The role of membrane water permeability in characterization of pathologically altered human stomach tissues: NMR studies.

Abstract:

:Comparative NMR studies of normal and pathologically altered human stomach tissues were performed on the basis of proton T1 relaxation time measurements in the presence of high external concentrations of relaxation (contrast) agents manganese ethylenediaminetetraacetic acid (Mn-EDTA) and gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA). Diffusion permeability of the cell membrane to water, Pd, was determined by measuring the longest proton T1 component sensitive to the exchange of water molecules through the cell membrane. Pathologically altered tissues showed substantially higher (2 to 10 times) average cell membrane permeabilities to water.

journal_name

Magn Reson Med

authors

Srejić R,Popov DV,Boricić I,Zuvela M

doi

10.1002/mrm.1910150313

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

469-74

issue

3

eissn

0740-3194

issn

1522-2594

journal_volume

15

pub_type

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