Ultrastructural changes in skeletal muscles of rats treated neonatally with 6-mercaptopurine.

abstract：:Oxidative stress is accepted as a potential responsible mechanism in the pathogenesis of radiocontrast media (RCM)-induced hepatotoxicity. Therefore, we aimed to investigate the protective effects of ebselen against RCM-induced hepatotoxicity by measuring tissue oxidant/antioxidant parameters and histological changes ...

journal_title：Toxicology and industrial health

authors： Basarslan F,Yilmaz N,Davarci I,Akin M,Ozgur M,Yilmaz C,Ulutas KT

更新日期：2013-09-01 00:00:00

abstract：:Significant numbers of chemicals have been shown to be carcinogenic in mouse liver although they do not exhibit carcinogenic activity in other organs or tissues of mice or rats. This review focuses on the reasons for the unique susceptibility of the mouse liver to these carcinogens and the extent to which the carcinog...

journal_title：Toxicology and industrial health

authors： Pereira MA

更新日期：1985-12-01 00:00:00

abstract：:Octamethylcyclotetrasiloxane (D4; CAS No. 556-67-2) is used as a monomer in the manufacture of polymeric materials, which are widely used in various industrial and/or medical applications, such as breast implants. D4 has a relatively low order of toxicity following acute administration via the oral, dermal, and inhala...

journal_title：Toxicology and industrial health

authors：

更新日期：2017-01-01 00:00:00

abstract：:The objective of this study was to examine the potential of arsenate to induce cardiomyocyte cell death and to explore the cellular mechanisms of arsenate toxicity. Isolated cardiomyocytes in culture from embryonic chick hearts were treated with a pentavalent arsenic species (H3AsO4) or arsenate. Arsenate produced a s...

journal_title：Toxicology and industrial health

authors： Luong MW,Rabkin SW

更新日期：2009-04-01 00:00:00

abstract：:Electrical and electronic waste (E-waste) has now become the fastest growing solid waste around the world. Primitive recycling operations for E-waste have resulted in severe contamination of toxic metals and organic chemicals in the related areas. In this study, six dust and soil samples collected from E-waste recycli...

journal_title：Toxicology and industrial health

authors： Wang L,Hou M,An J,Zhong Y,Wang X,Wang Y,Wu M,Bi X,Sheng G,Fu J

更新日期：2011-10-01 00:00:00

abstract：:The antioxidant power of the so-called antioxidants is negligible because their rate constants and concentrations are too small to compete with the specialized defense enzymes, like superoxide dismutase (SOD), for the reactive oxygen species. In this short review, we present a number of experimental data of our group,...

journal_title：Toxicology and industrial health

authors： Koltover VK

更新日期：2009-05-01 00:00:00

abstract：:Hepatocarcinogens are agents that increase the incidence of liver cancer in exposed animals or humans. It is now established that carcinogenic exposures have a widespread impact on the transcriptome, inducing both adaptive and adverse changes in the activities of genes and pathways. Chemical hepatocarcinogens have als...

journal_title：Toxicology and industrial health

authors： Nicolaidou V,Koufaris C

更新日期：2020-05-01 00:00:00

abstract：:Endothelial adhesion plays an important role in the process of atherosclerosis, which is regulated by endothelial adhesion molecules and chemoattractant molecules. In some areas of China, citreoviridin (CIT) is considered a risk factor for the development of atherosclerosis. Here, we investigated the role of CIT in ad...

journal_title：Toxicology and industrial health

authors： Hou H,Zhou R,Jia Q,Li Q,Kang L,Jiao P,Li D,Jiang B

更新日期：2015-03-01 00:00:00

abstract：:This report reviews the literature on the impact of exposure to trichloroethylene (TCE) on human health. Special emphasis is given to the health effects reported in excess of national norms by participants in the TCE Subregistry of the Volatile Organic Compounds Registry of the National Exposure Registries--persons wi...

journal_title：Toxicology and industrial health

authors： Gist GL,Burg JR

更新日期：1995-05-01 00:00:00

abstract：:Zinc oxide nanoparticles (ZnONP) are manufactured on a large scale and can be found in a variety of consumer products, such as sunscreens, lotions, paints and food additives. Few studies have been carried out on its genotoxic potential and related mechanisms in whole organisms. In the present study, the in vivo genoto...

