Abstract:
PURPOSE:To develop a three-dimensional, free-breathing, late gadolinium enhancement (3D FB-LGE) cardiovascular magnetic resonance (CMR) technique, and to compare it with clinically used two-dimensional breath-hold LGE (2D BH-LGE). METHODS:The proposed 3D FB-LGE method consisted of inversion preparation, inversion delay, fat saturation, outer volume suppression, one-dimensional projection navigators, and a segmented stack of spirals acquisition. The 3D FB-LGE and 2D BH-LGE scans were performed on 29 cardiac patients. Qualitative analysis and quantitative analysis (in patients with scar) were performed. RESULTS:No significant differences were noted between the 3D FB-LGE and 2D BH-LGE data sets in terms of overall image quality score (2D: 4.69 ± 0.60 versus 3D: 4.55 ± 0.51, P = 0.46) and image artifact score (2D: 1.10 ± 0.31 versus 3D: 1.17 ± 0.38; P = 0.63). The average difference in fractional scar volume between the 3D and 2D methods was 1.9% (n = 5). Acquisition time was significantly shorter for the 3D FB-LGE over 2D BH-LGE by a factor of 2.83 ± 0.77 (P < 0.0001). CONCLUSIONS:The 3D FB-LGE is a viable option for patients, particularly in acute settings or in patients who are unable to comply with breath-hold instructions. Magn Reson Med 77:1533-1543, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Menon RG,Miller GW,Jeudy J,Rajagopalan S,Shin Tdoi
10.1002/mrm.26234subject
Has Abstractpub_date
2017-04-01 00:00:00pages
1533-1543issue
4eissn
0740-3194issn
1522-2594journal_volume
77pub_type
杂志文章abstract:PURPOSE:Spiral readouts combine several favorable properties that promise superior net sensitivity for diffusion imaging. The purpose of this study is to verify the signal-to-noise ratio (SNR) benefit of spiral acquisition in comparison with current echo-planar imaging (EPI) schemes. METHODS:Diffusion-weighted in vivo...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.28554
更新日期:2021-04-01 00:00:00
abstract::Three-dimensional magnetization-prepared (MP) MR angiography (MRA) was applied to the carotid and vertebral arteries by using ECG triggering, a slab selective RF inversion pulse, centric phase encoding and acquisition during diastole. Both theoretically and experimentally, the MP MRA sequence was shown to perform well...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910370219
更新日期:1997-02-01 00:00:00
abstract:PURPOSE:MR-based quantification of liver magnetic susceptibility may enable field strength-independent measurement of liver iron concentration (LIC). However, susceptibility quantification is challenging, due to nonlocal effects of susceptibility on the B0 field. The purpose of this work is to demonstrate feasibility o...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24848
更新日期:2013-09-01 00:00:00
abstract::The purpose of this study is to examine the usefulness of histogram analysis combined with vessel size index (VSI) magnetic resonance imaging for the specific characterization of brain tumor microvasculature in a panel of six volume-matched glioma xenografts. Using a simple descriptive histogram analysis, significant ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22675
更新日期:2011-03-01 00:00:00
abstract::Optimization of experimental settings of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), like the contrast administration protocol, is of great importance for reliable quantification of the microcirculatory properties, such as the volume transfer-constant K(trans). Using system identification theory an...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21575
更新日期:2008-05-01 00:00:00
abstract:PURPOSE:A method for the quantification of perfusion in murine myocardium is demonstrated. The method allows for the reconstruction of perfusion maps on arbitrary time points in the heart cycle while addressing problems that arise due to the irregular heart beat of mice. METHODS:A flow-sensitive alternating inversion ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25526
更新日期:2015-12-01 00:00:00
abstract::A receive-only phased-array coil was designed to image the lower extremities. The array consists of four volume coils placed on two cylindrical formers. The coil array has the ability to image both legs simultaneously over a 40 cm longitudinal field of view (FOV). Experiments using phantoms show an increase in signal-...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10712
更新日期:2004-03-01 00:00:00
abstract:PURPOSE:Oscillating gradient spin-echo (OGSE) diffusion MRI provides information about the microstructure of biological tissues by means of the frequency dependence of the apparent diffusion coefficient (ADC). ADC dependence on OGSE frequency has been explored in numerous rodent studies, but applications in the human b...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.28083
