The New York Angler Cohort Study: exposure characterization and reproductive and developmental health.

Abstract:

:The New York State Angler Study will evaluate the association between past and current consumption of contaminated fish from Lake Ontario and both short- and long-term health effects in a population-based cohort. It will measure fish consumption and reproductive and developmental health among 10,518 male anglers and 6,651 of their wives or partners, as well as among 913 female anglers. To characterize exposure among subgroups of the cohort, further analytical methods were developed and implemented to measure specific polychlorinated biphenyls (PCB) congeners, methylmercury, and other substances in biological samples. Exposure assessment has been completed for a stratified random sample of 321 anglers. In addition, analyses for 79 congeners of PCBs are complete for 177 anglers. A special study of duck and turtle consumers currently is underway. Telephone interviews have been completed with 2,454 of the 2,999 women who planned a pregnancy between 1991 and 1994. The entire cohort of male anglers, partners of male anglers, and female anglers has been submitted for matching with the New York State live birth and fetal death registries to obtain lifetime reproductive histories. A medical record abstraction study will assess perinatal and developmental outcomes among the 3,442 births that occurred between 1986 and 1991. Finally, a study of breast milk from currently lactating women is underway, and 215 breast milk samples have been collected from the planned pregnancy subcohort. Progress on each of the study components is discussed herein.

journal_name

Toxicol Ind Health

authors

Vena JE,Buck GM,Kostyniak P,Mendola P,Fitzgerald E,Sever L,Freudenheim J,Greizerstein H,Zielezny M,McReynolds J,Olson J

doi

10.1177/074823379601200305

subject

Has Abstract

pub_date

1996-05-01 00:00:00

pages

327-34

issue

3-4

eissn

0748-2337

issn

1477-0393

journal_volume

12

pub_type

杂志文章
  • River pollution in the Kosovo: Cyto- and genotoxic effects of water samples in the primary rat hepatocyte assay.

    abstract::The actual stage of the development of Kosovo is characterized by the concerning levels of environmental pollution and the serious health problems attributed to the emission of pollutants into air, soil and water. In this context, river pollution is one of the main threats due to the discharge of untreated urban and i...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233718773027

    authors: Alija AJ,Bresgen N,Bojaxhi E,Krenn M,Bajraktari ID,Eckl PM

    更新日期:2018-08-01 00:00:00

  • Pycnogenol in cigarette filters scavenges free radicals and reduces mutagenicity and toxicity of tobacco smoke in vivo.

    abstract::Despite large-scale anti-smoking campaigns throughout the world, the number of smokers remains high and cigarette smoking continues to represent a life-threatening health risk. Until a smoke-free society is achieved, reduction of cigarette smoke toxins may reduce the health burden. Current cigarette filter techniques ...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1191/0748233702th145oa

    authors: Zhang D,Tao Y,Gao J,Zhang C,Wan S,Chen Y,Huang X,Sun X,Duan S,Schönlau F,Rohdewald P,Zhao B

    更新日期:2002-06-01 00:00:00

  • High-altitude medicines: a short-term genotoxicity study.

    abstract::People live in the mountains distributed across the world and are exposed to reduced inspired oxygen and lower barometric pressure along with other factors that lead to high-altitude diseases. The present study was conducted to examine what extent of marketed medicines used in the management of high-altitude sickness ...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233710369125

    authors: Ghosh M,Biswas D,Mukherjee A

    更新日期:2010-08-01 00:00:00

  • Some scientific judgments in the assessment of the risk of environmental contaminants.

    abstract::The assessment of risk due to environmental contaminants depends, in part, on scientific data. When such data are incomplete, as is usually the case, assumptions based on scientific judgments are made to analyze the consequences. Specifically, when health related data needed to assess the risk posed by environmental c...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/074823378900500308

    authors: Cothern CR

    更新日期:1989-05-01 00:00:00

  • Fluoride and endosulfan together potentiate cytogenetic effects in Swiss albino mice bone marrow cells.

    abstract::In this study, the cytotoxic potential of fluoride and endosulfan in combination was investigated in Swiss albino mice bone marrow cells using the chromosomal aberration (CA) and micronucleus (MN) test systems. Fluoride (25.1 mg kg-1 body weight [bw] in water) and endosulfan (1.8 mg kg-1 bw by oral intubation) were ad...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233720979423

    authors: Sharma A,John P,Bhatnagar P

    更新日期:2020-12-16 00:00:00

  • Multi-route exposure assessment and biological monitoring of urban pesticide applicators during structural control treatments with chlorpyrifos.

