High-resolution 1 H-MRSI of the brain using short-TE SPICE.

Abstract:

PURPOSE:To improve signal-to-noise ratio (SNR) for high-resolution spectroscopic imaging using a subspace-based technique known as SPectroscopic Imaging by exploiting spatiospectral CorrElation (SPICE). METHODS:The proposed method is based on a union-of-subspaces model of MRSI signals, which exploits the partial separability properties of water, lipid, baseline and metabolite signals. Enabled by this model, a special scheme is used for accelerated data acquisition, which includes a double-echo CSI component used to collect a "training" dataset (for determination of the basis functions) and a short-TE EPSI component used to collect a sparse "imaging" dataset (for determination of the overall spatiospectral distributions). A set of signal processing algorithms are developed to remove the water and lipid signals and jointly reconstruct the metabolite and baseline signals. RESULTS:In vivo 1 H-MRSI results show that the proposed method can effectively remove the remaining water and lipid signals from sparse MRSI data acquired at 20 ms TE. Spatiospectral distributions of metabolite signals at 2 mm in-plane resolution with good SNR were obtained in a 15.5 min scan. CONCLUSIONS:The proposed method can effectively remove nuisance signals and reconstruct high-resolution spatiospectral functions from sparse data to make short-TE SPICE possible. The method should prove useful for high-resolution 1 H-MRSI of the brain. Magn Reson Med 77:467-479, 2017. © 2016 International Society for Magnetic Resonance in Medicine.

journal_name

Magn Reson Med

authors

Ma C,Lam F,Ning Q,Johnson CL,Liang ZP

doi

10.1002/mrm.26130

subject

Has Abstract

pub_date

2017-02-01 00:00:00

pages

467-479

issue

2

eissn

0740-3194

issn

1522-2594

journal_volume

77

pub_type

杂志文章
  • Whole-heart steady-state free precession coronary artery magnetic resonance angiography.

    abstract::Current implementations of coronary artery magnetic resonance angiography (MRA) suffer from limited coverage of the coronary arterial system. Whole-heart coronary MRA was implemented based on a free-breathing steady-state free-precession (SSFP) technique with magnetization preparation. The technique was compared to a ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10653

    authors: Weber OM,Martin AJ,Higgins CB

    更新日期:2003-12-01 00:00:00

  • 3D-printed Shepp-Logan phantom as a real-world benchmark for MRI.

    abstract:PURPOSE:As prescribed and reliable geometrical entities, phantoms have served as indispensable validation tools in a variety of MR-related topics. Though a number of phantoms have been conceived, certain applications may warrant highly customized geometries. The purpose of this study was to demonstrate the expediency o...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25593

    authors: Kasten JA,Vetterli T,Lazeyras F,Van De Ville D

    更新日期:2016-01-01 00:00:00

  • Phase constrained encoding (PACE): a technique for MRI in large static field inhomogeneities.

    abstract::In spin echo imaging, magnetization is assigned to a location defined by its frequency of rotation. In the presence of a static magnetic field inhomogeneity, however, this location does not correspond to the true location of the magnetization. This paper describes a magnetic resonance imaging technique called phase co...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910330407

    authors: Kim JK,Plewes DB,Henkelman RM

    更新日期:1995-04-01 00:00:00

  • Evaluation of acute brain edema using quantitative magnetic resonance imaging: effects of pretreatment with dexamethasone.

    abstract::We developed a quantitative magnetic resonance imaging method to permit a rapid assessment of brain water content during osmotic brain edema produced by intraperitoneal (ip) injection of distilled water. Fifteen minutes after water injection, the normalized mean image intensity (MIn) from a spin-echo pulse sequence (T...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910240107

    authors: Olson JE,Katz-Stein A,Reo NV,Jolesz FA

    更新日期:1992-03-01 00:00:00

  • Imaging oxygen tension in liver and spleen by 19F NMR.

    abstract::19F NMR imaging of the perfluorocarbon emulsion Fluosol has been used to study regional variations in oxygen tension in rat liver and spleen. We have used the linear dependence of spin lattice relaxation rate (1/T1) on the partial oxygen pressure (pO2) of Fluosol to determine the oxygen tension in the reticuloendothel...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910290405

    authors: Holland SK,Kennan RP,Schaub MM,D'Angelo MJ,Gore JC

    更新日期:1993-04-01 00:00:00

  • Detection of subnanotesla oscillatory magnetic fields using MRI.

