Investigation of cytotoxic, genotoxic and oxidative properties of carvacrol in human blood cells.

abstract：:People live in the mountains distributed across the world and are exposed to reduced inspired oxygen and lower barometric pressure along with other factors that lead to high-altitude diseases. The present study was conducted to examine what extent of marketed medicines used in the management of high-altitude sickness ...

journal_title：Toxicology and industrial health

authors： Ghosh M,Biswas D,Mukherjee A

更新日期：2010-08-01 00:00:00

abstract：:Polycyclic aromatic hydrocarbons have mutagenic and carcinogenic properties and some of them are classified as probable or possible human carcinogens. Aim of this study was to evaluate the genotoxic risk in workers exposed to diesel exaust. Environmental and biological monitoring exposure to polycyclic aromatic hydroc...

journal_title：Toxicology and industrial health

authors： Maina G,Manzari M,Palmas A,Passini V,Filon FL

更新日期：2007-02-01 00:00:00

abstract：:Some studies have shown that exposure to electromagnetic field (EMF) may result in structural damage to neurons. In this study, we have elucidated the alteration in the hippocampal function of offspring Wistar rats (n = 8 rats in each group) that were chronically exposed to mobile phones during their gestational perio...

journal_title：Toxicology and industrial health

authors： Razavinasab M,Moazzami K,Shabani M

更新日期：2016-06-01 00:00:00

abstract：:The aim of this study was to investigate the effect of oral cadmium (Cd) intoxication on the antioxidant response and its relationship with essential bioelements like copper (Cu) and zinc (Zn). The experimental group was chronically exposed to Cd daily for 8 weeks via consumption of water containing 15 ppm cadmium chl...

journal_title：Toxicology and industrial health

authors： Erdem O,Yazihan N,Kocak MK,Sayal A,Akcil E

更新日期：2016-08-01 00:00:00

abstract：:This investigation used a two-source capture-recapture method (CRM) for determining ascertainment and undercounts of non-national priority listed hazardous waste sites in the states of Arizona, Maine and Pennsylvania. These findings suggest that ascertainment of hazardous waste sites vary greatly, with some more accur...

journal_title：Toxicology and industrial health

authors： Lange JH,Chang YF,LaPorte RE,Mastrangelo G

更新日期：2003-07-01 00:00:00

abstract：:Tris(2-chloroethyl)phosphate (TRCP), a flame-retardant plasticizer used in plastics, polymeric foams and synthetic fibers, was studied as part of the National Toxicology Program's class study of phosphate flame-retardants. TRCP was administered at 0, 22, 44, 88, 175 and 350 mg/kg to both sexes of rats and 0, 44, 88, 1...

journal_title：Toxicology and industrial health

authors： Matthews HB,Dixon D,Herr DW,Tilson H

更新日期：1990-01-01 00:00:00

abstract：:This report reviews the literature on the impact of exposure to trichloroethylene (TCE) on human health. Special emphasis is given to the health effects reported in excess of national norms by participants in the TCE Subregistry of the Volatile Organic Compounds Registry of the National Exposure Registries--persons wi...

journal_title：Toxicology and industrial health

authors： Gist GL,Burg JR

更新日期：1995-05-01 00:00:00

abstract：:Acetaminophen (APAP) is widely used in the treatment of pain. Toxic doses of APAP cause acute liver failure, but therapeutic doses are believed to be safe. The purpose of this study is to investigate the effects of administration of subtoxic doses of APAP on liver and blood levels of insulin-like growth factor-1 (IGF-...

journal_title：Toxicology and industrial health

authors： Ozdemir D,Aksu I,Baykara B,Ates M,Sisman AR,Kiray M,Buyuk A,Uysal N

更新日期：2016-01-01 00:00:00

abstract：:The aryl hydrocarbon receptor (AHR) is one of the principal xenobiotic, nuclear receptor that is responsible for the early events involved in the transcription of a complex set of genes comprising the CYP450 gene family. In the present computational study, homology modelling and molecular docking were carried out with...

journal_title：Toxicology and industrial health

authors： Panda R,Cleave AS,Suresh PK

更新日期：2014-09-01 00:00:00

abstract：:Trivalent chromium (Cr) is an environmental contaminant, which is extensively used in tanning industries throughout the world and causes various forms of health hazards in tannery workers. Therefore, a cross-sectional study design was used to evaluate the DNA damage and oxidative stress condition in tannery workers ex...

journal_title：Toxicology and industrial health

authors： Ambreen K,Khan FH,Bhadauria S,Kumar S

更新日期：2014-06-01 00:00:00

abstract：:The effects of trona (Kaun), a food additive, on the redox status of the liver and kidney of male Wistar rats were investigated. A total of 60 male rats (145 ± 2.52 g) were grouped into four: A, B, C and D, where group A (the control) received 1 mL of distilled water orally while those in groups B, C and D (test group...

