Feasibility of multiple-mouse dynamic contrast-enhanced MRI.

abstract：:In rapidly acquired gradient echo images, lipid regions usually appear as areas of high signal intensity. In 2D inflow angiograms processed by the maximum intensity projection algorithm, this high lipid signal may prevent angiographic visualization of some blood vessels. We present a new approach to suppress the lipid...

journal_title：Magnetic resonance in medicine

authors： Doyle M,Matsuda T,Pohost GM

更新日期：1991-09-01 00:00:00

abstract：PURPOSE:To reduce the influence of tidal volume on fractional ventilation (FV) derived by Fourier decomposition (FD). METHODS:Twelve volunteers were examined on a 1.5 Tesla scanner. Spoiled gradient echo imaging of coronal and sagittal slices of the lung were performed. The tidal volume variations between different ac...

journal_title：Magnetic resonance in medicine

authors： Voskrebenzev A,Gutberlet M,Becker L,Wacker F,Vogel-Claussen J

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:We sought to develop and test a clinically feasible 1-point Dixon, three-dimensional (3D) radial acquisition strategy to create isotropic 3D MR images of (129)Xe in the airspaces, barrier, and red blood cells (RBCs) in a single breath. The approach was evaluated in healthy volunteers and subjects with idiopathi...

journal_title：Magnetic resonance in medicine

authors： Kaushik SS,Robertson SH,Freeman MS,He M,Kelly KT,Roos JE,Rackley CR,Foster WM,McAdams HP,Driehuys B

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:Endothelial nitric oxide synthase (eNOS) plays a central role in regulating vascular tone, blood flow, and microvascular permeability. Endothelial dysfunction, including eNOS dysfunction, is an early biomarker of vascular disease. This study aimed to show that myocardial T1 mapping during nitric oxide synthase ...

journal_title：Magnetic resonance in medicine

authors： Cui SX,Epstein FH

更新日期：2018-04-01 00:00:00

abstract：:In proton magnetic resonance imaging (MRI) metallic substances lead to magnetic field distortions that often result in signal voids in the adjacent anatomic structures. Thus, metallic objects and superparamagnetic iron oxide (SPIO)-labeled cells appear as hypointense artifacts that obscure the underlying anatomy. The ...

journal_title：Magnetic resonance in medicine

authors： Stuber M,Gilson WD,Schär M,Kedziorek DA,Hofmann LV,Shah S,Vonken EJ,Bulte JW,Kraitchman DL

更新日期：2007-11-01 00:00:00

abstract：PURPOSE:To develop a method for acquiring whole-heart 3D image-based navigators (iNAVs) with isotropic resolution for tracking and correction of localized motion in coronary magnetic resonance angiography (CMRA). METHODS:To monitor motion in all regions of the heart during a free-breathing scan, a variable-density con...

journal_title：Magnetic resonance in medicine

authors： Addy NO,Ingle RR,Luo J,Baron CA,Yang PC,Hu BS,Nishimura DG

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:Respiratory motion makes hepatic ablation using high intensity focused ultrasound (HIFO) challenging. Previous HIFU liver treatment had required apnea induced during general anesthesia. We describe and test a system that allows treatment of the liver in the presence of breathing motion. METHODS:Mapping a signa...

journal_title：Magnetic resonance in medicine

authors： Holbrook AB,Ghanouni P,Santos JM,Dumoulin C,Medan Y,Pauly KB

更新日期：2014-02-01 00:00:00

abstract：:Given its greater availability and lower cost, (129) Xe apparent diffusion coefficient (ADC) MRI offers an alternative to (3) He ADC MRI. To demonstrate the feasibility of hyperpolarized (129) Xe ADC MRI, we present results from healthy volunteers (HV), chronic obstructive pulmonary disease (COPD) subjects, and age-ma...

journal_title：Magnetic resonance in medicine

authors： Kaushik SS,Cleveland ZI,Cofer GP,Metz G,Beaver D,Nouls J,Kraft M,Auffermann W,Wolber J,McAdams HP,Driehuys B

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:We propose a constrained optimization approach for designing parallel transmit (pTx) pulses satisfying all regulatory and hardware limits. We study the trade-offs between excitation accuracy, local and global specific absorption rate (SAR), and maximum and average power for small flip-angle pTx (eight channels)...

journal_title：Magnetic resonance in medicine

authors： Guérin B,Gebhardt M,Cauley S,Adalsteinsson E,Wald LL

更新日期：2014-04-01 00:00:00

abstract：:The previously observed improvement in spectral resolution of tissue proton NMR with high-resolution magic angle spinning (HRMAS) was speculated to be due largely to freeze-thawing artifacts resulting from tissue storage. In this study, 12 human prostate samples were analyzed on a 14.1T spectrometer at 3 degrees C, wi...

