Abstract:
:Quantitative diffusion measurements were performed in tumors arising from inoculation of nude mice with two human breast cancer cell lines (MCF7 and T47D) to evaluate the specificity of this technique for characterizing solid tumors. ADC maps were compared to histology and correlated well with gross tumor morphology. Measured ADCs were highly specific for viable and necrotic tumor in the five T47D tumors included in this study (P < 0.02), while only two of the five MCF7 tumors studied developed distinguishable areas of necrosis. No statistically significant difference was observed in ADCs from viable tumor between the different cell lines (P > 0.05).
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Maier CF,Paran Y,Bendel P,Rutt BK,Degani Hdoi
10.1002/mrm.1910370417subject
Has Abstractpub_date
1997-04-01 00:00:00pages
576-81issue
4eissn
0740-3194issn
1522-2594journal_volume
37pub_type
杂志文章abstract:PURPOSE:Vulnerable atherosclerotic plaques are structurally weak and prone to rupture, presumably due to local oxidative stress. Redox active iron is linked to oxidative stress and the aim of this study was to investigate the distribution of Fe(III) in carotid plaques and its relation to vulnerability for rupture. MET...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24687
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:The purpose of this study is to increase the robustness of MR fingerprinting (MRF) toward subject motion. METHODS:A novel reconstruction algorithm, MOtion insensitive MRF (MORF), was developed, which uses an iterative reconstruction based retrospective motion correction approach. Each iteration loops through t...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27227
更新日期:2018-12-01 00:00:00
abstract::The investigation of flow behavior in coronary arteries is of great importance for an understanding of heart failure and heart regulation mechanisms. The purpose of the present study was to demonstrate that flow velocity can be quantified in the coronary arteries of the isolated rat heart with high-resolution phase co...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10563
更新日期:2003-09-01 00:00:00
abstract::The experiments reported herein are the first MRI investigations of the orientational dependence of T(2) relaxation in articular cartilage at microscopic resolution over the 360 degrees angular space. For each of six canine cartilage specimens, 48 independent T(2)-weighted proton images were acquired for 12 different ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10216
更新日期:2002-09-01 00:00:00
abstract:PURPOSE:To examine the detection sensitivity for the rapidly exchanging hydroxyl protons of D-glucose using the recently developed on-resonance variable delay multi-pulse (onVDMP) chemical exchange saturation transfer (CEST) technique. METHODS:The onVDMP method was applied for the detection of water signal changes upo...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27364
更新日期:2019-01-01 00:00:00
abstract::Quantitative estimation of T1 is a challenging but important task inherent to many clinical applications. The most commonly used paradigm for estimating T1 in vivo involves performing a sequence of spoiled gradient-recalled echo acquisitions at different flip angles, followed by fitting of an exponential model to the ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24401
更新日期:2013-06-01 00:00:00
abstract:PURPOSE:To assess volumetric proton MR spectroscopic imaging (MRSI) of the human brain on multivendor MRI instruments. METHODS:Echo-planar spectroscopic imaging was developed on instruments from three manufacturers, with matched specifications and acquisition protocols that accounted for differences in sampling perfor...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25510
更新日期:2015-11-01 00:00:00
abstract::It has been suggested that orientational changes in the collagen network of articular cartilage account for the depthwise T2 anisotropy of MRI through the magic angle effect. To investigate the relationship between laminar T2 appearance and collagen organization (anisotropy), bovine osteochondral plugs (N = 9) were T2...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1218
更新日期:2001-09-01 00:00:00
abstract::Spin-echo images of 10 myocardial infarcts in nine mini-pigs were obtained at 30 h, 3 days, and approximately 10 days postinfarction. Infarcts were not detected at all at 30 h in five out of five cases examined. At 3 days postembolization (six cases) one infarct was certainly detected, whilst at 10 days (nine cases) a...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910050302
更新日期:1987-09-01 00:00:00
abstract::At high magnetic fields the performance of a volume-type body coil inside a human sized MR-scanner is influenced by the waveguide action of the scanner's bore. This can result in undesirable strong radio frequency fields B1+) outside the coil's target volume. A radio frequency (RF) transmit system, exploiting this wav...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24496
更新日期:2013-09-01 00:00:00
abstract:PURPOSE:To achieve highly accelerated submillimeter resolution T 2 -weighted functional MRI at 7T by developing a three-dimensional gradient and spin echo imaging (GRASE) with inner-volume sel...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.28589
更新日期:2020-11-24 00:00:00
abstract:PURPOSE:Reliable monitoring of tissue nicotinamide adenine dinucleotide (NAD+ ) concentration may provide insights on its roles in normal and pathological aging. In the present study, we report a 1 H MRS pulse sequence for the in vivo, localized 1 H MRS detection of NAD+ from the human brain. METHODS:Studies were carr...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27971
更新日期:2020-03-01 00:00:00
abstract::Spinal cord (SC) motion is thought to be the dominant source of error in current diffusion and spinal functional MRI (fMRI) methods. However, until now, such motion has not been well characterized in three dimensions. While previous studies have predominantly examined motion in the superior/inferior (S/I) direction, t...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21260
更新日期:2007-07-01 00:00:00
abstract::A type of local coil (or surface coil) for magnetic resonance imaging and spectroscopy is described in which two circular loops of the same diameter are disposed axially with respect to each other and in which counter rotating currents (CRC) are supported in the two loops. This type of coil has been used for localized...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910030412
更新日期:1986-08-01 00:00:00
