Abstract:
:Applications of fMRI in functional brain imaging are mainly confined to single subject designs, prohibiting the assessment of subject or group by condition interactions (i.e., differential activations) or areas of conjoint activation. In this paper a framework for fMRI group designs, using statistical parametric mapping, is introduced. It is generally believed that intersubject averaging, which requires spatial normalization and smoothing, will decrease the effective spatial resolution of fMRI or its sensitivity. A subcortical activation of the lateral geniculate nucleus (LGN) was therefore chosen to demonstrate the feasibility and power of intersubject averaging in the context of fMRI. Seven volunteers were studied, while looking at a blank screen or radially moving dots. LGN activation was demonstrated in all single subject analyses and in the group analysis.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Büchel C,Turner R,Friston Kdoi
10.1002/mrm.1910380502subject
Has Abstractpub_date
1997-11-01 00:00:00pages
691-4issue
5eissn
0740-3194issn
1522-2594journal_volume
38pub_type
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journal_title:Magnetic resonance in medicine
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journal_title:Magnetic resonance in medicine
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journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.1242
更新日期:2001-10-01 00:00:00
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更新日期:2013-09-01 00:00:00
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journal_title:Magnetic resonance in medicine
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更新日期:2007-11-01 00:00:00
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journal_title:Magnetic resonance in medicine
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journal_title:Magnetic resonance in medicine
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