journal_title：Toxicology and industrial health

authors： Ajiboye TO,Komolafe YO,Yakubu MT,Ogunbode SM

更新日期：2015-02-01 00:00:00

abstract：:Zinc oxide nanoparticles (ZnO NPs) are important nanomaterials with myriad applications and in widespread use. The main aim of this study was to evaluate the direct effect of ZnO NPs on steroidogenesis by considering mouse testicular Leydig cells (TM3) as an in vitro model system. The uptake, intracellular behaviour, ...

journal_title：Toxicology and industrial health

authors： Bara N,Kaul G

更新日期：2018-08-01 00:00:00

abstract：:Exposure to the humidifier disinfectant, polyhexamethylene guanidine phosphate (PHMG), in mists generated from ultrasonic humidifiers was studied in a simulation chamber and apartment rooms. PHMG is suspected as a causative agent of lung disease in Korea residences. In the simulation-chamber study, the amount of disin...

journal_title：Toxicology and industrial health

authors： Lee JH,Yu IJ

更新日期：2017-11-01 00:00:00

abstract：:Needlestick and sharp instrument injuries are common in dental practice and present the risk of direct exposure to blood-borne pathogens, including hepatitis B virus. This cross-sectional study was carried out to determine the risk factors of injury and infection in three types of dental clinic in Riyadh, Saudi Arabia...

journal_title：Toxicology and industrial health

authors： Al-Zoughool M,Al-Shehri Z

更新日期：2018-09-01 00:00:00

abstract：:Adult female Swiss Webster and B6C3F1 mice received distilled water only or water containing 0.1, 1.0, 10, 100 or 1000 ppb of aldicarb daily for 34 days. The target concentration of aldicarb present in the 10 ppb dosing solution was analytically verified on a daily basis as was its stability over a 48-hr period. To de...

journal_title：Toxicology and industrial health

authors： Thomas PT,Ratajczak HV

更新日期：1988-09-01 00:00:00

abstract：:Aflatoxin B1 (AFB1) is a toxic compound commonly found as a contaminant in human food. It is carcinogenic due its potential in inducing the oxidative stress and distortion of the most antioxidant enzymes. Since black tea possesses strong antioxidant activity, it protects cells and tissues against oxidative stress. Cur...

journal_title：Toxicology and industrial health

authors： Alm-Eldeen AA,Mona MH,Shati AA,El-Mekkawy HI

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:Polycyclic aromatic hydrocarbons (PAHs) are potent environmental pollutants. Benzo[α]pyrene (B[α]P) is the major compound of PAHs that acts by activating aryl hydrocarbon receptor (AhR) in cells. B[α]P is a known carcinogen and an immunotoxicant; however, its role with regard to nuclear factor of activated T ...

journal_title：Toxicology and industrial health

authors： Parsa M,Ostad SN,Moogahi SM,Bayat M,Ghahremani MH

更新日期：2016-07-01 00:00:00

abstract：:The actual stage of the development of Kosovo is characterized by the concerning levels of environmental pollution and the serious health problems attributed to the emission of pollutants into air, soil and water. In this context, river pollution is one of the main threats due to the discharge of untreated urban and i...

journal_title：Toxicology and industrial health

authors： Alija AJ,Bresgen N,Bojaxhi E,Krenn M,Bajraktari ID,Eckl PM

更新日期：2018-08-01 00:00:00

abstract：:Within hours after the terrorist attack on the Pentagon on September 11, 2001, an extensive sampling effort was initiated within the building to include surface wipe sampling for select coplanar polychlorinated biphenyls (PCBs), congeners of polychlorinated dibenzo(p)dioxins and dibenzofurans (dioxins/furans) and lead...

journal_title：Toxicology and industrial health

authors： Gaborek BJ,Mullikin JM,Pitrat AT,Cummings L,May LM

更新日期：2001-06-01 00:00:00

abstract：:Paraphenylene diamine (PPD) hair dye poisoning is a common health problem in the Middle East and Indian subcontinent. It is the most common cause of suicide intent especially among females. We hereby present a 27-year-old female who presented with a clinical feature of PPD poisoning due to a suicidal attempt, and she ...

journal_title：Toxicology and industrial health

authors： Abdelraheem MB,Elbushra M,Ali el-T,Ellidir RA,Bushara AI,Abdelraheem WB,Zijlstra EE

更新日期：2014-09-01 00:00:00

abstract：:Previous cross-sectional studies have shown that exposure to cleaning chemicals among health-care workers (HCWs) is associated with respiratory disorders and ventilatory function changes. This study aimed to further explore this association using a longitudinal approach. A prospective 2-year follow-up study was carrie...

