Cerebral perfusion and arterial transit time changes during task activation determined with continuous arterial spin labeling.

Abstract:

:Perfusion imaging by arterial spin labeling (ASL) can be highly sensitive to the transit time from the labeling site to the tissue. We report the results of a study designed to separate the transit time and perfusion contributions to activation in ASL images accompanying motor and visual stimulation. Fractional transit time decreases were found to be comparable to fractional perfusion increases and the transit time change was found to be the greatest contributor to ASL signal change in ASL sequences without delayed acquisition. The implications for activation imaging with ASL and the arterial control of flow are discussed.

journal_name

Magn Reson Med

authors

Gonzalez-At JB,Alsop DC,Detre JA

doi

10.1002/(sici)1522-2594(200005)43:5<739::aid-mrm17

subject

Has Abstract

pub_date

2000-05-01 00:00:00

pages

739-46

issue

5

eissn

0740-3194

issn

1522-2594

pii

10.1002/(SICI)1522-2594(200005)43:5<739::AID-MRM17

journal_volume

43

pub_type

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