Abstract:
PURPOSE:To characterize the fundamental limits of MRI near metallic implants on RF excitation, frequency encoding, and chemical shift-encoding water-fat separation. METHODS:Multicomponent three-dimensional (3D) digital models of a total hip and a total knee replacement were used to construct material-specific susceptibility maps. The fundamental limits and spatial relationship of imaging near metallic prostheses were investigated as a function of distance from the prosthetic surface by calculating 3D field map perturbations using a well-validated k-space based dipole kernel. RESULTS:Regions limited by the bandwidth of RF excitation overlap substantially with those fundamentally limited by frequency encoding. Rapid breakdown of water-fat separation occurs once the intravoxel off-resonance exceeds ∼6 ppm over a full range of fat fractions (0%-100%) and SNR (5-100). CONCLUSION:Current 3D multispectral imaging methods would not benefit greatly from exciting spins beyond ±12 kHz despite the presence of signal that lies outside of this range from tissue directly adjacent to the metallic implants. Methods such as phase encoding in all three spatial dimensions are necessary to spatially resolve spins beyond an excitation bandwidth of ±12 kHz. The approach described in this study provides a benchmark for the capabilities of current imaging techniques to guide development of new MRI methods for imaging near metal.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Smith MR,Artz NS,Wiens C,Hernando D,Reeder SBdoi
10.1002/mrm.25540subject
Has Abstractpub_date
2015-12-01 00:00:00pages
1564-73issue
6eissn
0740-3194issn
1522-2594journal_volume
74pub_type
杂志文章abstract::MRS has considerable potential for the measurement of drug pharmacokinetics in vivo. In this study single- and double-resonance (31)P MRS was used to investigate the biodistribution, pharmacokinetics, and metabolism of ifosfamide following administration of 500 mg/kg ifosfamide in guinea pigs. (1)H-decoupling was foun...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10540
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abstract::Quantitative artificial neural network analysis for 1550 ex vivo 31P nuclear magnetic resonance spectra from hypothermically reperfused pig livers was assessed. These spectra show wide ranges of metabolite concentrations and have been analyzed using metabolite prior knowledge based lineshape fitting analysis which had...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910380522
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journal_title:Magnetic resonance in medicine
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journal_title:Magnetic resonance in medicine
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更新日期:2016-07-01 00:00:00
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journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.21738
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journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.21711
更新日期:2008-09-01 00:00:00
abstract::A new fully automatic algorithm for the segmentation of the brain and total intracranial cerebrospinal fluid (CSF) from T(1)-weighted volume MRI scans of the head, called Exbrain v.2, is described. The algorithm was developed in the context of serial intracranial volumetry. A brain mask obtained using a previous versi...
journal_title:Magnetic resonance in medicine
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更新日期:2003-05-01 00:00:00
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journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27342
更新日期:2018-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/mrm.24905
更新日期:2014-07-01 00:00:00
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journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24378
更新日期:2013-05-01 00:00:00
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journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
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更新日期:1999-10-01 00:00:00
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journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.28084
更新日期:2020-06-01 00:00:00
abstract::In some dynamic applications of MRI, only a part of the field-of-view (FOV) actually undergoes dynamic changes. A class of methods, called reduced-FOV (rFOV) methods, convert the knowledge that some part of the FOV is static or not very dynamic into an increase in temporal resolution for the dynamic part, or into a re...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/(sici)1522-2594(200004)43:4<549::aid-mrm9>
更新日期:2000-04-01 00:00:00
abstract:PURPOSE:Previous studies have associated low pH in intervertebral discs (IVDs) with discogenic back pain. The purpose of this study was to determine whether quantitative CEST (qCEST) MRI can be used to detect pH changes in IVDs in vivo. METHODS:The exchange rate ksw between glycosaminoglycan (GAG) protons and water pr...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.26457
更新日期:2016-12-01 00:00:00
abstract:PURPOSE:In diffusion MRI, the actual b-value played out on the scanner may deviate from the nominal value due to magnetic field imperfections. A simple image-based correction method for this problem is presented. METHODS:The apparent diffusion constant (ADC) of a water phantom was measured voxel-wise along 64 diffusio...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.28078
更新日期:2020-06-01 00:00:00
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journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25436
更新日期:2015-08-01 00:00:00
abstract::Fluid-attenuated inversion recovery (FLAIR) images obtained during the administration of supplemental oxygen demonstrate a hyperintense signal within the cerebrospinal fluid (CSF) that is likely caused by T1 changes induced by paramagnetic molecular oxygen. Previous studies demonstrated a linear relationship between t...
