In vivo validation of MR pulse pressure measurement in an aortic flow model: preliminary results.

Abstract:

:MR imaging experiments were conducted to investigate the feasibility of estimating vascular pulse pressure waveforms from measurements of blood flow rates and vessel cross-sectional area. Blood flow waveforms were measured in the aorta's of three 25-30-kg pigs at multiple imaging sections using phase-contrast velocity imaging. Estimates of pulse pressure were derived from these data by evaluating a model characterizing the relationship between pressure, flow, and the cross-sectional area of a vessel segment. Comparisons between the MR-derived estimates of pressure and those obtained from a micromanometer pressure catheter indicate that accurate measurements (mean error +/- SD = 8.2 +/- 3.4, n = 6) can be obtained using conventional velocity imaging techniques. Optimization of the method will require the application of rapid imaging techniques and the development of strategies for obtaining a more localized measurement. With these improvements, our results suggest that MR-based measurement of pulse pressure and related elastic parameters is feasible.

journal_name

Magn Reson Med

authors

Urchuk SN,Fremes SE,Plewes DB

doi

10.1002/mrm.1910380209

subject

Has Abstract

pub_date

1997-08-01 00:00:00

pages

215-23

issue

2

eissn

0740-3194

issn

1522-2594

journal_volume

38

pub_type

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