Are we on the threshold of a new theory of disease? Toxicant-induced loss of tolerance and its relationship to addiction and abdiction.

abstract：:Nanomaterials are widely used nowadays in a range of technological and biomedical fields. Graphene as a nanomaterial used in the health-care sector and in workplaces has raised some concerns about its toxicity. This study aimed to evaluate the cytotoxicity of graphene nanoparticles (GNPs) on the A549 epithelial cells ...

journal_title：Toxicology and industrial health

authors： Nasirzadeh N,Azari MR,Rasoulzadeh Y,Mohammadian Y

更新日期：2019-01-01 00:00:00

abstract：:The aim of the present study was to assess the influence of curcumin on liver regeneration after partial hepatectomy (PH) in rats. A total of 24 male Sprague Dawley rats were divided into three groups: sham-operated (SH), PH, and PH + curcumin; each group contains eight animals. The rats in curcumin-treated groups wer...

journal_title：Toxicology and industrial health

authors： Toydemir T,Kanter M,Erboga M,Oguz S,Erenoglu C

更新日期：2015-02-01 00:00:00

abstract：:Female Macaca fascicularis monkeys were given daily oral doses of 3.0 and 4.25 mg/kg lead, as lead nitrate, prior to breeding, and exposure was maintained throughout gestation and terminated at parturition. No overt signs of lead toxicity were observed in the maternal monkeys. The offspring were tested at 6 to 18 mont...

journal_title：Toxicology and industrial health

authors： Hopper DL,Kernan WJ,Lloyd WE

更新日期：1986-07-01 00:00:00

abstract：:In The Netherlands, risk assessment of air pollutants goes back to 1980. From 1985 onwards the risk assessment of chemicals has crystallized in a systematic multi-media approach taking into account air, water, soil, and food. Criteria Documents support the formulation of environmental quality standards. Until now, 23 ...

journal_title：Toxicology and industrial health

authors： Vermeire T,van der Heijden K

更新日期：1990-10-01 00:00:00

abstract：:This investigation used a two-source capture-recapture method (CRM) for determining ascertainment and undercounts of non-national priority listed hazardous waste sites in the states of Arizona, Maine and Pennsylvania. These findings suggest that ascertainment of hazardous waste sites vary greatly, with some more accur...

journal_title：Toxicology and industrial health

authors： Lange JH,Chang YF,LaPorte RE,Mastrangelo G

更新日期：2003-07-01 00:00:00

abstract：:Sorption of three pesticides on geologic material ranging in organic carbon content from 0.33 to 6.9 g kg-1 was measured in soil columns using a miscible displacement technique. An octanol-water partitioning model was shown to be inappropriate for predicting sorption of the less hydrophobic pesticides on the low organ...

journal_title：Toxicology and industrial health

authors： Bouchard DC,Wood AL

更新日期：1988-09-01 00:00:00

abstract：:Carvacrol (CVC), a major constituent of genera Origanum and Thymus, is such a substance that has attracted attention because of its wide variety of beneficial biological activities such as antibacterial, antifungal, and anticancer effects. However, there are limited data on the cytogenetic and antioxidant effects of C...

journal_title：Toxicology and industrial health

authors： Türkez H,Aydın E

更新日期：2016-04-01 00:00:00

abstract：:Insulin resistance (IR) is recognized as a contributory factor for a variety of liver diseases. The present study investigates the susceptibility of liver to the toxic actions of carbon tetrachloride (CCl(4)) in a rat model of IR, induced by feeding a high-fructose diet (60 g/100 g) for 30 days. A sub-lethal dose of C...

journal_title：Toxicology and industrial health

authors： Pooranaperundevi M,Sumiyabanu MS,Viswanathan P,Sundarapandiyan R,Anuradha CV

更新日期：2010-03-01 00:00:00

abstract：:The concentrations of heavy metals (cadmium (Cd), copper (Cu), nickel (Ni), lead (Pb) and zinc (Zn)) were measured in hepatopancreas and muscle of a commercial shrimp (Metapenaeus affinis), in the muscle, liver and gills of two fish species (Thryssa vitrirostris and Johnius belangerii) and in the sediment samples take...

journal_title：Toxicology and industrial health

authors： Monikh FA,Maryamabadi A,Savari A,Ghanemi K

更新日期：2015-06-01 00:00:00

abstract：:The aim of the study is to assess whether occupational exposure to urban stressors could cause alterations in urinary metanephrines levels in traffic policemen vs administrative staff of municipal police. A total of 258 subjects were included in the study: 129 traffic policemen exposed to urban stressors (68 males and...

