Quantitative transport mapping (QTM) of the kidney with an approximate microvascular network.

Abstract:

PURPOSE:Proof-of-concept study of mapping renal blood flow vector field according to the inverse solution to a mass transport model of time resolved tracer-labeled MRI data. THEORY AND METHODS:To determine tissue perfusion according to the underlying physics of spatiotemporal tracer concentration variation, the mass transport equation is integrated over a voxel with an approximate microvascular network for fitting time-resolved tracer imaging data. The inverse solution to the voxelized transport equation provides the blood flow vector field, which is referred to as quantitative transport mapping (QTM). A numerical microvascular network modeling the kidney with computational fluid dynamics reference was used to verify the accuracy of QTM and the current Kety's method that uses a global arterial input function. Multiple post-label delay arterial spin labeling (ASL) of the kidney on seven subjects was used to assess QTM in vivo feasibility. RESULTS:Against the ground truth in the numerical model, the error in flow estimated by QTM (18.6%) was smaller than that in Kety's method (45.7%, 2.5-fold reduction). The in vivo kidney perfusion quantification by QTM (cortex: 443 ± 58 mL/100 g/min and medulla: 190 ± 90 mL/100 g/min) was in the range of that by Kety's method (482 ± 51 mL/100 g/min in the cortex and 242 ± 73 mL/100 g/min in the medulla), and QTM provided better flow homogeneity in the cortex region. CONCLUSIONS:QTM flow velocity mapping is feasible from multi-delay ASL MRI data based on inverting the transport equation. In a numerical simulation, QTM with deconvolution in space and time provided more accurate perfusion quantification than Kety's method with deconvolution in time only.

journal_name

Magn Reson Med

authors

Zhou L,Zhang Q,Spincemaille P,Nguyen TD,Morgan J,Dai W,Li Y,Gupta A,Prince MR,Wang Y

doi

10.1002/mrm.28584

subject

Has Abstract

pub_date

2021-04-01 00:00:00

pages

2247-2262

issue

4

eissn

0740-3194

issn

1522-2594

journal_volume

85

pub_type

杂志文章
  • Measurement of fibrin concentration by fast field-cycling NMR.

    abstract::The relaxation of (1)H nuclei due to their interaction with quadrupolar (14)N nuclei in gel structures is measured using fast field-cycling NMR. This phenomenon called quadrupolar dips has been reported in different (1)H-(14)N bond-rich species. In this study, we have studied quadrupolar dips in fibrin, an insoluble p...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.23117

    authors: Broche LM,Ismail SR,Booth NA,Lurie DJ

    更新日期:2012-05-01 00:00:00

  • Noninvasive in vivo oximetric imaging by radiofrequency FT EPR.

    abstract::A novel method, called relaxo-oximetry, for rapid spatially resolved in vivo measurements of oxygen concentration using time-domain radiofrequency (RF) electron paramagnetic resonance (EPR) is described. Time-domain data from triaryl methyl (TAM)-based single-electron contrast agents were processed by systematic delet...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10133

    authors: Subramanian S,Yamada K,Irie A,Murugesan R,Cook JA,Devasahayam N,Van Dam GM,Mitchell JB,Krishna MC

    更新日期:2002-05-01 00:00:00

  • Per-subject characterization of bolus width in pulsed arterial spin labeling using bolus turbo sampling.

    abstract::Quantification of cerebral blood flow using QUIPSSII pulsed arterial spin labeling requires that the QUIPSS saturation delay TI1 is shorter than the natural temporal bolus width. Yet the duration of the bolus of tagged spins entering the region of interest varies during vasoactive stimuli such as gaseous challenges or...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24412

    authors: Villien M,Chipon E,Troprès I,Bouvier J,Cantin S,Chechin D,Le Bas JF,Krainik A,Warnking JM

    更新日期:2013-06-01 00:00:00

  • Parallel transmit capability of various RF transmit elements and arrays at 7T MRI.

    abstract:PURPOSE:In this work, 22 configurations for remote radiofrequency (RF) coil arrays consisting of different transmit element designs for 7 Tesla (T) ultrahigh-field MRI are compared by numerical simulations. METHODS:Investigated transmit RF element types are rectangular loops, micro striplines, micro striplines with me...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26704

    authors: Rietsch SHG,Orzada S,Bitz AK,Gratz M,Ladd ME,Quick HH

    更新日期:2018-02-01 00:00:00

  • Localized 1H NMR measurements of 2-pyrrolidinone in human brain in vivo.

