Measurement of fibrin concentration by fast field-cycling NMR.

abstract：PURPOSE:We sought to develop and test a clinically feasible 1-point Dixon, three-dimensional (3D) radial acquisition strategy to create isotropic 3D MR images of (129)Xe in the airspaces, barrier, and red blood cells (RBCs) in a single breath. The approach was evaluated in healthy volunteers and subjects with idiopathi...

journal_title：Magnetic resonance in medicine

authors： Kaushik SS,Robertson SH,Freeman MS,He M,Kelly KT,Roos JE,Rackley CR,Foster WM,McAdams HP,Driehuys B

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:High-resolution intravascular (IV) MRI is susceptible to degradation from physiological motion and requires high frame-rates for true endoscopy. Traditional cardiac-gating techniques compromise efficiency by reducing the effective scan rate. Here we test whether compressed sensing (CS) reconstruction and ungate...

journal_title：Magnetic resonance in medicine

authors： Hegde SS,Zhang Y,Bottomley PA

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:To exploit the improved comparability and hardware independency of quantitative MRI, databases of MR physical parameters in healthy tissue are required, to which tissue properties of patients can be compared. In this work, normative values for longitudinal and transverse relaxation times in the brain were estab...

journal_title：Magnetic resonance in medicine

authors： Piredda GF,Hilbert T,Granziera C,Bonnier G,Meuli R,Molinari F,Thiran JP,Kober T

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:To compare experimental transverse relaxivities of iron oxide nanocrystals (IONC) as a function of clustering and magnetic field strength with different theoretical model predictions. THEORY AND METHODS:Well-defined IONC clusters in nanoemulsions (NEs) of which both size and IONC loading could be judiciously t...

journal_title：Magnetic resonance in medicine

authors： Hak S,Goa PE,Stenmark S,Bjerkholt FF,Haraldseth O

更新日期：2015-09-01 00:00:00

abstract：:This article introduces a novel method named "Parallel Imaging and Noquist in Tandem" (PINOT) for accelerated image acquisition of cine cardiac magnetic resonance imaging. This method combines two prior information formalisms, the SPACE-RIP implementation of parallel imaging and the Noquist method for reduced-data ima...

journal_title：Magnetic resonance in medicine

authors： Hamilton LH,Fabregat JA,Moratal D,Ramamurthy S,Lerakis S,Parks WJ,Sallee D 3rd,Brummer ME

更新日期：2011-04-01 00:00:00

abstract：:A new approach to spin-echo imaging is presented in which the 180 degrees RF pulse refocuses two or more spin-echoes at different positions in the readout period. When simultaneous echo refocusing (SER) is implemented using multiple 180 degrees pulses, an undesirable mixing of stimulated echoes and primary echoes from...

journal_title：Magnetic resonance in medicine

authors： Günther M,Feinberg DA

更新日期：2005-09-01 00:00:00

abstract：PURPOSE:To assess the performance, in the presence of scanner instabilities, of three dynamic correction methods which integrate ∆B0 mapping into the chemical exchange saturation transfer (CEST) measurement and three established static ∆B0 -correction approaches. METHODS:A homogeneous phantom and five healthy voluntee...

journal_title：Magnetic resonance in medicine

authors： Poblador Rodriguez E,Moser P,Dymerska B,Robinson S,Schmitt B,van der Kouwe A,Gruber S,Trattnig S,Bogner W

更新日期：2019-08-01 00:00:00

abstract：:Slowly cycling cells are believed to play a critical role in tumor progression and metastatic dissemination. The goal of this study was to develop a method for in vivo detection of slowly cycling cells. To distinguish these cells from more rapidly proliferating cells that constitute the vast majority of cells in tumor...

journal_title：Magnetic resonance in medicine

authors： Magnitsky S,Roesch A,Herlyn M,Glickson JD

更新日期：2011-11-01 00:00:00

abstract：:Quantitative cerebral tissue volumes may be useful for an objective assessment of pathological changes in brain. Accurate determination of tissue volumes is complicated, however, by the partial volume averaging (PVA) effect. We have, therefore, developed a new pulse sequence that minimizes the PVA through the use of i...

journal_title：Magnetic resonance in medicine

authors： Bedell BJ,Narayana PA

更新日期：1998-06-01 00:00:00

abstract：:Experimental procedures for obtaining localized 31P NMR spectra of humans by means of the ISIS sequence are discussed in detail. The technique is optimized for use with volume coils and with surface coils in order to measure localized 31P NMR spectra of different tissues and organs. Selective frequency-modulated (FM) ...

journal_title：Magnetic resonance in medicine

authors： Luyten PR,Groen JP,Vermeulen JW,den Hollander JA

更新日期：1989-07-01 00:00:00

abstract：:Parallel imaging reconstructions result in spatially varying noise amplification characterized by the g-factor, precluding conventional measurements of noise from the final image. A simple Monte Carlo based method is proposed for all linear image reconstruction algorithms, which allows measurement of signal-to-noise r...