    abstract:PURPOSE:Direct mapping of neuronal currents using MRI would have fundamental impacts on brain functional imaging. Previous reports indicated that the stimulus-induced rotary saturation (SIRS) mechanism had the best potential of direct detection of neural oscillations; however, it lacked the high-sensitivity level neede...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25553

    authors: Jiang X,Sheng J,Li H,Chai Y,Zhou X,Wu B,Guo X,Gao JH

    更新日期:2016-02-01 00:00:00

  • Free breathing three-dimensional late gadolinium enhancement cardiovascular magnetic resonance using outer volume suppressed projection navigators.

    abstract:PURPOSE:To develop a three-dimensional, free-breathing, late gadolinium enhancement (3D FB-LGE) cardiovascular magnetic resonance (CMR) technique, and to compare it with clinically used two-dimensional breath-hold LGE (2D BH-LGE). METHODS:The proposed 3D FB-LGE method consisted of inversion preparation, inversion dela...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26234

    authors: Menon RG,Miller GW,Jeudy J,Rajagopalan S,Shin T

    更新日期:2017-04-01 00:00:00

  • Evidence that both fast and slow water ADC components arise from intracellular space.

    abstract::Evaluation of water diffusion in the brain has revealed both fast- and slow-diffusing water populations. It has been suggested that these populations represent extra- and intracellular water, respectively. We have identified and characterized both populations in the intracellular space of the Xenopus oocyte. We have a...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10301

    authors: Sehy JV,Ackerman JJ,Neil JJ

    更新日期:2002-11-01 00:00:00

  • Accelerated cardiac magnetic resonance imaging in the mouse using an eight-channel array at 9.4 Tesla.

    abstract::MRI has become an important tool to noninvasively assess global and regional cardiac function, infarct size, or myocardial blood flow in surgically or genetically modified mouse models of human heart disease. Constraints on scan time due to sensitivity to general anesthesia in hemodynamically compromised mice frequent...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22605

    authors: Schneider JE,Lanz T,Barnes H,Stork LA,Bohl S,Lygate CA,Ordidge RJ,Neubauer S

    更新日期:2011-01-01 00:00:00

  • Optimization of survey protocols for MRI.

    abstract::A method for evaluating the sensitivity of MRI protocols to changes in an arbitrary number of tissue parameters over a broad range of parameter values is presented. This analysis is useful for choosing an optimal basis set of images for either a "survey" protocol or tissue segmentation algorithms. A survey protocol is...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910130202

    authors: McVeigh ER,Henkelman RM,Bronskill MJ

    更新日期:1990-02-01 00:00:00

  • Rapid T1 mapping of mouse myocardium with saturation recovery Look-Locker method.

    abstract::Dynamic contrast-enhanced MRI using gadolinium or manganese provides unique characterization of myocardium and its pathology. In this study, an electrocardiography (ECG) triggered saturation recovery Look-Locker method was developed and validated for fast cardiac T(1) mapping in small animal models. By sampling the in...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22544

    authors: Li W,Griswold M,Yu X

    更新日期:2010-11-01 00:00:00

  • Multi-gradient echo with susceptibility inhomogeneity compensation (MGESIC): demonstration of fMRI in the olfactory cortex at 3.0 T.

    abstract::Short image acquisition times and sensitivity to magnetic susceptibility favor the use of gradient echo imaging methods in functional MRI (fMRI). However, magnetic susceptibility effects attributed to air-tissue interfaces also lead to severe signal loss in images of the large inferior frontal and lateral temporal cor...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910370304

    authors: Yang QX,Dardzinski BJ,Li S,Eslinger PJ,Smith MB

    更新日期:1997-03-01 00:00:00

  • Robust water fat separated dual-echo MRI by phase-sensitive reconstruction.

    abstract:PURPOSE:The purpose of this work was to develop and evaluate a robust water-fat separation method for T1-weighted symmetric two-point Dixon data. THEORY AND METHODS:A method for water-fat separation by phase unwrapping of the opposite-phase images by phase-sensitive reconstruction (PSR) is introduced. PSR consists of ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26488

    authors: Romu T,Dahlström N,Leinhard OD,Borga M

    更新日期:2017-09-01 00:00:00

  • In vivo visualization of myelin water in brain by magnetic resonance.