    abstract::Localized 1H NMR homonuclear J editing spectroscopy was used to measure the concentration of 2-pyrrolidinone (PRDN) in the human occipital lobe of five normal and six epileptic subjects taking vigabatrin. PRDN is a lactam cyclization product of gamma-aminobutyric acid (GABA). From a localized volume of 13.5 cm3 in the...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1522-2594(199905)41:5<889::aid-mrm6>

    authors: Hyder F,Petroff OA,Mattson RH,Rothman DL

    更新日期:1999-05-01 00:00:00

  • In vivo and ex vivo MR imaging of slowly cycling melanoma cells.

    abstract::Slowly cycling cells are believed to play a critical role in tumor progression and metastatic dissemination. The goal of this study was to develop a method for in vivo detection of slowly cycling cells. To distinguish these cells from more rapidly proliferating cells that constitute the vast majority of cells in tumor...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22917

    authors: Magnitsky S,Roesch A,Herlyn M,Glickson JD

    更新日期:2011-11-01 00:00:00

  • In vivo 13C magnetic resonance spectroscopy of human brain on a clinical 3 T scanner using [2-13C]glucose infusion and low-power stochastic decoupling.

    abstract::This study presents the detection of [2-(13)C]glucose metabolism in the carboxylic/amide region in the human brain, and demonstrates that the cerebral metabolism of [2-(13)C]glucose can be studied in human subjects in the presence of severe hardware constraints of widely available 3 T clinical scanners and with low-po...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22044

    authors: Li S,Zhang Y,Wang S,Yang J,Ferraris Araneta M,Farris A,Johnson C,Fox S,Innis R,Shen J

    更新日期:2009-09-01 00:00:00

  • Partial Fourier techniques in single-shot cross-term spatiotemporal encoded MRI.

    abstract:PURPOSE:Cross-term spatiotemporal encoding (xSPEN) is a single-shot approach with exceptional immunity to field heterogeneities, the images of which faithfully deliver 2D spatial distributions without requiring a priori information or using postacquisition corrections. xSPEN, however, suffers from signal-to-noise ratio...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26824

    authors: Zhang Z,Frydman L

    更新日期:2018-03-01 00:00:00

  • New "multicolor" polypeptide diamagnetic chemical exchange saturation transfer (DIACEST) contrast agents for MRI.

    abstract::An array of 33 prototype polypeptides was examined as putative contrast agents that can be distinguished from each other based on the chemical exchange saturation transfer (CEST) mechanism. These peptides were chosen based on predictions of the chemical exchange rates of exchangeable amide, amine, and hydroxyl protons...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21683

    authors: McMahon MT,Gilad AA,DeLiso MA,Berman SM,Bulte JW,van Zijl PC

    更新日期:2008-10-01 00:00:00

  • Correction of motion-induced susceptibility artifacts and B0 drift during proton resonance frequency shift-based MR thermometry in the pelvis with background field removal methods.

    abstract:PURPOSE:The linear change of the water proton resonance frequency shift (PRFS) with temperature is used to monitor temperature change based on the temporal difference of image phase. Here, the effect of motion-induced susceptibility artifacts on the phase difference was studied in the context of mild radio frequency hy...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.28302

    authors: Wu M,Mulder HT,Baron P,Coello E,Menzel MI,van Rhoon GC,Haase A

    更新日期:2020-11-01 00:00:00

  • Aortic wall shear stress in Marfan syndrome.

    abstract::The aim of this study was to quantify changes in thoracic aortic wall shear stress (WSS) in asymptomatic patients with Marfan syndrome (MFS) compared with healthy controls. WSS in the thoracic aorta was quantified based on time-resolved 3D phase contrast MRI with three-directional velocity encoding (4D flow MRI, tempo...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24562

    authors: Geiger J,Arnold R,Herzer L,Hirtler D,Stankovic Z,Russe M,Langer M,Markl M

    更新日期:2013-10-01 00:00:00

  • Use of a projection reconstruction method to decrease motion sensitivity in diffusion-weighted MRI.

    abstract::Diffusion-weighted MRI is a clinically useful technique, but its utility is compromised by high sensitivity to patient motion. Use of radial-scan data acquisition and projection reconstruction, rather than the conventional Fourier imaging method, can substantially reduce the sensitivity to global translational motion ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910290619

    authors: Gmitro AF,Alexander AL

    更新日期:1993-06-01 00:00:00

  • Motion compensated generalized reconstruction for free-breathing dynamic contrast-enhanced MRI.

