Abstract:
:According to our previously proposed auto-addiction hypothesis of chronic anorexia nervosa, patients become addicted to an initial period of dieting through endogenous opioid mediated mechanisms. Morphine causes hyperactivity and anorexia in the mouse, symptoms of anorexia nervosa but responses opposite to those of most species including rats and normal human subjects. This suggests that the atypical opioid systems in the mouse may resemble those of the chronic anorexia nervosa patient in contrast to those of most species including the normal human. Characterization of this atypical opioid system may be useful in understanding the pathophysiology of anorexia nervosa.
journal_name
Life Scijournal_title
Life sciencesauthors
Buck M,Marrazzi MAdoi
10.1016/0024-3205(87)90457-7subject
Has Abstractpub_date
1987-08-10 00:00:00pages
765-73issue
6eissn
0024-3205issn
1879-0631pii
0024-3205(87)90457-7journal_volume
41pub_type
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