journal_title：Magnetic resonance in medicine

authors： Wu CL,Taylor JL,He W,Zepeda AG,Halpern EF,Bielecki A,Gonzalez RG,Cheng LL

更新日期：2003-12-01 00:00:00

abstract：:Hydrogen, sodium, and fluorine (added F-) NMR spectra of venous and oxygenated blood were measured. The fluorine resonance was seen as a single peak in both samples, and all three resonances exhibited the same deoxy-oxy shift. Because F- exchanges slowly across the red cell membrane, and because sodium is 95% extracel...

journal_title：Magnetic resonance in medicine

authors： Brooks RA,Brunetti A,Alger JR,Di Chiro G

更新日期：1989-11-01 00:00:00

abstract：:A stereotaxic restraining assembly was designed and developed for simultaneous electrophysiological recordings and functional MRI (fMRI) data acquisition from a conscious rat. The design of the nonmagnetic stereotaxic apparatus facilitated the restraining of head and body of the unanesthetized conscious animal during ...

journal_title：Magnetic resonance in medicine

authors： Khubchandani M,Mallick HN,Jagannathan NR,Mohan Kumar V

更新日期：2003-05-01 00:00:00

abstract：:Perfusion imaging by arterial spin labeling (ASL) can be highly sensitive to the transit time from the labeling site to the tissue. We report the results of a study designed to separate the transit time and perfusion contributions to activation in ASL images accompanying motor and visual stimulation. Fractional transi...

journal_title：Magnetic resonance in medicine

authors： Gonzalez-At JB,Alsop DC,Detre JA

更新日期：2000-05-01 00:00:00

abstract：:Dynamic imaging strategies often involve updating certain areas of k-space (i.e., the low spatial frequencies) more frequently than others. However, important dynamic signal changes may occur anywhere in k-space. In this study, a dynamic k-space sampling analysis method was developed to determine the energy error asso...

journal_title：Magnetic resonance in medicine

authors： Wu Y,Alexander AL

更新日期：2001-04-01 00:00:00

abstract：:Chemical exchange saturation transfer (CEST), arterial spin labeling (ASL), and magnetization transfer contrast (MTC) methods generate different contrasts for MRI. However, they share many similarities in terms of pulse sequences and mechanistic principles. They all use RF pulse preparation schemes to label the longit...

journal_title：Magnetic resonance in medicine

authors： Knutsson L,Xu J,Ahlgren A,van Zijl PCM

更新日期：2018-10-01 00:00:00

abstract：:It is shown that the effect of pH changes can be measured in proton NMR spectra through the pH sensitivity of the signal intensities of metabolite protons exchanging with water. To observe this phenomenon, pulse sequences must be used that can sensitively observe these exchangeable protons under physiological conditio...

journal_title：Magnetic resonance in medicine

authors： Mori S,Eleff SM,Pilatus U,Mori N,van Zijl PC

更新日期：1998-07-01 00:00:00

abstract：PURPOSE:The clinical potential of the diffusion imaging-based analysis of fine brain structures such as fornix or cingulum is high due to the central role of these structures in psychiatric diseases. However, the quantification of diffusion parameters in fine structures is especially prone to partial volume effects (PV...

journal_title：Magnetic resonance in medicine

authors： Bach M,Fritzsche KH,Stieltjes B,Laun FB

更新日期：2014-03-01 00:00:00

abstract：:The relative distributions of N-acetylaspartate (NAA) + N-acetylaspartylglutamate (NAAG), creatine + phosphocreatine (Cr/PCr), and choline (Cho) in the gray and white matter of human brain were determined by utilizing proton magnetic resonance spectroscopic imaging (SI). The SI data was processed using an automated sp...

journal_title：Magnetic resonance in medicine

authors： Doyle TJ,Bedell BJ,Narayana PA

更新日期：1995-06-01 00:00:00

abstract：:Chemical shift imaging benefits from signal-to-noise ratio (SNR) and chemical shift dispersion increases at stronger main field such as 7 Tesla, but the associated shorter radiofrequency (RF) wavelengths encountered require B1+ mitigation over both the spatial field of view (FOV) and a specified spectral bandwidth. Th...

journal_title：Magnetic resonance in medicine

authors： Setsompop K,Alagappan V,Gagoski BA,Potthast A,Hebrank F,Fontius U,Schmitt F,Wald LL,Adalsteinsson E

更新日期：2009-02-01 00:00:00

abstract：:Prepolarized MRI uses pulsed magnetic fields to produce MR images by polarizing the sample at one field strength (approximately 0.5 T) before imaging at a much lower field (approximately 50 mT). Contrast reflecting the T(1) of the sample at an intermediate field strength is achieved by polarizing the sample and then a...

