Abstract:
:This report describes a noninvasive 1H-NMR method for measuring absolute temperatures (+/- 0.2 degrees C) in biological samples and, in particular, in cell culture perfusion systems, utilizing the linear temperature dependence of the water chemical shift relative to the temperature-independent shift of one of the components of the biological medium, e.g., pyruvate, acetate or lactate. The effects of flow on temperature can be monitored and appropriate adjustment of the temperature controller can be made.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Lutz NW,Kuesel AC,Hull WEdoi
10.1002/mrm.1910290120subject
Has Abstractpub_date
1993-01-01 00:00:00pages
113-8issue
1eissn
0740-3194issn
1522-2594journal_volume
29pub_type
杂志文章abstract::When deoxygenated, blood behaves as an effective susceptibility contrast agent. Changes in brain oxygenation can be monitored using gradient-echo echo-planar imaging. With this technique, difference images also demonstrate that blood oxygenation is increased during periods of recovery from respiratory challenge. ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910220117
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abstract::In active catheter tracking, small RF coils are attached to the catheter for localization. For interactive catheter steering at vessel branchings, it is necessary to visualize not only a single point near the catheter tip but also the entire shape and orientation of the catheter's distal end. Therefore, a 35-mm-long t...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.20108
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abstract:PURPOSE:The aim of this study was to develop a technique for rapid collection of chemical exchange saturation transfer images with the saturation varied to modulate signal loss transfer and enhance contrast. METHODS:Multi-echo Length and Offset VARied Saturation (MeLOVARS) divides the saturation pulse of length Tsat i...
journal_title:Magnetic resonance in medicine
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abstract::Recovery of the cerebral cortex after 10 min of cardiac arrest was studied in rat using noninvasive MRI techniques. The apparent diffusion coefficient (ADC) of brain water was imaged to document reversal of the metabolic impairment. Perfusion-weighted imaging and blood oxygen level dependent (BOLD) imaging were perfor...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910390516
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abstract::We developed a live high-field multiple-mouse magnetic resonance imaging method to increase the throughput of imaging studies involving large numbers of mice. Phantom experiments were performed in 7 shielded radiofrequency (RF) coils for concurrent imaging on a 7 Tesla MRI scanner outfitted with multiple transmit and ...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.20683
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abstract::Applications of fMRI in functional brain imaging are mainly confined to single subject designs, prohibiting the assessment of subject or group by condition interactions (i.e., differential activations) or areas of conjoint activation. In this paper a framework for fMRI group designs, using statistical parametric mappi...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.1910380502
更新日期:1997-11-01 00:00:00
abstract::Frequency-modulated (FM) pulses have practical advantages for spin-echo experiments, such as the ability to produce a broadband pi rotation, with an inhomogeneous radiofrequency (RF) field. However, such use leads to a nonlinear phase of the transverse magnetization, which is why FM pulses like the hyperbolic secant (...
journal_title:Magnetic resonance in medicine
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abstract:PURPOSE:To investigate the influence of transcytolemmal water exchange on estimates of tissue microstructural parameters derived from diffusion MRI using conventional PGSE and IMPULSED methods. METHODS:Computer simulations were performed to incorporate a broad range of intracellular water life times τin (50-∞ ms), cel...
journal_title:Magnetic resonance in medicine
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abstract:PURPOSE:To study the feasibility of black-blood contrast in native T1 mapping for reduction of partial voluming at the blood-myocardium interface. METHODS:A saturation pulse prepared heart-rate-independent inversion recovery (SAPPHIRE) T1 mapping sequence was combined with motion-sensitized driven-equilibrium (MSDE) b...
journal_title:Magnetic resonance in medicine
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abstract:PURPOSE:Diabetic nephropathy (DN) is the leading cause of renal failure; however, current clinical tests are insufficient for assessing this disease. DN is associated with changes in renal metabolites, so we evaluated the utility of chemical exchange saturation transfer (CEST) imaging to detect changes characteristic o...
journal_title:Magnetic resonance in medicine
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journal_title:Magnetic resonance in medicine
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更新日期:1997-12-01 00:00:00
abstract::Parameter-selective imaging for tissue characterization is performed at low magnetic fields (0.24-0.28 T) employing echo trains with a large number of echoes (less than or equal to 50), high-power pulses, and the projection reconstruction method. Preprocessing of the raw echoes is important for the quality of the echo...