    abstract::We exploit the intrinsic difference in magnetic resonance spin-spin relaxation time, T2, between water associated with myelin sheaths and water in other central nervous system tissue in order to measure myelin water content within any region of an image or to generate indirectly a myelin map of the brain. In normal vo...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910310614

    authors: MacKay A,Whittall K,Adler J,Li D,Paty D,Graeb D

    更新日期:1994-06-01 00:00:00

  • Specific absorption rate intersubject variability in 7T parallel transmit MRI of the head.

    abstract::Patient-specific radiofrequency shimming in high-field MRI strengthens the need for online, patient-specific specific absorption rate (SAR) monitoring. Numerical simulation is currently most effective for this purpose but may require a patient-specific dielectric model. To investigate whether a generic model may be co...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24378

    authors: de Greef M,Ipek O,Raaijmakers AJ,Crezee J,van den Berg CA

    更新日期:2013-05-01 00:00:00

  • Inverse reconstruction method for segmented multishot diffusion-weighted MRI with multiple coils.

    abstract::Each k-space segment in multishot diffusion-weighted MRI is affected by a different spatially varying phase which is caused by unavoidable motions and amplified by the diffusion-encoding gradients. A proper image reconstruction therefore requires phase maps for each segment. Such maps are commonly derived from two-dim...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22126

    authors: Uecker M,Karaus A,Frahm J

    更新日期:2009-11-01 00:00:00

  • Eddy current correction in diffusion-weighted imaging using pairs of images acquired with opposite diffusion gradient polarity.

    abstract::In echo-planar-based diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI), the evaluation of diffusion parameters such as apparent diffusion coefficients and anisotropy indices is affected by image distortions that arise from residual eddy currents produced by the diffusion-sensitizing gradients. Correc...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10690

    authors: Bodammer N,Kaufmann J,Kanowski M,Tempelmann C

    更新日期:2004-01-01 00:00:00

  • NMR relaxometric investigation on human methemoglobin and fluoromethemoglobin. An improved quantitative in vitro assay of human methemoglobin.

    abstract::Longitudinal water proton relaxation rates of methemoglobin solutions show a strong dependence on temperature and pH. The increase of the relaxation rates with temperature is associated with shortened exchange lifetime of the coordinated water molecule. An accurate measurement of the relaxation rate of methemoglobin s...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910330613

    authors: Aime S,Fasano M,Paoletti S,Arnelli A,Ascenzi P

    更新日期:1995-06-01 00:00:00

  • Steady state of echo-shifted sequences with radiofrequency phase cycling.

    abstract::Due to a delayed echo-formation, echo-shifted gradient echo sequences (ES-GRE) allow for an enhanced T(2)*-weighting at short repetition times. While they are in use with and without RF spoiling, analytical solutions are only known for the latter. The signal formation in the former could only be assessed in approximat...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21010

    authors: Ganter C

    更新日期:2006-10-01 00:00:00

  • Quantitative brain relaxation atlases for personalized detection and characterization of brain pathology.

    abstract:PURPOSE:To exploit the improved comparability and hardware independency of quantitative MRI, databases of MR physical parameters in healthy tissue are required, to which tissue properties of patients can be compared. In this work, normative values for longitudinal and transverse relaxation times in the brain were estab...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27927

    authors: Piredda GF,Hilbert T,Granziera C,Bonnier G,Meuli R,Molinari F,Thiran JP,Kober T

    更新日期:2020-01-01 00:00:00

  • 31P RINEPT MRSI and VBM reveal alterations in brain aging associated with major depression.

    abstract:PURPOSE:Phosphomono- and diesters, the major components of the choline peak in (1) H magnetic resonance spectroscopy, are associated with membrane anabolic and catabolic mechanisms. With the refocused insensitive nuclei-enhanced polarization transfer technique, these phospholipids are edited and enhanced in the (31) P ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25278

    authors: Biedermann SV,Weber-Fahr W,Demirakca T,Tunc-Skarka N,Hoerst M,Henn F,Sartorius A,Ende G

    更新日期:2015-04-01 00:00:00

  • Combined geometric and algebraic solutions for removal of bSSFP banding artifacts with performance comparisons.

