Abstract:
:The effect of copper in form of copper sulphate (CuSO4 x 5 H2O) was studied in the bone marrow cells of rats of Wistar strain in an in vitro culture. Evident differences between tissue cultures of the bone marrow cells were observed between the control and experimental groups. In the experimental group, the CFU-F colonies appeared as early as in 3rd day while in the control group in 5th day. Loosely arranged fibroblasts, macrophages and adipocytes also showed quantitative differences between groups. An increase in mean corpuscular hemoglobin (MCH) was also found in peripheral blood of experimental animals.
journal_name
Toxicol Ind Healthjournal_title
Toxicology and industrial healthauthors
Miszta Hdoi
10.1177/074823378900500617subject
Has Abstractpub_date
1989-12-01 00:00:00pages
1117-23issue
6eissn
0748-2337issn
1477-0393journal_volume
5pub_type
杂志文章abstract::Lead (Pb) is one of several environmental pollutants that adversely affect human health by producing toxicity at the tissue level. The aim of the study was to understand the effects of Pb on the metabolic profiles of liver and gastrocnemius muscle of mice in relation to carbohydrate and fat metabolisms. Swiss albino m...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233720937196
更新日期:2020-07-01 00:00:00
abstract::The effects of trona (Kaun), a food additive, on the redox status of the liver and kidney of male Wistar rats were investigated. A total of 60 male rats (145 ± 2.52 g) were grouped into four: A, B, C and D, where group A (the control) received 1 mL of distilled water orally while those in groups B, C and D (test group...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233712469654
更新日期:2015-02-01 00:00:00
abstract::Aluminum (Al) is commonly used in industrial processes and drugs and is thought to induce erythrocytes damage via activation of oxidative stress. Recently, bismuth (Bi)-containing drugs are used in the treatment of various diseases. However, uncertain effects of Bi in blood tissue may participate in the therapeutic ef...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233710381894
更新日期:2011-03-01 00:00:00
abstract::The risk assessment process must encompass all available toxicological data and scientific evidence on the plausible toxicities of a chemical or chemical mixture. As an extension to the approaches used to conduct risk assessments on chemical mixtures, a preliminary scheme, analogous to the IARC classification of carci...
journal_title:Toxicology and industrial health
pub_type: 杂志文章,评审
doi:
更新日期:1992-11-01 00:00:00
abstract::'Toxicant-induced loss of tolerance' (or TILT) describes a two-step disease process in which (1) certain chemical exposures, e.g., indoor air contaminants, chemical spills, or pesticide applications, cause certain susceptible persons to lose their prior natural tolerance for common chemicals, foods, and drugs (initiat...
journal_title:Toxicology and industrial health
pub_type: 杂志文章,评审
doi:10.1177/074823379901500302
更新日期:1999-04-01 00:00:00
abstract::Acetaminophen (APAP) is widely used in the treatment of pain. Toxic doses of APAP cause acute liver failure, but therapeutic doses are believed to be safe. The purpose of this study is to investigate the effects of administration of subtoxic doses of APAP on liver and blood levels of insulin-like growth factor-1 (IGF-...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233713498439
更新日期:2016-01-01 00:00:00
abstract::Cucumbers grown in two different greenhouses were exposed to mancozeb and carbaryl at different times. The effects of 10-day preharvest period, water and detergent washing, peeling, predetermined storage period at 4°C (refrigeration), and fermentation on the reduction of residue levels in the plant tissues were invest...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233714552295
更新日期:2016-06-01 00:00:00
abstract::The purpose of this study is to follow-up the distribution, lethality percentile doses (LDs) and bioaccumulation of aluminium oxide nanoparticles (Al2O3-NPs, average diameter 9.83 ± 1.61 nm) in some tissues of male albino rats, and to evaluate its genotoxicity to the brain tissues, during acute and sublethal experimen...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233713498449
更新日期:2016-02-01 00:00:00
abstract::The Agency for Toxic Substances and Disease Registry (ATSDR) prepared this health consultation to provide support for assessing the public health implications of hazardous chemical exposure, primarily through drinking water, related to releases of chromated copper arsenate (CCA) in the port of Djibouti. CCA from a shi...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233707076810
