Assessment of carbamate pesticide immunotoxicity.

abstract：:As one of the main components of risk assessment, exposure assessment plays a key role in evaluating risk. Many different scenarios can be developed to estimate the risk from exposure to chemicals such as persistent organic pollutants (POPs). The US Food and Drug Administration (FDA)'s Center for Food Safety and Appli...

journal_title：Toxicology and industrial health

authors： Jensen E,Egan S,Canady R,Bolger P

更新日期：2001-06-01 00:00:00

abstract：:The negative health effects caused by lead (Pb) exposure are widely recognized; however, the molecular mechanisms remain unknown. The aim of this study was to assess the effect of occupational Pb exposure on telomere length and to investigate the potential mechanisms leading to telomere shortening. A cohort of 334 mal...

journal_title：Toxicology and industrial health

authors： Pawlas N,Płachetka A,Kozłowska A,Mikołajczyk A,Kasperczyk A,Dobrakowski M,Kasperczyk S

更新日期：2016-12-01 00:00:00

abstract：:The current study explores the effects of the inhalation of lead (Pb), Cd and its mixture (Pb-Cd) in a mice model, analysing metal concentrations in the lung, and the morphological modifications in the bronchiolar epithelium identified by scanning electron microscopy after eight weeks of inhalation. Our results indica...

journal_title：Toxicology and industrial health

authors： Fortoul TI,Avila-Costa MR,Espejel-Maya G,Mussali-Galante P,Avila-Casado Mdel C,Hernández-Serrato MI,Saldivar-Osorio L

更新日期：2004-06-01 00:00:00

abstract：:Oxidative stress is accepted as a potential responsible mechanism in the pathogenesis of radiocontrast media (RCM)-induced hepatotoxicity. Therefore, we aimed to investigate the protective effects of ebselen against RCM-induced hepatotoxicity by measuring tissue oxidant/antioxidant parameters and histological changes ...

journal_title：Toxicology and industrial health

authors： Basarslan F,Yilmaz N,Davarci I,Akin M,Ozgur M,Yilmaz C,Ulutas KT

更新日期：2013-09-01 00:00:00

abstract：:Paraphenylene diamine (PPD) hair dye poisoning is a common health problem in the Middle East and Indian subcontinent. It is the most common cause of suicide intent especially among females. We hereby present a 27-year-old female who presented with a clinical feature of PPD poisoning due to a suicidal attempt, and she ...

journal_title：Toxicology and industrial health

authors： Abdelraheem MB,Elbushra M,Ali el-T,Ellidir RA,Bushara AI,Abdelraheem WB,Zijlstra EE

更新日期：2014-09-01 00:00:00

abstract：:People live in the mountains distributed across the world and are exposed to reduced inspired oxygen and lower barometric pressure along with other factors that lead to high-altitude diseases. The present study was conducted to examine what extent of marketed medicines used in the management of high-altitude sickness ...

journal_title：Toxicology and industrial health

authors： Ghosh M,Biswas D,Mukherjee A

更新日期：2010-08-01 00:00:00

abstract：:Lead is a heavy metal that affects various systems and organs in the body, especially the nervous system. In this study, the in vivo and in vitro effects of lead on neurons were analyzed. We divided mouse pups into three groups based on the concentration of lead exposure: the control group, the low-dose group, and the...

journal_title：Toxicology and industrial health

authors： Duan Y,Peng L,Shi H,Jiang Y

更新日期：2017-11-01 00:00:00

abstract：:A comparative potency method for cancer risk assessment has been developed based on a constant relative potency hypothesis. This method was developed and tested using data from a battery of short-term mutagenesis bioassays, animal tumorigenicity data and human lung cancer risk estimations. This data base was developed...

journal_title：Toxicology and industrial health

authors： Lewtas J

更新日期：1985-12-01 00:00:00

abstract：:The aim of this study was to investigate the different testicular toxicity and the role of apoptosis in the possible mechanism induced by the two isomers of bromopropanes (BPs) in the same dosage. Following the 14-day treatment with a single dose of 1-BP and 2-BP (1 g/kg), male rats were killed and a series of experim...

journal_title：Toxicology and industrial health

authors： Xin QQ,Yong Huang,Jie Li,Zhang WJ,Tao Yu,Hua Wang,Cheng Zhang,Ye DQ,Fen Huang

更新日期：2010-09-01 00:00:00

abstract：:Excessive exposure to nickel may cause health effects on the blood, lung, nose, kidney, reproductive system, skin and the unborn child. In the present study, we found that Ni²⁺ exposure led to a time- and dose-dependent proliferation arrest and death in human leukemia HL-60 cells. In the presence of 1 mM Ni²⁺, reactiv...