abstract::Formation of ternary complexes between Gd-DTPA, Gd-DTPA-BMA, and Gd-DOTA, used as contrast enhancement agents in MRI and the endogenously available carbonate and phosphate ions, has been demonstrated. The extent of ternary complex formation and its effect on the proton relaxation, measured at 9 MHz, rates is negligibl...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910380120
更新日期:1997-07-01 00:00:00
abstract::The interactive use of magnetic resonance imaging (MRI) techniques is increasing in operating theaters. A study was performed on 17 male company volunteers to assess the neurobehavioral effects of exposure to magnetic fields from a 1.5 Tesla MRI system. The subjects' neurobehavioral performances on a neurobehavioral t...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10604
更新日期:2003-10-01 00:00:00
abstract::Typically, MR-elastography (MRE) encodes the propagation of monochromatic acoustic waves in the MR-phase images via sinusoidal gradients characterized by a detection frequency equal to the frequency of the mechanical vibration. Therefore, the echo time of a conventional MRE sequence is typically longer than the vibrat...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22124
更新日期:2009-11-01 00:00:00
abstract::To obtain a better understanding of the mechanisms underlying early changes in the brain water apparent diffusion coefficient (ADC) observed in cerebral ischemia, dynamic changes in the ADC of water and in the energy status were measured at postnatal day 8 or 9 in neonatal rat brains after cardiac arrest using 1H MRS/...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910360110
更新日期:1996-07-01 00:00:00
abstract::Stejskal and Tanner's ingenious pulsed field gradient design from 1965 has made diffusion NMR and MRI the mainstay of most studies seeking to resolve microstructural information in porous systems in general and biological systems in particular. Methods extending beyond Stejskal and Tanner's design, such as double diff...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章,评审
doi:10.1002/mrm.25901
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:MUSSELS is a one-step iterative reconstruction method for multishot diffusion weighted (msDW) imaging. The current work presents an efficient implementation, termed IRLS MUSSELS, that enables faster reconstruction to enhance its utility for high-resolution diffusion MRI studies. METHODS:The recently proposed M...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.28090
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:In contrast to conventional linear gradients, gradient coil arrays with arbitrary spatial dependency might experience strong mutual coupling. Although conventional gradient power amplifiers with feedback loop might compensate the effect of coupling, required voltages for the compensation are generally unknown a...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27768
更新日期:2019-09-01 00:00:00
abstract::Direct measurement of neural currents by means of MRI can potentially open a high temporal resolution (10-100 ms) window applicable for monitoring dynamics of neuronal activity without loss of the high spatial resolution afforded by MRI. Previously, we have shown that the alternating balanced steady state imaging affo...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.23105
更新日期:2012-05-01 00:00:00
abstract:PURPOSE:MR safety at 7 Tesla relies on accurate numerical simulations of transmit electromagnetic fields to fully assess local specific absorption rate (SAR) safety. Numerical simulations for SAR safety are currently performed using models of healthy patients. These simulations might not be useful for estimating SAR in...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25653
更新日期:2016-01-01 00:00:00
abstract::A novel method for reducing the rf power requirements of selective pulses employed for z magnetization slice inversion in localized NMR spectroscopy is presented. Following slice preparation by the use of frequency-incremented sinc pulses, the slice gradient is reduced, which narrows the frequency width of the slice. ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910050610
更新日期:1987-12-01 00:00:00
abstract::The use of the minimum stored energy current density map-based methodology of designing closed-bore symmetric superconducting magnets was described recently. The technique is further developed to cater for the design of interventional-type MRI systems, and in particular open symmetric magnets of the double-doughnut co...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22189
更新日期:2010-01-01 00:00:00
abstract::Advances in modern magnetic resonance imaging (MRI) pulse sequences have enabled clinically practical cortical bone imaging. Human cortical bone is known to contain a distribution of T(1) and T(2) components attributed to bound and pore water, although clinical imaging approaches have yet to discriminate bound from po...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24186
更新日期:2012-12-01 00:00:00
abstract::High-order radiofrequency transmitter coils are described that permit, in the context of NMR imaging, a knowledgeable trade-off between coil complexity and the degree of inhomogeneity over a specified volume of space. A mathematical formulation of high-order coils is developed for an axially symmetric polarizing dc fi...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910030108
更新日期:1986-02-01 00:00:00
abstract::In the ongoing quest for faster imaging and higher spatial resolution, several methods have been developed to speed up data acquisition by incorporating prior information about the object being imaged. This study shows that many of these methods can be integrated into a single common equation. The unified framework pr...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1242
更新日期:2001-10-01 00:00:00
abstract:PURPOSE:Sickle cell anemia is a blood disorder that alters the morphology and the oxygen affinity of the red blood cells. Cerebral oxygen extraction fraction measurements using quantitative BOLD contrast have been used for assessing inadequate oxygen delivery and the subsequent risk of ischemic stroke in sickle cell an...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.28668
更新日期:2021-01-21 00:00:00
abstract:PURPOSE:In this study, an iterative k-t principal component analysis (PCA) algorithm with nonrigid frame-to-frame motion correction is proposed for dynamic contrast-enhanced three-dimensional perfusion imaging. METHODS:An iterative k-t PCA algorithm was implemented with regularization using training data corrected for...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24894
更新日期:2014-07-01 00:00:00