Abstract:
:We have noninvasively produced low-resolution, quantitative nuclear magnetic resonance images of cerebral blood flow in 2-ml voxels in eight cats. Typical signal-to-noise of 4 to 1 was obtained in cerebral voxels in 16.5-s epochs. Mean flow during normocapnia (paCO2 = 39 +/- 4 mm Hg) and hypercapnia (paCO2 = 62 +/- 4 mm Hg) was 53 +/- 20 ml/100 g-min and 140 +/- 36 ml/100 g-min, respectively. Fast flows in normocapnia were 94 +/- 13 and 182 +/- 39 ml/100 g-min in hypercapnia. These results suggest that an atraumatic quantitative imaging assessment of cerebral perfusion may be possible in humans using these techniques.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Branch CA,Ewing JR,Helpern JA,Ordidge RJ,Butt S,Welch KMdoi
10.1002/mrm.1910280105subject
Has Abstractpub_date
1992-11-01 00:00:00pages
39-53issue
1eissn
0740-3194issn
1522-2594journal_volume
28pub_type
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journal_title:Magnetic resonance in medicine
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