journal_title：Magnetic resonance in medicine

authors： Robson PM,Grant AK,Madhuranthakam AJ,Lattanzi R,Sodickson DK,McKenzie CA

更新日期：2008-10-01 00:00:00

abstract：:Strong, extensive magnetic fringe fields are a significant problem with magnetic resonance imaging magnets. This is particularly acute with 4-T, whole-body research magnets. To date this problem has been addressed by restricting an extensive zone around the unshielded magnet or by placing external unsaturated iron shi...

journal_title：Magnetic resonance in medicine

authors： Huson FR,Bryan RN,MacKay WW,Herrick RC,Colvin J,Ford JJ,Pissanetzky S,Plishker GA,Rocha R,Schmidt W

更新日期：1993-01-01 00:00:00

abstract：:Parallel imaging presents a promising approach for MRI of hyperpolarized nuclei, as the penalty in signal-to-noise ratio typically encountered with (1)H MRI due to a reduction in acquisition time can be offset by an increase in flip angle. The signal-to-noise ratio of hyperpolarized MRI generally exhibits a strong dep...

journal_title：Magnetic resonance in medicine

authors： Deppe MH,Parra-Robles J,Marshall H,Lanz T,Wild JM

更新日期：2011-12-01 00:00:00

abstract：:Acute normovolemic hemodilution (HD) was induced in anesthetized rats to assess the effect of changes in hematocrit (Hct) on signal intensity in T2*-weighted magnetic resonance (MR) images. Other relevant physiological parameters were maintained invariant. Two degrees of HD were induced: mild (Hct reduced from 42.6+/-...

journal_title：Magnetic resonance in medicine

authors： Lin W,Paczynski RP,Celik A,Hsu CY,Powers WJ

更新日期：1998-12-01 00:00:00

abstract：PURPOSE:To demonstrate the feasibility of imaging the first passage of a bolus of hyperpolarized (13)C urea through the rodent heart using flow-sensitizing gradients to reduce signal from the blood pool. METHODS:A flow-sensitizing bipolar gradient was optimized to reduce the bright signal within the cardiac chambers, ...

journal_title：Magnetic resonance in medicine

authors： Lau AZ,Miller JJ,Robson MD,Tyler DJ

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:Quantitative susceptibility mapping can be performed through the minimization of a function consisting of data fidelity and regularization terms. For data consistency, a Gaussian-phase noise distribution is often assumed, which breaks down when the signal-to-noise ratio is low. A previously proposed alternative...

journal_title：Magnetic resonance in medicine

authors： Milovic C,Bilgic B,Zhao B,Acosta-Cabronero J,Tejos C

更新日期：2018-08-01 00:00:00

abstract：PURPOSE:To design low peak and integrated power simultaneous multislice excitation radiofrequency pulses with transmit field inhomogeneity compensation in high field MRI. THEORY AND METHODS:The "interleaved greedy and local optimization" algorithm for small-tip-angle spokes pulses is extended to design multiband (MB) ...

journal_title：Magnetic resonance in medicine

authors： Sharma A,Bammer R,Stenger VA,Grissom WA

更新日期：2015-09-01 00:00:00

abstract：:This study demonstrates the feasibility of applying free-breathing, cardiac-gated, susceptibility-weighted fast spin-echo imaging together with black blood preparation and navigator-gated respiratory motion compensation for anatomically accurate T2* mapping of the heart. First, T2* maps are presented for oil phantoms ...

journal_title：Magnetic resonance in medicine

authors： Heinrichs U,Utting JF,Frauenrath T,Hezel F,Krombach GA,Hodenius MA,Kozerke S,Niendorf T

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:The correlation between glutamine metabolism and oncogene expression in cancers has led to a renewed interest in the role of glutamine in cancer cell survival. Hyperpolarized [5-(13) C]glutamine is evaluated as a potential biomarker for noninvasive metabolic measurements of drug response in prostate cancer cell...

journal_title：Magnetic resonance in medicine

authors： Canapè C,Catanzaro G,Terreno E,Karlsson M,Lerche MH,Jensen PR

更新日期：2015-06-01 00:00:00

abstract：:Detre et al. (Magn. Reson. Med. 23, 37-45 (1992)) and Zhang et al., (Magn. Reson. Med. 25, 362 (1992)) have recently demonstrated a technique for the measurement of regional cerebral blood flow (rCBF) based on the continuous saturation (or inversion) of the arterial blood supply to the brain in rats at 4.7 T. In the w...

journal_title：Magnetic resonance in medicine

authors： Walsh EG,Minematsu K,Leppo J,Moore SC

更新日期：1994-02-01 00:00:00

abstract：PURPOSE:The diseased myocardium lacks metabolic flexibility and responds to stimuli differently compared with healthy hearts. Here, we report the use of hyperpolarized 13C NMR spectroscopy to detect sudden changes in cardiac metabolism in isolated, perfused rat hearts in response to adrenergic stimulation. METHODS:Met...