journal_title：Toxicology and industrial health

authors： Sancini A,Tomei G,Ciarrocca M,Pimpinella B,Samperi I,Fiaschetti M,Scimitto L,Tasciotti Z,Caciari T,Tomei F

更新日期：2011-05-01 00:00:00

abstract：:Hepatocytes that were isolated from 48 hr starved rats and incubated in Krebs-Henseleit bicarbonate buffer containing 10 microM A23187, 10mM l-lactate, 1mM pyruvate and 2mM l-lysine were found to contain 0.064 mumol of inorganic pyrophosphate/g wet wgt cells. Addition of either 20mM acetate or butyrate, which caused t...

journal_title：Toxicology and industrial health

authors： Gitomer WL,Veech RL

更新日期：1986-09-01 00:00:00

abstract：:The hypolipidemic effect of 10% fruit fibers in rats fed with high-fat diet (HFD) was evaluated. This study was conducted on a total of 50 male Albino rats divided into 10 equal groups fed with different types of dietary fruits. The feeding period lasted for 24 weeks. Fasting blood samples were collected and sera sepa...

journal_title：Toxicology and industrial health

authors： Esmael OA,Sonbul SN,Kumosani TA,Moselhy SS

更新日期：2015-03-01 00:00:00

abstract：:The Agency for Toxic Substances and Disease Registry (ATSDR) prepared this health consultation to provide support for assessing the public health implications of hazardous chemical exposure, primarily through drinking water, related to releases of chromated copper arsenate (CCA) in the port of Djibouti. CCA from a shi...

journal_title：Toxicology and industrial health

authors： Chou S,Colman J,Tylenda C,De Rosa C

更新日期：2007-05-01 00:00:00

abstract：:Adult female Swiss Webster and B6C3F1 mice received distilled water only or water containing 0.1, 1.0, 10, 100 or 1000 ppb of aldicarb daily for 34 days. The target concentration of aldicarb present in the 10 ppb dosing solution was analytically verified on a daily basis as was its stability over a 48-hr period. To de...

journal_title：Toxicology and industrial health

authors： Thomas PT,Ratajczak HV

更新日期：1988-09-01 00:00:00

abstract：:Cisplatin (CP) is a widely used anticancer drug; however, it has several side effects such as nephrotoxicity. Ginger, the rhizome of Zingiber officinale, consumed since ancient times has numerous health benefits. The objective of this work was to evaluate the protective effect of ginger extract (GE) against CP-induced...

journal_title：Toxicology and industrial health

authors： Ali DA,Abdeen AM,Ismail MF,Mostafa MA

更新日期：2015-10-01 00:00:00

abstract：:The aim of this study was to evaluate the antiapoptotic and proliferative activity of curcumin (Cur) on the ovarian follicles in mice exposed to whole body ionizing radiation (Rd). The mice were exposed to 8.3 gray whole body Rd, and Cur groups were given as a daily dose of 100 mg/kg of Cur for 10 days (10 days before...

journal_title：Toxicology and industrial health

authors： Aktas C,Kanter M,Kocak Z

更新日期：2012-10-01 00:00:00

abstract：:It has been found that exposure to manganese (Mn) could induce reproductive dysfunction, but its occupational risk in male workers is unclear. This study aims to assess the association of occupational Mn exposure with reproductive hormones and semen quality in a cross-sectional study. Urinary Mn, semen quality, and re...

journal_title：Toxicology and industrial health

authors： Yang H,Wang J,Yang X,Wu F,Qi Z,Xu B,Liu W,Deng Y

更新日期：2019-01-01 00:00:00

abstract：:Elaeagnus angustifolia was analyzed for determination of metals, phytoconstituents, bactericidal, fungicidal and insecticidal effects and to explore its chemical and biological potential. The root, branches, leaves, stem bark and root bark parts of E. angustifolia were found to contain iron, lead, copper, cadmium, zin...

journal_title：Toxicology and industrial health

authors： Khan SU,Khan AU,Shah AU,Shah SM,Hussain S,Ayaz M,Ayaz S

更新日期：2016-01-01 00:00:00

abstract：:Pyrrolizidine alkaloid isoline is isolated from the traditional Chinese medicine Ligularia duciformis. Our previous reports have already demonstrated isoline-induced liver injury in mice. The present study is designed to observe the involvement of intracellular reduced glutathione (GSH) in isoline-induced cytotoxicity...

journal_title：Toxicology and industrial health

authors： Chen Y,Ji L,Xiong A,Yang L,Wang Z

更新日期：2013-07-01 00:00:00

abstract：:The New York State Angler Study will evaluate the association between past and current consumption of contaminated fish from Lake Ontario and both short- and long-term health effects in a population-based cohort. It will measure fish consumption and reproductive and developmental health among 10,518 male anglers and 6...

