An assessment of the cytotoxic effects of graphene nanoparticles on the epithelial cells of the human lung.

abstract：:Medicinal plants are increasingly being projected as suitable alternative source for the treatment of various diseases. However, toxic effects resulting from therapeutic bismuth compounds are still documented in animals and humans. This study described the genetic effects of five common lichen species and compared the...

journal_title：Toxicology and industrial health

authors： Geyikoglu F,Turkez H,Aslan A

更新日期：2007-09-01 00:00:00

abstract：:This paper describes the development and implementation of physiologically-based pharmacokinetic (PB-Pk) models to examine the disposition of xenobiotics and their bioactivation. In a PB-Pk model, the structure of the model is based, to as great extent as practicable, on the actual physiological and biochemical struct...

journal_title：Toxicology and industrial health

authors： Clewell HJ 3rd,Andersen ME

更新日期：1994-01-01 00:00:00

abstract：:Enzymes with hydroxylating activity on alkanes have potential application as biotransformation catalysts in chemical and pharmaceutical industry. Genome of Alcanivorax borkumensis, a marine bacterium with hydrocarbon dissimilation activity, contains at least two P450 monooxygenases and two nonheme monooxygenases, AlkB...

journal_title：Toxicology and industrial health

authors： Eidani SZ,Shahraki MK,Gasemisakha F,Hahsemi M,Bambai B

更新日期：2012-07-01 00:00:00

abstract：:Forty-nine female workers in the shoemaking industry, exposed to a solvent mixture containing benzene and twenty-seven non-exposed controls, were investigated. Concentrations of benzene and toluene in the working atmosphere, as well as benzene and toluene in blood and phenols in pre- and post-shift urine as parameters...

journal_title：Toxicology and industrial health

authors： Bogadi-Sare A,Turk R,Karacić V,Zavalić M,Trutin-Ostović K

更新日期：1997-07-01 00:00:00

abstract：:Groups of five male and five female rats were fed diets containing from 0% to 2.5% di(2-ethylhexyl)terephthalate (DEHT) or 1.2% di(2-ethylhexyl)phthalate (DEHP) for 21 days. Feed consumption and body weight gains were collected and, at study termination, animals were examined for alterations in body weight, difference...

journal_title：Toxicology and industrial health

authors： Topping DC,Ford GP,Evans JG,Lake BG,O'Donoghue JL,Lockhart HB Jr

更新日期：1987-06-01 00:00:00

abstract：:In the last few decades the need for new approaches to assess DNA damage has been increasing due to the implications that different insults on genetic material may have on human health. In this context, the identification of how chemical agents with different mechanisms of action (i.e., antineoplastic drugs) damage DN...

journal_title：Toxicology and industrial health

authors： Mussali-Galante P,Avila-Costa MR,Piñón-Zarate G,Martínez-Levy G,Rodríguez-Lara V,Rojas-Lemus M,Avila-Casado MC,Fortoul TI

更新日期：2005-09-01 00:00:00

abstract：:Some studies have shown that exposure to electromagnetic field (EMF) may result in structural damage to neurons. In this study, we have elucidated the alteration in the hippocampal function of offspring Wistar rats (n = 8 rats in each group) that were chronically exposed to mobile phones during their gestational perio...

journal_title：Toxicology and industrial health

authors： Razavinasab M,Moazzami K,Shabani M

更新日期：2016-06-01 00:00:00

abstract：:Occupational exposure in a copper smelting industry may produce various adverse health effects including cancer. Despite a number of well-documented studies reporting an increased risk of cancer among copper smelter workers, the data on genotoxic effects in this industry are scarce. In view of the above, an assessment...

journal_title：Toxicology and industrial health

authors： De Olivera JV,Boufleur LA,Dos Santos CE,Dias JF,Squeff CH,Silva GR,Ianistcki M,Benvegnú VC,Da Silva J

更新日期：2012-10-01 00:00:00

abstract：:Pesticides are registered in Canada under the authority of the Pest Control Products Act (PCP), administered by the Department of Agriculture. The Department of Agriculture calls upon various federal departments, including Health & Welfare Canada, to provide expert advice on hazards which may be associated with the us...

journal_title：Toxicology and industrial health

authors： Ritter L,Curry PB

更新日期：1988-09-01 00:00:00

abstract：:Endocrine disrupting chemicals (EDCs) are defined as exogenous substances that can alter the development and functioning of the endocrine system. The Wnt signaling pathway is an evolutionarily conserved pathway consisting of proteins that transmit cell-to-cell receptors through cell surface receptors, regulating impor...