更新日期:2020-06-01 00:00:00
abstract::The ability to generate in vivo maps of lactate may have significant diagnostic utility in staging and treatment planning of a wide variety of cancers. The double selective multiple quantum filter technique (SelMQC) has been shown to be effective for nonlocalized detection of lactate with little or no interference fro...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21659
更新日期:2008-08-01 00:00:00
abstract::We have noninvasively produced low-resolution, quantitative nuclear magnetic resonance images of cerebral blood flow in 2-ml voxels in eight cats. Typical signal-to-noise of 4 to 1 was obtained in cerebral voxels in 16.5-s epochs. Mean flow during normocapnia (paCO2 = 39 +/- 4 mm Hg) and hypercapnia (paCO2 = 62 +/- 4 ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910280105
更新日期:1992-11-01 00:00:00
abstract:PURPOSE:To present a double diffusion encoding MRI sequence on a clinical scanner to analyze micro-structure and micro-vasculature of tumors. METHODS:The sequence was tested on phantoms, asparaguses, and 2 tumors allografts in a rodent. Results were analyzed using an adapted VERDICT model to estimate microstructural p...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.28012
更新日期:2020-04-01 00:00:00
abstract::The estrogen receptor (ER) is a major prognostic biomarker of breast cancer, currently determined in surgical specimens by immunohistochemistry. Two new ER-targeted probes, pyridine-tetra-acetate-Gd chelate (PTA-Gd) conjugated either to 17β-estradiol (EPTA-Gd) or to tamoxifen (TPTA-Gd), were explored as contrast agent...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.24442
更新日期:2013-07-01 00:00:00
abstract::Quantification of peak velocity is important in the assessment of stenotic flow jets in patients with congenital heart disease. Phase-contrast magnetic resonance underestimates peak velocities. Hence, clinically Doppler ultrasound is used as the reference standard for assessing stenoses. It is possible to accurately m...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24293
更新日期:2012-06-01 00:00:00
abstract::Proton-electron double-resonance imaging (PEDRI) was used to assess renal function by monitoring the flow of the exogenous nitroxide free radical proxyl carboxylic acid (PCA) through normal and injured kidneys in the living rat. Kidney damage was induced by treatment with 2-bromoethylamine (BEA), which provides a well...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910400214
更新日期:1998-08-01 00:00:00
abstract::The authors addressed the hypothesis that interactions with creatine kinase (CK) play a role in the off-resonance magnetization transfer (MT) effect of creatine in skeletal muscle. Toward that aim, (1)H MT studies were done on hindleg muscle in wild-type mice and in transgenic mice, lacking cytoplasmic CK and/or mitoc...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/(sici)1522-2594(200005)43:5<657::aid-mrm7>
更新日期:2000-05-01 00:00:00
abstract::The reconstruction of MR images from nonrectilinearly sampled data is complicated by the fact that the inverse 2D Fourier transform (FT) cannot be performed directly on the acquired k-space data set. k-Space gridding is commonly used because it is an efficient reconstruction method. However, conventional gridding requ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10692
更新日期:2004-02-01 00:00:00
abstract::Functional magnetic resonance imaging in real time is an emerging tool for the assessment of dynamic changes in brain activation. The short response latency (tens of seconds) renders the technique more sensitive to motion artifacts. Motion correction in real time requires computationally efficient algorithms which can...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/1522-2594(200101)45:1<167::aid-mrm1023>3.0
更新日期:2001-01-01 00:00:00
abstract::The time evolution of water diffusion, perfusion, T1, and T2 is investigated at high magnetic field (8.5 T) following permanent middle cerebral artery occlusion in the rat. Cerebral blood flow maps were obtained using arterial spin tagging. Although the quantitative perfusion measurements in ischemic tissue still pose...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/(sici)1522-2594(199903)41:3<479::aid-mrm9>
更新日期:1999-03-01 00:00:00
abstract::The somatotopical organization of the human somatosensory cortex was analyzed with echo-planar imaging at 1.5 Tesla, utilizing deoxyhemoglobin as an endogenous contrast medium. Scrubbing stimulation at a frequency of 3 Hz was applied to one of three cutaneous areas: toes, fingertips, and tongue tip. Parasagittal echo-...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