    abstract::A preliminary study of dermal and respiratory exposure to chlorpyrifos (Dursban TC) during structural treatments was conducted with eight workers from a commercial pest control company. The compound was applied by sub-slab and soil injection to four houses, with each application involving two workers. Crawl space appl...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/074823379000600301

    authors: Fenske RA,Elkner KP

    更新日期:1990-05-01 00:00:00

  • In vitro evaluation of cobalt oxide nanoparticle-induced toxicity.

    abstract::Cobalt oxide (Co3O4) nanoparticles have applications in nanomedicine and nanotechnology; therefore, any possible adverse effects require thorough investigation. The present study investigated the effects of Co3O4 nanoparticles on four different cell lines: liver, HepG2 hepatocellular carcinoma cells; lung, A549 lung c...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233717706633

    authors: Abudayyak M,Gurkaynak TA,Özhan G

    更新日期:2017-08-01 00:00:00

  • Genotoxic and oxidative stress potential of nanosized and bulk zinc oxide particles in Drosophila melanogaster.

    abstract::Zinc oxide nanoparticles (ZnONP) are manufactured on a large scale and can be found in a variety of consumer products, such as sunscreens, lotions, paints and food additives. Few studies have been carried out on its genotoxic potential and related mechanisms in whole organisms. In the present study, the in vivo genoto...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233715599472

    authors: Carmona ER,Inostroza-Blancheteau C,Rubio L,Marcos R

    更新日期:2016-12-01 00:00:00

  • Mercuric chloride induced hepatotoxic and hematologic changes in rats: The protective effects of sodium selenite and vitamin E.

    abstract::This study focuses on investigating the possible protective effect of sodium selenite (Na2SeO3) and/or vitamin E against mercuric chloride (HgCl2)-induced hepatotoxicity in rat. Male rats were given HgCl2 (1 mg/kg body weight (bw)) and HgCl2 plus Na2SeO3 (0.25 mg/kg bw) and/or vitamin E (100 mg/kg bw) daily via gavage...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233715572561

    authors: Uzunhisarcikli M,Aslanturk A,Kalender S,Apaydin FG,Bas H

    更新日期:2016-09-01 00:00:00

  • Detection of macrocyclic trichothecene mycotoxin in a caprine (goat) tracheal instillation model.

    abstract::This study demonstrates the detection and dynamics of macrocyclic trichothecene mycotoxin (MTM) tissue loading using a commercially available assay in a goat model. The detection of MTMs has been difficult and complex due to the uncertainty of what tissues to examine and when to sample. Twelve goats (two groups of eac...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233709348275

    authors: Layton RC,Purdy CW,Jumper CA,Straus DC

    更新日期:2009-10-01 00:00:00

  • Hazardous waste site frequency: use of the capture-recapture method.

    abstract::This investigation used a two-source capture-recapture method (CRM) for determining ascertainment and undercounts of non-national priority listed hazardous waste sites in the states of Arizona, Maine and Pennsylvania. These findings suggest that ascertainment of hazardous waste sites vary greatly, with some more accur...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1191/0748233703th179oa

    authors: Lange JH,Chang YF,LaPorte RE,Mastrangelo G

    更新日期:2003-07-01 00:00:00

  • Evaluation of diazinon-induced hepatotoxicity and protective effects of crocin.

    abstract::Diazinon (DZN) is one of the most widely used insecticides in agricultural pest control. Previous studies have shown that DZN may induce hepatotoxicity. Reactive oxygen species and apoptosis pathways are involved in the toxicity of DZN. Crocin, a constituent of saffron, has hepatoprotective effects due to its antioxid...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233713475519

    authors: Lari P,Abnous K,Imenshahidi M,Rashedinia M,Razavi M,Hosseinzadeh H

    更新日期:2015-04-01 00:00:00

  • Thrombocytosis induced in mice after subacute and subchronic V2O5 inhalation.

    abstract::Reports about vanadium (V) inhalation toxicity on the hematopoietic system, specifically about coagulation are limited. Therefore, we decided to evaluate the effects of V with a complete blood count and morphologic analysis of platelets on blood smears. CD-1 male mice inhaled V2O5 0.02 M 1 h twice weekly over 12 weeks...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1191/0748233706th250oa

    authors: González-Villalva A,Fortoul TI,Avila-Costa MR,Piñón-Zarate G,Rodriguez-Laraa V,Martínez-Levy G,Rojas-Lemus M,Bizarro-Nevarez P,Díaz-Bech P,Mussali-Galante P,Colin-Barenque L