journal_title：Toxicology and industrial health

authors： Carmona ER,Inostroza-Blancheteau C,Rubio L,Marcos R

更新日期：2016-12-01 00:00:00

abstract：:Nanomaterials are widely used nowadays in a range of technological and biomedical fields. Graphene as a nanomaterial used in the health-care sector and in workplaces has raised some concerns about its toxicity. This study aimed to evaluate the cytotoxicity of graphene nanoparticles (GNPs) on the A549 epithelial cells ...

journal_title：Toxicology and industrial health

authors： Nasirzadeh N,Azari MR,Rasoulzadeh Y,Mohammadian Y

更新日期：2019-01-01 00:00:00

abstract：:Wild alligators exposed to persistent organochlorine contaminants, municipal waste compounds, and contemporary-use herbicides exhibit reproductive alterations that are thought to be caused by endocrine disruption. This study tests the hypothesis that these alterations, at least in part, result from exposure of alligat...

journal_title：Toxicology and industrial health

authors： Crain DA,Spiteri ID,Guillette LJ Jr

更新日期：1999-01-01 00:00:00

abstract：:We recently determined that the metabolism of a series of tumorigenic pyrrolizidine alkaloids resulted in the formation of a set of 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine (DHP)-derived DNA adducts. These DHP-derived DNA adducts have been proposed as potential biomarkers of pyrrolizidine alkaloid tumorige...

journal_title：Toxicology and industrial health

authors： Chou MW,Fu PP

更新日期：2006-09-01 00:00:00

abstract：:Phthalates are abundantly produced plasticizers, and dibutyl phthalate (DBP) is the most widely used derivative in various consumer products and medical devices. This study was conducted to further explore the potential testicular toxicity of DBP in adult rats and to elucidate the underlying mechanisms. Adult male alb...

journal_title：Toxicology and industrial health

authors： Aly HA,Hassan MH,El-Beshbishy HA,Alahdal AM,Osman AM

更新日期：2016-08-01 00:00:00

abstract：:A preliminary study of dermal and respiratory exposure to chlorpyrifos (Dursban TC) during structural treatments was conducted with eight workers from a commercial pest control company. The compound was applied by sub-slab and soil injection to four houses, with each application involving two workers. Crawl space appl...

journal_title：Toxicology and industrial health

authors： Fenske RA,Elkner KP

更新日期：1990-05-01 00:00:00

abstract：:Maneb is a dithiocarbamate fungicide that contains manganese. Dithiocarbamates are considered to be chemicals of low toxicity. An experimental group (n = 10) received maneb (obtained from Hoecht-Shering) at a concentration of 250 ppm in distilled water five days a week (treatment time is three weeks). It was orally ad...

journal_title：Toxicology and industrial health

authors： Deveci E

更新日期：2006-10-01 00:00:00

abstract：:The morphological changes of ricin-induced apoptosis in a human cervical cancer cell line were studied. To shed light on the mechanism of action of ricin toxin (RT) at the cellular level, we examined cell growth, apoptosis, changes of mitochondrial membrane potential (MMP) and cytochrome C translocation in HeLa cells ...

journal_title：Toxicology and industrial health

authors： Liao P,Liu W,Li H,Gao H,Wang H,Li N,Xu N,Li J,Wan J,Liu L,Sun Y

更新日期：2012-06-01 00:00:00

abstract：:The risk assessment process must encompass all available toxicological data and scientific evidence on the plausible toxicities of a chemical or chemical mixture. As an extension to the approaches used to conduct risk assessments on chemical mixtures, a preliminary scheme, analogous to the IARC classification of carci...

journal_title：Toxicology and industrial health

authors： Mumtaz MM,Durkin PR

更新日期：1992-11-01 00:00:00

abstract：:This study was designed to determine if long-term exposure to high doses of methoxychlor (M) would alter pituitary or testicular endocrine functions in either an estrogenic or antiandrogenic manner. Weanling male Long-Evans hooded rats were dosed daily with M (po) at 0, 200, 300, or 400 mg kg-1 day-1 for 10 months. Me...

journal_title：Toxicology and industrial health

authors： Gray LE Jr,Ostby J,Cooper RL,Kelce WR

更新日期：1999-01-01 00:00:00

abstract：:Adult female Swiss Webster and B6C3F1 mice received distilled water only or water containing 0.1, 1.0, 10, 100 or 1000 ppb of aldicarb daily for 34 days. The target concentration of aldicarb present in the 10 ppb dosing solution was analytically verified on a daily basis as was its stability over a 48-hr period. To de...