    abstract::The analysis of abdominal and thoracic dynamic contrast-enhanced MRI is often impaired by artifacts and misregistration caused by physiological motion. Breath-hold is too short to cover long acquisitions. A novel multipurpose reconstruction technique, entitled dynamic contrast-enhanced generalized reconstruction by in...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22644

    authors: Filipovic M,Vuissoz PA,Codreanu A,Claudon M,Felblinger J

    更新日期:2011-03-01 00:00:00

  • On the application of ultra-fast RARE experiments.

    abstract::The ultra-fast application of the RARE experiment is described in detail, with special emphasis on its multifarious applications with preparation experiments that produce transverse magnetization. The factors affecting the temporal evolution of the magnetization during the experiment are described, and the implication...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910270114

    authors: Norris DG,Börnert P,Reese T,Leibfritz D

    更新日期:1992-09-01 00:00:00

  • Fe(III) distribution varies substantially within and between atherosclerotic plaques.

    abstract:PURPOSE:Vulnerable atherosclerotic plaques are structurally weak and prone to rupture, presumably due to local oxidative stress. Redox active iron is linked to oxidative stress and the aim of this study was to investigate the distribution of Fe(III) in carotid plaques and its relation to vulnerability for rupture. MET...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24687

    authors: Gustafsson H,Hallbeck M,Norell M,Lindgren M,Engström M,Rosén A,Zachrisson H

    更新日期:2014-02-01 00:00:00

  • High resolution hyperpolarized 13 C MRSI using SPICE at 9.4T.

    abstract:PURPOSE:To test the feasibility of using the SPICE (SPectroscopic Imaging by exploiting spatiospectral CorrElation) technique, which uses the partial separability of spectroscopic data, for high resolution hyperpolarized (HP) 13 C spectroscopic imaging. METHODS:Numerical simulations were performed to investigate the i...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27061

    authors: Lee H,Song JE,Shin J,Joe E,Joo CG,Choi YS,Song HT,Kim DH

    更新日期:2018-08-01 00:00:00

  • Highly accelerated submillimeter resolution 3D GRASE with controlled T 2 blurring in T 2 -weighted functional MRI at 7 Tesla: A feasibility study.

    abstract:PURPOSE:To achieve highly accelerated submillimeter resolution T 2 -weighted functional MRI at 7T by developing a three-dimensional gradient and spin echo imaging (GRASE) with inner-volume sel...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.28589

    authors: Park S,Torrisi S,Townsend JD,Beckett A,Feinberg DA

    更新日期:2020-11-24 00:00:00

  • Field camera measurements of gradient and shim impulse responses using frequency sweeps.

    abstract:PURPOSE:Applications of dynamic shimming require high field fidelity, and characterizing the shim field dynamics is therefore necessary. Modeling the system as linear and time-invariant, the purpose of this work was to measure the impulse response function with optimal sensitivity. THEORY AND METHODS:Frequency-swept p...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24934

    authors: Vannesjo SJ,Dietrich BE,Pavan M,Brunner DO,Wilm BJ,Barmet C,Pruessmann KP

    更新日期:2014-08-01 00:00:00

  • Understanding and optimizing the amplitude modulated control for multiple-slice continuous arterial spin labeling.

    abstract::Multiple-slice perfusion imaging by continuous arterial spin labeling (CASL) is made possible by amplitude modulation (AM) of the labeling RF pulse, but perfusion sensitivity is reduced relative to the single-slice technique. A computer model of the Bloch equations for velocity driven adiabatic fast passage was develo...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20604

    authors: Utting JF,Thomas DL,Gadian DG,Helliar RW,Lythgoe MF,Ordidge RJ

    更新日期:2005-09-01 00:00:00

  • Separation and quantification of lactate and lipid at 1.3 ppm by diffusion-weighted magnetic resonance spectroscopy.

    abstract:PURPOSE:To separate the spectrally overlapped lactate and lipid signals at 1.3 ppm using diffusion-weighted magnetic resonance spectroscopy (DW-MRS) based on their large diffusivity difference. METHODS:DW-MRS was applied to the gel phantoms containing lactate and lipid droplets, and to the rat brain tumors. Lactate an...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26144

    authors: Wang AM,Leung GK,Kiang KM,Chan D,Cao P,Wu EX

    更新日期:2017-02-01 00:00:00

  • An analysis of magnetic cross-relaxation between water and methylene protons in a model system.

    abstract::Experiments have been performed to demonstrate and quantify cross-relaxation between water and methylene resonances in a simple model system. Inversion recovery experiments on aqueous solutions of polyethylene glycol produce a transient nuclear Overhauser effect that alters the recovery of the methylene resonance. The...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910090305

    authors: Gore JC,Brown MS,Armitage IM

    更新日期:1989-03-01 00:00:00

  • Doubly tuned local coils for MRI and MRS at 1.5 T.