    更新日期:2006-04-01 00:00:00

  • Acute myocardial injury following hydrogen sulfide poisoning.

    abstract:BACKGROUND:Hydrogen sulfide poisoning can cause severe myocardial injury, but the damage is subtle and can be easily misdiagnosed. This report presents the dynamic observation of myocardial injury associated with hydrogen sulfide poisoning. CASE REPORT:Two young men presented with symptoms of "lightning-like" death im...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233720945184

    authors: Mo W,Shen J,Huang X,Zhang Y,Zhang Z

    更新日期:2020-10-01 00:00:00

  • Environmental Impact Assessment as a tool for risk management.

    abstract::Environmental Impact Assessment is essentially a process comprising four elements: identification, prediction, evaluation, and monitoring. Properly conducted EIA studies can identify linkages between injurious events and/or activities and their damaging consequences. This aids in making the risk management decision. T...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/074823379100700541

    authors: Ratanachai C

    更新日期:1991-09-01 00:00:00

  • Biochemical modulation of cell energy by 2-deoxyglucose and malonate in 7,12-dimethylbenz(a)anthracene-induced carcinogenesis in rats.

    abstract::The goal of this study was to explore the impact of 2-deoxglucose or malonate individually or in combination on the level of cell energy (adenosine-5'-triphosphate) and oxidative stress in 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary proliferation in rats. A total of 60 adult female Sprague Dawley rats were r...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233712472525

    authors: Moselhy SS,Kumosani TA,Al-Malki AL,Naif AA

    更新日期:2015-04-01 00:00:00

  • Airborne exposure and soil levels associated with lead abatement of a steel tank.

    abstract::This study reports on airborne exposure levels and soil concentrations of lead in regard to abatement of a steel structure (water tank). The tank was de-leaded by abrasive sand blasting. The ball of the tank had a lead surface level that exceeded the Environmental Protection Agency (EPA) definition of lead-based paint...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1191/0748233702th127oa

    authors: Lange JH

    更新日期:2002-02-01 00:00:00

  • Synergistic damage by UVA radiation and pollutants.

    abstract::Not only is skin cancer by far the most common human cancer but also the incidence of skin cancer has been increasing at an alarming rate in recent decades. Fortunately, most people now realize that sun exposure causes unattractive photoaging and skin cancer, so they do apply sunscreens conscientiously. However, until...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章,评审

    doi:10.1177/0748233709106067

    authors: Burke KE,Wei H

    更新日期:2009-05-01 00:00:00

  • Comparative toxicity of Paraquat herbicide and some plant extracts in Lymnaea natalensis snails.

    abstract::Paraquat has been shown to be a highly toxic compound for humans and animals, and many cases of acute poisoning and death have been reported over the past few decades. The present study was undertaken to evaluate comprehensively herbicides (Paraquat) and some plant extracts to biochemical aspects of Lymnaea natalensis...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233713498457

    authors: Bakry FA,Eleiwa ME,Taha SA,Ismil SM

    更新日期:2016-01-01 00:00:00

  • Determining standards for professional divers diving in benzene polluted waters.

    abstract::The main objective of this study is to calculate the hours of diving in benzene-polluted waters acceptable for professional divers. We considered recommended absorption limit as that from pulmonary workplace absorption during an 8-h workday at recommended exposure limits set by the National Institute of Occupational S...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233708098126

    authors: Froom P

    更新日期:2008-09-01 00:00:00

  • Modulating effects of selenium in adrenal medulla of rats exposed to 7,12-dimethylbenz[a]anthracene.

    abstract:OBJECTIVE:The aim of this study was to evaluate the chemopreventive potential of organoselenium compounds (Se I and Se II) in the well-established rat model treated with 7,12-dimethylbenz[a]anthracene (DMBA), by monitoring the extent of tyrosine hydroxylase (TH) activity, adrenomedullin (ADM) level and total RNA level ...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233711432575

    authors: Talas ZS,Ozdemir I,Ates B,Gok Y,Yilmaz I

    更新日期:2013-04-01 00:00:00

  • Acute effects of methiocarb on oxidative damage and the protective effects of vitamin E and taurine in the liver and kidney of Wistar rats.

    abstract::Methiocarb (MC) is a widely used carbamate pesticide in agriculture and health programs. Although the main molecular mechanism of carbamate toxicity involves acetylcholinesterase inhibition, studies have also implicated the induction of oxidative stress. Therefore, the present study was aimed to evaluate the effect of...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233712446719

    authors: Ozden S,Catalgol B,Gezginci-Oktayoglu S,Karatug A,Bolkent S,Alpertunga B