journal_title：Toxicology and industrial health

authors： Thomas PT,Ratajczak HV

更新日期：1988-09-01 00:00:00

abstract：:Zinc oxide nanoparticles (ZnO NPs) are produced in high tonnage each year; they are widely used in consumer and industrial products, also now finding applications in bioimaging and drug delivery. In the present study, comparison between ZnO NPs (39 nm) and its bulk/micron form (particle size = 5 µm) on liver function ...

journal_title：Toxicology and industrial health

authors： Moatamed ER,Hussein AA,El-Desoky MM,Khayat ZE

更新日期：2019-10-01 00:00:00

abstract：:Brominated flame retardants (BFRs) and heavy metals (HMs) are two main types of pollutants in electronic waste recycling sites, which are also ubiquitously detectable in environmental media and human tissues. However, the adverse health effects of exposure to the mixture of these types of pollutants are unknown. In th...

journal_title：Toxicology and industrial health

authors： Chen J,Ma X,Tian L,Kong A,Wang N,Huang C,Yang D

更新日期：2018-09-01 00:00:00

abstract：:Organophosphate (OP) compounds are the most commonly used pesticide groups and they are commercially used in the market for local and industrial purposes. Paraoxonase 1 (PON1) enzyme plays an important role in biotransformation of OP compounds, which shows toxic effects via inhibiting the acetylcholinesterase (AChE). ...

journal_title：Toxicology and industrial health

authors： Sunay SZ,Kayaaltı Z,Bayrak T,Söylemezoğlu T

更新日期：2015-12-01 00:00:00

abstract：:Chloroethane (CE) gas carcinogenicity is analyzed and determined from a National Toxicology Program (NTP) bioassay where an inhalation concentration of 15,000 ppm CE gas in air produced the highest incidence of an uncommon-to-rare tumor ever observed by the NTP. Persistently inhaled CE produces endometrial cancers in ...

journal_title：Toxicology and industrial health

authors： Holder JW

更新日期：2008-11-01 00:00:00

abstract：:T-2 toxin is one of the mycotoxins, a group of type A trichothecenes produced by several fungal genera including Fusarium species, which may lead to the decrease of testosterone secretion in primary Leydig cells derived from mouse testis. The previous study demonstrated T-2 toxin decrease the testosterone biosynthesis...

journal_title：Toxicology and industrial health

authors： Yang JY,Zhang YF,Li YX,Guan GP,Kong XF,Liang AM,Ma KW,Da Li G,Bai XF

更新日期：2016-10-01 00:00:00

abstract：:Carbendazim is a broad spectrum carbamate fungicide used in the control of various fungal pathogens. Licorice (Glycyrrhiza glabra) is one of the widely used medicinal plants in oriental nations. The present work studied the effect of licorice aqueous extract on carbendazim-induced testicular toxicity in albino rats. A...

journal_title：Toxicology and industrial health

authors： Sakr SA,Shalaby SY

更新日期：2014-04-01 00:00:00

abstract：:The present paper summarizes the proposed time-dependent sensitization (TDS) and partial limbic kindling model for illness from low-level chemicals; reviews and critiques prior studies on CNS aspects of multiple chemical sensitivity (MCS); and outlines possible experimental approaches to future studies. TDS is the pro...

journal_title：Toxicology and industrial health

authors： Bell IR

更新日期：1994-07-01 00:00:00

abstract：:The effect of copper in form of copper sulphate (CuSO4 x 5 H2O) was studied in the bone marrow cells of rats of Wistar strain in an in vitro culture. Evident differences between tissue cultures of the bone marrow cells were observed between the control and experimental groups. In the experimental group, the CFU-F colo...

journal_title：Toxicology and industrial health

authors： Miszta H

更新日期：1989-12-01 00:00:00

abstract：:The aim of the present study was to provide baseline data on the prevalence of histopathological liver lesions in Acanthopagrus latus under experimental mercury exposure. Experimental study was at seawater recirculatory tanks. Mercury concentrations were determined using a standard cold vapour atomic absorption. Histo...

journal_title：Toxicology and industrial health

authors： Safahieh A,Hedayati A,Savari A,Movahedinia A

更新日期：2012-08-01 00:00:00

abstract：:The mechanism by which granulocyte colony-stimulating factor (G-CSF) could lead to the protection from liver injury is not well known. Therefore, the resolution of this role needs further basic and clinical experimental investigation. Acute liver injury was induced in rats by single intraperitoneal injection of a 0.50...

journal_title：Toxicology and industrial health

authors： Qujeq D,Abassi R,Faeizi F,Parsian H,Faraji AS,Taheri H,Tatar M,Elmi MM,Halalkhor S

更新日期：2013-07-01 00:00:00