journal_title：Toxicology and industrial health

authors： Üstündağ ÜV,Emekli-Alturfan E

更新日期：2020-01-01 00:00:00

abstract：:Oxidative stress is accepted as a potential responsible mechanism in the pathogenesis of radiocontrast media (RCM)-induced hepatotoxicity. Therefore, we aimed to investigate the protective effects of ebselen against RCM-induced hepatotoxicity by measuring tissue oxidant/antioxidant parameters and histological changes ...

journal_title：Toxicology and industrial health

authors： Basarslan F,Yilmaz N,Davarci I,Akin M,Ozgur M,Yilmaz C,Ulutas KT

更新日期：2013-09-01 00:00:00

abstract：:Brominated flame retardants (BFRs) and heavy metals (HMs) are two main types of pollutants in electronic waste recycling sites, which are also ubiquitously detectable in environmental media and human tissues. However, the adverse health effects of exposure to the mixture of these types of pollutants are unknown. In th...

journal_title：Toxicology and industrial health

authors： Chen J,Ma X,Tian L,Kong A,Wang N,Huang C,Yang D

更新日期：2018-09-01 00:00:00

abstract：:The mechanism by which granulocyte colony-stimulating factor (G-CSF) could lead to the protection from liver injury is not well known. Therefore, the resolution of this role needs further basic and clinical experimental investigation. Acute liver injury was induced in rats by single intraperitoneal injection of a 0.50...

journal_title：Toxicology and industrial health

authors： Qujeq D,Abassi R,Faeizi F,Parsian H,Faraji AS,Taheri H,Tatar M,Elmi MM,Halalkhor S

更新日期：2013-07-01 00:00:00

abstract：:Mercury has been used in many domains of human activities for many years, although in any form mercury is reported to be toxic. On the other hand, lichens have been used in the treatment of several diseases such as tuberculosis, hemorrhoids, ulcer, dysentery and cancer. Animal investigations on some common lichen spec...

journal_title：Toxicology and industrial health

authors： Turkez H,Dirican E

更新日期：2012-02-01 00:00:00

abstract：:Trivalent chromium (Cr) is an environmental contaminant, which is extensively used in tanning industries throughout the world and causes various forms of health hazards in tannery workers. Therefore, a cross-sectional study design was used to evaluate the DNA damage and oxidative stress condition in tannery workers ex...

journal_title：Toxicology and industrial health

authors： Ambreen K,Khan FH,Bhadauria S,Kumar S

更新日期：2014-06-01 00:00:00

abstract：:The risk assessment process must encompass all available toxicological data and scientific evidence on the plausible toxicities of a chemical or chemical mixture. As an extension to the approaches used to conduct risk assessments on chemical mixtures, a preliminary scheme, analogous to the IARC classification of carci...

journal_title：Toxicology and industrial health

authors： Mumtaz MM,Durkin PR

更新日期：1992-11-01 00:00:00

abstract：:The objective is to present historical asbestos airborne concentrations associated with activities involving presumably asbestos-containing materials in steel mills. A total of 138 historical industrial hygiene air samples collected in three US steel mills from 1972 to 1982 were analyzed. The majority of samples were ...

journal_title：Toxicology and industrial health

authors： Hollins D,Burns A,Unice K,Paustenbach DJ

更新日期：2019-11-01 00:00:00

abstract：:Chloropentafluorobenzene (CPFB) has been identified as a candidate simulant for nonpersistent chemical warfare agents. Acute toxicity studies have shown that CPFB has limited adverse effects on laboratory animals. A 21-day inhalation study of rats and mice to 2.5, 0.8, and 0.25 mg CPFB/liter resulted in reduced weight...

journal_title：Toxicology and industrial health

authors： Kinkead ER,Bunger SK,Kimmel EC,Flemming CD,Wall HG,Grabau JH

更新日期：1991-07-01 00:00:00

abstract：:Penile fracture (PF) is known as a traumatic rupture of the tunica albuginea of corpus cavernosum. In this study, we aimed to investigate the healing influence of topical extra virgin olive oil (EVOO) on PF through evaluating levels of some oxidative stress biomarkers for the first time. Histopathological evaluation w...

journal_title：Toxicology and industrial health

authors： Gunes M,Ozkol H,Pirincci N,Gecit I,Bilici S,Yildirim S

更新日期：2015-08-01 00:00:00

abstract：:The inhalation toxicity of methanol and toluene was investigated in rats. Young Sprague Dawley rats of both sexes were exposed to vapors of methanol (300 ppm, 3000 ppm), toluene (30 ppm, 300 ppm) or methanol/toluene (300/30 ppm, 300/300 ppm, 3000/30 ppm, and 3000/300 ppm) six hrs per day, five days/week for four weeks...

