novel multipurpose reconstruction technique, entitled dynamic contrast-enhanced generalized reconstruction by in...

journal_title：Magnetic resonance in medicine

authors： Filipovic M,Vuissoz PA,Codreanu A,Claudon M,Felblinger J

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:To integrate markerless head motion tracking with prospectively corrected neuroanatomical MRI sequences and to investigate high-frequency motion correction during imaging echo trains. METHODS:A commercial 3D surface tracking system, which estimates head motion by registering point cloud reconstructions of the ...

journal_title：Magnetic resonance in medicine

authors： Frost R,Wighton P,Karahanoğlu FI,Robertson RL,Grant PE,Fischl B,Tisdall MD,van der Kouwe A

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:Oscillating gradient (OG) enables the access of short diffusion times for time-dependent diffusion MRI (dMRI); however, it poses several technical challenges for clinical use. This study proposes a 3D oscillating gradient-prepared gradient spin-echo (OGprep-GRASE) sequence to improve SNR and shorten acquisition...

journal_title：Magnetic resonance in medicine

authors： Wu D,Liu D,Hsu YC,Li H,Sun Y,Qin Q,Zhang Y

更新日期：2021-01-01 00:00:00