    更新日期:2013-02-01 00:00:00

  • Fatty acid profile and antioxidant status in Venus verrucosa gills as λ-cyhalothrin toxic effects.

    abstract::The aim of this study was to analyze the biochemical alterations in the gills of Venus verrucosa under exposure for 6 days to three doses of lambda-cyhalothrin (λ-cyh) (100, 250, and 500 µg L-1). Malondialdehyde, lipid hydroperoxide, and hydrogen peroxide levels in the gills of treated groups increased. λ-Cyh exposure...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233720961219

    authors: Fouzai C,Trabelsi W,Rabeh I,Bejaoui S,Telahigue K,El Cafsi M,Soudani N

    更新日期:2020-11-01 00:00:00

  • Chronic prenatal exposure to the 900 megahertz electromagnetic field induces pyramidal cell loss in the hippocampus of newborn rats.

    abstract::Widespread use of mobile phones which are a major source of electromagnetic fields might affect living organisms. However, there has been no investigation concerning prenatal exposure to electromagnetic fields or their roles in the development of the pyramidal cells of the cornu ammonis in postnatal life. Two groups o...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233709106442

    authors: Bas O,Odaci E,Mollaoglu H,Ucok K,Kaplan S

    更新日期:2009-07-01 00:00:00

  • In vivo effects of intravenous lipid emulsion on lung tissue in an experimental model of acute malathion intoxication.

    abstract::Malathion can be ingested, inhaled, or absorbed through the skin, but acute toxicity is maximized when administered orally. Intravenous lipid emulsion (ILE) treatment is used as a new therapeutic method in cases of systemic toxicity caused by some lipid soluble agents. This study aimed to examine the potential treatme...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233717748080

    authors: Uysal M,Karaman S

    更新日期:2018-02-01 00:00:00

  • Lys- and Leu-aminopeptidase activity after acute toluene exposure in the rat brain.

    abstract::Changes in Lys- and Leu-aminopeptidase activities in several brain regions of the rat, after acute toluene administration, are described in this research. Aminopeptidase activity has been suggested as a candidate regulator of the degradation of several neuroactive peptides. Lys-aminopeptidase activity was significantl...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/074823379300900310

    authors: De Gandarias JM,Echevarria E,Irazusta J,Casis E,Casis L

    更新日期:1993-05-01 00:00:00

  • Effects of in utero JP-8 jet fuel exposure on the immune systems of pregnant and newborn mice.

    abstract::The US Air Force has implemented the widespread use of JP-8 jet fuel in its operations, although a thorough understanding of its potential effects upon exposed personnel is unclear. Previous work has reported that JP-8 exposure is immunosuppressive. In the present study, the effects of in-utero JP-8 jet fuel exposure ...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233708089045

    authors: Harris DT,Sakiestewa D,He X,Titone D,Witten M

    更新日期:2007-10-01 00:00:00

  • Protective effect of curcumin on acute lung injury induced by intestinal ischaemia/reperfusion.

    abstract::The aim of this study is to evaluate the role of curcumin on acute lung injury induced by intestinal ischaemia/reperfusion (I/R). A total of 30 male Wistar albino rats were divided into 3 groups: sham, I/R, and I/R + curcumin; each group contains 10 animals. Sham group animals underwent laparotomy without I/R injury. ...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233711430984

    authors: Guzel A,Kanter M,Guzel A,Yucel AF,Erboga M

    更新日期:2013-08-01 00:00:00

  • Thymoquinone supplementation ameliorates lead-induced testis function impairment in adult rats.

    abstract::This study was realized to investigate the possible beneficial effect of thymoquinone (TQ), the major active component of volatile oil of Nigella sativa seeds, against lead (Pb)-induced inhibition of rat testicular functions. Adult rats were randomized into four groups: a control group receiving no treatment; a Pb gro...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233714548474

    authors: Mabrouk A,Ben Cheikh H

    更新日期:2016-06-01 00:00:00

  • Prevention of cytotoxicity of nickel by quercetin: the role of reactive oxygen species and histone acetylation.

    abstract::Excessive exposure to nickel may cause health effects on the blood, lung, nose, kidney, reproductive system, skin and the unborn child. In the present study, we found that Ni²⁺ exposure led to a time- and dose-dependent proliferation arrest and death in human leukemia HL-60 cells. In the presence of 1 mM Ni²⁺, reactiv...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233711433940

    authors: Chen J,Han J,Wang J

    更新日期:2013-05-01 00:00:00