Abstract:
:The feasibility of MR subtraction imaging of lung ventilation using air against oxygen using a multiple inversion recovery half-Fourier single-shot turbo spin echo (MIR-HASTE) sequence was investigated. Eight healthy, nonsmoking volunteers (3 males, 5 females; from 27 to 48 years of age) were studied on a 1.5 T MR unit. The ventilation image was obtained from the subtraction of the images acquired with the subject inhaling room air and 100% oxygen. By suppressing the signal from subcutaneous fat and thoracic muscle, MIR-HASTE improved the subtraction of signal arising from background tissues. Lung parenchyma, pulmonary veins, descending aorta, spleen, and kidney showed high signal difference, but pulmonary arteries exhibited minimal signal difference. Because of minimal signal change in the pulmonary arteries after inhalation of 100% oxygen, the average signal decreases in the left and right lungs including hilus and periphery amounted to only 19.4+/-4.5 and 20.2+/-3.4%, respectively, compared with regional averages of 23.6+/-5.4 and 24.1+/-3.1% for both lung peripheries alone. Magn Reson Med 43:913-916, 2000.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Mai VM,Chen Q,Bankier AA,Edelman RRdoi
10.1002/1522-2594(200006)43:6<913::aid-mrm21>3.0.csubject
Has Abstractpub_date
2000-06-01 00:00:00pages
913-6issue
6eissn
0740-3194issn
1522-2594pii
10.1002/1522-2594(200006)43:6<913::AID-MRM21>3.0.Cjournal_volume
43pub_type
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