journal_title：Toxicology and industrial health

authors： El-Helaly M,Balkhy HH,Waseem K,Khawaja S

更新日期：2016-12-01 00:00:00

abstract：:The aim of this study was to investigate the different testicular toxicity and the role of apoptosis in the possible mechanism induced by the two isomers of bromopropanes (BPs) in the same dosage. Following the 14-day treatment with a single dose of 1-BP and 2-BP (1 g/kg), male rats were killed and a series of experim...

journal_title：Toxicology and industrial health

authors： Xin QQ,Yong Huang,Jie Li,Zhang WJ,Tao Yu,Hua Wang,Cheng Zhang,Ye DQ,Fen Huang

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the chemopreventive potential of organoselenium compounds (Se I and Se II) in the well-established rat model treated with 7,12-dimethylbenz[a]anthracene (DMBA), by monitoring the extent of tyrosine hydroxylase (TH) activity, adrenomedullin (ADM) level and total RNA level ...

journal_title：Toxicology and industrial health

authors： Talas ZS,Ozdemir I,Ates B,Gok Y,Yilmaz I

更新日期：2013-04-01 00:00:00

abstract：:Organophosphate (OP) compounds are the most commonly used pesticide groups and they are commercially used in the market for local and industrial purposes. Paraoxonase 1 (PON1) enzyme plays an important role in biotransformation of OP compounds, which shows toxic effects via inhibiting the acetylcholinesterase (AChE). ...

journal_title：Toxicology and industrial health

authors： Sunay SZ,Kayaaltı Z,Bayrak T,Söylemezoğlu T

更新日期：2015-12-01 00:00:00

abstract：:Exposure to inhalation anesthetics (IAs) has been associated with DNA damage as reflected in the increased frequency of micronuclei (MN) and chromosomal aberrations (CAs). The present study was undertaken to ascertain whether there was any correlation between increased MN and CA and the extent of oxidative stress as w...

journal_title：Toxicology and industrial health

authors： Neghab M,Kargar-Shouroki F,Mozdarani H,Yousefinejad S,Alipour H,Fardid R

更新日期：2020-06-01 00:00:00

abstract：:Metalworking fluids (MWFs) are complex formulations designed for effective lubricating, cooling, and cleaning tools and parts during machining operations. Adverse health effects such as respiratory symptoms, dermatitis, and cancer have been reported in workers exposed to MWFs. Several constituents of MWFs have been im...

journal_title：Toxicology and industrial health

authors： Ryan KR,Cesta MF,Herbert R,Brix A,Cora M,Witt K,Kissling G,Morgan DL

更新日期：2017-05-01 00:00:00

abstract：STUDY OBJECTIVES:Asbestos bodies (ABs) form as asbestos fibers become coated by a cellular iron- and protein-rich matrix. ABs have been reported in lymph nodes and a few extrapulmonary sites, but no data exist as to their formation outside of the lung. It is not clear whether the AB found in these extrapulmonary areas ...

journal_title：Toxicology and industrial health

authors： Williams MG,Dodson RF,Dickson EW,Fraire AE

更新日期：2001-02-01 00:00:00

abstract：:The current study explores the effects of the inhalation of lead (Pb), Cd and its mixture (Pb-Cd) in a mice model, analysing metal concentrations in the lung, and the morphological modifications in the bronchiolar epithelium identified by scanning electron microscopy after eight weeks of inhalation. Our results indica...

journal_title：Toxicology and industrial health

authors： Fortoul TI,Avila-Costa MR,Espejel-Maya G,Mussali-Galante P,Avila-Casado Mdel C,Hernández-Serrato MI,Saldivar-Osorio L

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVES:Various authors who studied the effects of aluminium (Al) exposure on the neurocognitive system in the last 30 years have reached different and often contradictory conclusions. The aim of this study is to help clarify the effects that the metal causes on cognitive ability in a group of naval welders exposed ...

journal_title：Toxicology and industrial health

authors： Giorgianni CM,D'Arrigo G,Brecciaroli R,Abbate A,Spatari G,Tringali MA,Gangemi S,De Luca A

更新日期：2014-05-01 00:00:00

abstract：:Brominated flame retardants (BFRs) and heavy metals (HMs) are two main types of pollutants in electronic waste recycling sites, which are also ubiquitously detectable in environmental media and human tissues. However, the adverse health effects of exposure to the mixture of these types of pollutants are unknown. In th...

journal_title：Toxicology and industrial health

authors： Chen J,Ma X,Tian L,Kong A,Wang N,Huang C,Yang D

更新日期：2018-09-01 00:00:00