An analysis of magnetic cross-relaxation between water and methylene protons in a model system.

Abstract:

:Experiments have been performed to demonstrate and quantify cross-relaxation between water and methylene resonances in a simple model system. Inversion recovery experiments on aqueous solutions of polyethylene glycol produce a transient nuclear Overhauser effect that alters the recovery of the methylene resonance. The relevant equations and parameters that describe this effect are identified and their values are explicitly quantified by analyzing the experimental results. It is shown that cross-relaxation is measurable and significant in this system even though there are no strong hydrophilic interactions available to immobilize water. In studies of dog bile, the water and lipid resonances behave in a qualitatively similar fashion, lending support to the contention that cross-relaxation cannot be neglected in solutions of biological macromolecules.

journal_name

Magn Reson Med

authors

Gore JC,Brown MS,Armitage IM

doi

10.1002/mrm.1910090305

subject

Has Abstract

pub_date

1989-03-01 00:00:00

pages

333-42

issue

3

eissn

0740-3194

issn

1522-2594

journal_volume

9

pub_type

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