journal_title:Magnetic resonance in medicine
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更新日期:1986-06-01 00:00:00
abstract::The long readout times of single-shot acquisitions and the high field strengths desired for functional MRI (fMRI) using blood oxygenation level-dependent (BOLD) contrast make functional scans sensitive to magnetic field inhomogeneity. If it is not corrected during image reconstruction, field inhomogeneity can cause ge...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.20079
更新日期:2004-06-01 00:00:00
abstract::The complexity of biologic tissues, with multiple compartments each with its own diffusion and relaxation properties, requires complex formalisms to model water signal in most magnetic resonance imaging or magnetic resonance spectroscopy experiments. In this article, we describe a magnetic susceptibility-induced shift...
journal_title:Magnetic resonance in medicine
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更新日期:2005-07-01 00:00:00
abstract:PURPOSE:We sought to develop and test a clinically feasible 1-point Dixon, three-dimensional (3D) radial acquisition strategy to create isotropic 3D MR images of (129)Xe in the airspaces, barrier, and red blood cells (RBCs) in a single breath. The approach was evaluated in healthy volunteers and subjects with idiopathi...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25675
更新日期:2016-04-01 00:00:00
abstract::The signals of water in the different compartments of rat sciatic nerve are resolved in the (2)H double-quantum-filtered NMR spectrum, due to their different quadrupolar splittings and relaxation rates. This resolution allowed the independent measurement of the water diffusion coefficients in the different compartment...
journal_title:Magnetic resonance in medicine
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更新日期:1999-09-01 00:00:00
abstract:PURPOSE:To develop a method based on fat-water transition region extraction (TREE) for robust fat-water separation and quantification in challenging scenarios, including low signal-to-noise ratio (SNR), fast changing B0 field, and disjointed anatomies. THEORY AND METHODS:In TREE method, the phasor solutions of each pi...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27710
更新日期:2019-07-01 00:00:00
abstract::Endogenous glucose production (EGP), gluconeogenic and glycogenolytic fluxes by analysis of a single (2)H-NMR spectrum is demonstrated with 6-hr and 24-hr fasted rats. Animals were administered [1-(2)H, 1-(13)C]glucose, a novel tracer of glucose turnover, and (2)H(2)O. Plasma glucose enrichment from both tracers was q...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.22062
更新日期:2009-09-01 00:00:00
abstract::Excitation by conventional B1 pulses in surface coil chemical-shift imaging experiments yields resonance intensities that vary greatly with position. B1-compensated semi-selective pulses overcome much of this problem. These pulses are employed for excitation and refocusing in 1H NMR spectroscopic localization in the i...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.1910250118
更新日期:1992-05-01 00:00:00
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journal_title:Magnetic resonance in medicine
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journal_title:Magnetic resonance in medicine
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journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10104
更新日期:2002-03-01 00:00:00
abstract::A new decoupling sequence, PBAR, is described for broadband heteronuclear decoupling in vivo in humans at 1.5T. The sequence uses non-adiabatic, frequency- and amplitude-modulated inversion pulses designed to minimize decoupling sidebands at low applied gammaB(2) RF field levels and to cover only the narrow range of r...
journal_title:Magnetic resonance in medicine
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更新日期:2001-02-01 00:00:00
abstract:PURPOSE:To investigate the heating induced by (pseudo)-continuous arterial spin labeling ((p)CASL) sequences in vivo at 9.4T and to evaluate the benefit of a dedicated labeling coil. METHODS:Temperature was measured continuously in the brain, neck, and rectum of 9 rats with fiber-optic temperature probes while running...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.27931
更新日期:2020-01-01 00:00:00
abstract::The mechanics of the macrocirculation are examined as a basis for imaging blood flow within the system. The macrocirculation is defined as that part of the circulation in which inertial forces are not negligible compared to viscous forces and as such in human subjects comprises the heart and large blood vessels. Becau...
journal_title:Magnetic resonance in medicine
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更新日期:1990-05-01 00:00:00
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journal_title:Magnetic resonance in medicine
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更新日期:2021-02-01 00:00:00
abstract:PURPOSE:MR elastography (MRE) of the brain is being explored as a biomarker of neurodegenerative disease such as dementia. However, MRE measures for healthy brain have varied widely. Differing wave delivery methodologies may have influenced this, hence finite element-based simulations were performed to explore this pos...
journal_title:Magnetic resonance in medicine
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abstract::Phase-contrast (PC) MRI is a noninvasive method for imaging blood and tissue velocity. PC experiments are typically segmented into many cardiac cycles in order to obtain sufficient spatial and temporal resolution, and thus require a gating signal to properly combine the data from multiple cardiac cycles. Although the ...
journal_title:Magnetic resonance in medicine
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abstract::Maximal intensity projection (MIP) is routinely used to view MRA and other volumetric angiographic data. The straightforward implementation of MIP is ray casting that traces a volumetric data set in a computationally expensive manner. This article reports a fast MIP algorithm using shear warp factorization and reduced...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.10114
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