journal_title：Magnetic resonance in medicine

authors： Ungersma SE,Matter NI,Hardy JW,Venook RD,Macovski A,Conolly SM,Scott GC

更新日期：2006-06-01 00:00:00

abstract：:A multifocal mouse liver tumor model chemically induced with 5,9-dimethyl-7H-dibenzo[c,g]carbazole was investigated by respiratory-triggered morphological and functional MRI (fMRI) at 4.7 Tesla. The model is characterized by the presence of two tumor types: hypovascular cholangioma and vascularized hepatocellular carc...

journal_title：Magnetic resonance in medicine

authors： Thomas CD,Chenu E,Walczak C,Plessis MJ,Perin F,Volk A

更新日期：2003-09-01 00:00:00

abstract：:In vivo echo-planar MR imaging was used to measure apparent diffusion coefficients (ADC) of cerebral tissues in a comprehensive noninvasive evaluation of early ischemic brain damage induced by occlusion of the middle cerebral artery (MCA) in a cat model of acute regional stroke. Within 10 min after arterial occlusion,...

journal_title：Magnetic resonance in medicine

authors： Kucharczyk J,Mintorovitch J,Asgari HS,Moseley M

更新日期：1991-06-01 00:00:00

abstract：PURPOSE:To improve quantification of myocardial blood flow using a fast T1 mapping technique using highly constrained back projection reconstruction (HYPR)-accelerated acquisition. METHODS:A major source of error in the measurement of myocardial blood flow (MBF) using MRI is the nonlinear relationship between image si...

journal_title：Magnetic resonance in medicine

authors： Chen D,Sharif B,Dharmakumar R,Thomson LE,Bairey Merz CN,Berman DS,Li D

更新日期：2014-09-01 00:00:00

abstract：:MnCl(2) was injected intrathecally through the cisterna magna in rats, allowing infusion of divalent manganese ions (Mn(++)) into the CSF space and thence into the brain, without breaking the blood-brain barrier (BBB). Mn(++) uptake and washout dynamics in the brain were measured by serial T(1)-weighted MRI and EPI T(...

journal_title：Magnetic resonance in medicine

authors： Liu CH,D'Arceuil HE,de Crespigny AJ

更新日期：2004-05-01 00:00:00

abstract：PURPOSE:To develop and evaluate a novel two-dimensional self-gated imaging technique for free-breathing cardiac cine MRI that is free of motion-detection overhead and requires minimal planning for motion tracking. METHODS:Motion along the readout direction was extracted solely from normal Cartesian imaging readouts ne...

journal_title：Magnetic resonance in medicine

authors： Guo L,Derbyshire JA,Herzka DA

更新日期：2016-08-01 00:00:00

abstract：:The preovulatory rat follicle reaches a diameter of 1 mm with no internal blood vessels. Nutrient supply to the enclosed oocyte depends solely on passive diffusion across the follicular wall and the follicular fluid. Spin-echo and stimulated-echo NMR microscopy experiments were applied here for studying modulations in...

journal_title：Magnetic resonance in medicine

authors： Tempel C,Schiffenbauer YS,Meir G,Neeman M

更新日期：1995-08-01 00:00:00

abstract：PURPOSE:The optic nerve (ON) represents the sole pathway between the eyes and brain; consequently, diseases of the ON can have dramatic effects on vision. However, quantitative magnetization transfer (qMT) applications in the ON have been limited to ex vivo studies, in part because of the fatty connective tissue that s...

journal_title：Magnetic resonance in medicine

authors： Smith AK,Dortch RD,Dethrage LM,Lyttle BD,Kang H,Welch EB,Smith SA

更新日期：2017-02-01 00:00:00

abstract：:Unusually high image contrast in vivo magnetic resonance imaging of the brain becomes observable at high magnetic fields when the blood oxygenation level is lowered. The cause of the contrast has been attributed to a magnetic susceptibility effect induced by paramagnetic deoxyhemoglobin in red cells. When the cylinder...

journal_title：Magnetic resonance in medicine

authors： Ogawa S,Lee TM

更新日期：1990-10-01 00:00:00

abstract：:The combination of an in-plane B(1) sensitivity encoding (SENSE) technique with a simultaneous multiple-slice B(0) field step technique (multiple-acquisition micro B(0) array (MAMBA)) has produced high scan time reduction factors (R < or = 8). In this study, two slices were acquired simultaneously in combination with ...

journal_title：Magnetic resonance in medicine

authors： Paley MN,Lee KJ,Wild JM,Fichele S,Whitby EH,Wilkinson ID,Van Beek EJ,Griffiths PD

更新日期：2003-06-01 00:00:00

abstract：PURPOSE:Quantitative mapping of the native T1 of the heart using the modified look-locker inversion recovery (MOLLI) technique provides high quality diagnostic information without requiring contrast agents. Previous work has considered the effects of T2 relaxation on MOLLI T1 measurements, finding that the T1 measured ...

journal_title：Magnetic resonance in medicine

authors： Robson MD,Piechnik SK,Tunnicliffe EM,Neubauer S

更新日期：2013-09-01 00:00:00