journal_title：Toxicology and industrial health

authors： Chen J,Han J,Wang J

更新日期：2013-05-01 00:00:00

abstract：:Mercury has been used in many domains of human activities for many years, although in any form mercury is reported to be toxic. On the other hand, lichens have been used in the treatment of several diseases such as tuberculosis, hemorrhoids, ulcer, dysentery and cancer. Animal investigations on some common lichen spec...

journal_title：Toxicology and industrial health

authors： Turkez H,Dirican E

更新日期：2012-02-01 00:00:00

abstract：:This study was realized to investigate the possible beneficial effect of thymoquinone (TQ), the major active component of volatile oil of Nigella sativa seeds, against lead (Pb)-induced inhibition of rat testicular functions. Adult rats were randomized into four groups: a control group receiving no treatment; a Pb gro...

journal_title：Toxicology and industrial health

authors： Mabrouk A,Ben Cheikh H

更新日期：2016-06-01 00:00:00

abstract：:Maneb is a dithiocarbamate fungicide that contains manganese. Dithiocarbamates are considered to be chemicals of low toxicity. An experimental group (n = 10) received maneb (obtained from Hoecht-Shering) at a concentration of 250 ppm in distilled water five days a week (treatment time is three weeks). It was orally ad...

journal_title：Toxicology and industrial health

authors： Deveci E

更新日期：2006-10-01 00:00:00

abstract：:Chronic exposure to jet fuel has been shown to have adverse effects on human liver function, to cause emotional dysfunction, to cause abnormal electroencephalograms, to cause shortened attention spans, and to decrease sensorimotor speed. Due to the decision by the United States Air Force to implement the widespread us...

journal_title：Toxicology and industrial health

authors： Harris DT,Sakiestewa D,Robledo RF,Witten M

更新日期：1997-09-01 00:00:00

abstract：:In summary, we have described our method of treating phosgene inhalation injury. We have presented two serious cases in detail which demonstrate that survival was associated with aggressive therapy. Several points should be mentioned. The pulmonary edema and resulting fluid and foam production can be so copious as to ...

journal_title：Toxicology and industrial health

authors： Regan RA

更新日期：1985-10-01 00:00:00

abstract：:Zinc oxide nanoparticles (ZnONP) are manufactured on a large scale and can be found in a variety of consumer products, such as sunscreens, lotions, paints and food additives. Few studies have been carried out on its genotoxic potential and related mechanisms in whole organisms. In the present study, the in vivo genoto...

journal_title：Toxicology and industrial health

authors： Carmona ER,Inostroza-Blancheteau C,Rubio L,Marcos R

更新日期：2016-12-01 00:00:00

abstract：:Recently, we have detailed a DNA alkaline unwinding assay (DAUA) that can be used to rapidly measure chemically induced strand breaks in mammalian cells (Daniel et al., 1985). In this paper we present further development of this assay, including: (1) studies on the relationship between DNA adducts and DNA strand break...

journal_title：Toxicology and industrial health

authors： Daniel FB,Chang LW,Schenck KM,DeAngelo AB,Skelly MF

更新日期：1989-10-01 00:00:00

abstract：:The hypolipidemic effect of 10% fruit fibers in rats fed with high-fat diet (HFD) was evaluated. This study was conducted on a total of 50 male Albino rats divided into 10 equal groups fed with different types of dietary fruits. The feeding period lasted for 24 weeks. Fasting blood samples were collected and sera sepa...

journal_title：Toxicology and industrial health

authors： Esmael OA,Sonbul SN,Kumosani TA,Moselhy SS

更新日期：2015-03-01 00:00:00

abstract：:Silver nanoparticles (Ag NPs) are widely used in nanomedicine, pharmaceutical products, industry and other consumer products owing to their unique physiochemical properties with probable potential risk to human health and the ecosystems. The aim of this work was to investigate the in-life morphological effects, bioche...

journal_title：Toxicology and industrial health

authors： Al-Doaiss AA,Jarrar Q,Alshehri M,Jarrar B

更新日期：2020-08-01 00:00:00

abstract：:We recently determined that the metabolism of a series of tumorigenic pyrrolizidine alkaloids resulted in the formation of a set of 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine (DHP)-derived DNA adducts. These DHP-derived DNA adducts have been proposed as potential biomarkers of pyrrolizidine alkaloid tumorige...

