Utilization of an intra-oral diamagnetic passive shim in functional MRI of the inferior frontal cortex.

Abstract:

:Due to the presence of gross magnetic susceptibility artifacts, functional MRI (fMRI) has proved problematic in studies of the human inferior frontal cortex (IFC). There is a strong desire, therefore, to employ techniques that mitigate susceptibility artifacts in the IFC while preserving the imaging parameters of an fMRI study. It has been shown that the use of a single, strongly diamagnetic, intra-oral passive shim significantly improves the homogeneity of the static magnetic field (B(0)) and, as a result, alleviates the susceptibility artifacts within the IFC. In this study, practical issues regarding the use of an intra-oral passive shim are examined. We investigated B(0) instabilities within the IFC resulting from subject head motion in order to calculate the effects of an intra-oral passive shim on the temporal variance of an EPI time series. These studies show that the addition of an intra-oral passive shim improves both B(0) homogeneity and signal stability, and increases sensitivity to functional activation.

journal_name

Magn Reson Med

authors

Wilson JL,Jezzard P

doi

10.1002/mrm.10626

subject

Has Abstract

pub_date

2003-11-01 00:00:00

pages

1089-94

issue

5

eissn

0740-3194

issn

1522-2594

journal_volume

50

pub_type

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