journal_title:Magnetic resonance in medicine
pub_type: 临床试验,杂志文章
doi:10.1002/mrm.20546
更新日期:2005-07-01 00:00:00
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journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910060111
更新日期:1988-01-01 00:00:00
abstract::Alternate methods to quantify mitochondrial activity or function have been extensively used for studying insulin resistance and type 2 diabetes mellitus, namely saturation transfer and phosphocreatine (PCr) recovery. As these methods are in fact determining different parameters, this study aimed to compare saturation ...
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doi:10.1002/mrm.23095
更新日期:2012-04-01 00:00:00
abstract::Echo-planar spectroscopic imaging (EPSI) can be used for fast spectroscopic imaging of water and fat resonances at high resolution to improve structural and functional imaging. Because of the use of oscillating gradients during the free induction decay (FID), spectra obtained with EPSI are often degraded by Nyquist gh...
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abstract::In vivo echo-planar MR imaging was used to measure apparent diffusion coefficients (ADC) of cerebral tissues in a comprehensive noninvasive evaluation of early ischemic brain damage induced by occlusion of the middle cerebral artery (MCA) in a cat model of acute regional stroke. Within 10 min after arterial occlusion,...
journal_title:Magnetic resonance in medicine
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journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25602
更新日期:2016-02-01 00:00:00
abstract::Given its greater availability and lower cost, (129) Xe apparent diffusion coefficient (ADC) MRI offers an alternative to (3) He ADC MRI. To demonstrate the feasibility of hyperpolarized (129) Xe ADC MRI, we present results from healthy volunteers (HV), chronic obstructive pulmonary disease (COPD) subjects, and age-ma...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
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更新日期:2011-04-01 00:00:00
abstract::Phosphorus NMR can measure myocardial tissue pH from the chemical shift of inorganic phosphate (Pi) in isolated buffer-perfused hearts, but in vivo the Pi peak originating from the myocardium is obscured by the resonance of 2,3-diphosphoglycerate (DPG) in the blood, making pH difficult to determine. Taking advantage o...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910170209
更新日期:1991-02-01 00:00:00
abstract::We applied MRI to the in vivo detection of spontaneous colorectal tumors in a unique mouse model, the Fox Chase Cancer Center (FCCC) ApcMIN mouse. Unlike other Min (multiple intestinal neoplasia) strains, FCCC ApcMIN animals develop an appreciable number of tumors in the large intestine, which makes them an appropriat...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.20175
更新日期:2004-09-01 00:00:00
abstract::High-quality, high-resolution, proton-decoupled natural-abundance 13C NMR spectra have been obtained in vitro at 100.6 MHz from unprocessed human pathology specimens of tumors and adjacent nonneoplastic control tissues from lung, colon, and prostate. In these preliminary studies, specific molecular parameters were ide...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910070403
更新日期:1988-08-01 00:00:00
abstract::Elastase-induced changes in lung morphology and function were detected in spontaneously breathing rats using conventional proton MRI at 4.7 T. A single dose of porcine pancreatic elastase (75 U/100 g body weight) or vehicle (saline) was administered intratracheally (i.t.) to male Brown Norway (BN) rats. MRI fluid sign...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21051
更新日期:2006-12-01 00:00:00
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journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
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更新日期:2006-11-01 00:00:00
abstract::The proton T(1) was measured at 132 μT in ex vivo prostate tissue specimens from radical prostatectomies of 35 patients with prostate cancer. Each patient provided two specimens. The NMR and MRI measurements involved proton repolarization, a field of typically 150 mT and detection of the 5.6-kHz signal with a supercon...
journal_title:Magnetic resonance in medicine
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更新日期:2012-04-01 00:00:00
abstract::Pattern recognition techniques (factor analysis and neural networks) were used to investigate and classify human brain tumors based on the 1H NMR spectra of chemically extracted biopsies (n = 118). After removing information from lactate (because of variable ischemia times), unsupervised learning suggested that the sp...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.1910390604
更新日期:1998-06-01 00:00:00