journal_title：Magnetic resonance in medicine

authors： Khemtong C,Carpenter NR,Lumata LL,Merritt ME,Moreno KX,Kovacs Z,Malloy CR,Sherry AD

更新日期：2015-08-01 00:00:00

abstract：:Alternate methods to quantify mitochondrial activity or function have been extensively used for studying insulin resistance and type 2 diabetes mellitus, namely saturation transfer and phosphocreatine (PCr) recovery. As these methods are in fact determining different parameters, this study aimed to compare saturation ...

journal_title：Magnetic resonance in medicine

authors： Schmid AI,Schrauwen-Hinderling VB,Andreas M,Wolzt M,Moser E,Roden M

更新日期：2012-04-01 00:00:00

abstract：PURPOSE:The primary purpose of this study is to propose a method for the simultaneous quantitative three-dimensional (3D) mapping of conductivity and susceptibility using double-echo ultrashort echo time (UTE) imaging. The secondary purpose is to investigate the changes of these properties over time during in vitro hem...

journal_title：Magnetic resonance in medicine

authors： Gho SM,Shin J,Kim MO,Kim DH

更新日期：2016-07-01 00:00:00

abstract：:High-field MRI scanners are, in principle, well suited for mouse studies; however, many high-field magnets employ a vertical design that may influence the physiological state of the rodent. The purpose of this study was to investigate the orthostatic response of cerebral blood flow (CBF) in mice during a prolonged MR ...

journal_title：Magnetic resonance in medicine

authors： Foley LM,Hitchens TK,Kochanek PM,Melick JA,Jackson EK,Ho C

更新日期：2005-10-01 00:00:00

abstract：PURPOSE:To investigate a computationally efficient method for optimizing the Cramér-Rao Lower Bound (CRLB) of quantitative sequences without using approximations or an analytical expression of the signal. METHODS:Automatic differentiation was applied to Bloch simulations and used to optimize several quantitative seque...

journal_title：Magnetic resonance in medicine

authors： Lee PK,Watkins LE,Anderson TI,Buonincontri G,Hargreaves BA

更新日期：2019-10-01 00:00:00

abstract：:A potential relationship between structural compartments in neural tissue and NMR parameters may increase the specificity of MRI in diagnosing diseases. Nevertheless, our understanding of MR of nerves and white matter is limited, particularly the influence of various water compartments on the MR signal is not known. I...

journal_title：Magnetic resonance in medicine

authors： Peled S,Cory DG,Raymond SA,Kirschner DA,Jolesz FA

更新日期：1999-11-01 00:00:00

abstract：:Image selected in vivo spectroscopy (ISIS) is a volume selection method often used for in vivo (31)P MRS, since it is suitable for measurements of substances with short T(2). However, ISIS can suffer from significant signal contributions caused by T(1) smearing from regions outside the VOI. A computer model was develo...

journal_title：Magnetic resonance in medicine

authors： Ljungberg M,Starck G,Vikhoff-Baaz B,Alpsten M,Ekholm S,Forssell-Aronsson E

更新日期：2000-10-01 00:00:00

abstract：:A novel method, called relaxo-oximetry, for rapid spatially resolved in vivo measurements of oxygen concentration using time-domain radiofrequency (RF) electron paramagnetic resonance (EPR) is described. Time-domain data from triaryl methyl (TAM)-based single-electron contrast agents were processed by systematic delet...

journal_title：Magnetic resonance in medicine

authors： Subramanian S,Yamada K,Irie A,Murugesan R,Cook JA,Devasahayam N,Van Dam GM,Mitchell JB,Krishna MC

更新日期：2002-05-01 00:00:00

abstract：:Saline solutions of manganese ions (Mn2+) were used as articular contrast agents in magnetic resonance microscopy (9.4 T) of cartilage of chicken femoral condyles and pig temporomandibular joints. The diffusion of Mn2+ from the articular surface into the cartilage matrix led to a strong contrast enhancement in the car...

journal_title：Magnetic resonance in medicine

authors： Kusaka Y,Gründer W,Rumpel H,Dannhauer KH,Gersonde K

更新日期：1992-03-01 00:00:00

abstract：:The acquisition of complete three-dimensional (3D), segmented gradient-echo data sets to visualize the coronary arteries can be both time consuming and sensitive to motion, even with use of multiple breath-holding or respiratory gating. An alternate hybrid approach is demonstrated here, in which real-time interactive ...

journal_title：Magnetic resonance in medicine

authors： Hardy CJ,Darrow RD,Pauly JM,Kerr AB,Dumoulin CL,Hu BS,Martin KM

更新日期：1998-07-01 00:00:00