journal_title：Toxicology and industrial health

authors： Vena JE,Buck GM,Kostyniak P,Mendola P,Fitzgerald E,Sever L,Freudenheim J,Greizerstein H,Zielezny M,McReynolds J,Olson J

更新日期：1996-05-01 00:00:00

abstract：:The objective is to present historical asbestos airborne concentrations associated with activities involving presumably asbestos-containing materials in steel mills. A total of 138 historical industrial hygiene air samples collected in three US steel mills from 1972 to 1982 were analyzed. The majority of samples were ...

journal_title：Toxicology and industrial health

authors： Hollins D,Burns A,Unice K,Paustenbach DJ

更新日期：2019-11-01 00:00:00

abstract：:This study focuses on investigating the possible protective effect of sodium selenite (Na2SeO3) and/or vitamin E against mercuric chloride (HgCl2)-induced hepatotoxicity in rat. Male rats were given HgCl2 (1 mg/kg body weight (bw)) and HgCl2 plus Na2SeO3 (0.25 mg/kg bw) and/or vitamin E (100 mg/kg bw) daily via gavage...

journal_title：Toxicology and industrial health

authors： Uzunhisarcikli M,Aslanturk A,Kalender S,Apaydin FG,Bas H

更新日期：2016-09-01 00:00:00

abstract：:Organophosphate poisoning is a life-threatening condition, which is being responsible for the symptoms due to cholinergic effects. Clinical status and blood levels of cholinesterase are used its diagnosis. While atropine and pralidoxime (PAM) appear as essential medications, hemofiltration treatments and lipid solutio...

journal_title：Toxicology and industrial health

authors： Karakus A,Celik MM,Karcioglu M,Tuzcu K,Erden ES,Zeren C

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:For several decades, there has been increasing evidence for excess incidence of lung cancer among workers in the rubber industry. The purpose of this study was to assess the risk of lung cancer occurrence among Egyptian workers involved in the rubber industry using two circulating protein biomarkers. METHODS...

journal_title：Toxicology and industrial health

authors： Mourad BH

更新日期：2020-04-01 00:00:00

abstract：:Acrylamide has been discovered in foods cooked at high temperature. A potentially harmful effect of this dietary component has been suggested by data indicating its association with increased breast cancer. This study investigated the potential effects of acrylamide in nontumorigenic breast cells by assessing expressi...

journal_title：Toxicology and industrial health

authors： Lyn-Cook LE Jr,Tareke E,Word B,Starlard-Davenport A,Lyn-Cook BD,Hammons GJ

更新日期：2011-02-01 00:00:00

abstract：:As part of its mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) prepares toxicological profiles on hazardous chemicals found at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) National Priorities List (NPL) sites that have the greatest public health impact. These pro...

journal_title：Toxicology and industrial health

authors： Wilbur S,Wohlers D,Paikoff S,Keith LS,Faroon O

更新日期：2008-06-01 00:00:00

abstract：:Atmospheric acid precursor emissions in Asia are increasing at a significant rate. This is expected to continue for the next several years. This main purpose for this study is to observe the concentration variations of PM(2.5), PM(2.5-10), PM(10), total suspended particulates (TSP), atmospheric particulates, and dry d...

journal_title：Toxicology and industrial health

authors： Fang GC,Liu CK

更新日期：2010-10-01 00:00:00

abstract：:This study aimed to evaluate the extrapulmonary effects of exposure to cigarette smoke (CS) through the analysis of blood components and histopathological examinations of the trachea and diaphragm muscle (DM) in C57BL/6 mice. Thirty-six animals were exposed to six cigarettes per day for 5 days. The mice were divided i...

journal_title：Toxicology and industrial health

authors： Martins TL,Campos KKD,Araújo NPDS,Machado DF,Bezerra FS

更新日期：2017-09-01 00:00:00

abstract：:Retinyl esters are the storage form of vitamin A in skin, and retinyl palmitate (RP) accounts for the majority of the retinyl esters endogenously formed in skin. RP is also obtained exogenously through the topical application of cosmetic and skin care products that contain RP. There is limited information on the penet...

journal_title：Toxicology and industrial health

authors： Yan J,Wamer WG,Howard PC,Boudreau MD,Fu PP

更新日期：2006-05-01 00:00:00

abstract：:Pesticides are omnipresent in environment, water, fruits, and vegetables and are considered as risk factors for human health. Consumers are mainly exposed to pesticides through diet, and the main question to be answered concerns the impact of such exposure on health. In this study, we developed a mouse model to mimic ...

journal_title：Toxicology and industrial health

authors： Mansour SA,Gamet-Payrastre L

更新日期：2016-07-01 00:00:00