journal_title：Toxicology and industrial health

authors： Chou MW,Fu PP

更新日期：2006-09-01 00:00:00

abstract：:Several classes of environmental contaminants have been claimed or suggested to possess endocrine-disrupting potency, which may result in reproductive problems and developmental disorders. In this paper the focus is on the multiple and interactive mechanisms of interference of persistent polyhalogenated aromatic hydro...

journal_title：Toxicology and industrial health

authors： Brouwer A,Morse DC,Lans MC,Schuur AG,Murk AJ,Klasson-Wehler E,Bergman A,Visser TJ

更新日期：1998-01-01 00:00:00

abstract：:In this study, we investigated the protective effect of pentoxifilline (PTX) on smoking-induced damage in rat kidney tissues. Twenty-seven male Wistar rats were used in the study. Animals were divided into three equal groups as follows: Group 1: control group with only normal saline (NS; 0.9% NaCl) injection for 8 wee...

journal_title：Toxicology and industrial health

authors： Ozkurkcugil C,Yilmaz MY,Ozkan L,Kokturk S,Isken T

更新日期：2011-05-01 00:00:00

abstract：INTRODUCTION:Spirometry is the main pulmonary function test routinely employed in the occupational medicine practice. Its interpretation depends on the choice of the theoretical reference values. Therefore, our objective was to retrospectively evaluate the differences in the spirometric interpretation according to the ...

journal_title：Toxicology and industrial health

authors： Cioffi DL,Leso V,Carbone U,Iavicoli I

更新日期：2020-02-01 00:00:00

abstract：:The New York State Angler Study will evaluate the association between past and current consumption of contaminated fish from Lake Ontario and both short- and long-term health effects in a population-based cohort. It will measure fish consumption and reproductive and developmental health among 10,518 male anglers and 6...

journal_title：Toxicology and industrial health

authors： Vena JE,Buck GM,Kostyniak P,Mendola P,Fitzgerald E,Sever L,Freudenheim J,Greizerstein H,Zielezny M,McReynolds J,Olson J

更新日期：1996-05-01 00:00:00

abstract：:In the framework of a series of experiments conducted to evaluate the carcinogenic effects of oxygenated gasoline additives, MTBE was analyzed in an oral lifetime carcinogenicity study using 8-week-old male and female Sprague-Dawley rats. These experiments were part of a large research project on gasoline carcinogenic...

journal_title：Toxicology and industrial health

authors： Belpoggi F,Soffritti M,Maltoni C

更新日期：1995-03-01 00:00:00

abstract：:Arsenic poisoning is well-known for its innumerable toxic and carcinogenic effects. In vivo data on reproductive toxicity are also known but in vitro data are scant. Presently, we evaluated the in vitro toxic effects of sodium arsenite (NaAsO2) on adult mice testes and epididymal tissues using organ cultures. Testicul...

journal_title：Toxicology and industrial health

authors： Anwar N,Qureshi IZ

更新日期：2019-10-01 00:00:00

abstract：:This investigation gives detailed analysis of peripheral marker enzymes as well as neurobehavioral tests following chronic aluminium (Al) exposure (10 mg/kg b.w. for 12 weeks intragastrically). We observed a significant decrease in the levels of serum cholinesterase after toxicity. The enzymatic activity of cytochrome...

journal_title：Toxicology and industrial health

authors： Kaur A,Gill KD

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:Polycyclic aromatic hydrocarbons (PAHs) are potent environmental pollutants. Benzo[α]pyrene (B[α]P) is the major compound of PAHs that acts by activating aryl hydrocarbon receptor (AhR) in cells. B[α]P is a known carcinogen and an immunotoxicant; however, its role with regard to nuclear factor of activated T ...

journal_title：Toxicology and industrial health

authors： Parsa M,Ostad SN,Moogahi SM,Bayat M,Ghahremani MH

更新日期：2016-07-01 00:00:00

abstract：:This study on the effect of genetically modified (GM) and non-GM canola on soybean was carried out for physiological and biochemical biosafety assessment of GM canola. Methanolic extracts of GM and non-GM canola were assessed on seed germination and growth of soybean (Glycine max L.) under sterilized conditions. The e...

journal_title：Toxicology and industrial health

authors： Syed K,Shinwari ZK

更新日期：2016-03-01 00:00:00

abstract：:This paper describes the development and implementation of physiologically-based pharmacokinetic (PB-Pk) models to examine the disposition of xenobiotics and their bioactivation. In a PB-Pk model, the structure of the model is based, to as great extent as practicable, on the actual physiological and biochemical struct...

journal_title：Toxicology and industrial health

authors： Clewell HJ 3rd,Andersen ME

更新日期：1994-01-01 00:00:00