Abstract:
:A new decoupling sequence, PBAR, is described for broadband heteronuclear decoupling in vivo in humans at 1.5T. The sequence uses non-adiabatic, frequency- and amplitude-modulated inversion pulses designed to minimize decoupling sidebands at low applied gammaB(2) RF field levels and to cover only the narrow range of resonance offsets encountered in practice. The offset dependence of the decoupling efficiency of PBAR is demonstrated and compared to the conventional WALTZ-4 sequence. At the same average power levels, PBAR had slightly reduced bandwidth but significantly less intense decoupling sidebands. Applications of PBAR are shown in vivo in the human brain both for (31)P and natural abundance (13)C spectroscopy using volume decoupling coils. The PBAR sequence allows whole brain [(1)H]-[13]C decoupling to be performed at 1.5T with a standard head coil within FDA guidelines for RF power deposition. Magn Reson Med 45:226-232, 2001.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Barker PB,Golay X,Artemov D,Ouwerkerk R,Smith MA,Shaka AJdoi
10.1002/1522-2594(200102)45:2<226::aid-mrm1031>3.0subject
Has Abstractpub_date
2001-02-01 00:00:00pages
226-32issue
2eissn
0740-3194issn
1522-2594pii
10.1002/1522-2594(200102)45:2<226::AID-MRM1031>3.0journal_volume
45pub_type
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