更新日期:2007-05-01 00:00:00
abstract::The mechanism by which granulocyte colony-stimulating factor (G-CSF) could lead to the protection from liver injury is not well known. Therefore, the resolution of this role needs further basic and clinical experimental investigation. Acute liver injury was induced in rats by single intraperitoneal injection of a 0.50...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233712440136
更新日期:2013-07-01 00:00:00
abstract::In summary, we have described our method of treating phosgene inhalation injury. We have presented two serious cases in detail which demonstrate that survival was associated with aggressive therapy. Several points should be mentioned. The pulmonary edema and resulting fluid and foam production can be so copious as to ...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/074823378500100207
更新日期:1985-10-01 00:00:00
abstract::In this study, we investigated the protective effect of pentoxifilline (PTX) on smoking-induced damage in rat kidney tissues. Twenty-seven male Wistar rats were used in the study. Animals were divided into three equal groups as follows: Group 1: control group with only normal saline (NS; 0.9% NaCl) injection for 8 wee...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233710387006
更新日期:2011-05-01 00:00:00
abstract::The following is a review of some of the work we have done since 2004 regarding the importance of molds and their mycotoxins in the phenomenon of sick building syndrome (SBS). In these studies we showed that the macrocyclic trichothecene mycotoxins (MTM) of Stachybotrys chartarum (SC) are easily dissociated from the s...
journal_title:Toxicology and industrial health
pub_type: 杂志文章,评审
doi:10.1177/0748233709348287
更新日期:2009-10-01 00:00:00
abstract::In this study, the cytotoxic potential of fluoride and endosulfan in combination was investigated in Swiss albino mice bone marrow cells using the chromosomal aberration (CA) and micronucleus (MN) test systems. Fluoride (25.1 mg kg-1 body weight [bw] in water) and endosulfan (1.8 mg kg-1 bw by oral intubation) were ad...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233720979423
更新日期:2020-12-16 00:00:00
abstract::The human teratogenic potential of chlordiazepoxide is debated. To study the effects on the fetal development of very large doses of chlordiazepoxide that were used for a suicide attempt during pregnancy, self-poisoned pregnant women were identified from patients in a toxicological inpatient clinic in Budapest, Hungar...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233708089018
更新日期:2008-02-01 00:00:00
abstract::T-2 toxin is one of the mycotoxins, a group of type A trichothecenes produced by several fungal genera including Fusarium species, which may lead to the decrease of testosterone secretion in primary Leydig cells derived from mouse testis. The previous study demonstrated T-2 toxin decrease the testosterone biosynthesis...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233715590516
更新日期:2016-10-01 00:00:00
abstract::The developmental toxicity of 2,4-Pentanedione (2,4-PD; CAS No. 123-54-6), a widely used industrial chemical, was investigated by vapour exposure, because of its widespread use, and potential for human exposure. Timed-pregnant Fischer 344 rats were exposed on gestational days (gd) 6 to 15 inclusive to analytically mea...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/074823379000600308
更新日期:1990-05-01 00:00:00
abstract::In this paper, a description of olfactory anatomy is presented, followed by a brief review of modern procedures for testing olfactory function. Information from the sole study which has quantitatively examined olfactory function in patients with apparent multiple chemical sensitivity (MCS) is presented. In essence, th...
journal_title:Toxicology and industrial health
pub_type: 杂志文章,评审
doi:
更新日期:1994-07-01 00:00:00
abstract:OBJECTIVES:In this study, biological exposure indicators were used to assess the exposure of workers to cadmium (Cd), lead (Pb), manganese (Mn), and nickel (Ni) in nonferrous metal smelters. METHODS:A total of 273 male participants (178 exposed and 95 nonexposed control group), working in nonferrous metal foundries lo...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233715589262
更新日期:2016-10-01 00:00:00
abstract::In The Netherlands, risk assessment of air pollutants goes back to 1980. From 1985 onwards the risk assessment of chemicals has crystallized in a systematic multi-media approach taking into account air, water, soil, and food. Criteria Documents support the formulation of environmental quality standards. Until now, 23 ...
