Abstract:
:AFI (actual flip angle imaging) represents an interesting approach to map the B(1) transmit fields by measuring the spatial variations of the effective flip angle. However, the accuracy of the technique relies on the adequate spoiling of transverse magnetization. In the present work configuration theory was employed to develop a proper RF and gradient spoiling scheme for the AFI technique, making the sequence robust against off-resonance without the need of large spoiling gradients. Furthermore, numerical simulations were performed to predict the steady-state signals and, hence, the accuracy of the AFI technique as a function of the sequence and tissue parameters. It is shown that the spoiling properties of the sequence are mainly defined by the phase shift increment phi of the RF pulses and the diffusion sensitivity resulting from the unbalanced gradients of the sequence. Adequate spoiling may be achieved for a reasonable range of tissue parameters and flip angles for moderate spoiling gradients if a favorable value for phi is chosen. Phantom and in vivo head imaging experiments show an excellent agreement with the theoretical predictions, indicating that the proper operating range of the approach may be reliably predicted by the theory.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Nehrke Kdoi
10.1002/mrm.21592subject
Has Abstractpub_date
2009-01-01 00:00:00pages
84-92issue
1eissn
0740-3194issn
1522-2594journal_volume
61pub_type
杂志文章abstract:PURPOSE:To investigate a computationally efficient method for optimizing the Cramér-Rao Lower Bound (CRLB) of quantitative sequences without using approximations or an analytical expression of the signal. METHODS:Automatic differentiation was applied to Bloch simulations and used to optimize several quantitative seque...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27832
更新日期:2019-10-01 00:00:00
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journal_title:Magnetic resonance in medicine
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journal_title:Magnetic resonance in medicine
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journal_title:Magnetic resonance in medicine
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更新日期:2007-11-01 00:00:00
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journal_title:Magnetic resonance in medicine
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journal_title:Magnetic resonance in medicine
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journal_title:Magnetic resonance in medicine
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更新日期:1998-01-01 00:00:00
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journal_title:Magnetic resonance in medicine
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更新日期:2018-07-01 00:00:00
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更新日期:2016-05-01 00:00:00
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更新日期:2020-06-01 00:00:00
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journal_title:Magnetic resonance in medicine
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更新日期:2015-05-01 00:00:00
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journal_title:Magnetic resonance in medicine
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更新日期:1994-02-01 00:00:00
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journal_title:Magnetic resonance in medicine
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journal_title:Magnetic resonance in medicine
pub_type: 临床试验,杂志文章
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更新日期:2019-03-01 00:00:00
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更新日期:2015-02-01 00:00:00
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journal_title:Magnetic resonance in medicine
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更新日期:1993-03-01 00:00:00
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