Improved large tip angle parallel transmission pulse design through a perturbation analysis of the Bloch equation.

abstract：PURPOSE:The correlation between glutamine metabolism and oncogene expression in cancers has led to a renewed interest in the role of glutamine in cancer cell survival. Hyperpolarized [5-(13) C]glutamine is evaluated as a potential biomarker for noninvasive metabolic measurements of drug response in prostate cancer cell...

journal_title：Magnetic resonance in medicine

authors： Canapè C,Catanzaro G,Terreno E,Karlsson M,Lerche MH,Jensen PR

更新日期：2015-06-01 00:00:00

abstract：:The effects of macroscopic background field gradients upon 2D gradient echo images of inhaled (3)He in the human lung were investigated at 1.5 T. Effective compensation of in-slice signal loss in (3)He gradient echo images was then demonstrated using a multiple acquisition interleaved single gradient echo sequence. Th...

journal_title：Magnetic resonance in medicine

authors： Wild JM,Fichele S,Woodhouse N,Paley MN,Swift A,Kasuboski L,van Beek EJ

更新日期：2003-08-01 00:00:00

abstract：PURPOSE:Atherosclerotic carotid plaques can be quantified in vivo by MRI. However, the accuracy in segmentation and quantification of components such as the thin fibrous cap (FC) and lipid-rich necrotic core (LRNC) remains unknown due to the lack of a submillimeter scale ground truth. METHODS:A novel approach was take...

journal_title：Magnetic resonance in medicine

authors： Nieuwstadt HA,Geraedts TR,Truijman MT,Kooi ME,van der Lugt A,van der Steen AF,Wentzel JJ,Breeuwer M,Gijsen FJ

更新日期：2014-07-01 00:00:00

abstract：:Radiofrequency induced pacemaker lead tip heating is one of the main reasons magnetic resonance imaging (MRI) is contraindicated for patients with pacemakers. The objective of this work was to evaluate the dependence of pacemaker lead tip heating during MRI scanning on the electrical conductivity of the medium surroun...

journal_title：Magnetic resonance in medicine

authors： Langman DA,Goldberg IB,Judy J,Paul Finn J,Ennis DB

更新日期：2012-08-01 00:00:00

abstract：:Applications of fMRI in functional brain imaging are mainly confined to single subject designs, prohibiting the assessment of subject or group by condition interactions (i.e., differential activations) or areas of conjoint activation. In this paper a framework for fMRI group designs, using statistical parametric mappi...

journal_title：Magnetic resonance in medicine

authors： Büchel C,Turner R,Friston K

更新日期：1997-11-01 00:00:00

abstract：PURPOSE:The diseased myocardium lacks metabolic flexibility and responds to stimuli differently compared with healthy hearts. Here, we report the use of hyperpolarized 13C NMR spectroscopy to detect sudden changes in cardiac metabolism in isolated, perfused rat hearts in response to adrenergic stimulation. METHODS:Met...

journal_title：Magnetic resonance in medicine

authors： Khemtong C,Carpenter NR,Lumata LL,Merritt ME,Moreno KX,Kovacs Z,Malloy CR,Sherry AD

更新日期：2015-08-01 00:00:00

abstract：:In proton magnetic resonance imaging (MRI) metallic substances lead to magnetic field distortions that often result in signal voids in the adjacent anatomic structures. Thus, metallic objects and superparamagnetic iron oxide (SPIO)-labeled cells appear as hypointense artifacts that obscure the underlying anatomy. The ...

journal_title：Magnetic resonance in medicine

authors： Stuber M,Gilson WD,Schär M,Kedziorek DA,Hofmann LV,Shah S,Vonken EJ,Bulte JW,Kraitchman DL

更新日期：2007-11-01 00:00:00

abstract：:An improved double quantum coherence (DQC) filter for the selective in vivo detection of glutathione (GSH) in the human brain at 1.5 Tesla is presented. The goal was to minimize contamination of the DQC-filtered GSH signal at 2.9 ppm with contributions arising from GABA. The modification consists of tailoring the freq...

journal_title：Magnetic resonance in medicine

authors： Trabesinger AH,Boesiger P

更新日期：2001-04-01 00:00:00

abstract：PURPOSE:The purpose of this study was to develop a three-dimensional black blood imaging method for simultaneously evaluating the carotid and intracranial arterial vessel walls with high spatial resolution and excellent blood suppression with and without contrast enhancement. METHODS:The delay alternating with nutatio...

journal_title：Magnetic resonance in medicine

authors： Xie Y,Yang Q,Xie G,Pang J,Fan Z,Li D

更新日期：2016-06-01 00:00:00

abstract：:Multiple images acquired simultaneously from an array of surface coils can be combined to give a composite image with an improved signal-to-noise ratio (SNR) and a large field of view. The composite images' SNR can be optimized by taking advantage of noise correlations between coils and phase shifts induced by surface...