journal_title:Toxicology and industrial health
pub_type: 杂志文章,评审
doi:
更新日期:1990-10-01 00:00:00
abstract::Polycyclic aromatic hydrocarbons have mutagenic and carcinogenic properties and some of them are classified as probable or possible human carcinogens. Aim of this study was to evaluate the genotoxic risk in workers exposed to diesel exaust. Environmental and biological monitoring exposure to polycyclic aromatic hydroc...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233707077436
更新日期:2007-02-01 00:00:00
abstract::The effects of different methylmercury (MeHg) forms on the immune system and the hypothalamic pituitary adrenal (HPA) axis were assessed. The lymphocyte response to Concanavalin A (Con A) stimulation, blood levels of interleukin-6 (IL-6), adrenocorticotrophin hormone (ACTH), and corticosterone in the presence of diffe...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/074823379701300105
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the chemopreventive potential of organoselenium compounds (Se I and Se II) in the well-established rat model treated with 7,12-dimethylbenz[a]anthracene (DMBA), by monitoring the extent of tyrosine hydroxylase (TH) activity, adrenomedullin (ADM) level and total RNA level ...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233711432575
更新日期:2013-04-01 00:00:00
abstract::In the present work, 6 honeydew samples of known geographical and botanical origins and 11 honeybee samples were analyzed to detect possible contamination by the thermoelectric power plants in Mugla, Turkey. The contents of trace elements were determined by atomic absorption spectrometry after application of microwave...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233713503393
更新日期:2016-03-01 00:00:00
abstract::Many episodes of low back pain are disabling, thus making it one of the costly occupational health problem. The proper alignment and lifting operations during drilling process frequently exposed the oil-drilling workers to unusual strain on the spine and thus make them susceptible for developing low back pain. The pre...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233712451771
更新日期:2014-02-01 00:00:00
abstract::At the onset of the industrial age, environmental contaminants began to pose a major threat to the health of wildlife. That threat appears to continue today. In the last three decades, the focus of our concern on the health consequences of environmental pollution has been on lethal, carcinogenic, and/or extreme terato...
journal_title:Toxicology and industrial health
pub_type: 杂志文章,评审
doi:10.1177/074823379601200325
更新日期:1996-05-01 00:00:00
abstract::The aryl hydrocarbon receptor (AHR) is one of the principal xenobiotic, nuclear receptor that is responsible for the early events involved in the transcription of a complex set of genes comprising the CYP450 gene family. In the present computational study, homology modelling and molecular docking were carried out with...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233712463774
更新日期:2014-09-01 00:00:00
abstract::Needlestick and sharp instrument injuries are common in dental practice and present the risk of direct exposure to blood-borne pathogens, including hepatitis B virus. This cross-sectional study was carried out to determine the risk factors of injury and infection in three types of dental clinic in Riyadh, Saudi Arabia...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233718769553
更新日期:2018-09-01 00:00:00
abstract::The aim of the present study was to assess and compare the individual adverse effects of bisphenol A (BPA) and octylphenol (OP) on the reproductive system of prepubertal male rats. Rats were exposed to BPA and OP at doses of 125 and 250 mg/kg/day, by gavage, for 90 days. At the end of the study, the testes, epididymis...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233715603847
更新日期:2017-02-01 00:00:00
abstract::Some studies have shown that exposure to electromagnetic field (EMF) may result in structural damage to neurons. In this study, we have elucidated the alteration in the hippocampal function of offspring Wistar rats (n = 8 rats in each group) that were chronically exposed to mobile phones during their gestational perio...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233714525497
更新日期:2016-06-01 00:00:00