    abstract::We describe a doubly tuned radiofrequency (RF) local coil probe designed specifically for performing in vivo image-localized spectroscopy. The probe was designed using principles developed in connection with the counter-rotating-current (CRC) and planar-pair loop gap resonators for magnetic resonance imaging (MRI). Th...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910060303

    authors: Grist TM,Jesmanowicz A,Kneeland JB,Froncisz W,Hyde JS

    更新日期:1988-03-01 00:00:00

  • A z-gradient array for simultaneous multi-slice excitation with a single-band RF pulse.

    abstract:PURPOSE:Multi-slice radiofrequency (RF) pulses have higher specific absorption rates, more peak RF power, and longer pulse durations than single-slice RF pulses. Gradient field design techniques using a z-gradient array are investigated for exciting multiple slices with a single-band RF pulse. THEORY AND METHODS:Two d...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27031

    authors: Ertan K,Taraghinia S,Sadeghi A,Atalar E

    更新日期:2018-07-01 00:00:00

  • Low-rank plus sparse compressed sensing for accelerated proton resonance frequency shift MR temperature imaging.

    abstract:PURPOSE:To improve multichannel compressed sensing (CS) reconstruction for MR proton resonance frequency (PRF) shift thermography, with application to MRI-induced RF heating evaluation and MR guided high intensity focused ultrasound (MRgFUS) temperature monitoring. METHODS:A new compressed sensing reconstruction is pr...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27666

    authors: Cao Z,Gore JC,Grissom WA

    更新日期:2019-06-01 00:00:00

  • Magnetization-prepared shells trajectory with automated gradient waveform design.

    abstract:PURPOSE:To develop a fully automated trajectory and gradient waveform design for the non-Cartesian shells acquisition, and to develop a magnetization-prepared (MP) shells acquisition to achieve an efficient three-dimensional acquisition with improved gray-to-white brain matter contrast. METHODS:After reviewing the she...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26863

    authors: Shu Y,Tao S,Trzasko JD,Huston J 3rd,Weavers PT,Bernstein MA

    更新日期:2018-04-01 00:00:00

  • Multivendor implementation and comparison of volumetric whole-brain echo-planar MR spectroscopic imaging.

    abstract:PURPOSE:To assess volumetric proton MR spectroscopic imaging (MRSI) of the human brain on multivendor MRI instruments. METHODS:Echo-planar spectroscopic imaging was developed on instruments from three manufacturers, with matched specifications and acquisition protocols that accounted for differences in sampling perfor...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25510

    authors: Sabati M,Sheriff S,Gu M,Wei J,Zhu H,Barker PB,Spielman DM,Alger JR,Maudsley AA

    更新日期:2015-11-01 00:00:00

  • Comparison of measuring energy metabolism by different (31) P-magnetic resonance spectroscopy techniques in resting, ischemic, and exercising muscle.

    abstract::Alternate methods to quantify mitochondrial activity or function have been extensively used for studying insulin resistance and type 2 diabetes mellitus, namely saturation transfer and phosphocreatine (PCr) recovery. As these methods are in fact determining different parameters, this study aimed to compare saturation ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.23095

    authors: Schmid AI,Schrauwen-Hinderling VB,Andreas M,Wolzt M,Moser E,Roden M

    更新日期:2012-04-01 00:00:00

  • A double-tuned probe for metabolic NMR studies.

    abstract::A double-tuned single coil probe for high field metabolic NMR studies has been designed and tested. The resonant coil is a single-turn of copper foil wound on a quartz cylinder. It is fed by a short length of parallel strip line made of the same material; the feeder is also used as a tuning capacitance. Electrical par...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910230216

    authors: Najim E,Grivet JP

    更新日期:1992-02-01 00:00:00

  • Direct projective time-of-flight NMR angiography within 4s.

    abstract::To enhance contrast between flow and static tissue, NMR projective angiographic methods usually require data subtraction, or alternatively the application of special data processing routines such as the "maximum intensity projection" algorithm. We have successfully developed a direct projection method which yields suf...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910180213

    authors: Matsuda T,Doyle M,Pohost GM

    更新日期:1991-04-01 00:00:00

  • Imaging of the active B1 field in vivo.

    abstract::The authors describe a method for accurate in vivo multislice imaging of the active component of the B1 field which is based on a previously proposed method, which uses the signal intensity ratio of two images measured with different excitation angles, and a repetition time TR 5 > or = 5 T1. The new method essentially...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910350217

    authors: Stollberger R,Wach P

    更新日期:1996-02-01 00:00:00