journal_title：Magnetic resonance in medicine

authors： Hayes CE,Roemer PB

更新日期：1990-11-01 00:00:00

abstract：PURPOSE:To compare fitting methods and sampling strategies, including the implementation of an optimized b-value selection for improved estimation of intravoxel incoherent motion (IVIM) parameters in breast cancer. METHODS:Fourteen patients (age, 48.4 ± 14.27 years) with cancerous lesions underwent 3 Tesla breast MRI ...

journal_title：Magnetic resonance in medicine

authors： Cho GY,Moy L,Zhang JL,Baete S,Lattanzi R,Moccaldi M,Babb JS,Kim S,Sodickson DK,Sigmund EE

更新日期：2015-10-01 00:00:00

abstract：:Image contrast with gradient-recalled echo sequences (GRE) used for fMRI can have both blood oxygen level-dependent (BOLD) and inflow components, and the latter is often undesirable. A dual-echo technique can be used to differentiate these mechanisms, because modulation of signal from inflow is common to both echoes, ...

journal_title：Magnetic resonance in medicine

authors： Glover GH,Lemieux SK,Drangova M,Pauly JM

更新日期：1996-03-01 00:00:00

abstract：:Levo-tetrahydropalmatine (l-THP) has shown significant promise in preclinical and clinical studies to treat drug addiction. Pharmacological MRI methods can elucidate the regional cerebral effects of l-THP, but there are potential confounds from the use of general anesthesia. To investigate the possible anesthetic-drug...

journal_title：Magnetic resonance in medicine

authors： Liu X,Li R,Yang Z,Hudetz AG,Li SJ

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:Amide-proton transfer (APT) and amine-water proton exchange (APEX) MRI can be viable to map pH-decreasing ischemic regions. However, their exact contributions are unclear. METHODS:We measured APEX- and APT-weighted magnetization transfer ratio asymmetry (denoted as APEXw and APTw), apparent diffusion coefficie...

journal_title：Magnetic resonance in medicine

authors： Zong X,Wang P,Kim SG,Jin T

更新日期：2014-01-01 00:00:00

abstract：:It is shown that the effect of pH changes can be measured in proton NMR spectra through the pH sensitivity of the signal intensities of metabolite protons exchanging with water. To observe this phenomenon, pulse sequences must be used that can sensitively observe these exchangeable protons under physiological conditio...

journal_title：Magnetic resonance in medicine

authors： Mori S,Eleff SM,Pilatus U,Mori N,van Zijl PC

更新日期：1998-07-01 00:00:00

abstract：:An eight-channel receive-only brain coil and table-top detunable volume transmit coil were developed and tested at 7 T for human imaging. Optimization of this device required attention to sources of interaction between the array elements, between the transmit and receive coils and minimization of common mode currents ...

journal_title：Magnetic resonance in medicine

authors： Wiggins GC,Potthast A,Triantafyllou C,Wiggins CJ,Wald LL

更新日期：2005-07-01 00:00:00

abstract：PURPOSE:To develop and validate a method for acquiring helium-3 ((3) He) and proton ((1) H) three-dimensional (3D) image sets of the human lung with isotropic spatial resolution within a 10-s breath-hold by using compressed sensing (CS) acceleration, and to assess the fidelity of undersampled images compared with fully...

journal_title：Magnetic resonance in medicine

authors： Qing K,Altes TA,Tustison NJ,Feng X,Chen X,Mata JF,Miller GW,de Lange EE,Tobias WA,Cates GD Jr,Brookeman JR,Mugler JP 3rd

更新日期：2015-10-01 00:00:00

abstract：:Phased-array coils distribute the high signal-to-noise ratio (SNR) performance of their small component surface coils over the larger area covered by the entire array. The inhomogeneous sensitivity profiles of the component surface coils result in images with very high signal near the phased-array and decreased signal...

journal_title：Magnetic resonance in medicine

authors： Murakami JW,Hayes CE,Weinberger E

更新日期：1996-04-01 00:00:00

abstract：:A novel ultra-rapid gradient echo (URGE) NMR imaging technique is introduced, which is capable of continuous high resolution 3D scanning while neither subject to fast gradient switching nor excessive RF power deposition. Sampling free induction decays instead of creating spin echoes enables maintaining a workable stea...

journal_title：Magnetic resonance in medicine

authors： Heid O,Deimling M,Huk WJ

更新日期：1995-01-01 00:00:00

abstract：:Steady-state free precession (SSFP) methods have gained widespread recognition for their ability to provide fast scans at high signal-to-noise ratio. This paper demonstrates that such methods are also capable of reflecting functional information, particularly blood oxygenation state. It is well known that SSFP signals...

