Relative concentrations of proton MR visible neurochemicals in gray and white matter in human brain.

Abstract:

:The relative distributions of N-acetylaspartate (NAA) + N-acetylaspartylglutamate (NAAG), creatine + phosphocreatine (Cr/PCr), and choline (Cho) in the gray and white matter of human brain were determined by utilizing proton magnetic resonance spectroscopic imaging (SI). The SI data was processed using an automated spectroscopic image processing algorithm, and image segmentation was performed using a supervised technique. Linear regression analysis indicated that the NAA + NAAG (2.01 ppm) and Cr/PCr (3.02 ppm) peaks are greater in gray matter compared with white matter. The large intersubject variation observed in the Cho (3.20 ppm) resonance prevented the assessment of its regional distribution with confidence.

journal_name

Magn Reson Med

authors

Doyle TJ,Bedell BJ,Narayana PA

doi

10.1002/mrm.1910330603

subject

Has Abstract

pub_date

1995-06-01 00:00:00

pages

755-9

issue

6

eissn

0740-3194

issn

1522-2594

journal_volume

33

pub_type

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