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更新日期:1995-05-01 00:00:00
abstract::MRI after a constant infusion (CI) of Gd-DTPA has been used to identify the extent of myocardial infarction (MI). However, Gd-DTPA-enhanced "viability" imaging is more commonly performed with a bolus (for "delayed-enhancement" (DE) imaging). This study sought to determine how image delay time and time postinfarction i...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.20236
更新日期:2004-11-01 00:00:00
abstract::The accuracy of perfusion measurements using dynamic, susceptibility-weighted, contrast-enhanced MRI depends on estimating contrast agent concentration in an artery, i.e., the arterial input function. One of the difficulties associated with obtaining an arterial input function are partial volume effects when both bloo...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.24331
更新日期:2013-04-01 00:00:00
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journal_title:Magnetic resonance in medicine
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更新日期:2014-08-01 00:00:00
abstract:PURPOSE:To investigate Shift Undersampling improves Parametric mapping Efficiency and Resolution (SUPER), a novel blockwise curve-fitting method for accelerating parametric mapping with very fast reconstruction. METHODS:SUPER uses interleaved k-space undersampling, which enables a blockwise decomposition of the otherw...
journal_title:Magnetic resonance in medicine
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更新日期:2019-06-01 00:00:00
abstract::A novel method for reducing the rf power requirements of selective pulses employed for z magnetization slice inversion in localized NMR spectroscopy is presented. Following slice preparation by the use of frequency-incremented sinc pulses, the slice gradient is reduced, which narrows the frequency width of the slice. ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910050610
更新日期:1987-12-01 00:00:00
abstract::Due to a delayed echo-formation, echo-shifted gradient echo sequences (ES-GRE) allow for an enhanced T(2)*-weighting at short repetition times. While they are in use with and without RF spoiling, analytical solutions are only known for the latter. The signal formation in the former could only be assessed in approximat...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21010
更新日期:2006-10-01 00:00:00
abstract::Brain water proton (1H2O) longitudinal relaxation time constants (T1) were obtained from three healthy individuals at magnetic field strengths (B0) of 0.2 Tesla (T), 1.0T, 1.5T, 4.0T, and 7.0T. A 5-mm midventricular axial slice was sampled using a modified Look-Locker technique with 1.5 mm in-plane resolution, and 32 ...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.21122
更新日期:2007-02-01 00:00:00
abstract::The presence of macroscopic vessels within the tumor region is a potential confounding factor in MR-based dynamic susceptibility contrast (DSC)-enhanced glioma grading. In order to distinguish between such vessels and the elevated cerebral blood volume (CBV) of brain tumors, we propose a vessel segmentation technique ...
journal_title:Magnetic resonance in medicine
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更新日期:2009-05-01 00:00:00
abstract::The diffusional kurtosis is an indicator for diffusion restrictions in biological tissue. It is observed experimentally that the kurtosis is largest for directions perpendicular to the fiber direction in white matter. The directional dependence of the kurtosis can be described by the diffusion kurtosis tensor. Since t...
journal_title:Magnetic resonance in medicine
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更新日期:2012-05-01 00:00:00
abstract::Parallel transmission has emerged as an efficient means for implementing multidimensional spatially selective radiofrequency excitation pulses. To date, most theoretical and experimental work on parallel transmission radiofrequency (RF) pulse design is based on the small-tip-angle approximation to the Bloch equation. ...
journal_title:Magnetic resonance in medicine
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更新日期:2011-09-01 00:00:00
abstract::In a research environment, a magnetic resonance imaging system's manufacturer-supplied protection against excessive rf power deposition in the sample is often compromised. This paper presents a widely applicable scheme, based on a commonly available fuse, that simply and effectively limits the average rf power into a ...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.1910090213
更新日期:1989-02-01 00:00:00