journal_title：Magnetic resonance in medicine

authors： Dharmakumar R,Hong J,Brittain JH,Plewes DB,Wright GA

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:To develop and evaluate a method for volumetric contrast-enhanced MRI of the liver, with high spatial and temporal resolutions, for combined dynamic imaging and MR angiography (MRA) using a single injection of contrast agent. METHODS:An interleaved variable density (IVD) undersampling pattern was implemented i...

journal_title：Magnetic resonance in medicine

authors： Salmani Rahimi M,Korosec FR,Wang K,Holmes JH,Motosugi U,Bannas P,Reeder SB

更新日期：2015-03-01 00:00:00

abstract：:The authors introduce several sets of time-efficient gradient waveforms for applying isotropic diffusion weighting in NMR experiments. This creates signal attenuation that depends on the trace of the diffusion tensor and is therefore rotationally invariant. Numerical methods for the calculation of such gradient sets a...

journal_title：Magnetic resonance in medicine

authors： Wong EC,Cox RW,Song AW

更新日期：1995-08-01 00:00:00

abstract：:The experiments reported herein are the first MRI investigations of the orientational dependence of T(2) relaxation in articular cartilage at microscopic resolution over the 360 degrees angular space. For each of six canine cartilage specimens, 48 independent T(2)-weighted proton images were acquired for 12 different ...

journal_title：Magnetic resonance in medicine

authors： Xia Y,Moody JB,Alhadlaq H

更新日期：2002-09-01 00:00:00

abstract：:Gliomas are the most common primary brain tumors and the majority are highly malignant, with one of the worst prognoses for patients. Gliomas are characterized by invasive growth into normal brain tissue that makes complete surgical resection and accurate radiotherapy planning extremely difficult. We have performed in...

journal_title：Magnetic resonance in medicine

authors： Wright AJ,Fellows G,Byrnes TJ,Opstad KS,McIntyre DJ,Griffiths JR,Bell BA,Clark CA,Barrick TR,Howe FA

更新日期：2009-12-01 00:00:00

abstract：:A new method is presented for the quantitative determination of regional blood volumes in vivo. It is based on rapid quantitative T1 mapping by Snapshot FLASH MRI combined with the injection of an intravascular MR contrast agent. Regional blood volumes in four different tissues of the rat (skeletal muscle, heart, live...

journal_title：Magnetic resonance in medicine

authors： Schwarzbauer C,Syha J,Haase A

更新日期：1993-05-01 00:00:00

abstract：PURPOSE:To assess volumetric proton MR spectroscopic imaging (MRSI) of the human brain on multivendor MRI instruments. METHODS:Echo-planar spectroscopic imaging was developed on instruments from three manufacturers, with matched specifications and acquisition protocols that accounted for differences in sampling perfor...

journal_title：Magnetic resonance in medicine

authors： Sabati M,Sheriff S,Gu M,Wei J,Zhu H,Barker PB,Spielman DM,Alger JR,Maudsley AA

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:MRI-guided thermal ablations require reliable monitoring methods to ensure complete destruction of the diseased tissue while avoiding damage to the surrounding healthy tissue. Based on the fact that thermal ablations result in substantial changes in biomechanical properties, interventional MR elastography (MRE)...

journal_title：Magnetic resonance in medicine

authors： Corbin N,Vappou J,Breton E,Boehler Q,Barbé L,Renaud P,de Mathelin M

更新日期：2016-03-01 00:00:00

abstract：:In an effort to develop MRI methods for the evaluation of tumor angiogenesis (new blood vessel formation), MRI-derived cerebral blood volume (CBV) information has been compared to histologic measures of microvessel density (MVD). Although MVD is a standard marker of angiogenesis, it is not a direct correlate of the vo...

journal_title：Magnetic resonance in medicine

authors： Pathak AP,Schmainda KM,Ward BD,Linderman JR,Rebro KJ,Greene AS

更新日期：2001-10-01 00:00:00

abstract：:Perfusion imaging by arterial spin labeling (ASL) can be highly sensitive to the transit time from the labeling site to the tissue. We report the results of a study designed to separate the transit time and perfusion contributions to activation in ASL images accompanying motor and visual stimulation. Fractional transi...

journal_title：Magnetic resonance in medicine

authors： Gonzalez-At JB,Alsop DC,Detre JA

更新日期：2000-05-01 00:00:00

abstract：:We studied the fluxes of a potassium congener (Rb(+)) in mouse hearts by (87)Rb MRS at 8.4T. The hearts were loaded with Rb(+) by perfusion with Krebs-Henseleit buffer, in which 50% of K(+) was substituted with Rb(+). We initiated Rb(+) efflux by changing the perfusion medium to Rb(+)-free buffer. Spectra were acquire...

journal_title：Magnetic resonance in medicine

authors： Jilkina O,Xiang B,Kuzio B,Rendell J,Kupriyanov VV

更新日期：2005-05-01 00:00:00