journal_title：Toxicology and industrial health

authors： Poon R,Chu I,Bjarnason S,Potvin M,Vincent R,Miller RB,Valli VE

更新日期：1994-05-01 00:00:00

abstract：:Some studies have shown increased DNA damage among car painters, but other professionals working in auto body and paint shops have not been extensively assessed. The aim of this study was to assess DNA damage in different types of auto body shop workers by measuring micronucleus (MN) levels in exfoliated buccal cells....

journal_title：Toxicology and industrial health

authors： Siebel AM,Basso da Silva L

更新日期：2010-10-01 00:00:00

abstract：INTRODUCTION:Semiconductor quantum dots (QDs), especially those containing cadmium, have undergone marked improvements and are now widely used nanomaterials in applicable biological fields. However, great concerns exist regarding their toxicity in biomedical applications. Because of the lack of sufficient data regardin...

journal_title：Toxicology and industrial health

authors： Naderi S,Zare H,Taghavinia N,Irajizad A,Aghaei M,Panjehpour M

更新日期：2018-05-01 00:00:00

abstract：:In summary, we have described our method of treating phosgene inhalation injury. We have presented two serious cases in detail which demonstrate that survival was associated with aggressive therapy. Several points should be mentioned. The pulmonary edema and resulting fluid and foam production can be so copious as to ...

journal_title：Toxicology and industrial health

authors： Regan RA

更新日期：1985-10-01 00:00:00

abstract：:The bromoalkane, 1-bromopropane (1-BP), may damage the reproductive system though oxidative stress, while the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) plays an important role in regulating intracellular antioxidant levels against oxidative stress. This study explored the role of oxidativ...

journal_title：Toxicology and industrial health

authors： Yang G,Xiang Y,Zhou W,Zhong X,Zhang Y,Lin D,Huang X

更新日期：2020-12-11 00:00:00

abstract：:An analytical method using natural analcime zeolite modified with tppz (2,3,5,6-tetra-pyridylpyrazine) for preconcentration of cadmium, in a column system, and their sequential determination by flame atomic absorption spectrometry (FAAS), was developed. In this work, cadmium was adsorbed onto natural analcime zeolite ...

journal_title：Toxicology and industrial health

authors： Saljooghi AS,Saljoghi ZS

更新日期：2012-10-01 00:00:00

abstract：:We recently determined that the metabolism of a series of tumorigenic pyrrolizidine alkaloids resulted in the formation of a set of 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine (DHP)-derived DNA adducts. These DHP-derived DNA adducts have been proposed as potential biomarkers of pyrrolizidine alkaloid tumorige...

journal_title：Toxicology and industrial health

authors： Chou MW,Fu PP

更新日期：2006-09-01 00:00:00

abstract：:Acrylamide has been discovered in foods cooked at high temperature. A potentially harmful effect of this dietary component has been suggested by data indicating its association with increased breast cancer. This study investigated the potential effects of acrylamide in nontumorigenic breast cells by assessing expressi...

journal_title：Toxicology and industrial health

authors： Lyn-Cook LE Jr,Tareke E,Word B,Starlard-Davenport A,Lyn-Cook BD,Hammons GJ

更新日期：2011-02-01 00:00:00

abstract：:Sorption of three pesticides on geologic material ranging in organic carbon content from 0.33 to 6.9 g kg-1 was measured in soil columns using a miscible displacement technique. An octanol-water partitioning model was shown to be inappropriate for predicting sorption of the less hydrophobic pesticides on the low organ...

journal_title：Toxicology and industrial health

authors： Bouchard DC,Wood AL

更新日期：1988-09-01 00:00:00

abstract：:An investigation was conducted to evaluate the ability of two chelators, deferasirox and desferrioxamine (DFO), in removing cadmium from biological system. The potential efficiency of those chelators were investigated after cadmium administration for 60 days following two dose levels of 20 and 40 mg/kg body weight dai...

journal_title：Toxicology and industrial health

authors： Fatemi SJ,Saljooghi AS,Balooch FD,Iranmanesh M,Golbafan MR

更新日期：2012-02-01 00:00:00

abstract：:The purpose of this study was to describe for asthmatic subjects the distribution of individual bronchial sensitivity to sulfur dioxide (SO2). Subjects were nonsmoking male asthmatics (n = 27) who were sensitive to inhaled methacholine. None of the subjects used corticosteroids or cromolyn sodium. Oral medications wer...

journal_title：Toxicology and industrial health

authors： Horstman D,Roger LJ,Kehrl H,Hazucha M

更新日期：1986-09-01 00:00:00