    abstract:PURPOSE:Balanced steady state free precession (bSSFP) imaging suffers from off-resonance artifacts such as signal modulation and banding. Solutions for removal of bSSFP off-resonance dependence are described and compared, and an optimal solution is proposed. THEORY AND METHODS:An Algebraic Solution (AS) that complemen...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26150

    authors: Hoff MN,Andre JB,Xiang QS

    更新日期:2017-02-01 00:00:00

  • Strategy for lipid suppression in lactate imaging using STIR-DQCT: a study of hypoxic-ischemic brain injury.

    abstract::In vivo lactate detection using gradient enhanced double quantum coherence transfer (DQCT) was significantly improved by addition of short-time-inversion-recovery (STIR). Phantom studies demonstrated lipid suppression down to the background noise level with 33% loss of lactate signal. In vivo studies using a rabbit mo...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910400416

    authors: Nakai T,Rhine WD,Okada T,Stevenson DK,Spielman DM

    更新日期:1998-10-01 00:00:00

  • Noise removal in magnetic resonance diffusion tensor imaging.

    abstract::Although promising for visualizing the structure of ordered tissues, MR diffusion tensor imaging (DTI) has been hampered by long acquisition time and low spatial resolution associated with its inherently low signal-to-noise ratio (SNR). Moreover, the uncertainty in the DTI measurements has a direct impact on the accur...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20582

    authors: Chen B,Hsu EW

    更新日期:2005-08-01 00:00:00

  • Cardiac tagging with breath-hold cine MRI.

    abstract::A method is presented for measuring myocardial deformation in a breath-hold with tagged cine MRI. Tagged cine images of human hearts are obtained in arbitrary oblique planes on a standard imager with as few as four heartbeats. The scan time has been reduced 16- to 64-fold from previous techniques. ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910280214

    authors: McVeigh ER,Atalar E

    更新日期:1992-12-01 00:00:00

  • Dynamic per slice shimming for simultaneous brain and spinal cord fMRI.

    abstract:PURPOSE:Simultaneous brain and spinal cord functional MRI is emerging as a new tool to study the central nervous system but is challenging. Poor B0 homogeneity and small size of the spinal cord are principal obstacles to this nascent technology. Here we extend a dynamic shimming approach, first posed by Finsterbusch, b...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27388

    authors: Islam H,Law CSW,Weber KA,Mackey SC,Glover GH

    更新日期:2019-02-01 00:00:00

  • Fast, three-dimensional free-breathing MR imaging of myocardial infarction: a feasibility study.

    abstract::Imaging delayed hyperenhancement of myocardial infarction is most commonly performed using an inversion recovery (IR) prepared 2D breathhold segmented k-space gradient echo (FGRE) sequence. Since only one slice is acquired per breathhold in this technique, 12-16 successive breathholds are required for complete anatomi...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20061

    authors: Saranathan M,Rochitte CE,Foo TK

    更新日期:2004-05-01 00:00:00

  • View-ordering in radial fast spin-echo imaging.

    abstract::Radial MRI sequences are frequently used to obtain images with reduced sensitivity to motion. To decrease imaging time, multiple spin-echo acquisitions can be incorporated into radial sequences. In this case, different radial lines of Fourier data have different TE times and the resulting images can contain streaking ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20031

    authors: Theilmann RJ,Gmitro AF,Altbach MI,Trouard TP

    更新日期:2004-04-01 00:00:00

  • Safety of gadolinium-DTPA: extended clinical experience.

    abstract::This review reports data on the general and renal tolerance of the paramagnetic contrast agent Gd-DTPA after intravenous administration. Gd-DTPA was administered usually at a dose level of 0.1-0.2 mmol/kg body wt (range: 0.005-0.25 mmol/kg body wt) in cranial, spinal and body MR indications. In phase I-IIIa studies a ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章,评审

    doi:10.1002/mrm.1910220212

    authors: Niendorf HP,Haustein J,Cornelius I,Alhassan A,Clauss W

    更新日期:1991-12-01 00:00:00

  • Gradient characterization using a Fourier-transform technique.

    abstract::This paper describes a technique for characterizing the gradient subsystem of a magnetic resonance (MR) system. The technique uses a Fourier-transform analysis to directly measure the k-space trajectory produced by an arbitrary gradient waveform. In addition, the method can be easily extended to multiple dimensions an...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910390411

    authors: Alley MT,Glover GH,Pelc NJ

    更新日期:1998-04-01 00:00:00